introduction to methods in neuroscience

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Slides for discussion of Chapter 4 of Cognitive Neuroscience.

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Page 1: Introduction to Methods in Neuroscience
Page 2: Introduction to Methods in Neuroscience
Page 3: Introduction to Methods in Neuroscience

Figure 5.5 Metabolism of small-molecule and peptide transmitters (Part 2)

Page 4: Introduction to Methods in Neuroscience

Methodologies

Page 5: Introduction to Methods in Neuroscience

Chapter 4

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Figure 12-45b Essential Cell Biology (© Garland Science 2010)

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Microscopy

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Bright field, 400xHematoxylin stained

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Bright field, 1000xHematoxylin stained

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Fluorescence, 1000xMitoTracker Orange

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Fluorescence, 1000xActin-labeled

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Fluorescence, 400xActin-labeled + Nucleus-labeled

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Fluorescence, 1000xActin-labeled + Nucleus-labeled

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Patch Clamping

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Figure 10-35 Essential Cell Biology (© Garland Science 2010)

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Gene Knockout

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Reporter Genes

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Figure 10-29a Essential Cell Biology (© Garland Science 2010)

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Figure 10-30 Essential Cell Biology (© Garland Science 2010)

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Transgenic Animals

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Figure 10-36 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

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Figure 10-36 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)

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Figure 10-37 Essential Cell Biology (© Garland Science 2010)

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Brainbows:Transgenic Mice + Fluorescence Microscopy

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Towards Connectomics:Electron Microscopy + Human and Computer Labor

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Computed Tomography(CT or CAT Scan)

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Positron Emission Tomography(PET Scan)

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Magnetic Resonance Imaging (MRI)

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Functional Magnetic Resonance Imaging (fMRI)

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BOLD effect:Blood oxygenation level-dependent effect

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ratio of oxygenated to deoxygenated hemoglobin

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Transcranial Magnetic Stimulation (TMS)

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fMRI+TMS

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