heinz g. floss- biosynthesis of ergot alkaloids and related compounds

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874 H. G. FLOSS

Biosynthesis of ergot alkaloids and related compounds 875

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Biosynthesis of ergot alkaloids and related compounds 879

880 H. G. FLOSS

Biosynthesis of ergot alkaloids and related compounds 881

Biosynthesis of ergot alkaloids and related compound^ 887

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Biosynthesis of ergot alkaloids and related compounds 891

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Biosynthesis of ergot alkaloids and related compounds 893

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Biosynthesis of ergot alkaloids and related compounds 895

Biosynthesis of ergot alkaloids and related compounds 897

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Biosynthesis of ergot alkaloids and related compounds 901

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Biosynthesis of ergot alkaloids and related compounds1 907

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CONCLUDING REMARKS

The foregoing review has hopefully shown that thebiosynthesis of the ergoline ring system, which at onetime looked like a simple sequence of mostly non-specificreactions, involves a substantial number of very specificand rather complicated transformations. It has also

Medicinal Chemistry and Pharmacognosy, particularly ProfessorsJ. M. Cassady, C.-j. Chang, P. F. Heinstein and J. E. Robbers, andwith a number of other research groups, particularly that ofProfessor D. Groger, Halle (Saale), to all of whom I am greatlyindebted. Finally I want to thank Mrs. Lorraine Smith for herskill and patience in typing this manuscript and drawing all thestructures.

Biosynthesis of ergot alkaloids and related compounds 909

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Biosynthesis of ergot alkaloids and related compounds 911

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