jyrki törnvall, mesimäki, risto kontio
DESCRIPTION
Jaw bone defect – Soft tissue defect. Jyrki Törnvall, Mesimäki, Risto Kontio. Preop. May 07. ASCs , ß TCP , BMP 2. From FAT to bone in few months. In the OR. In the Lab. 1) 1dl fat containing 100 000 stem cells. 2) Fat is broken to 1-cell suspension - PowerPoint PPT PresentationTRANSCRIPT
Jyrki Törnvall, Mesimäki, Risto Kontio
Jaw bone defect – Soft tissue defect
Preop
May 07
ASCs,ßTCP,BMP 2
Suomen Kuvalehti
In the OR In the Lab
2) Fat is broken to 1-cell suspensionand stem cells extracted
3) Stem cells and expanded to abt 1 million
4) Cells are combined with biomaterial and GF is added
5) The combination is placed in a titanium cage
1) 1dl fat containing 100 000 stem cells
6) The construct is placed in a prepared muscle pouch
7) The TRAM-flap combination is raised and transplanted to the defect site. It is rigidly fixed with titanium screws.
From FAT to bone in few months
October 07
October 07
December 07
March 08
October 08
1) Harvest adipose tissue
3) Combine cells with growth
factor BMP-2 and biomaterial
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= growth factor*= biomaterial
2) Isolate and culture
adipose stem cells (10 days
)
4) The mix is placed directly
into the patients defect site
= adipose tissue
Ameloblastoma treatment using adipose stem cells and biomaterials