fluid and electrolyte
TRANSCRIPT
Fluid and Electrolyte Management of the Surgical Patient
Jaffar AlkhuzaieM.B.B.Ch, AFRCSI, CABS
Introduction
Fluid and electrolyte management are paramount to the care of the surgical patient. Changes in both fluid volume and electrolyte composition occur preoperatively, intraoperatively, and post operatively, as well as in response to trauma and sepsis.
Case 1
40 years old maleSBONGT 1500 mlNa 150K 2.9
Total Body Water
50-60% of total body weightWho is having higher proportion of body weight as water? And Why?
Males or FemalesLean or ObeseYoung or elderly
Muscle and solid organs have higher water content than fat and boneHigher proportion of water in:
Young Lean Males
Fluid Compartments
Composition of Fluid Compartments
Classification of Body Fluid Changes
Normal Exchange of Fluid and ElectrolytesDisturbances in Fluid BalanceVolume ControlConcentration Changes
HyponatreamiaHypernatreamia
Composition ChangesHyperkalemiaHypokalemiaHypermagnesemiaHypomagnesemiaHypercalcemiaHypocalcemiaHyperphosphatemiaHypophosphatemia
Case 2
50 years old female Not know to have medical problemSBO due to adhesionsOn NGT Total intake 2700 mlTotal out put 2800 ml
Normal Exchange
Normal person consumes 2000ml of H2O75% oral intakeRest from solid foods
Daily water losses1L in Urine250 ml in stool600 insensible losses
Skin 75%Lungs 25%
Disturbances in Fluid Balance
Extracellular volume deficit: most common in surgical patients
AcuteCardiovascularCentral nervous system
ChronicDecrease skin turgorSunken eyes& CVS and CNS
Volume ExcessVolume DeficitSystem
Weight gain Peripheral edema
Weight loss Decreased skin turgor
Generalized
*Increased cardiac output *Increased central venous pressure *Distended neck veins *Murmur
*Tachycardia *Orthostasis/
hypotension *Collapsed neck veins
Cardiac
Oliguria Azotemia
Renal
Bowel edema IleusGastrointestinal
Pulmonary edema Pulmonary
Composition of Gastrointestinal SecretionsHCO 3
-
mEq/LClmEq/L
KmEq/L
NamEq/L
VolumemL/24 h
Type ofSecretion
0100-13010-3060-901000-2000Stomach30-4090-1205-10120-1402000-3000Small intestine
0403060 Colon95-11570-905-10135-145600-800Pancreas
30-4090-1105-10135-145300-800Bile
Case 3
78 years old male Not know to have any medical problemHad sigmoid colectomy for Ca2nd day post opNa 130
Hyponatremia
CausesSodium depletionSodium dilution
Sodium depletion
Decrease intakeLow Na dietEnteral feeds
Increase lossGastrointestinal Losses
VomitingProlonged NGT suctioningDiarrhea
Renal LossesDiureticsPrimary renal disease
Depletional hyponatreamia is often accompanied by extracellulr volume deficit
Sodium dilution
Due to excess extracellular waterIntentional: excessive oral intakeIatrogenic: Intravenous
Increase ADHIncrease reabsorption of water from the kidneys
DrugsAntipsychoticsTricyclic antidepressantsAngiotensin-converting enzyme inhibitors
Physical signs: usually absent Lap: hemodilution
HyperosmolarMannitolHyperglycemia
PseudohyponatremiaPlasma lipidsPlasma proteins
HyponatremiaBody System
Headache, confusion, hyper- or hypoactive deep tendon reflexes, seizures, coma, increased intracranial pressure
Central nervous system
Weakness, fatigue, muscle cramps/twitchingMusculoskeletal
Anorexia, nausea, vomiting, watery diarrheaGastrointestinal
Hypertension and bradycardia if significant increases in intracranial pressure
Cardiovascular
Lacrimation, salivationTissue
OliguriaRenal
Management of Hyponatremia
Exclude Hyperosmolar causesDepletion versus dilutionDehydration or over hydrated Normal volume >>evaluate ADHNa losses
Urine Na <20 mEq/L = extrarenalUrine Na >20 mEq/L = Renal
Free water restrictionIf sever administration NaIf neuralgic symptoms are present
3% N.SNo more than 1 mEq/L per hourUntill reaches 130 mEq/L or neurological symptoms improve
If asymptomatic 0.5 mEq/L per hour maximum 12 mEq/L per day
Hypernatremia
Loss of free waterGain sodium in excess
HypernatremiaBody System
Restlessness, lethargy, ataxia, irritability, tonic spasms, delirium, seizures, coma
Central nervous system
WeaknessMusculoskeletal
Tachycardia, hypotension, syncopeCardiovascular
Dry sticky mucous membranes, red swollen tongue, decreased saliva and tears
Tissue
OliguriaRenal
FeverMetabolic
TreatmentIn hypovolemic patients, volume should be restored.Water deficit is replaced using a hypotonic fluid
Water deficit (L)=(serum sodium -140 /140) * TBWTBW = 50% for lean men and 40% for women
No more than 1 mEq/h and 12 mEq/d for acute.
Case 4
40 years old male Polytrauma# Rt femur and blunt abdominal injuryK 2.9
OliguriaAnd on going blood transfusion
Case 5
40 year old male Case of crohns with entero-cutenousfistulaOn TPNK 6.5
Potassium
Average intake of potassium 50-100 mEq/d2% of totall body potassium is located within extracellular compartmentNormal range 3.5-5.0 mEq/L
Hyperkalemia
Excessive potassium intakeOralIntravenousBlood transfusions
Increased release of potassium from cellsHemolysisRhabdomolysisCrush injuriesGastrointestinal hemorrhageAcidosisRapid increase of extracellular osmolality
Impaired excretion by the kidneys Potassium sparing diureticsAngiotensin-Converting enzyme inhibitorsNonsteroidal antiinflammatoriesRenal insufficiency and renal failure
Symptoms Gastrointestinal
NauseaVomitingIntestinal colicDiarrhea
NeuromuscularWeaknessAscending paralysis to respiratory failure
CardiovascularECG changes
Peaked T wavesFlattened P waveProlonged PR intervalWidened QRS complexVentricular fibrillation
Cardiac arrhythmiasArrest
Discontinue exogenous potassiumCation-exchange resin, KayexalateGlucoseInsulinCalcium chloride or calcium gluconateAll the above measures are temporary lasting from 1 to 4 hoursDialysis should be considered
HypokalemiaMore common in surgical patientInadequate intake
DietaryPotassium free IV fluids Total parenteral nutrition with inadequate potassium replacement
Excessive renal excretionHyperaldosteronismMedications
Loss in gastrointestinal secreationsVomitingHigh NGT output
Intracellular shift Metabolic alkalosisInsulin therapy
Drugs induce magnesium depletionAmphotericinAminoglycosidesFoscarnetCisplatinifosfamide
SymptomsGastrointestinal
ileusConstipation
NeuromuscularWeaknessFatigueDiminished tendon reflexes Paralysis
CardiacCardiac arrestECG changes
U wavesT wave flatteningST segment changesArrhythmias
Potassium repletionOrally or intravenousIn IV no more than 10 to 20 mEq/h40 mEq/h when ECG monitoringCaution with oliguria or impaired renal function