introduction to department of biosystems science & engineering reddy.pdf · and d-bsse...
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| | Introduction and D-BSSE
Prof. Sai Reddy
2/12/2014 Sai Reddy ([email protected]) 1
Introduction to Department of Biosystems
Science & Engineering
| | Introduction and D-BSSE
ETH Zurich Department of Biosystems Science & Engineering
Assistant Professor of Biomolecular Engineering
Laboratory for Systems and Synthetic Immunology
B.S. and M.S. - Northwestern University, Evanston, USA Biomedical Engineering, 2003 and 2004
PhD – Ecole Polytechnique Federale de Lausanne, CH Bioengineering, 2008
Post-doc – University of Texas Austin, USA Chemical and Biomedical Engineering, 2008-2011
Assistant Professor – University of Colorado Boulder, USA Chemical and Biological Engineering, 2011
2/12/2014 Sai Reddy ([email protected]) 2
Sai Reddy
| | Introduction and D-BSSE 2/12/2014 Sai Reddy ([email protected]) 3
Department of Biosystems
Science & Engineering (D-BSSE)
Why is ETH Zurich in Basel?
Opportunities in Basel (Basel-area) Pharmaceutical, chemical, and modern
biotechnology industry.
>900 Life Science companies, substantial share
of world‘s industry.
1 million people – 10% Life Science experts (e.g.
EUCOR region).
Complementarity of research and education: Strong basis in biological / biomedical research
(Univ. Basel, FMI).
Bringing the engineering to Basel’s 550y
university tradition.
Decisive and continuing local support for D-
BSSE: Establishment of D-BSSE, new $215 mio
building on University campus, …
| | Introduction and D-BSSE 2/12/2014 Sai Reddy ([email protected]) 4
Mission of D-BSSE: From Systems to Synthetic
Biology
Synthetic Biology Systems Biology
Rational engineering of (complex) biological systems: Develop methods and technologies for systems analysis.
Develop ways to engineer (program or reprogram) biological systems.
| | Introduction and D-BSSE 2/12/2014 Sai Reddy ([email protected]) 5
D-BSSE Facts
Current faculty members: 15
Projected faculty: 20 by 2020
open positions available
Currently ~280 scientific staff
(bachelor, master, PhD, post-
doc) expected to grow to
400
New state-of-the-art building in
central Basel (2019)
| | Introduction and D-BSSE 2/12/2014 Sai Reddy ([email protected]) 6
Systems analysis of Synthetic Biology World-wide
Impact
Harvard
MIT
UC Berkeley
ETH (Basel) ETH (Zurich)
Oldham P, Hall S, Burton G (2012) Synthetic Biology:
Mapping the Scientific Landscape. PLoS ONE 7(4):
e34368.
| | Introduction and D-BSSE 2/12/2014 Sai Reddy ([email protected]) 7
Laboratory for Systems & Synthetic Immunology
Systems Immunology Synthetic Immunology
Our core mission is to use immunogenomics and immune cell reprogramming
for applications in biotechnology, vaccination, and cellular immunotherapy
High-throughput sequencing and bioinformatic analysis
of immune responses
Harnessing a bacterial immune response to
reprogram human immune cells
For more information:
www.bsse.ethz.ch/lssi