fmri results
TRANSCRIPT
Harnessing the power and appeal of
technology to improve kids’ health
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research! innovation! customer input!
Our Model!
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• 20 levels!• 7 cancer types!• Objectives: kill cells, manage side-effects and complications!
• Weapons: chemo, radiation, antibiotics, stool softener!
Re-Mission!
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Warning: Playing These Video Games May Be Good for Your Health
• Improved treatment adherence!– 16% increase in antibiotic doses!– Blood chemo levels 20% higher!
• Improved cancer knowledge!• Greater self-efficacy: Increased belief in
ability to control/cope with cancer!
PEDIATRICS August 2008!
RE-MISSION WORKS!
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Knowledge and learning are only part
of the story
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Identifying the mechanisms of action in Re-Mission!
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Treatment!adherence!
Identifying the mechanisms of action in Re-Mission!
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Knowledge!
Treatment!adherence!
Emotion/!Motivation!
Re-Mission Attitudes Study!Jennifer Aaker, Ph.D., Stanford University!
Re-Mission Works – But How?
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Identifying the mechanisms of action in Re-Mission!
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How does videogame play influence real-life behavior?!
? Interactivity and Reward-Related Neural Activation During a Serious Videogame!
!!h#p://dx.plos.org/10.1371/journal.pone.0033909
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Identifying the mechanisms of action in Re-Mission!
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10 min fMRI T2*!
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Identifying the mechanisms of action in Re-Mission!
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Interactive play! Passive exposure!
Caudate!
Thalamus!
Hippocampus!
Caudate!
Thalamus!
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Identifying the mechanisms of action in Re-Mission!
Hippocampus!
Interactivity and Reward-Related Neural Activation!
During a Serious Videogame!Brian Knutson, Ph.D., Stanford University!http://dx.plos.org/10.1371/journal.pone.0033909 !
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Results!• Game-based interventions can be powerful tools for
activating health-supportive behaviors!• Psychological outcomes (knowledge, self-efficacy)!• Treatment-related behavior (chemo / antibiotic
adherence)!• Interactive game-play has wide impact on the brain!
• Learning / knowledge !• Motivation / emotion!
• Hippocampal activation may play a role in generalizing in-game experience to real-life behavior!
Implications!• Psychological “recipe” for positive behavior change!• Neural biomarkers for optimizing interventions !
iden%fying mechanisms of ac%on Identifying the mechanisms of action in Re-Mission!
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Thank you!