jonah vaccine program
TRANSCRIPT
Appendix B
B
APPENDIX BVaccines
U.S. Vaccines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-1
Selected Discontinued U.S. Vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-5
Vaccine Excipient and Media Summary, by Excipient . . . . . . . . . . . . . . . . . . B-7
Vaccine Excipient and Media Summary, by Vaccine . . . . . . . . . . . . . . . . . . B-14
Latex in Vaccine Packaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-17
Thimerosal Table . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-19
Foreign Language Terms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-21
Appendix B
B
Appendix B
B
B-1
U.S
. Vac
cine
s Va
ccin
e Tr
ade
Nam
e A
bbre
viat
ion
Man
ufac
ture
r Ty
pe
Rou
te
Com
men
ts
Ant
hrax
B
ioTh
rax
AV
A
Em
erge
nt
BioS
olut
ions
In
activ
ated
Bac
teria
l IM
DTa
P
Dap
tace
l D
TaP
sano
fi In
activ
ated
Bac
teria
l IM
Te
tanu
s &
diph
ther
ia to
xoid
s an
d ac
ellu
lar p
ertu
ssis
vac
cine
.
Infa
nrix
D
TaP
G
laxo
Sm
ithK
line
Inac
tivat
ed B
acte
rial
IM
Teta
nus
& di
phth
eria
toxo
ids
and
acel
lula
r per
tuss
is v
acci
ne.
Trip
edia
D
TaP
sano
fi In
activ
ated
Bac
teria
l IM
Te
tanu
s &
diph
ther
ia to
xoid
s an
d ac
ellu
lar p
ertu
ssis
vac
cine
.
DT
Gen
eric
D
T sa
nofi
Inac
tivat
ed B
acte
rial
Toxo
ids
IM
Ped
iatri
c fo
rmul
atio
n (t
hrou
gh a
ge
6).
DTa
P/H
ib
TriH
IBit
DTa
P/H
ib
sano
fi In
activ
ated
Bac
teria
l IM
A
ctH
IB re
cons
titut
ed w
ith T
riped
ia.
Lice
nsed
for 4
th d
ose
of D
TaP
& H
ib
serie
s.
DTa
P�–I
PV
K
inrix
D
TaP
-IPV
G
laxo
Sm
ithK
line
Inac
tivat
ed B
acte
rial &
V
iral
IM
Lice
nsed
for 5
th (D
TaP
) and
4th
(IP
V)
boos
ter a
t 4-6
yea
rs.
DTa
P-H
epB
-IPV
P
edia
rix
DTa
P-H
epB
-IPV
G
laxo
Sm
ithK
line
Inac
tivat
ed B
acte
rial &
V
iral
IM
Lice
nsed
for d
oses
at 2
, 4, &
6
mon
ths
(thro
ugh
6 ye
ars
of a
ge).
Not
lic
ense
d fo
r boo
ster
s.
DTa
P-IP
V/H
ib
Pen
tace
l D
TaP
-IPV
/Hib
sa
nofi
Inac
tivat
ed B
acte
rial &
V
iral
IM
Lice
nsed
for 4
dos
es a
t 2, 4
, 6, a
nd
15-1
8 m
onth
s.
type
b
(Hib
)
Ped
vaxH
IB
Hib
M
erck
In
activ
ated
Bac
teria
l IM
PR
P-O
MP.
Pol
ysac
char
ide
conj
ugat
e (m
enin
g. p
rote
in c
arrie
r).
2-do
se p
rimar
y sc
hedu
le.
Act
HIB
H
ib
sano
fi In
activ
ated
Bac
teria
l IM
PR
P-T.
Pol
ysac
char
ide
conj
ugat
e (te
tanu
s to
xoid
car
rier)
. 3-
dose
prim
ary
sche
dule
.
Hib
erix
H
ib
Gla
xoS
mith
Klin
e In
activ
ated
Bac
teria
l IM
Po
lysa
ccha
ride
conj
ugat
e (te
tanu
s to
xoid
car
rier)
. Boo
ster
onl
y.
type
b �–
he
patit
is B
C
omva
x H
ib-H
epB
M
erck
In
activ
ated
Bac
teria
l &
Vira
l IM
S
houl
d no
t be
used
for h
epB
birt
h do
se.
Hep
atiti
s A
Hav
rix
Hep
A
Gla
xoS
mith
Klin
e In
activ
ated
Vira
l IM
Ped
iatri
c (<
18) a
nd a
dult
form
ulat
ions
. P
edia
tric
= 72
0 E
L.U
., 0.
5mL
Adu
lt =
1,44
0 E
L.U
., 1.
0mL
Min
imum
age
= 1
yea
r
Vaq
ta
Hep
A
Mer
ck
Inac
tivat
ed V
iral
IM
Ped
iatri
c (<
18) a
nd a
dult
form
ulat
ions
. P
edia
tric
= 25
U. 0
.5m
L A
dult
= 50
U. 1
.0m
L M
inim
um a
ge =
1 y
ear
Appendix B
B
B-2
Vacc
ine
Trad
e N
ame
Abb
revi
atio
n M
anuf
actu
rer
Type
R
oute
C
omm
ents
Hep
atiti
s B
Eng
erix
-B
Hep
B
Gla
xoS
mith
Klin
e In
activ
ated
Vira
l IM
P
edia
tric
(<19
) and
adu
lt fo
rmul
atio
ns. P
edia
tric
form
ulat
ion
not l
icen
sed
for a
dults
.
Rec
ombi
vax
HB
H
epB
M
erck
In
activ
ated
Vira
l IM
P
edia
tric
(<19
), ad
ult,
and
dial
ysis
fo
rmul
atio
ns. T
wo
pedi
atric
dos
es
may
be
subs
titut
ed fo
r an
adul
t dos
e.
Hep
atiti
s A
-H
epat
itis
B
Twin
rix
Hep
A-H
epB
G
laxo
Sm
ithK
line
Inac
tivat
ed V
iral
IM
Ped
iatri
c do
se o
f Hep
A +
adu
lt do
se
of H
epB
. M
inim
um a
ge =
18
year
s.
3-do
se ro
utin
e se
ries
(4-d
ose
alte
rnat
e sc
hedu
le fo
r rap
id
prot
ectio
n).
Her
pes
Zost
er
(Shi
ngle
s)
Zost
avax
ZO
S
Mer
ck
Live
Atte
nuat
ed V
iral
SC
Li
cens
ed fo
r age
60
and
olde
r.
Hum
an
Pap
illom
aviru
s (H
PV
)
Gar
dasi
l H
PV
4 M
erck
In
activ
ated
Vira
l IM
Q
uadr
ival
ent (
type
s 6,
11,
16,
18)
. Li
cens
ed fo
r mal
es a
nd fe
mal
es
9 th
roug
h 26
yea
rs.
Cer
varix
H
PV
2 G
laxo
Sm
ithK
line
Inac
tivat
ed V
iral
IM
Biv
alen
t (ty
pes
16, 1
8). L
icen
sed
for
fem
ales
10
thro
ugh
26 y
ears
.
Influ
enza
(sea
sona
l)
Flua
rix
TIV
G
laxo
Sm
ithK
line
Inac
tivat
ed V
iral
IM
Triv
alen
t typ
es A
& B
. M
inim
um a
ge =
3 y
ears
.
Fluv
irin
TIV
C
hiro
n In
activ
ated
Vira
l IM
Tr
ival
ent t
ypes
A &
B, p
urifi
ed
surfa
ce a
ntig
en.
Min
imum
age
= 4
yea
rs.
Fluz
one
TIV
sano
fi In
activ
ated
Vira
l IM
Triv
alen
t typ
es A
& B
, sub
virio
n.
Min
imum
age
(mul
tidos
e vi
al) =
6
mo.
Ag
e ra
nge
(0.2
5mL
pref
illed
syr
inge
) =
6 th
roug
h 35
mo.
M
inim
um a
ge (0
.5m
L pr
efill
ed
syrin
ge) =
3 y
ears
.
FluL
aval
TI
V G
laxo
Smith
Klin
e In
activ
ated
Vira
l IM
Tr
ival
ent t
ypes
A &
B.
Min
imum
age
= 1
8 ye
ars.
Aflu
ria
TIV
C
SL
Inac
tivat
ed V
iral
IM
Triv
alen
t typ
es A
& B
. M
inim
um a
ge =
6 m
onth
s.
Agr
iflu
TIV
Nov
artis
In
activ
ated
Vira
l IM
Tr
ival
ent t
ypes
A &
B.
Min
imum
age
18
year
s.
FluM
ist
LAIV
M
edim
mun
e Li
ve A
ttenu
ated
Vira
l In
trana
sal
Triv
alen
t typ
es A
& B
. Ag
e ra
nge
= 2
thro
ugh
49 y
ears
.
Japa
nese
en
ceph
aliti
s
JE-V
AX
JE
sa
nofi
Inac
tivat
ed V
iral
SC
3-
dose
ser
ies.
Ixia
ro
JE
Nov
artis
In
activ
ated
Vira
l IM
Li
cens
ed fo
r age
17
and
olde
r. 2-
dose
ser
ies.
M
easl
es, M
umps
, R
ubel
la
M-M
-R II
M
MR
M
erck
Li
ve A
ttenu
ated
Vira
l S
C
Appendix B
B
B-3
Vacc
ine
Trad
e N
ame
Abb
revi
atio
n M
anuf
actu
rer
Type
R
oute
C
omm
ents
M
easl
es, M
umps
, R
ubel
la, V
aric
ella
P
roQ
uad
MM
RV
M
erck
Li
ve A
ttenu
ated
Vira
l SC
Ag
e ra
nge
= 1
thro
ugh
12 y
ears
.
Men
ingo
cocc
al
Men
omun
e M
PSV4
sa
nofi
Inac
tivat
ed B
acte
rial
SC
P
olys
acch
arid
e (s
erog
roup
s A
, C, Y
, W
135)
. Min
imum
age
= 2
yea
rs.
Men
actra
M
CV
4 sa
nofi
Inac
tivat
ed B
acte
rial
IM
Pol
ysac
char
ide
conj
ugat
e (d
ipht
heria
to
xoid
car
rier,
sero
grou
ps A
, C, Y
, W
135)
. Ag
e ra
nge
= 2
thro
ugh
55 y
ears
.
Men
veo
MC
V4
Nov
artis
In
activ
ated
Bac
teria
l IM
Pol
ysac
char
ide
conj
ugat
e (d
ipht
heria
to
xoid
car
rier,
sero
grou
ps A
, C, Y
, W
135)
. Ag
e ra
nge
= 2
thro
ugh
55 y
ears
.
Pneu
moc
occa
l
Pne
umov
ax 2
3 P
PS
V23
M
erck
In
activ
ated
Bac
teria
l S
C o
r IM
P
olys
acch
arid
e (c
onta
ins
23 s
train
s).
Min
imum
age
= 2
yea
rs.
Pre
vnar
P
CV
7 W
yeth
In
activ
ated
Bac
teria
l IM
Pol
ysac
char
ide
conj
ugat
e (d
ipht
heria
pr
otei
n ca
rrier
, con
tain
s 7
stra
ins)
. R
outin
e ag
e ra
nge
= 2
thro
ugh
59
mon
ths.
Pre
vnar
13
PC
V13
W
yeth
In
activ
ated
Bac
teria
l IM
P
olys
acch
arid
e co
njug
ate
(dip
hthe
ria
prot
ein
carri
er, c
onta
ins
13 s
train
s).
Pol
io
Ipol
IP
V
sano
fi In
activ
ated
Vira
l S
C o
r IM
Tr
ival
ent,
Type
s 1,
2, 3
Rab
ies
Imov
ax R
abie
s
sano
fi In
activ
ated
Vira
l IM
Rab
Ave
rt
Chi
ron
Inac
tivat
ed V
iral
IM
Rot
aviru
s
Rot
a Te
q R
V5
Mer
ck
Live
Vira
l O
ral
Pen
tava
lent
. Firs
t dos
e be
twee
n 6
wee
ks a
nd 1
4 w
eeks
6 d
ays;
co
mpl
ete
3-do
se s
erie
s by
8 m
onth
s 0
days
.
Rot
arix
R
V1
Gla
xoS
mith
Klin
e Li
ve V
iral
Ora
l
Mon
oval
ent.
Firs
t dos
e be
twee
n 6
wee
ks a
nd 1
4 w
eeks
6 d
ays;
co
mpl
ete
2-do
se s
erie
s by
8 m
onth
s 0
days
.
Teta
nus
�–
(redu
ced)
Dip
hthe
ria
Dec
avac
Td
sa
nofi
Inac
tivat
ed B
acte
rial
Toxo
ids
IM
Adu
lt fo
rmul
atio
n (a
ge 7
and
old
er).
(Gen
eric
) Td
M
assa
chus
etts
Bi
olog
ical
Lab
s In
activ
ated
Bac
teria
l To
xoid
s IM
A
dult
form
ulat
ion
(age
7 a
nd o
lder
).
Appendix B
B
B-4
Vacc
ine
Trad
e N
ame
Abb
revi
atio
n M
anuf
actu
rer
Type
R
oute
C
omm
ents
Teta
nus
�– (re
duce
d) D
ipht
heria
(re
duce
d) P
ertu
ssis
Boo
strix
Td
ap
Gla
xoS
mith
Klin
e In
activ
ated
Bac
teria
l IM
Te
tanu
s an
d di
phth
eria
toxo
ids
& pe
rtuss
is v
acci
ne.
Age
rang
e 10
thro
ugh
64 y
ears
.
Adac
el
Tdap
sa
nofi
Inac
tivat
ed B
acte
rial
IM
Teta
nus
and
diph
ther
ia to
xoid
s &
acel
lula
r per
tuss
is v
acci
ne.
Age
rang
e 11
thro
ugh
64 y
ears
.
Teta
nus
toxo
id
(Gen
eric
) TT
sa
nofi
Inac
tivat
ed B
acte
rial
Toxo
id
IM
May
be
used
for a
dults
or c
hild
ren.
Typh
oid
Typh
im V
i
sano
fi In
activ
ated
Bac
teria
l IM
P
olys
acch
arid
e
Viv
otif
Ber
na
B
erna
Li
ve A
ttenu
ated
B
acte
rial
Ora
l Ty
21a
stra
in.
Var
icel
la
Var
ivax
V
AR
M
erck
Li
ve A
ttenu
ated
Vira
l S
C
Vacc
inia
(Sm
allp
ox)
ACAM
2000
Acam
bis
Live
Atte
nuat
ed V
iral
Per
cuta
neou
s
Yel
low
Fev
er
YF-
Vax
Y
F sa
nofi
Live
Atte
nuat
ed V
iral
SC
M
inim
um a
ge =
9 m
onth
s.
Janu
ary
2011
Th
e ab
brev
iatio
ns o
n th
is ta
ble
(Col
umn
3) w
ere
stan
dard
ized
join
tly b
y st
aff o
f the
Cen
ters
for D
isea
se C
ontro
l and
Pre
vent
ion,
A
CIP
Wor
k G
roup
s, th
e ed
itor o
f the
(
), th
e ed
itor o
f (t
he
), A
CIP
mem
bers
, and
liai
son
orga
niza
tions
to th
e A
CIP
. Th
ese
abbr
evia
tions
are
inte
nded
to p
rovi
de a
uni
form
app
roac
h to
vac
cine
refe
renc
es u
sed
in A
CIP
Rec
omm
enda
tions
and
Pol
icy
Not
es p
ublis
hed
in th
e , t
he
, and
the
Am
eric
an A
cade
my
of P
edia
trics
, a
nd in
the
U.S
. im
mun
izat
ion
sche
dule
s fo
r chi
ldre
n, a
dole
scen
ts, a
nd a
dults
. A
das
h (-
) in
an a
bbre
viat
ion
for a
com
bina
tion
vacc
ine
indi
cate
s pr
oduc
ts th
at a
re s
uppl
ied
in th
eir f
inal
form
by
the
man
ufac
ture
r an
d do
not
requ
ire m
ixin
g or
reco
nstit
utio
n. A
sla
sh (/
) ind
icat
es p
rodu
cts
that
mus
t be
mix
ed o
r rec
onst
itute
d by
the
user
.
Appendix B
B
B-5
Selected Discontinued U.S. Vaccines Trade Name Antigen(s) Years
Acel-Imune DTaP 1991-2001 Attenuvax-Smallpox Measles-Smallpox 1967 b-CAPSA-1 Hib (polysaccharide) 1985-89 Biavax Rubella-Mumps (live) BioRab Rabies 1988-2007 Cendevax Rubella (live) 1969-79 Certiva DTaP 1998-2000 Dip-Pert-Tet DTP Diptussis Diphtheria/Pertussis 1949-55 Dryvax Vaccinia 1944-2008 Ecolarix Measles-Rubella (live) Flu Shield Influenza Fluogen Influenza Heptavax-B Hepatitis B (plasma derived) 1981-90 HIB-Immune Hib (polysaccharide) 1985-89 HibTITER Hib (conjugate) 1990-2007 HIB-Vax Hib (polysaccharide) 1985-89 Liovax Smallpox Lirubel Measles-Rubella (live) 1974-78 Lirugen Measles (live) 1965-76 Lymerix Lyme disease 1998-2002 M-Vac Measles 1963-79 M-M-Vax Measles-Mumps (live) 1973 Meningovax Meningococcal Mevilin-L Measles (live) MOPV Polio (live, oral, monovalent �– types I, II, III) Mumpsvax Mumps (live) OmniHIB Hib (conjugate) Orimune Polio (live, oral) 1961-2000 Perdipigen Diphtheria-Pertussis 1949-55 Pfizer-Vax Measles-K Measles (inactivated) 1963-68 Pfizer-Vax Measles-L Measles (live) 1965-70
Pnu-Imune Pneumococcal (polysaccharide 14- or 23-valent) 1977-83
Poliovax Polio (inactivated) 1988-91 ProHIBit Hib (conjugate) 1987-2000 Purivax Polio (inactivated) 1956-65 Quadrigen DTP-Polio 1959-68 Rabies Iradogen Rabies 1908-57 RotaShield Rotavirus 1998-99 Rubelogen Rubella (live) 1969-72 Rubeovax Measles (live) 1963-71 Serobacterin Pertussis 1945-54 Solgen DTP 1962-77 Tetra-Solgen DTP-Polio 1959-68 Tetramune DTP-Hib
Appendix B
B
B-6
Trade Name Antigen(s) Years Tetravax DTP-Polio 1959-65 Topagen Pertussis (intranasal) Tri-Immunol DTP Tridipigen DTP Trinfagen No. 1 DT-Polio Early 1960s Trinivac DTP 1952-64 Trivivac DTP Wyvac Rabies 1982-85
Appendix B
B
B-7
Appendix B
B
B-8
Appendix B
B
B-9
Appendix B
B
B-10
Appendix B
B
B-11
Appendix B
B
B-12
Appendix B
B
B-13
Reprinted courtesy of Grabenstein JD. ImmunoFacts: Vaccines & Immunologic Drugs. St. Louis, MO: Wolters Kluwer Health, Inc.; 2009.
Appendix B
B
B-14
Includes vaccine ingredients (e.g., adjuvants and preservatives) as well as substances used during the manufacturing process, including vaccine-production media, that are removed from the final product and present only in trace quantities.
In addition to the substances listed, most vaccines contain Sodium Chloride (table salt).
Anthrax (BioThrax) Aluminum Hydroxide, Amino Acids, Benzethonium Chloride, Formaldehyde or Formalin, Inorganic Salts and Sugars, Vitamins
BCG (Tice) Asparagine, Citric Acid, Lactose, Glycerin, Iron Ammonium Citrate, Magnesium Sulfate, Potassium Phosphate
DTaP (Daptacel) Aluminum Phosphate, Ammonium Sulfate, Casamino Acid, Dimethyl-beta-cyclodextrin, Formaldehyde or Formalin, Glutaraldehyde, 2-Phenoxyethanol
DTaP (Infanrix) Aluminum Hydroxide, Bovine Extract, Formaldehyde or Formalin, Glutaraldhyde, 2-Phenoxyethanol, Polysorbate 80
DTaP (Tripedia) Aluminum Potassium Sulfate, Ammonium Sulfate, Bovine Extract, Formaldehyde or Formalin, Gelatin, Polysorbate 80, Sodium Phosphate, Thimerosal*
DTaP/Hib (TriHIBit) Aluminum Potassium Sulfate, Ammonium Sulfate, Bovine Extract, Formaldehyde or Formalin, Gelatin, Polysorbate 80, Sucrose, Thimerosal*
DTaP-IPV (Kinrix) Aluminum Hydroxide, Bovine Extract, Formaldehyde, Lactalbumin Hydrolysate, Monkey Kidney Tissue, Neomycin Sulfate, Polymyxin B, Polysorbate 80
DTaP-HepB-IPV (Pediarix) Aluminum Hydroxide, Aluminum Phosphate, Bovine Protein, Lactalbumin Hydrolysate, Formaldehyde or Formalin, Glutaraldhyde, Monkey Kidney Tissue, Neomycin, 2-Phenoxyethanol, Polymyxin B, Polysorbate 80, Yeast Protein
DtaP-IPV/Hib (Pentacel) Aluminum Phosphate, Bovine Serum Albumin, Formaldehyde, Glutaraldhyde, MRC-5 DNA and Cellular Protein, Neomycin, Polymyxin B Sulfate, Polysorbate 80, 2-Phenoxyethanol,
DT (sanofi) Aluminum Potassium Sulfate, Bovine Extract, Formaldehyde or Formalin, Thimerosal (multi-dose) or Thimerosal* (single-dose)
DT (Massachusetts) Aluminum Hydroxide, Formaldehyde or Formalin
Hib (ACTHib) Ammonium Sulfate, Formaldehyde or Formalin, Sucrose
Hib (Hiberix) Formaldehyde or Formalin, Lactose
Hib (PedvaxHib) Aluminum Hydroxyphosphate Sulfate
Hib/Hep B (Comvax) Amino Acids, Aluminum Hydroxyphosphate Sulfate, Dextrose, Formaldehyde or Formalin, Mineral Salts, Sodium Borate, Soy Peptone, Yeast Protein
Hep A (Havrix) Aluminum Hydroxide, Amino Acids, Formaldehyde or Formalin, MRC-5 Cellular Protein, Neomycin Sulfate, 2-Phenoxyethanol, Phosphate Buffers, Polysorbate
Hep A (Vaqta) Aluminum Hydroxyphosphate Sulfate, Bovine Albumin or Serum, DNA, Formaldehyde or Formalin, MRC-5 Cellular Protein, Sodium Borate
Hep B (Engerix-B) Aluminum Hydroxide, Phosphate Buffers, Thimerosal*, Yeast Protein
Hep B (Recombivax) Aluminum Hydroxyphosphate Sulfate, Amino Acids, Dextrose, Formaldehyde or Formalin, Mineral Salts, Potassium Aluminum Sulfate, Soy Peptone, Yeast Protein
HepA/HepB (Twinrix) Aluminum Hydroxide, Aluminum Phosphate, Amino Acids, Dextrose, Formaldehyde or Formalin, Inorganic Salts, MRC-5 Cellular Protein, Neomycin Sulfate, 2-Phenoxyethanol, Phosphate Buffers, Polysorbate 20, Thimerosal*, Vitamins, Yeast Protein
Human Papillomavirus (HPV) (Cerverix)
3-O-desacyl-4�’-monophosphoryl lipid A (MPL), Aluminum Hydroxide, Amino Acids, Insect Cell Protein, Mineral Salts, Sodium Dihydrogen Phosphate Dihydrate, Vitamins
Appendix B
B
B-15
Human Papillomavirus (HPV) (Gardasil)
Amino Acids, Amorphous Aluminum Hydroxyphosphate Sulfate, Carbohydrates, L-histidine, Mineral Salts, Polysorbate 80, Sodium Borate, Yeast Protein, Vitamins
Influenza (Afluria) Beta-Propiolactone, Calcium Chloride, Neomycin, Ovalbumin, Polymyxin B, Potassium Chloride, Potassium Phosphate, Sodium Phosphate, Sodium Taurodeoxychoalate
Influenza (Agriflu) Cetyltrimethylammonium Bromide (CTAB), Egg Protein, Formaldehyde or Formalin, Kanamycin, Neomycin Sulfate, Polysorbate 80
Influenza (Fluarix) Egg Albumin (Ovalbumin), Egg Protein, Formaldehyde or Formalin, Gentamicin, Hydrocortisone, Octoxynol-10, -Tocopheryl Hydrogen Succinate, Polysorbate 80, Sodium Deoxycholate, Sodium Phosphate, Thimerosal*
Influenza (Flulaval) Egg Albumin (Ovalbumin), Egg Protein, Formaldehyde or Formalin, Sodium Deoxycholate, Phosphate Buffers, Thimerosal
Influenza (Fluvirin) Beta-Propiolactone , Egg Protein, Neomycin, Polymyxin B, Polyoxyethylene 9-10 Nonyl Phenol (Triton N-101, Octoxynol 9), Thimerosal (multidose containers), Thimerosal* (single-dose syringes)
Influenza (Fluzone) Egg Protein, Formaldehyde or Formalin, Gelatin, Octoxinol-9 (Triton X-100), Thimerosal (multidose containers)
Influenza (FluMist) Chick Kidney Cells, Egg Protein, Gentamicin Sulfate, Monosodium Glutamate, Sucrose Phosphate Glutamate Buffer
IPV (Ipol) Calf Serum Protein, Formaldehyde or Formalin, Monkey Kidney Tissue, Neomycin, 2-Phenoxyethanol, Polymyxin B, Streptomycin,
Japanese Encephalitis (JE-Vax) Formaldehyde or Formalin, Gelatin, Mouse Serum Protein, Polysorbate 80, Thimerosal
Japanese Encephalitis (Ixiaro) Aluminum Hydroxide, Bovine Serum Albumin, Formaldehyde, Protamine Sulfate, Sodium Metabisulphite
Meningococcal (Menactra) Formaldehyde or Formalin, Phosphate Buffers
Meningococcal (Menomune) Lactose, Thimerosal (10-dose vials only)
Meningococcal (Menveo) Amino Acid, Formaldehyde or Formalin, Yeast
MMR (MMR-II) Amino Acid, Bovine Albumin or Serum, Chick Embryo Fibroblasts, Human Serum Albumin, Gelatin, Glutamate, Neomycin, Phosphate Buffers, Sorbitol, Sucrose, Vitamins
MMRV (ProQuad)
Bovine Albumin or Serum, Gelatin, Human Serum Albumin, Monosodium L-glutamate, MRC-5 Cellular Protein, Neomycin, Sodium Phosphate Dibasic, Sodium Bicarbonate, Sorbitol, Sucrose, Potassium Phosphate Monobasic, Potassium Chloride, Potassium Phosphate Dibasic
Pneumococcal (Pneumovax) Bovine Protein, Phenol
Pneumococcal (Prevnar) Aluminum Phosphate, Amino Acid, Soy Peptone, Yeast Extract
Pneumococcal (Prevnar 13) Aluminum Phosphate, Amino Acid, Polysorbate 80, Soy Peptone, Succinate Buffer, Yeast Extract
Rabies (Imovax) Human Serum Albumin, Beta-Propiolactone, MRC-5 Cellular Protein, Neomycin, Phenol Red (Phenolsulfonphthalein), Vitamins
Rabies (RabAvert) Amphotericin B, Beta-Propiolactone, Bovine Albumin or Serum, Chicken Protein, Chlortetracycline, Egg Albumin (Ovalbumin), Ethylenediamine-Tetraacetic Acid Sodium (EDTA), Neomycin, Potassium Glutamate
Rotavirus (RotaTeq) Cell Culture Media, Fetal Bovine Serum, Sodium Citrate, Sodium Phosphate Monobasic Monohydrate, Sodium Hydroxide Sucrose, Polysorbate 80
Rotavirus (Rotarix)
Amino Acids, Calcium Carbonate, Calcium Chloride, D-glucose, Dextran, Ferric (III) Nitrate, L-cystine, L-tyrosine, Magnesium Sulfate, Phenol Red, Potassium Chloride, Sodium Hydrogenocarbonate, Sodium Phosphate, Sodium L-glutamine, Sodium Pyruvate, Sorbitol, Sucrose, Vitamins, Xanthan
Appendix B
B
B-16
Td (Decavac) Aluminum Potassium Sulfate, Bovine Extract, Formaldehyde or Formalin, 2-Phenoxyethanol, Peptone, Thimerosal*
Td (Massachusetts) Aluminum Hydroxide, Aluminum Phosphate, Formaldehyde or Formalin, Thimerosal (some multidose containers)
Tdap (Adacel) Aluminum Phosphate, Formaldehyde or Formalin, Glutaraldehyde, 2-Phenoxyethanol
Tdap (Boostrix) Aluminum Hydroxide, Bovine Extract, Formaldehyde or Formalin, Glutaraldehyde, Polysorbate 80
Typhoid (inactivated �– Typhim Vi)
Disodium Phosphate, Monosodium Phosphate, Phenol, Polydimethylsilozone, Hexadecyltrimethylammonium Bromide
Typhoid (oral �– Ty21a) Amino Acids, Ascorbic Acid, Bovine Protein, Casein, Dextrose, Galactose, Gelatin, Lactose, Magnesium Stearate, Sucrose, Yeast Extract
Vaccinia (ACAM2000) Glycerin, Human Serum Albumin, Mannitol, Monkey Kidney Cells, Neomycin, Phenol, Polymyxin B
Varicella (Varivax) Bovine Albumin or Serum, Ethylenediamine-Tetraacetic Acid Sodium (EDTA), Gelatin, Monosodium L-Glutamate, MRC-5 DNA and Cellular Protein, Neomycin, Potassium Chloride, Potassium Phosphate Monobasic, Sodium Phosphate Monobasic, Sucrose
Yellow Fever (YF-Vax) Egg Protein, Gelatin, Sorbitol
Zoster (Zostavax) Bovine Calf Serum, Hydrolyzed Porcine Gelatin, Monosodium L-glutamate, MRC-5 DNA and Cellular Protein, Neomycin, Potassium Phosphate Monobasic, Potassium Chloride, Sodium Phosphate Dibasic, Sucrose
March 2010 *Where �“thimerosal�” is marked with an asterisk (*) it indicates that the product should be considered equivalent to thimerosal-free products. This vaccine may contain trace amounts (<0.3 mcg) of mercury left after post-production thimerosal removal, but these amounts have no biological effect. JAMA 1999;282(18) and JAMA 2000;283(16) Adapted from Grabenstein JD. ImmunoFacts: Vaccines & Immunologic Drugs. St. Louis, MO: Wolters Kluwer Health Inc.; 2009 and individual products�’ package inserts. All reasonable efforts have been made to ensure the accuracy of this information, but manufacturers may change product contents before that information is reflected here.
Appendix B
B
B-17
�“If a person reports a severe (anaphylactic) allergy to latex, vaccines supplied in vials or syringes that contain natural rubber should not be administered unless the benefit of vaccination outweighs the risk for a potential allergic reaction. In these cases, providers should be prepared to treat patients who are having an allergic reaction. For latex allergies other than anaphylactic allergies (e.g., a history of contact allergy to latex gloves), vaccines supplied in vials or syringes that contain dry natural rubber or rubber latex may be administered.�” (ACIP . 2011) The following table is accurate, to the best of our knowledge, as of February 2011.
Anthrax (BioThrax) YES �– Vial Comvax YES �– Vial
DTaP
Daptacel YES �– Vial
Infanrix YES �– Syringe NO �– Vial
Tripedia YES �– Vial DT (Generic) YES �– Vial
Hib
Hiberix NO PedvaxHIB Yes �– Vial
ActHIB YES �– Diluent vial NO �– Lyophilized vaccine vial
Hepatitis A Havrix YES �– Syringe
NO �– Vial
Vaqta YES �– Vial YES �– Syringe
Hepatitis B Engerix-B YES �– Syringe NO �– Vial
Recombivax HB YES �– Vial
HPV Gardasil NO
Cerverix YES �– Syringe NO �– Vial
Influenza
Fluarix YES �– Syringe Fluvirin NO Fluzone NO FluLaval NO Afluria NO Agriflu NO FluMist NO
Japanese Encephalitis
JE-Vax NO Ixiaro NO
Kinrix YES �– Syringe NO �– Vial
MMR (M-M-R II) NO MMRV (ProQuad) NO
Measles (Attenuvax) NO
Appendix B
B
B-18
Mumps (Mumpsvax) NO Rubella (Meruvax II) NO
Meningococcal
Menomune YES �– Vial
Menactra YES �– Vial NO �– Syringe
Menveo NO
Pediarix YES �– Syringe NO �– Vial
Pentacel NO
Pneumococcal
Pneumovax 23 NO
Prevnar YES �– Syringe, prior to Lot #D46873 NO �– Syringe, Lot #D46873 and after
Prevnar 13 NO
Polio (IPOL) YES �– Syringe NO �– Vial
Rabies Imovax Rabies NO RabAvert NO
Rotavirus RotaTeq NO
Rotarix YES �– Applicator NO �– Vial & Transfer Adapter
Td Decavac NO �– Vial
YES �– Syringe
Generic YES �– Vial YES �– Syringe
Tdap Adacel NO
Boostrix YES �– Syringe NO �– Vial
TriHIBit YES �– Vial
Twinrix YES �– Syringe NO �– Vial
Typhoid Typhim Vi NO Vivotif Berna N/A
Varicella (Varivax) NO Vaccinia (Smallpox) (ACAM2000) NO
Yellow Fever (YF-Vax) YES �– Vial Zoster (Shingles) (Zostavax) NO
February 2011
Appendix B
B
B-19
Appendix B
B
B-20
Appendix B
B
B-21
Aids to translating foreign immunization records.
This table lists terms for vaccine-preventable diseases and vaccines, and other terms that might be found on an immunization record, by language.
This table lists the names of specific vaccines that are used, or have been used, internationally, along with the manufacturer and country or region where the vaccine is produced or used, when known.
These tables have been adapted from (among other sources) lists developed by
the Minnesota Department of Health Immunization Program (now maintained by the Immunization Action Coalition)
and Washington State Department of Health.
See also: http://www.immunize.org/izpractices/p5120.pdf http://www.immunize.org/izpractices/p5121.pdf
These lists are not comprehensive. We have checked sources, but we cannot claim complete accuracy.
Appendix B
B
B-22
Appendix B
B
B-23
Appendix B
B
B-24
Appendix B
B
B-25
Appendix B
B
B-26
Appendix B
B
B-27
Foreign Language Terms Table 2: Product Names
Trade Name Antigen(s) Manufacturer, Country 6 in 1 Diphtheria, tetanus, pertussis, polio,
Hib, hepatitis B GSK, Ireland
A.D.T. Diphtheria, tetanus (adsorbed) Commonwealth, Australia A.K.D.S. Diphtheria, tetanus, pertussis UK ACVax Meningococcal (polysaccharide A & C) GSK, UK
ACWYVax Meningococcal (polysaccharide A, C, Y, W135) GSK, UK
Acelluvax Pertussis (acellular) Chiron, Italy ACTAcel Diphtheria, tetanus, pertussis, Hib Sanofi Pasteur, Argentina Adifteper Diphtheria, tetanus, pertussis Ism, Italy Adinvira A+B Influenza (whole virus) Imuna Adiugrip Influenza Sanofi Pasteur Admun Influenza (whole virus) Duncan Admune GP Influenza (whole virus) Duncan Agrippal Influenza Novartis AH Hepatitis B (Romania)
Aimmugen Hepatitis A (inactivated) Chemo-Sero-Therapeutic Resh Inst. Japan
Aldiana Diphtheria (adsorbed) Sevac, Czech Republic Alditeana Diphtheria, tetanus (adsorbed) Sevac, Czech Republic
Alditerpera Diphtheria, tetanus (adsorbed), pertussis Sevac, Czech Republic
Almevax Rubella Evans Alorbat Influenza (whole virus) Asta Pharma Alteana Sevac Tetanus Institute of Sera and Vaccines Amaril Yellow Fever Sanofi Pasteur, France AmBirix Hepatitis A, Hepatitis B GSK, Europe AMC Hib (polysaccharide) Cuba Anadifterall Diphtheria (adsorbed) Chiron, Italy Anatetall Tetanus (adsorbed) Chiron, Italy Anatoxal Di Te Diphtheria, tetanus Berna Biotech, Europe Anatoxal Di Te per Diphtheria, tetanus, pertussis Berna Biotech, Europe AP Polio (Romania) Arilvax Yellow fever MEDI, UK ATPA Tetanus toxoid (Romania) AVAC-1, AVA Anthrax (for U.S. military use) AVAXIM Hepatitis A Aventis Pasteur, France
Appendix B
B
B-28
Trade Name Antigen(s) Manufacturer, Country B-Hepavac II Hepatitis B Merck, Singapore Begrivac Influenza (split virus) Novartis Betagen Hepatitis B Sanofi Pasteur Biaflu Zonale Influenza (whole virus) Farmabiagini, Italy Biken-HB Hepatitis B Biken, Japan Bilive Hepatitis A/Hepatitis B (recombinant) Sinovac, China
Bimmugen Hepatitis B (recombinant, adsorbed, yeast derived)
Chemo-Sero-Therapeutic Resh Inst., Japan
Biviraten Berna Measles, mumps (live) Berna Biotech, Switzerland Buccopol Berna Polio (oral) Berna Biotech, Europe BVAC Botulinum antitoxin (for U.S. military use)
B-Vaxin Hepatitis B Laboratorios Pablo Cassara, Argentina
C.D.T. Diphtheria, tetanus (pediatric, adsorbed) Commonwealth, Australia CEF Measles (Schwarz strain) Chiron, Italy Cacar Smallpox Indonesia Campak Kerig Measles Pasteur Institute, Indonesia Celluvax Pertussis (acellular) Chiron, Italy Chiromas Influenza (same as Fluad) Novartis, Spain Cinquerix Diphtheria, tetanus, pertussis, Hib, polio GSK, Europe Cocquelucheau Pertussis (adsorbed) Sanoti Pasteur, France Cuadruple Diphtheria, tetanus, pertussis, Hib Mexico
D-Immun Diphtheria Osterreichisches Institut, Austria
D.S.D.P.T. Diphtheria, tetanus, pertussis (adsorbed) Dong Shit Pharm, Korea
D.T. Bis Rudivax Diphtheria, tetanus, rubella Sanofi Pasteur, France Di Anatoxal Diphtheria Berna Biotech, Europe Di Te Per Pol Impfstoff Diphtheria, tetanus, pertussis, polio Berna Biotech, Switzerland
Di-Te-Pol SSI Diphtheria, tetanus, polio Statens Seruminstitut, Denmark
Dif-Tet-All Diphtheria, tetanus Chiron, Italy Diftavax Diphtheria, tetanus Sanofi Pasteur Ditanrix Diphtheria, tetanus GSK, Europe DiTe Anatoxal Diphtheria, tetanus (adsorbed) Berna Biotech, Switzerland Ditoxim Diphtheria, tetanus (adsorbed) Dong Shin Pharm, Korea Double Anigen B.I. Diphtheria, tetanus Bengal Immunity Co., India DT Adulte Diphtheria, tetanus (adult) Sanofi Pasteur, France DT Bis Diphtheria, tetanus (booster) Sanofi Pasteur, France DT Coq Diphtheria, tetanus, pertussis Sanofi Pasteur, France DT Polio Diphtheria, tetanus, polio Sanofi Pasteur, France
DT TAB Diphtheria, tetanus , A & B Sanofi Pasteur, France
DT Vax Diphtheria, tetanus (pediatric) Sanofi Pasteur, France DT Wellcovax Diphtheria, tetanus (pediatric) Chiron, UK Dual Antigen Sii Diphtheria, tetanus (adsorbed) Serum Institute of India (Sii)
Appendix B
B
B-29
Trade Name Antigen(s) Manufacturer, Country Dultavax Diphtheria, tetanus, polio Aventis Pasteur, France Dupla Diphtheria, tetanus Instituto Butantan, Brazil Duplex Diphtheria, tetanus Sweden Ecolarix Measles, rubella (Schwarz & RA 27/3) GSK, Europe
Elvarix Influenza (split virus) VEB, Sachsesches Serumwerk Dresden
Encepur Tick-borne encephalitis Chiron, Europe
Enivac-HB Hepatitis B (recombinant DNA) Centro de Ingenieria Genetica Y Biotecnologia, Cuba
Enterovaccino Typhoid (IM) Isi Enzira Influenza CSL Eolarix Measles, rubella (Schwartz & RA 27/3) GSK, Europe Epaxal Berna Hepatitis A �– virosomal vaccine Berna Biotech, Switzerland Ervax Rubella (live) GSK, Mexico Ervevax RA 27/3 Rubella (live) GSK, Belgium
Esavalenti (Hexavalent) Diphtheria, tetanus, pertussis, polio, Hib, hepatitis B Italy
Euvax-B Hepatitis B (recombinant DNA) LG Chemical, South Korea Fendrix Hepatitis B (dialysis formulation) GSK, Europe Fluad Influenza (adults >65) Novartis, Europe, Asia, NZ Flubron Influenza (whole virus) Pfizer Flugen Influenza UK Fluvax Influenza CSL, Australia Fluvirine Influenza CellTech Pharma SA FOH-M Polio (inactivated) Russia FrocuoOke Polio (inactivated) Russia FSME-IMMUNE Tick-borne encephalitis Baxter, Austria FSPD Measles Russia Funed-CEME Diphtheria, tetanus, pertussis Belo Horizonte, Brazil Gen H-B-Vax Hepatitis B Merck-Behringwerke GenHevac B Pasteur Hepatitis B Sanofi Pasteur
Gene Vac-B Hepatitis B Serum Institute of India (Sii) Gripax Influenza (whole virus) Hebrew University Gripe Influenza (whole virus) Spain Gripguard Influenza (same as Fluad) Novartis, France Gripovax Influenza (whole virus) GSK Gunevax Rubella Chiron, Italy H-Adiftal Diphtheria Ism, Italy H-Adiftetal Diphtheria, tetanus Ism, Italy H-Atetal Tetanus Ism, Italy HarPaBreHnr B CtauOHAP Rubella Russia
Appendix B
B
B-30
Trade Name Antigen(s) Manufacturer, Country HAVPur Hepatitis A Chiron, Germany HB Vax Pro Hepatitis B SP HBY Hepatitis B (recombinant) KGC, Japan HDCV Human Diploid Cell Rabies Vaccine Heberbiovac HB Hepatitis B Heberbiotec, Cuba Hepabest Hepatitis A Sanofi Pasteur, Mexico Hepacare Hepatitis B (recombinant) Chiron, Europe Hepaccine-B Hepatitis B (plasma derived) Chiel Jedang, South Korea Hepagene Hepatitis B Chiron, Europe Hepativax Hepatitis B Sanofi Pasteur, Mexico Hepatyrix Hepatitis A, typhoid GSK
Hepavax-B Hepatitis B (plasma derived) Korea Green Cross, South Korea
Hepavax-Gene Hepatitis B (recombinant DNA) Korea Green Cross, South Korea
Hepcare Hepatitis B Chiron, Europe Heprecomb Hepatitis B (yeast derived) Berna Biotech, Switzerland Hevac B Hepatitis B (plasma derived) Sanofi Pasteur, France
Hexavac (Hexavax) Diphtheria, tetanus, pertussis, polio, hepatitis B, Hib
Sanofi Pasteur, Europe or Mexico
Hiberix Hib conjugate GSK HIBest Hib Sanofi Pasteur
Hinkuys karokoe Pertussis (adsorbed) Natl. Public Health Institute, Finland
HIS Influenza Serbian Institute, Yugoslavia
IBV Polio (inactivated) Statens Seruminstitut, Denmark
Immravax Measles, mumps, rubella Sanofi Pasteur, Europe Immugrip Influenza Pierre Fabre Médicament Immunil Pneumococcal (polysaccharide) Sidus Imovax Parotiditis Mumps Sanofi Pasteur, Europe Imovax Polio Polio Sanofi Pasteur, Europe Imovax Sarampion Measles Sanofi Pasteur, Europe Imovas D.T. Diphtheria, tetanus (adult) Sanofi Pasteur, Europe Imovas Gripe Influenza Sanofi Pasteur, Europe Imovax D.P.T. Diphtheria, tetanus, pertussis Sanofi Pasteur Mexico Imovax R.O.R. Measles, rubella, mumps (live) Sanofi Pasteur, Europe Imovax Rubeola Measles Sanofi Pasteur, Europe Imovax Mumps Mumps Sanofi Pasteur, Europe Imovax Oreillons Mumps Sanofi Pasteur, Europe Imovax Rage Rabies Sanofi Pasteur, Europe Imovax Tetano Tetanus Sanofi Pasteur, Europe
Infanrix Hexa Diphtheria, tetanus, pertussis, polio, Hib, hepatitis B GSK, France
Infanrix Penta Diphtheria, tetanus, pertussis, hepatitis GSK, Europe
Appendix B
B
B-31
Trade Name Antigen(s) Manufacturer, Country B, polio
Infanrix Quinta Diphtheria, tetanus, pertussis, polio, Hib GSK, Europe Infanrix Tetra Diphtheria, tetanus, pertussis, polio GSK, Europe
Inflexal Influenza Swiss Serum and Vaccine Institute
Influmix Influenza (whole virus) Schiapparelli Influpozzi Zonale Influenza (whole virus) Ivp
Influsplit SSW Influenza (split virus) VEB Sachsecsches Serumwerk Dresden
Influvac Influenza Solvay-Pharma Influvirus Influenza Ism, Italy Invirin Influenza (whole virus) GSK Ipad TP Tetanus, polio Sanofi Pasteur, France IPV-Virelon Polio (inactivated) Chiron, Europe Isiflu Zonale Influenza (whole virus) Isi, Italy Istivac Influenza Sanofi Pasteur, Europe Kaksoisrokote Dubbelvaccin Diphtheria, tetanus (pediatric) Natl. Public Health Institute,
Finland
Kikhoste-Vaksine Pertussis Statens Institutt for Folkehelse, Norway
Koplivac Measles (Edmonston strain) Philips-Duphar, Australia Kotipa Cholera, typhoid, paratyphoid Perum Bio Farma, Indonesia Krztuscowi Pertussis Poland Ksztu Pertussis Poland
Lancy Vaxina Smallpox Swiss Serum and Vaccine Institute, Switzerland
Lavantuu Tirokote Typhoid Central Pub Health La, Finland
Liomorbillo Measles Liovaxs Smallpox Chiron, Italy Lirugen Measles Sanofi Pasteur LM �– 3 RIT Measles, mumps, rubella (live) Dong Shin Pharm, Korea LM �– 2 RIT Measles, mumps (live) Dong Shin Pharm, Korea Lteanas Imuna Tetanus (adsorbed) Imuna sp., Slovakia Lyssavac N Rabies Berna Biotech, Europe M-M-Rvax Measles, mumps, rubella Chiron, Europe M-M-Vax Measles, mumps Merck, Europe M-Vac Measles (live) Serum Institute of India (Sii) Massern-Impfstoff SSW Measles (live) Chiron, Germany
Massling Measles Sweden MDPH-PA Anthrax Measavac Measles (Edmonston strain) Pfizer, UK
Mencevax A Meningococcal Group A (polysaccharide) SmithKline/RIT, Belgium
Mencevax ACWY Meningococcal quadravalent GSK
Mengivax A/C Meningococcal Groups A & C (conjugate) Sanofi Pasteur, Europe
Appendix B
B
B-32
Trade Name Antigen(s) Manufacturer, Country Meningitec Meningococcal Group C (conjugate) Wyeth, UK, Australia Meningtec Meningococcal Group C (conjugate) Wyeth, Canada Meninvact Meningococcal Group C (conjugate) Sanofi Pasteur Menjugate Meningococcal Group C (conjugate) Novartis
Menpovax 4 Meningococcal Groups A, C, Y & W135 (polysaccharide) Chiron, Europe
Menpovax A+C Meningococcal Groups A & C Chiron, Italy MeNZB Meningococcal Group B Novartus, New Zealand Mesavac Measles (Edmonston strain) Pfizer, UK Mevilin-L Measles (Schwarz strain) Chiron, UK MFV Influenza (whole virus) Servier, UK MFV-Ject Influenza (whole virus) Sanofi Pasteur, Europe Miniflu Influenza Schiapparelli, Italy Mo-Ru Viraten Measles, rubella Berna Biotech, Canada
Moniarix Pneumococcal 17-valent (polysaccharide) GSK, Europe
Monovax / Monovac BCG Sanofi Pasteur, France Mopavac Measles, mumps (live) Sevac, Czech Republic Morbilvax Measles (live) Chiron, Italy Morubel Measles, rubella (live) Chiron, Italy Moruman Berna Measles immunoglobulin Berna, Switzerland Morupar Measles, mumps, rubella (live) Chiron, Italy Movivac Measles (live) Sevac, Czech Republic Mumaten Mumps (live) Berna Biotech, Switzerland Munevan Influenza (whole virus) Medeva Mutagrip Influenza Sanofi Pasteur, Germany Nasoflu Influenza GSK, Europe Neis Vac-C Meningococcal Group C (conjugate) Baxter, Europe & Canada
Neumo Imovax Pneumococcal 23-valent (polysaccharide) Sanofi Pasteur, Mexico
Neotyf Typhoid (live, oral) Chiron, Italy Nilgrip Influenza CSL
Nivgrip Influenza (whole virus) Nicolau Institute of Virology, Romania
NorHOMHerHTA Polio (inactivated) Russia Nothav Hepatitis A Chiron, Italy
Okavax Varicella (live) Biken / Sanofi Pasteur, Japan & Europe
Optaflu Influenza (cell culture-based) Novartis, Europe, Iceland, Norway
Oral Virelon Polio (oral) Chiron, Germany Pariorix Mumps (live) GSK, Mexico & Europe Pavivac Mumps (live) Sevac, Czech Republic
Pediacel Diphtheria, tetanus, acellular pertussis, Hib, polio Europe
Penta Diphtheria, tetanus, acellular pertussis, Hib, polio Sanofi Pasteur, Europe
PENT-HIBest Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur
Appendix B
B
B-33
Trade Name Antigen(s) Manufacturer, Country Pentacel Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur, Canada Pentacoq Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur PentAct-HIB Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur, Europe Pentavac Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur
Pentavalente Diphtheria, tetanus, pertussis, hepatitis B, Hib Mexico
Pentavalenti Diphtheria, tetanus, pertussis, polio, Hib
Diphtheria, tetanus, pertussis, polio, hepatitis B
Italy
Pentaxim Diphtheria, tetanus, pertussis, polio, Hib Aventis Pasteur, France Pluserix Measles, rubella GSK, Mexico & Europe
Pneumopur Pneumococcal 23-valent (polysaccharide) Chiron, Europe
POLIAcel Diphtheria, tetanus, pertussis, polio, Hib Sanofi Pasteur, Argentina Poliomyelite Polio (inactivated) France Polioral Polio (live, oral, trivalent) Novartis Polio Sabin Polio (oral) GSK, Europe
Poloral Polio (oral) Swiss Serum and Vaccine Institute
Prevenar Pneumococcal 7-valent (conjugate) Wyeth, France Previgrip Influenza Chiron, France Primavax Diphtheria, tetanus, hepatitis B Sanofi Pasteur, Europe Priorix Measles, mumps, rubella (live) GSK, Europe & Australia Priorix-Tetra Measles, mumps, rubella, varicella (live) GSK, Europe Probivac-B Hepatitis B Probiomed, Mexico Procomvax Hib, hepatitis B Sanofi Pasteur, Europe
Pulmovax Pneumococcal 23-valent (polysaccharide) Merck
Q-Vac Diphtheria, tetanus, pertussis, hepatitis B Serum Institute of India (Sii)
Quadracel Diphtheria, tetanus, acellular pertussis, polio Sanofi Pasteur, Mexico
QUADRAcel/Hibest Diphtheria, tetanus, acellular pertussis, polio, Hib Sanofi Pasteur, Argentina
Quadravax Diphtheria, tetanus, pertussis, polio GSK Quadruple Diphtheria, tetanus, pertussis, Hib Mexico Quatro-Virelon Diphtheria, tetanus, pertussis, polio Chiron, Europe Quinivax-IN Diphtheria, tetanus, pertussis, polio, Hib Valda Laboratori, Europe Quintuple Diphtheria, tetanus, pertussis, polio, Hib GSK, Mexico
Quinvaxem Diphtheria, tetanus, pertussis, Hib, Hepatitis B Novartis/Crucell
R-HB Vaccine Hepatitis B (recombinant) Mitsubishi Chem Corp, Japan R-Vac Rubella (live) Serum Institute of India (Sii) Rabdomune Rabies Impdfstofwerke, Germany Rabipur Rabies Chiron, Germany Rabivac Rabies Chiron, Germany Rasilvax Rabies Chiron, Italy RDCV �“Rabies Diploid Cell Vaccine�”
Appendix B
B
B-34
Trade Name Antigen(s) Manufacturer, Country Refortrix Diphtheria, tetanus (adult) GSK Repevax Diphtheria, tetanus, pertussis, polio Sanofi Pasteur Revaxis Tetanus, diphtheria, polio (adult) Sanofi Pasteur (Europe) Rimevax Measles (live, Schwarz strain) GSK, Mexico & Europe Rimparix Measles, mumps (live) GSK, Europe RIT-LM-2 Measles, mumps (live) Dong Shin Pharm, Korea RIT-LM-3 Measles, mumps, rubella (live) Dong Shin Pharm, Korea
Rorvax Measles, mumps, rubella (live) Sanofi Pasteur, Europe & Brazil
Rosovax Rubella Ism, Italy Rouvax Measles (live) Sanofi Pasteur, Europe Rubavax Rubella (live) Sanofi Pasteur, UK Rubeaten Rubella (live) Berna Biotech, Europe Rubellovac Rubella (live) Chiron, Germany Rubilin Rubella (live) Chiron, UK Rudi-Rouvax Measles, rubella (live) Sanofi Pasteur, France Rudivax Rubella (live) Sanofi Pasteur, France Sahia Polio (live oral) Multiple manufacturers Sampar Plague Sanofi Pasteur, Indonesia Sandovac Influenza Sandoz, Austria Serap Diphtheria, tetanus, pertussis Perum Bio Farma, Indonesia Shanvac-B Hepatitis B Shantha, India SMBV Rabies Sanofi Pasteur, Europe Sii Rabivax Rabies Serum Institute of India (Sii) Sii Triple Antigen Diphtheria, tetanus, pertussis Serum Institute of India (Sii) Stamaril Yellow fever (live) Sanofi Pasteur, Europe
Streptopur Pneumococcal 23-valent (polysaccharide) Chiron, Europe
Subinvira Influenza (split virus) Imuna, Czech Republic Synflorix Pneumococcal (10-valent, conjugate) GSK, Europe, Australia T. Polio Tetanus, polio SP (Canada)
T.A.B. Typhoid, paratyphoid (A & B)
- Institute Pasteur, Tunisia - Egypt - Pharmaceutical Industries Corp., Burma
T-Immun Tetanus (adsorbed) Baxter, Germany T-Vaccinol Tetanus Roehm Pharma, Germany T-Wellcovax Tetanus Wellcopharm, Germany Tanrix Tetanus GSK, Europe Td-Pur Tetanus, diphtheria (adult) Chiron, Europe Td-Virelon Tetanus, diphtheria, polio Chiron, Europe Te Anatoxal Tetanus Berna Biotech, Switzerland Telvaclptap Tetanus Yugoslavia Tet-Aktiv Tetanus Tropon-Cutter, Germany Tet-Tox Tetanus CSL Limited, Australia Tetagrip Tetanus, influenza SP, France
Tetamun SSW Tetanus (fluid, nonadsorbed) Veb Sachsisches Serumwerk, Germany
Appendix B
B
B-35
Trade Name Antigen(s) Manufacturer, Country Tetamyn Tetanus Bioclon, Mexico Tetano-difter Tetanus, diphtheria Celltech Pharma
Tetanol Tetanus (adsorbed) Chiron, Sanofi Pasteur, Europe & Mexico
Tetanovac Tetanus Sanofi Pasteur, Mexico
Tetasorbat SSW Tetanus (adsorbed) Veb Sachsisches Serumwerk, Germany
Tetatox Tetanus (adsorbed) Berna Biotech, Italy Tetavax Tetanus (adsorbed) Sanofi Pasteur, Europe Tetracoq 05 Diphtheria, tetanus, pertussis, polio Sanofi Pasteur, France TetrAct-HIB Diphtheria, tetanus, pertussis, Hib Sanofi Pasteur, Europe
Tetravac Acellulaire Diphtheria, tetanus, acellular pertussis, polio Sanofi Pasteur, Europe
Tetravalenti Diphtheria, tetanus, pertussis, hepatitis B Italy
Tetraxim Tetanus, diphtheria, pertussis, polio Sanofi Pasteur, Europe Theracys BCG Aventis Pasteur, Canada Ticovac Tick-borne encephalitis Baxter SA Tifovax Typhoid (Vi polysaccharide) Sanofi Pasteur, Mexico Titifica Typhoid and paratyphoid Italy TOPV Polio (oral, trivalent) Multiple manufacturers
Trenin DPT Behring Diphtheria, tetanus, pertussis Chiron Behring GmbH, Germany
Tresivac Measles, mumps, rubella (live) Serum Institute of India (Sii)
Triacel Diphtheria, tetanus, acellular pertussis Sanofi Pasteur, Europe & Mexico
Triacelluvax Diphtheria, tetanus, acellular pertussis Chiron, Europe Trimovax Measles, mumps, rubella (live) Sanofi Pasteur, Tripacel Diphtheria, tetanus, acellular pertussis Sanofi Pasteur, Europe
Triple antigen Diphtheria, tetanus, pertussis - Chowgule & Co., India - CSL Limited, Australia
Triple Sabin Polio (live, oral) Mexico Triple Diphtheria, tetanus, pertussis Cuba, Mexico
Triple viral Measles, mumps, rubella - Mexico - Immunology Institute, Croatia
Triplice (VT) Diphtheria, tetanus, pertussis Instituto Butantan, Brazil Triplice Viral (VTV) Measles, mumps, rubella Instituto Butantan, Brazil
Triplovax Measles, mumps, rubella Sanofi Pasteur, Europe & Brazil
Tritanrix Diphtheria, tetanus, whole-cell pertussis GSK
Tritanrix-HB Diphtheria, tetanus, whole-cell pertussis, hepatitis B GSK, Mexico
Tritanrix-HB-Hib Diphtheria, tetanus, whole-cell pertussis, hepatitis B, Hib GSK
Trivacuna Leti Diphtheria, tetanus (adsorbed), pertussis Laboratory Leti, Spain
Trivax Diphtheria, tetanus (plain), pertussis Chiron, UK
Appendix B
B
B-36
Trade Name Antigen(s) Manufacturer, Country Trivax-AD Diphtheria, tetanus (adsorbed),
pertussis Chiron, UK
Trivax-Hib Diphtheria, tetanus, pertussis, Hib GSK, Europe Trivb Diphtheria, tetanus, pertussis Brazil Triviraten Measles, mumps, rubella (live) Berna Biotech, Switzerland Trivivac Measles, mumps, rubella (live) Sevac, Czech Republic Trivivax Measles, mumps, rubella Sanofi Pasteur, Mexico Tussitrupin Forte Pertussis Staatliches Institut, Germany Tuvax BCG Japan BCG Laboratory, Japan Tyne BCG Sweden Typherix Typhoid (Vi polysaccharide) GSK, Europe & Australia Typhopara-typhoidique Typhoid and paratyphoid France
Typhoral-L Typhoid (Ty21a oral) Berna Biotech, Germany Typh-Vax Typhoid CSL Limited, Australia
Va-Diftet Diphtheria, tetanus Finlay Vacunas y Sueros, Cuba
Va-Mengoc-BC Meningococcal Groups B & C Finlay Vacunas y Sueros, Cuba
Vac-DPT Diphtheria, tetanus, pertussis Bioclon, Mexico Vaccin Difteric Adsorbit Diphtheria (adsorbed) Cantacuzino Institute,
Romania Vaccin Rabique Pasteur Rabies Pasteur Vaccins
Vaccin Combinat Diftero-Tetanic Diphtheria, tetanus (adsorbed) Cantacuzino Institute,
Romania Vaccin tuberculeux attenue lyophilize BCG Sanofi Pasteur, France
Vaccinum Morbillorum Vivum Measles (live) Moscow Research Institute,
Russia Vacina Dupla Diphtheria, tetanus Instituto Butantan, Brazil Vacina Triplice Diphtheria, tetanus, pertussis Instituto Butantan, Brazil Vacina Triplice Viral Measles, mumps, rubella Brazil Vacuna Doble Tetanus, diphtheria Instituto Biologico Argentino Vacunol Tetanus Temis-Lostato, Brazil Vaksin Sampar Plague Perum Bio Farma, Indonesia Vaksin Cacar Smallpox Indonesia Vaksin Serap Diphtheria, tetanus, pertussis Perum Bio Farma, Indonesia Vaksin Campak Kerig Measles (live) Perum Bio Farma, Indonesia
Vaksin Kotipa Cholera, typhoid, paratyphoid A, B & C Perum Bio Farma, Indonesia
Vamoavax Measles, mumps (live) Institute of Immunology, Croatia
Varicella-RIT Varicella GSK, Europe
Varicellon Zaricella zoster immunoglobulin Behringwerke Aktiengesellischaft, Germany
Varie Smallpox (lyophilized) Institute of sera and Vaccine, Czech Republic
Appendix B
B
B-37
Trade Name Antigen(s) Manufacturer, Country Varilrix Varicella (live, Oka strain) GSK, Australia, New Zealand Varirix Varicella (live, Oka strain) GSK, Europe & Mexico
Vax-Tet Tetanus Finlay Vacunas & Sueros, Cuba
Vaxem-Hib Hib (polysaccharide) Chiron, Europe Vaxicoq Pertussis (adsorbed) Sanofi Pasteur, France
Vaxigrip Influenza Sanofi Pasteur, Europe & Australia
Vaxihaler-Flu Influenza (inhaler) Riker, UK Vaxipar Mumps (live) Chiron, Italy
VCDT Diphtheria, tetanus (pediatric) Cantacuzino Institute, Romania
VDA Vaccin Difteric Adsorbit Diphtheria Cantacuzino Institute,
Romania Verorab Rabies (purified vero cell) Sanofi Pasteur, France ViATIM Hepatitis A, typhoid Sanofi Pasteur, UK Vibriomune Cholera Duncan Flockhart, UK Viralinte Hepatitis B Ivax Pharmaceuticals, Mexico Virelon C Polio (inactivated) Chiron, Germany Virelon T 20 Polio (live, oral trivalent) Chiron, Germany Virivac Measles, mumps, rubella (live) Merck, Finland Virovac Massling, Perotid, Rubella Measles, mumps, rubella Sweden
Vopix Polio (oral) PT Biofarma, Indonesia V T (Vacine Triplice) Diphtheria, tetanus, pertussis Instituto Butantan, Brazil V T V (Vacina Triplice Viral) Measles, mumps, rubella Brazil
V V R Measles (live) Cantucuzino Institute, Romania
Welltrivax Trivalente Diphtheria, tetanus, pertussis Spain X-Flu Influenza CSL Zaantide Diphtheria antitoxin Imunoloski Zavod, Croatia Zaantite Tetanus antitoxin Imunoloski Zavod, Croatia Zaditeadvax Diphtheria, tetanus Imunoloski Zavod, Croatia Zaditevax Diphtheria, tetanus Imunoloski Zavod, Croatia
Zamevax A+C Meningococcal Groups A & C (polysaccharide) Imunoloski Zavod, Croatia
Zamovax Measles (live) Imunoloski Zavod, Croatia Zamruvax Measles, rubella (live) Imunoloski Zavod, Croatia Zapavax Mumps Imunoloski Zavod, Croatia Zaruvax Rubella (live) Imunoloski Zavod, Croatia
Zatetravax Diphtheria, tetanus, pertussis, parapertussis Imunoloski Zavod, Croatia
Zatevax Tetanus Imunoloski Zavod, Croatia Zatribavax Diphtheria, tetanus, pertussis Imunoloski Zavod, Croatia Zatrivax Measles, mumps, rubella (live) Imunoloski Zavod, Croatia
January 2011
Appendix B
B