fungal colonic mass : basidiobolus
DESCRIPTION
Fungal Colon mass : Basidiobolus colitisTRANSCRIPT
FROZEN STUDY
•1 st SAMPLE : INFLAMMATORY
•2nd SAMPLE : MASS OF BOGGY SOFT
TISSUE & FAT
•6cmX4cms
•FROZEN DIAGNOSIS :
•NECROTIZING FUNGAL
INFLAMMATION
DIAGNOSIS
FUNGAL INFLAMMATORY MASS :
Zygomycosisspecies Of -? Sub
** Fungal cultures are recommended for identification of exact type.
Fungal infection
•>100,000 fungal species
•Only 150 are pathogenic for humans
• -: FACTORS AFFECTING
•1)Virulence of agent
• 2) Route of infection
• 3)Dose of the agent
•4) Immunological status of host.
Broad Categories
•1. Superficial fungus
•2.Cutaneous&sub-cutaneous
•3.Systemic mycoses
•4.Infections that resemble Mycosis
Terminology
•Filament that forms the thallus or body of most : HYPHA
fungi.
•like filament produced -Short hyphal: PSEUDOHYPHAby the sucessive buds – of a yeast that elongate and fail to
separate.
•: having craoss walls.SEPATE
•’’ : HOEPPLI Material-SPLENDORE‘‘Eosinophilic substance ,surrounding some fungi, represents a
localized antigen antibody reaction in hypersensitizesd host.
Lab Diagnosis of Fungal infection
• Fungal Culture & Morphology. 1
•KOH preparation,Microscopy
• :.Immunohistology2
•DFA(direct fluorescent antibody),
•Immunohistochemical method,
•Molecular tests- DNA/RNA based(PCR).
•.Serological:3
• Latex agglutination,Complement fixation,ELISA
•.Blood Antigens:4
• Galactomannan,Glucan
Angioinvasive Fungi
•.Zygomycosi(mucormycosis)
•Aspergillus spc’s
•Systemic Phycomycetes
•Occasionally Candida albicans
SPLENDORE HOEPPLI material”“
•SC PHYCOMYCOSIS (Basidiobolus sp’s)
•SUBMUCOUS PHYCOMYCOSIS : (Entomotphthora coronata)
•ASPERGILLUS
•
•SPOROTHRIX
,6, No:39, Vol:2001Reference: Jr.Clinical microbiology, June
.GIT Basidiobolus Rt.Iliac fossa massDr Z.U.Khan, Kuwait :