INTEGRATIVE NEUROLOGYYOGA AND MEDIATION’S

ROLE IN HEALTH

SHRI KANT MISHRA, ABMS, MD, MS (ADMIN. MEDICINE) (ADMIN. MEDICINE)

PROFESSOR OF NEUROLOGY /COORDINATOR PROFESSOR OF NEUROLOGY /COORDINATOR INTEGRATIVE MEDICINE INTEGRATIVE MEDICINE

KECK USC SCHOOL OF MEDICINE, LOS ANGELES, CALIFKECK USC SCHOOL OF MEDICINE, LOS ANGELES, CALIFDIRECTOR NEUROMUSCULAR PROGRAMDIRECTOR NEUROMUSCULAR PROGRAM

VA GLA AND OLIVE VIEW UCLA MEDICAL CENTERVA GLA AND OLIVE VIEW UCLA MEDICAL CENTER

HISTORICAL BACKGROUND

VARIOUS NATURAL MEDICINE REMEDIES

IN EXISTENCE SINCE THE BEGINNING OF

THE CIVILIZATION

VARIOUS ETHNIC MEDICINE HAS BEEN

PRACTICED FOR AT LEAST 2,000-5,000 YRS

LIKE CHINESE, KOREAN, AYURVEDA

(INDIAN SYSTEM OF MEDICINE) AMERICAN

INDIAN MEDICINE

HISTORICAL BACKGROUND

MANY OF THESE SYSTEMS OF MEDICINE

ARE WELL ORGANIZED WITH

RELATIVELY GOOD PHARMACOPEA BASIC

PRINCIPLES AND TRETMENT MODALITIES.

MANY MODERN MEDICINES HAVE

ORIGINATED FROM PLANT SOURCES AND

FROM ETHENIC MEDS

EXAMPLE - RESERPINE, EPHEDRINE, ETC.

FACTS AND FIGURES

CAM VISITS1993 425 MILLION VISITS (NEJM)

THIS WILL DOUBLE BY 2010. 1997 625 MILLION VISITS (JAMA)

EXPENDIETURE1997 $27 BILLION2004 $35 BILLION2010 $ DOUBLE “ David Isenberg, M.D.”

EDUCATIONAL PROGRAMS 90% MEDICAL SCHOOLS OFFER INTRODUCTORY COURSES. HARVARD,UCSF, UCLA , UCI , ETC.

RESEARCH NCCAM STARTED IN 1994 - $5 MILLION BUDGETBUDGET FY 2006 $200 MILLION

NCCAM /CLASSIFICATION

SYSTEMS OF MEDICINE

MIND BODY MEDICINE

HERBAL MEDICINE

ELECTRO MAGNETIC

MEDICINE

MANIPULATION

MASSAGE THERAPY

AROMATHERAPY

HOMEOPATHY

BIOLOGICAL BASED

MEDICINE

DIET NUTRITION

LIFE STYLE CHANGES

MIND/BODY MEDICINE TECHNIQUES INVOLVE EXPLORING THE MIND’S

ABILITY TO AFFECT THE BODY. BASED ON TRADITIONAL PRINCIPLES ON HOW THE

MIND AND BODY ARE INTERLINKED.

• YOGA• MEDITATION• MUSIC

THERAPY• PRAYER

THERAPY• PSYCHOTHERAP

Y• COUNSELING• HYNOTHERAPY • SPIRITUALITY

• ART THERAPY• BIOFEEDBACK• RELAXATION

TECHNIQUES• DANCE THERAPY• GUIDED IMAGERY• HUMOR THERAPY• SUPPORT GROUPS

CLASSIFICATION

CAM MODALITIES USED IN NEUROLOGICAL DISORDERS

AYURVEDA

YOGA

HOMEOPATHIC MEDICINE

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS)

VAGAL /TRIGEMINAL NERVE STIMULATION

CHINESE MEDICINE

ACUPUNCTURE

ACCUPRESSURE

ELECTRO

ACUPUNCTURE (EA)

CHIROPRACTIC

TRAGER THERAPY

MASSAGE THERAPY

AROMATHERAPY

HERBAL THERAPY

THE ROLE OF CAM IN NEUROLOGICAL DISORDERS

CNS DEMENTIA, INCLUDING ALZHEIMERS DISEASE PARKINSON’S DISEASE EPILEPSY STROKE HEADACHE MULTIPLE SCLEROSIS

PNS PERIPHERAL NEUROPATHY, CARPAL TUNNEL

SYNDROME CHRONIC PAIN MUSCLE DISORDERS FIBROMYALGIA

AYURVEDA

ANCIENT MEDICAL DISCIPLINE OF INDIA

LITERAL MEANING: “SCIENCE OF LIFE”

DATES BACK THOUSANDS OF YEARS COMPREHENSIVE APPROACH TO HEALING PRINCIPAL

GOAL:

PRESERVATION AND PROMOTION OF HEALTH

EMPHASIS ON ENHANCEMENT OF NATURAL IMMUNITY

BASED ON 4 ELEMENTS, 3 HUMORS AND TISSUES

INDIVIDUAL CONSTITUTIONAL PROFILE. SIMILARITIES WITH TCM

YOGA

PRACTICED IN INDIA FOR THOUSANDS OF YEARS BY FAR THE BEST KNOWN AND MOST POPULAR

EXERCISE REGIMEN. 1.69 MILLION PRACTICE IT REGULARLY. COMES FROM SANSKRIT ROOT “YUJ”

DEFINITION • TO YOKE, TO JOIN AND TO DIRECT AND CONCENTRATE

ONE’S ATTENTION. BASIC PRINCIPLES

• FOCUSES ON THE BODY’S MUSCULATURE POSTURE,

BREATHING MECHANISMS(PRANAYAMA) AND

CONSCIOUSNESS. EFFECTS ON NERVOUS SYSTEM

• REDUCTION IN CHRONIC PAIN AND BACK PAIN• CARPAL TUNNEL SYNDROME

TYPES OF YOGA

KARMA Yoga YOGA OF ACTION

BHAKTI YOGA THE PATH OF DEVOTION

RAJ YOGA THE MOST COMPREHENSIVE YOGA IT HAS 8 PARTS INCLUDING

• ASANAS• MORAL ETHICAL• PRANAYAMA• MEDITATION

PRANAYAMA

PRANAYAMAS ARE SPECIALLY DEVELOPED BREATHING TECHNIQUES.

ALSO IMPROVES BRAIN FUNCTION (INTELLIGENCE AND MEMORY) INCREASING THE ELIMINATION OF TOXINS FROM THE SYSTEM.

THE TOTAL EFFECT OF YOGA ASANAS AND BREATHING IS TO PRODUCE A STATE OF HIGH VITALITY AND REJUVENATION

STUDIES HAVE SHOWN THAT IT INCREASES THE SEROTONIN LEVEL IN THE BRAIN WITH REGULAR PRANAYAMA

MEDITATION

IT IS A SELF-DIRECTED PRACTICE FOR RELAXING THE BODY AND CALMING THE MIND.

MEDITATION IS A SAFE AND SIMPLE WAY TO BALANCE A PERSON'S PHYSICAL, EMOTIONAL, AND MENTAL STATES.

IT IS SIMPLE, BUT CAN BENEFIT EVERYONE

PROVEN SCIENTIFIC/SOCIAL STUDIES

EFFECTS CAN BE DIVIDED INTO THREE PARTS

1. HEALTH PROMOTION AND DISEASE PREVENTION

2. PHYSICAL ILLNESS

3. MENTAL ILLNESS

HEALTH PROMOTION AND DISEASE PREVENTION

EFFECTS OF YOGA

IMPROVES RESPIRATORY ENDURANCE, MUSCLE STRENGTH, AND OVERALL PHYSICAL FITNESS. GENERAL EFFECT

MEDITATION AND BREATHING EXERCISES INCREASE PHYSICAL AND MENTAL WELL BEING.

ENDOCRINE FUNCTION

BLOOD CORTISOL LEVELS LOWER AFTER MEDITATION.

CARDIOVASCULAR STRESS MANAGEMENT EFFECTS ON NERVOUS SYSTEM MUSCLE TENSION

PHYSICAL ILLNESS

EFFECTS OF YOGA NERVOUS SYSTEM

REDUCTION IN CHRONIC PAIN AND BACK PAIN. QUALITY OF LIFE IMPROVED. SEIZURE DISORDERS IMPROVE QUALITY OF LIFE AND

BETTER SEIZURE CONTROL

CARDIOVASCULAR DISEASE IMPROVES HYPERTENSION . IMPROVES HYPERCHOLESTEROLEMIA.

CANCER RHEUMATOLOGICAL DISORDERS

RESPIRATORY DISORDERS (INCLUDING ASTHMA)

MENTAL ILLNESS/ PSYCHIATRIC DISORDERS

EFFECTS OF YOGA

HELPS COGNITIVE FUNCTION IN MENTALLY RETARDED CHILDREN.

REDUCE ANXIETY LEVELS.

BIPOLAR SYNDROME IS IMPROVED.

FOUND TO BE HELPFUL IN HEROIN AND OTHER DRUG ADDICTIONS.

BENEFITS OF MEDITATION

REDUCE HEALTH CARE USE

INCREASES LONGEVITY AND QUALITY OF LIFE

REDUCES CHRONIC PAIN

REDUCES ANXIETY

REDUCES HIGH BLOOD PRESSURE

REDUCES POST-TRAUMATIC STRESS SYNDROME IN VIETNAM VETERANS

LOWERS BLOOD CORTISOL LEVELS INITIALLY BROUGHT ON BY STRESS.

STATISTICS

PHYSICIANS, PSYCHOTHERAPISTS, AND OTHER PROFESSIONALS ARE INCREASINGLY ADDING MEDITATIVE TECHNIQUES TO THEIR PRACTICE.

OVER SIX THOUSAND PHYSICIANS HAVE BEGUN THE PRACTICE OF TRANSCENDENTAL MEDITATION AND REGULARLY RECOMMEND THE TM TECHNIQUE TO THEIR PATIENTS.

MANY PHYSICIANS CONSIDER MEDITATION A KEY ELEMENT OF AN INTEGRATED HEALTH PROGRAM.

CHINESE MEDICINE

3,-4000 YEARS OLD HEALTH CARE SYSTEM

REQUIRES

BALANCE OF BODY’S DIFFERENT ENERGIES

(YIN AND YANG)

PROPER FLOW OF ENERGY

• CAN BE CORRECTED BY STIMULATING

RELATED CHANNELS BY HERBAL REMEDIES,

ACUPUNCTURE, ACUPRESSURE

HOMEOPATHIC MEDICINE

SPECIALIZED, SCIENTIFIC FIELD OF ALTERNATIVE MEDICINE

STARTED IN LATE 18TH CENTURY BY PHYSICIAN SAMUEL HAHNEMANN.

BASED ON PRINCIPAL OF SIMILARS

HIGHLY DILUTED PREPARATIONS OF SUBSTANCES

STIMULATES HEALING IN PTS WHO HAVE SIMILAR SX’S WHEN ILL

USED IN HEADACHE,DEMENTIA,CHRONIC PAIN

AROMA THERAPY

ORIGINS TRACED BACK TO ANCIENT EGYPT AND INDIA

3,000 YEARS AGO, ESSENTIAL OILS WERE UTILIZED FOR HEALING, COSMETICS, PERFUMERY, AND RELIGIOUS RITES.

BENEFITS REDUCES STRESS, ENHANCES RELAXATION,

RELIEVE ANXIETY AND OTHER EMOTIONAL DISORDERS.

ACUPUNCTURE

ACUPUNCTURE (THE USE OF NEEDLES) ELECTRO ACUPUNCTURE (EA)

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS)

ACUPRESSURE THE USE OF PRESSURE ON SPECIFIC POINTS

FIFTY-FIVE PERCENT OF CAREGIVERS REPORTED THAT THEY HAD TRIED AT LEAST ONE ALTERNATIVE THERAPY TO IMPROVE THE PATIENT'S MEMORY.

TWENTY PERCENT OF CAREGIVERS TRIED THREE OR MORE UNPROVEN THERAPIES

VITAMINS WERE USED MOST FREQUENTLY (84%) HEALTH FOODS (27%) HERBAL MEDICINES (11%)

"SMART PILLS" (9%) AND HOME REMEDIES (7%)

DEMENTIA

COLEMAN LM, FOWLER LL, WILLIAMS ME.

AM GERIATR SOC. 1995 JUL;43(7):747-50

DEMENTIA

AYURVEDIC HERBAL TREATMENTS MEDHYA(MEMORY ENHANCER)

BRAHMI (BACOPA )

SANKHPUSPI CONVOLULUS PLURICALIS

GOTUKOLA

CURCUMIN

WITHANIA SEMNIFORA ETC

DEMENTIA GINKGO CONTROVERSIAL

STUDIES SHOW: SLOWS DEVELOPMENT OF 20% OF DEMENTIA BY 6-12

MONTHS

META ANALYSIS BARRY OKEN 1998, ARCHIVES OF NEUROLOGY

OVERALL THERE WAS A SIGNIFICANT EFFECT SIZE OF 0.40 (P<.0001). THIS MODEST EFFECT SIZE TRANSLATED INTO A 3% DIFFERENCE IN THE ALZHEIMER DISEASE ASSESSMENT SCALE-COGNITIVE SUBTEST.

SOLOMON JAMA 2002 NEGATIVE STUDY: TOTAL 26 TRIAL MAJORITY OF STUDIES NEGATIVE?

MIGRAINE HEADACHE

HOMEOPATHIC TREATMENT IN A DOUBLE-BLIND, PLACEBO-CONTROLLED

TRIAL ON 60 PTS SHOWED THAT 93% OF PATIENTS GIVEN AN INDIVIDUALIZED HOMEOPATHIC MEDICINE EXPERIENCED GOOD RESULTS.

ISOMETRIC NECK EXERCISE / BIOFEEDBACK A COMBINATION PRODUCT CONTAINING MAGNESIUM, RIBOFLAVIN, AND FEVERFEW; MELETONIN, GINGER AND GINKO

TRAGER THERAPY

TREATMENT OF PATIENTS WITH CHRONIC HEADACHES IN A HOSPITAL FOR TRADITIONAL

CHINESE MEDICINE IN GERMANY

A RANDOMISED, WAITING LIST CONTROLLED TRIAL SHOWED PATIENTS WITH MIGRAINE AND A COMBINATION OF MIGRAINE AND EPISODIC TENSION-TYPE HEADACHES HAD LASTING IMPROVEMENTS MORE THAN PATIENTS WITH OTHER HEADACHES, WITH TREATMENT OF TRADITIONAL CHINESE MEDICINE IN KOTZTING

MELCHART D, HAGER S, MUNICH, GERMANY.

ACUPUNCTURE FOR PATIENTS WITH MIGRAINE

ACUPUNCTURE IS WIDELY USED TO PREVENT MIGRAINE ATTACKS.

THE PROPORTION OF RESPONDERS (REDUCTION IN HEADACHE DAYS BY AT LEAST 50%) WAS 51% IN THE ACUPUNCTURE GROUP, 53% IN THE SHAM ACUPUNCTURE GROUP, AND 15% IN THE WAITING LIST GROUP.

ACUPUNCTURE AND SHAM ACUPUNCTURE IN REDUCING MIGRAINE HEADACHES ALTHOUGH BOTH INTERVENTIONS WERE MORE EFFECTIVE IN REDUCING MIGRAINE HEADACHES THAN A WAITING LIST CONTROL.

LINDE K, STRENG A, MUNICH, GERMANY

MULTIPLE SCLEROSIS

ACUPUNCTUREMAIL SURVEY INCLUDED 217 PATIENTS

RESULT 37 HAD REDUCED PAIN 34 DECREASED SPASTICITY 14 IMPROVED BLADDER AND BOWEL

DYSFUNCTION 34 IMPROVED WALKING AND MOBILITY 48 EXPERIENCED ELEVATED ENERGY LEVEL

AND REDUCED FATIGUE YOGA AND MS >MEDITATION

AYURVEDIC HERBS IN NEURODEGENERATIVE DISEASES

AYURVEDIC PLANTS USED FOR THE MANAGEMENT OF NEURODEGENERATIVE DISEASES SUCH AS: PARKINSON'S, ALZHEIMER'S, LOSS OF

MEMORY DEGENERATION OF NERVES AND OTHER

NEURONAL DISORDERS

GENERALLY POSSESSES STRONG ANTIOXIDANT ACTIVITY.

AYURVEDA IN PARKINSON'S DISEASE. CLINICAL PROSPECTIVE STUDY, OF AYURVEDA

TREATMENT (A CONCOCTION IN COW'S MILK

OF POWDERED MUCUNA PRURIENS AND

HYOSCYAMUS RETICULATUS SEEDS WITHANIA

SOMNIFERA AND SIDA CORDIFOLIA ROOTS)

IN 18 CLINICALLY DIAGNOSED (WITH A MEAN

HOEN AND YAHR VALUE OF 2.22) PARKINSONIAN

PATIENTS SHOWED:

PARKINSON’S DISEASE

HP - 200

DERIVED FROM MUCUNA PRURIENT(AYURVEDIC HERB)

A CLINICAL TRIAL OF 60 PATIENTS SHOWED THAT HP-200 MAY HAVE SOME BENEFITS. (BALA MANYAM PI)

AYURVEDA IN PARKINSON'S DISEASE.

RESULTS SIGNIFICANT IMPROVEMENT IN ACTIVITIES

OF DAILY LIVING (ADL) AND ON MOTOR

EXAMINATION AS PER UPDRS RATING.

SYMPTOMATICALLY, THEY EXHIBITED

GOOD RESPONSE IN TREMOR,

BRADYKINESIA, STIFFNESS AND CRAMPS.

CURCUMIN AND ALZHEIMER DISEASE

CURCUMIN, IN VITRO, INCUBATED WITH ABETA 40 AND A BETA42, SIGNIFICANTLY DECREASES AMYLOID AGGREGATION (GREG COLE ET AL).

CAPABLE OF INDUCING THE DISAGGREGATION OF PRE-AGGREGATED AMYLOID.

SIGNIFICANTLY REDUCES ABETA OLIGOMERS FORMATION.

INHIBITED THE CELL TOXICITY OF AMYLOID OLIGOMERS. POSSESSES POTENT ANTI-AMYLOIDOGENIC ACTIVITY, IN

ALZHEIMER AGED APP TRANSGENIC MICE TG2576. RATIONALE FOR CURCUMIN USE IN CLINICAL TRIALS

PREVENTING OR TREATING IN AD ,WHICH IS UNDERWAY AT UCLA

EPIDEMEOLOGICAL STUDY IN INDIA GANGULI ETAL

CURCUMIN AND ALZHEIMER DISEASE

THE INHIBITION OF EGR-1 DNA-BINDING ACTIVITY BY CURCUMIN WAS DEMONSTRATED, IN VITRO, IN HUMAN THP-1 MONOCYTES AND HUMAN PERIPHERAL BLOOD MONOCYTES.

INHIBITION RESULTED IN A DECREASE IN MRNA EXPRESSION OF CYTOKINES (TNFALPHA AND IL-1BETA) AND CHEMOKINES (MCP-1, IL-8 AND MIP-1BETA).

CURCUMIN COULD THUS AMELIORATE INFLAMMATION.

CURCUMIN DID NOT AFFECT THE VIABILITY OF CELLS.

MEDITATION IN NEUROLOGICAL DISORDERS

ACCORDING TO STUDIES CONDUCTED BY HERBERT BENSON, M.D., [HARVARD MEDICAL SCHOOL]

MEDITATION PROCESS COUNTERACTED THE EFFECTS OF THE SYMPATHETIC NERVOUS SYSTEM.

WHEREAS THE SYMPATHETIC SYSTEM DILATES THE PUPILS AND GETS THE HEART RATE, RESPIRATION, AND BLOOD PRESSURE UP, THE PARASYMPATHETIC SYSTEM, ACTIVATED WHEN WE MEDITATE, DOES JUST THE OPPOSITE.

ALS AND CURCUMIN

FAMILIAL FORMS OF ALS DEMONSTRATE UP-REGULATION OF TUMOR NECROSIS FACTOR ALPHA (TNFALPHA).

CURCUMIN ANTAGONIZED TNF ALPHA, IN VITRO, IN THE MICROGLIAL CELL LINE, DERIVED FROM MOUSE WALKER EOC-20 CELLS.

ANTAGONISM WAS POSSIBLY DUE TO THE INHIBITION OF 5LOX.

CURCUMIN COULD THUS BE USED FOR CLINICAL BENEFIT IN ALS. (WEST ET AL )

EPILEPSYALTERNATIVE TREATMENTS

VAGUS NERVE STIMULATIONVAGUS NERVE STIMULATION

DEEP BRAIN STIMULATIONDEEP BRAIN STIMULATION

CORTICAL STIMULATIONCORTICAL STIMULATION

TRIGEMINAL NERVE STIMULATIONTRIGEMINAL NERVE STIMULATION

FISH OILFISH OIL

BACKGROUNDBACKGROUND THE TRIGEMINAL NERVE PROJECTS TO THE THE TRIGEMINAL NERVE PROJECTS TO THE

NUCLEUS TRACTUS SOLITARIUS (NTS), THE LOCUS NUCLEUS TRACTUS SOLITARIUS (NTS), THE LOCUS CERULEUS, AND THE VAGUS NERVE.CERULEUS, AND THE VAGUS NERVE. Stimulation of NTS reduces seizures induced by

amygdala stimulation.

STIMULATION OF LC SUPPRESSES COBALT AND STIMULATION OF LC SUPPRESSES COBALT AND PENICILLIN INDUCED EPILEPTIC DISCHARGES.PENICILLIN INDUCED EPILEPTIC DISCHARGES. Lesioning the LC blocks the effect of vagus nerve Lesioning the LC blocks the effect of vagus nerve

stimulation.stimulation.

TRIGEMINAL NERVE STIMULATION BLOCKS PTZ INDUCED SPIKES AND SEIZURES IN RATS

Fanselow, Nicolelis, et al 2000

SUDDEN DEATH IS A MAJOR PROBLEM IN

EPILEPSY SUDDEN DEATH SUDDEN DEATH

RATES ARE RATES ARE SIGNIFICANTLY SIGNIFICANTLY HIGHER IN HIGHER IN EPILEPSY THAN EPILEPSY THAN AGE MATCHED AGE MATCHED POPULATIONPOPULATION SPERLINGSPERLING ANNEGERSANNEGERS

Major Categories of Mortality in Epilepsy

Seizures20%

Sudden Death20%

Underlying Causes of Epilepsy

20%

Usual Causes:CancerHeart

DiseaseStroke

STROKE

AYURVEDIC SPICE: TURMERIC INHIBITS PLATELET AGGREGATION AND

MODULATES EICOSANOID BIOSYNTHESIS AYURVEDIC OIL MASSAGE

ACUPUNCTURE A CLINICAL TRIAL ON 118 PTS: SHORTER

DURATIONS OF HOSPITAL STAY FOR REHAB

YOGA

MASSAGE THERAPY

SUB ACUTE LOW-BACK PAIN

PROTOCOLRANDOMIZED CONTROLLED TRIAL COMPARED COMPREHENSIVE MASSAGE THERAPY(CMT) TO SOFT-TISSUE MANIPULATION (STM), REMEDIAL EXERCISE, AND PLACEBO.

RESULTS (1 MONTH FOLLOW-UP) % OF PATIENTS WHO REPORTED NO PAIN

• CMT: 63%• STM: 27%• PLACEBO: 0%

CHIROPRACTIC MANUPULATION AND ACUPUNCTURE USEFUL IN NIH CONCENSOUS PANEL REPORT

CHRONIC PAIN

TENS

STUDY OF 482 PATIENTS WITH CHRONIC PAIN OF VARIOUS ORIGINS. GOOD RESPONSE

PROBLEMS WITH STUDY INDIVIDUAL DIFFERENCES IN PTS RESPONSE HIGH DROP OUT RATE IN LONG-TERM

TREATMENT

PERIPHERAL NEUROPATHY

YOGA / CARPAL TUNNEL SYNDROMEYOGA / CARPAL TUNNEL SYNDROME

RANDOMIZED SINGLE-BLIND CONTROLLED TRIAL 42 PTS WITH CTS

RESULT: YOGA-BASED REGIMEN MORE EFFECTIVE THAN WRIST SPLINTING OR NO TX IN RELIEVING SOME S/SXS OF CTS

PHALEN SIGN IMPROVEMENT IN 12 PTS WITH YOGA TX VS. 2 PTS IN CONTROL

YOGA

YOGA'S ROLE IN THE MANAGEMENT OF DEPRESSION HAS BEEN INVESTIGATED AND REPORTED TO BE BENEFICIAL FOR COLLEGE STUDENTS WHO EXHIBIT A HIGH LEVEL OF DEPRESSIVE SYMPTOMS.

CASE REPORT DESCRIBING AN APPLICATION OF YOGA THERAPEUTICS TO A PATIENT WITH PARKINSON DISEASE.

RELAXATION MAY PROMOTE POSITIVE EFFECTS ON CAROTID ATHEROSCLEROSIS, HYPERTENSION, DIABETES, AND CORONARY ARTERY DISEASE, WHICH ARE IDENTIFIED AS RISK FACTORS ASSOCIATED WITH STROKE OCCURRENCE OR REOCCURRENCE

YOGA AND MS

DR. OKEN HYPOTHESIS: YOGA MIGHT BE BENEFICIAL IN TERMS OF

COGNITIVE FUNCTION IN MULTIPLE SCLEROSIS, WHERE THERE ARE SIGNIFICANT COGNITIVE PROBLEMS, SUCH AS DIFFICULTY CONCENTRATING.

COGNITIVE FUNCTION WAS THE PRIMARY OUTCOME MEASURE IN THE STUDY, AND ALL THE QUALITY OF LIFE MEASURES SUCH AS FATIGUE AND MOOD WERE SECONDARY OUTCOME MEASURES

FUTURE INVESTIGATIVE POTENTIALS

YOGA CAN BE USED TO PREVENT AND CURE VARIOUS INDIVIDUAL, COMMUNITY, AND SOCIETAL ILLNESSES.

INDIVIDUAL DEVELOPMENT TO UPLIFT ONESELF IS CRUCIAL AND NEEDS TO BE STUDIED.

YOGA WITH AYURVEDA AND MODERN MEDICINE CAN BE APPLIED TO AGING, DEMENTIA, STRESS ADAPTATION, G.I. DISORDERS, HIV/AIDS, AUTOIMMUNE DISORDERS, AND MANY OTHER AILMENTS.

W. SOMNIFERA IN MUSCLE SARCOPENIA

PRELIMINARY TRIAL ON 28 HEALTHY VOLUNTEERS (22 MALES) AND (6 FEMALES) BETWEEN 60 TO 75 YEARS WAS CONDUCTED.

THE HERB W. SOMNIFERA MAY HAVE THE POTENTIAL TO IMPROVE MUSCLE STRENGTH AND ENDURANCE FOR THE AGED SUBJECTS.

SHOWED POTENTIAL EFFECT IN IMPROVING MUSCLE FUNCTIONING AND MUSCLE STRENGTH TESTING

FUNCTIONAL MEASUREMENT UP AND GO TEST

NO SIDE EFFECT WAS OBSERVED FOR THE HERB AT 500 MG (BID) FOR THE AGED SUBJECTS FOR CONTINUOUS PERIOD OF 3 MONTHS. •MISHRA ETAL 2002

FIBROMYALGIA CLINICAL SURVEY SHOWS 98% PERCENT OF THE

PATIENTS USE SOME TYPE OF CAM THERAPY.

MOST FREQUENTLY USED CAM TREATMENTS: EXERCISE FOR A SPECIFIC MEDICAL PROBLEM (48%), SPIRITUAL HEALING (PRAYERS) (45%), MASSAGE THERAPY (44%), CHIROPRACTIC TREATMENTS (37%), VITAMIN C (35%), VITAMIN E (31%), MAGNESIUM (29%),

VITAMIN B COMPLEX (25%), GREEN TEA (24%), AND WEIGHT-LOSS PROGRAMS (20%). ACUPUNCTURE 20%

CONCLUSION: CAM USE IS COMMON IN PATIENTS REFERRED TO A FIBROMYALGIA TREATMENT PROGRAM.. WAHNER-ROEDLER DL, MAYO CLINIC COLLEGE OF

MEDICINE, ROCHESTER, MINN 55905, USA

FUTURE OF CAM

TM/CAM WILL UNDER GO RIGOROUS SCRUTINY AND WILL BE MORE EVIDENCE BASED

EFFICACY, QUALITY--- WILL BE INCORPORATED IN TM

SCIENTIFIC INTEGRATION OF TM/MODERN ALLOPATHIC MEDICINE

A PARADIGM SHIFT in HEALTH CARE

COST EFFECTIVE, EASILY ACCESIBLE

QUALITY HEALTH CARE WILL EVOLVE

WHO IS HELPING CAM / TM ??

SUMMARY

CAM IS CONSIDERED AS ANCIENT, TRADITIONAL HEALTHCARE DISCIPLINE PRACTICED FOR THOUSANDS OF YEARS

IN RECENT DECADES INCREASING AMOUNT OF INTEREST IN CAM IN WESTERN COUNTRIES, ESPECIALLY IN FIELD OF NEUROLOGY.

PROPER EDUCATION FOR MODERN HEALTH CARE PRACTITIONERS

INCREASING AMOUNT OF EVIDENCE-BASED RESEARCH BEING PERFORMED.

THERE IS NEED FOR FURTHER RESEARCH IN NEUROLOGICAL DISORDERS