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Restless Leg Syndrome Medications - What's

Right For You?

By Kathy Lund

R e s t l e s s L e g S y n d r o m e m e d i c a t i o n s

(prescription of course) can be a tricky subject.

We have tried all the self-help, lifestyle changes,

and underlying cause remedies that we can. The

symptoms still exist, sometimes continually

throughout the day and night. Your condition has

been evaluated as severe or very severe

because there is much pain associated with the other bothersome symptoms of RLS. Now is the time to allow your

physician to prescribe a medication for you.

There is a wide variety of medications for RLS which is why the world famous 'trial and error' process will need to take

place. Your own individual type of RLS may not respond or you may have side effects from some medications. In

condensed form, here is a list of prescription drugs used to treat RLS:

Dopaminergic Agents

Considered first-line therapies since they typically alleviate all major features associated with RLS. Dopaminergic

agents have an inhibitory effect on abnormal movements by enhancing levels of t he neurotransmitterdopamine, a

naturally produced chemical that regulates the delivery of messages between nerve cells (neurons) in the central

nervous system. Such medications include bromocriptine mesylate (Parlodel)and pramipexole dihydrochloride

(Mirapex) and ropinirole hydrochloride (Requip(TM)).

Dopamine Precursors

Known as Carbidopa/levodopa is used to control movement in Parkinson's patients. This combination is available as

Sinemet.

Nonergotoline Dopamine Agonists and Other Medications

Best known by advertisements are ropinirole (Requip) and pramipexole (Mirapex).

Benzodiazepines

Interferes with chemical activity in the nervous system and brain, reduces communication between nerve cells. The

benzodiazepine clonazepam (Klonopin) is often prescribed for the treatment of RLS. Other benzodiazepines that may

be recommended as appropriate, suitable alternatives include temazepam (Restoril) , diazepam (Valium), and

triazolam (Halcion).

Wednesday, June, 2011 6:00 PM Posted by SuperbSite

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Opioids

Are natural or artificially produced (synthetic) chemicals that produce opium-like (opiate-like) effects. Opioid agents vary

greatly in potency, ranging from mild to strong. Lo w-potency opioid agents may have beneficial results without risk of

addiction, physicians may consider prescribing opioid agents such as propoxyphene hydrochloride (Darvon) or

codeine in patients with mild, periodic symptoms. The use of higher potency opioid agents such as oxycodone

hydrochloride (Percocet or Roxicodone) or methadone hydrochloride should be reserved for those patients with

severe RLS who have not responded to other appropriate medications.

Anticonvulsants

Is used to help manage or prevent episodes of abnormally increased electrical activity in the brain (seizures).

Anticonvulsants may help relieve some symptoms associated with restless legs syndrome.carbamazepine (Tegretol),

a medication that reduces synaptic transmission, has been shown to decrease restlessness, sensory abnormalities,

and sleep disturbances. However, it is thought that the medication may be less effective in reducing associated

involuntary movements.

Gabapentin (Neurontin) has shown promise as a potential treatment for individuals with RLS. Gabapentin seems to be

most effective in those with mild or moderate RLS who experience actual leg pain. Alternatives including valproate

(Depakene), a medication derived from carboxylic acid, or lamotrigine (Lamictal ).

Other Medications

Clonidine hydrochloride (Catapres) may alleviate leg discomfort and sleep difficulties in some people with RLS; but the

medication may not be effective in reducing associated involuntary movements.

Additional Drug Treatments

Medications thought to relieve RLS symptoms, such as baclofen (Lioresal), a muscle relaxant that is thought to block

nerve activity in the spinal cord has been reported to control symptoms. No controlled studies have been evaluated on

these medications as of yet. Large-scale clinical trials would be helpful in evaluating the use of such medications and

assessing their long-term safety and effectiveness in the treatment of patients with restless legs syndrome.

Be aware that all of these Restless Leg Syndrome medications do come with side effects. The extent and duration of

the side effects totally depends on which drug, which combination, and what dosage is given. Is it worth the agony to

be on the medication? That will depend on how you react and how severe the impact of these medications and your

Restless Leg Syndrome.

Chances are that you will need to try different medications and cross off your list the ones that don't seem to work.

Maybe even combinations of these medications. The best advice to handle this situation is to keep a journal documenting

the prescriptions along with how you respond to these drugs. This is something that your physician will appreciate in

adjusting or changing your medication.

Trying to find out what Restless Leg Syndrome medications are the right ones for you and will be effective can be as

complicated as the disease it's self. Well, almost! Kathy Lund wants you to find out more about what doctors are

prescribing for Restless Leg Syndrome by visiting http://CrazyLegs.info

Know what your medication options are. Be RLS educated.

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http://crazylegs.info/http://www.crazylegs.info/


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klonopin for rls

The world of Restless Leg Syndrome medications is complex and confusing. Find out

how to sort out the medications which should address your RLS.

Wednesday,June, 2011 6:00 PM Posted by SuperbSite

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