lecture (new copd meds)

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Newly Available COPD MedicationsRyan Lally, Yury Viknevich

Overview2Background on Chronic Obstructive Pulmonary Disorder (COPD)Long Acting Muscarinic Antagonists (LAMA)Drug MonographsClinical EvidenceCostRecommendationLong Acting Muscarinic Antagonists / Long Acting Beta 2 Agonists (LAMA/LABA) combinationsDrug MonographsClinical Review/evidenceCostRecommendationSummaryReferencesQuestions/Comments

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Chronic Obstructive Pulmonary Disorder (COPD)Symptoms / Presentation:Dyspnea, chronic cough, and chronic sputum productionOnset in mid-lifeProgressive History of tobacco smoking or exposure to other types of smoke

DiagnosisSpirometry reading of FEV1/FVC < 0.7 confirms presence of airflow limitation and thus COPD

COPD costs healthcare systems 50 billion dollars per year in the United States3

Classification of COPD1ClassSeverityFEV1GOLD 1Mild Fev1 80 % predicted GOLD 2Moderate 50 % FEV1 < 80 % predictedGOLD 3Severe 30 % FEV1 < 50 % predictedGOLD 4 Very severe FEV1 < 30 % predicted

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Classification of COPD (Continued)1PatientCharacteristicSpirometric ClassificationExacerbations per yearmMRCCATALow Risk, Less SymptomsGOLD 1-2 10-1