fmri results

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Page 1: fMRI Results
Page 2: fMRI Results

Harnessing the power and appeal of

technology to improve kids’ health

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Page 3: fMRI Results

research! innovation! customer input!

Our Model!

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Page 4: fMRI Results

•  20 levels!•  7 cancer types!•  Objectives: kill cells, manage side-effects and complications!

• Weapons: chemo, radiation, antibiotics, stool softener!

Re-Mission!

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Page 5: fMRI Results

Warning: Playing These Video Games May Be Good for Your Health

•  Improved treatment adherence!–  16% increase in antibiotic doses!–  Blood chemo levels 20% higher!

•  Improved cancer knowledge!•  Greater self-efficacy: Increased belief in

ability to control/cope with cancer!

PEDIATRICS August 2008!

RE-MISSION WORKS!

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Page 6: fMRI Results

Knowledge and learning are only part

of the story

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Identifying the mechanisms of action in Re-Mission!

Page 7: fMRI Results

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Treatment!adherence!

Identifying the mechanisms of action in Re-Mission!

Page 8: fMRI Results

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Knowledge!

Treatment!adherence!

Emotion/!Motivation!

Re-Mission Attitudes Study!Jennifer Aaker, Ph.D., Stanford University!

Re-Mission Works – But How?

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Identifying the mechanisms of action in Re-Mission!

Page 9: fMRI Results

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How does videogame play influence real-life behavior?!

? Interactivity and Reward-Related Neural Activation During a Serious Videogame!

!!h#p://dx.plos.org/10.1371/journal.pone.0033909  

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Identifying the mechanisms of action in Re-Mission!

Page 10: fMRI Results

Rest  

Rest  

Rest  

Rest  

10 min fMRI T2*!

Play!Rest!

Rest  

Rest  

Rest  

Res

t!

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Identifying the mechanisms of action in Re-Mission!

Page 11: fMRI Results

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Interactive play! Passive exposure!

Caudate!

Thalamus!

Hippocampus!

Caudate!

Thalamus!

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Identifying the mechanisms of action in Re-Mission!

Hippocampus!

Page 12: fMRI Results

Interactivity and Reward-Related Neural Activation!

During a Serious Videogame!Brian Knutson, Ph.D., Stanford University!http://dx.plos.org/10.1371/journal.pone.0033909 !

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Results!•  Game-based interventions can be powerful tools for

activating health-supportive behaviors!•  Psychological outcomes (knowledge, self-efficacy)!•  Treatment-related behavior (chemo / antibiotic

adherence)!•  Interactive game-play has wide impact on the brain!

•  Learning / knowledge !•  Motivation / emotion!

•  Hippocampal activation may play a role in generalizing in-game experience to real-life behavior!

Implications!•  Psychological “recipe” for positive behavior change!•  Neural biomarkers for optimizing interventions !

iden%fying  mechanisms  of  ac%on  Identifying the mechanisms of action in Re-Mission!

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Page 13: fMRI Results

Thank you!