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Cybernetic Heart Concept Innovative technology has lead to the creation of this ultra-small medical device: Scientists say this, technique could lead to a new era in ‘electronic medicine’ By Doc. G Medsys Research Consultant Innovative medical research into Bioengineering Heart plantation Evolution Health November 2014

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  1. 1. Cybernetic Heart Concept Innovative technology has lead to the creation of this ultra-small medical device: Scientists say this, technique could lead to a new era in electronic medicine By Doc. G Medsys Research Consultant Innovative medical research into Bioengineering Heart plantation Evolution Health November 2014
  2. 2. Design Concept This innovative heart implant concept, was not designed to extend the normal life cycle, but to transform the lives of thousands of patients whose only hope has been a transplantation. The main objective was to design a small intrusive heart implant, that could be placed in position without the need for intrusive open-heart surgery. This device will be inserted via a small opening in the groin or chest, a catheter is inserted, then skillfully maneuvered through blood vessels into the heart left ventricle. This standalone device requires, no external support equipment attached around the patients waist. It takeover 60% of the patients heart functions. The device will incorporates sophisticated software, that uses controls settings, allowing it to adapt to the patients lifestyle. In the US and UK alone, there are 122,796 people waiting for a heart transplantation. The lack of available donor organs is also contributing to the delaying in heart transplantation. This tiny fourth generation device could reduce waiting times, and transforms patients lives.
  3. 3. Reducing waiting times for lifesaving heart transplantation Transplant Trends in US & UK In the US 123,393 people, need a lifesaving organ transplant? (Total waiting list candidates.) Of those 78,602 people are on the active waiting list. In the US 2,577 People receiving heart transplants. Whereas the number of donors is only 1,257, so the gap continues to widen. In the UK, 261 people are on the waiting lists for heart transplants. The UK performs 195 heart transplants last year. Whilst 35 people die waiting for a heart organ transplant. Why do patients needed wait? The length time patients needs wait is influenced by the body mess index (BMI), blood group, and primary diagnosis. For example: patient over 81 kg (BMI 28.7) waited an average of 271 days to get a transplant, compared with those under 70 kg (BMI 24.6) who waited 95 days. Blood groups AB, have twice the chance of transplant compared with group 0 patients; they waited an average of 93,97 and 230 days, respectively. The lack of available donor organs is also contributing to the delaying in heart transplantation. Waiting times Stress The waiting time causes physical stress for a patient, also causes unnecessary strain on the Next of Kin; and their always-high risk of some patients has another cardiac arrest. Heart transplant costs US Breakdown of costs of single heart transplant: Donor Heart $90,000, Evaluation fees $23,000, Doctor & Nursing salaries $40,000, Hospital Care $383,000, Post-operative care $93,000, Immunosuppressive, prescription medication $25,000. Total cost per transplantation; $650,000.
  4. 4. Reducing waiting times for lifesaving heart transplantation Benefits: Using the Cybernetic Heart implant option would be considerable cut costs. As the insertion procedure is less intrusive, with no need for open-heart surgery. Hospital care costs, doctor and nursing salaries, and prescription medication would be noticeably cheaper. Quickly reduce the number of patients waiting for heart organ transplantation. Reduces the gap between available donor organ and organ available for heart transplants. Using the Cybernetic heart option will reduce time consuming to search for suitable donors heart organ. The ability to provide patients with an alternative; instead of wait months for donor heart. Whilst utilizing the Cybernetic heart option the waiting-time would be reduced to weeks. As the procedure is less intrusive, patients physical stress levels are eases, which reduces the recovery process. Thus allowing them to moved from hospital to the comfort of home convalescence. This reduces time spent occupying hospital beds and associated medical resources. Continuous medication for organ tissues rejection is know longer required, whereby making further reductions in hospital costs. Some Restraints Patients must meet certain criteria: The size of the patients left Ventricle Cavity (cavitas ventriculi sinistri) must have fully developed. Otherwise there will be insufficient maneuverability for Cybernetic Heart to be successfully implanted. Older patients with a condition known as aortic stenosis are too sick to withstand this procedure.
  5. 5. Cybernetic heart Concept Fifth Generation Device
  6. 6. Blades attached to Aortic Valve heart beat 1.07 0.1-0.2 delay Single beat of blood flow This research is investigate innovative bioengineering technics to control brain messages from the brain nervous system to the (1) Sinoatrial & (2) Atrioventricular nodes. The objective is to design an intelligent algorithm that can activate the SN & AN nodes to provide an electric pluses at will drive the rotation of the blades to get a normal heart beat-to-beat and plus. Input nervous system output Sinoatrial & Atrioventricular nodes Left Ventricle (cavity) Make outer cover flexible enough to bend here Blood input Blades rotate 1.07 per second anticlockwise -80 -70 -60 -50 -40 -30 -20 -10 0 0 2 4 6 8 10 12 Blade pitch Blade pitch Blood pressure drops to allow aortic valve to close Pressure pushes Blood into the aorta via aortic valve Impeller starts Pressure for the next heart beat
  7. 7. Cardiac Conduction System Neurons firing off in real-time Dorsal motor Nucleus of Vagus Relays information to SN & AN Nodes The cardiac conduction system is a group of specialized cardiac muscle cells in the walls of the heart that send signals to the heart muscle causing it to contract. The main components of the cardiac conduction system are the SA node, AV node, bundle of His, bundle branches, and Purkinje fibers. The SA node (anatomical pacemaker) starts the sequence by causing the atrial muscles to contract. From there, the signal travels to the AV node, through the bundle of His, down the bundle branches, and through the Purkinje fibers, causing the ventricles to contract. This signal creates an electrical current that can be seen on a graph called an Electrocardiogram (EKG or ECG). Doctors use an EKG to monitor the cardiac conduction systems electrical activity in the heart. The different colors represent the different frequencies of electrical energy in the brain as well as the paths by which that energy moves.
  8. 8. Sinoatrial Node Human Brain Nucleus Cybernetic heart program uses the generic code to controls the SN & AN nodes to activate both atrial and ventricular chambers of the patient heart. Note: From this basic ventricular on demand pacing mode is VVI or with automatic rate adjustment for exercise VVIR. -this mode is suitable when no synchronization with the atrial beat is required, as in atrial fibrillation. Atrial beat is normal delay (0.1-0.2 seconds) trigger a ventricular beat, unless it has already happed. DDDR mode covers all the options through the Cybernetic heart, this require separate atrial and ventricular leads & more complex, requiring careful programing of their functions for optimal results. Dorsal motor Nucleus of Vagus Relays information to SN & AN Nodes NASPE/BPEG Generic code for antibradycardia pacing 1 2 3 4 5 Chambers Paced Chambers Sensed Response to sensing Rate Modulation Multisite Pacing 0 = None 0 = None 0 = None 0 = None 0 = None A = Atrium A = Atrium T =Triggered R = Rate Modulation A = Atrium V = Ventricle V = Ventricle I = Inhibited V = Ventricle D = Dual (A+V) D = Dual (A+V) D = Dual (T+I) D + Dual (A+V) Atrioventricular Node Cybernetic heart motor is programed to rotate the blades at: 1.07 per second, anticlockwise then delay for 0.1-0.2. seconds. This allows the blood pressure drop and Aortic Valve to close.
  9. 9. Hearts intelligence system Energy & communications system Microprocessor Controls all the functions of the Cybernetic heart: Pumps rotation impellers, blood pressure, heart rhythms, pre-hypertension alarms, energy cells perpetual motion & storage cycles. remote diagnostics, rapid response malfunction reporting to the cardiac unit. Updating the implant system software remotely from cardiac unit. Testing system software for any security issues. Develops complex graphical images from the history data stored within the data base: blood pressure, Beat-to-beat heart rhythms any alarms warning. Energy cells Power supply source & renewable energy storage via perpetual motion provided from rotation impeller blades into energy cells for storage. Power required 24/7. Data Base Stores all historical records of the Cybernetic heart performance or any malfunctions throughout its implanted life cycle. Bluetooth Sends and receives data from the software management system and data base, to the communication implanted inserted under the skin in the patients arm. Liquid helium: contained within sealed ring Cools down the energy cells, microprocessor, Cybernetic heart system, data base processor, & Bluetooth. Cather Cather
  10. 10. Each joint moves 5% allowing the cardiologist to twist and turn the implant through blood vessels in the heart. Movability The Cybernetic heart is inserted via the patients groin and maneuver by the surgical cardiologe team into the patients left ventricle. The outer skin is covered in a layer of metal tantalum which is highly corrosion- resistant. Kevlar is used to reinforce inner surface of the Cybernetic heart, which in cooperates both strength and flexibility. Once the Cybernetic heart is in position attached to the aortic valve small magnets situated in each joint are activated. The magnet field snaps and click each joint render them immovable To ease the movability five flexible joints have been designed to ease the movability from the groin to the left ventricle. A single thickness of Bovine Pericardia tissue is used to cover the inside walls, to stop an contamination of the patients blood. Cather head is used to guild the Cybernetic heart from the patients groin into the left ventricle. Joint moves 5%
  11. 11. Cybernetic Heart delivery system Flexible delivery Cather is Inserted into a small opening in the groin Route of Cather It is inserted through a vein via an small incision in the groin, leaving no scars, and manipulated into the patients Heart left ventricle. Its anchor in place by an aortic value which compresses the patients value and replace it. Note: Older patients with a condition know as aortic stenosis, are to sick to withstand replacement of a diseased aortic value. Therefore this procedure would not be recommended. This innovation will help eliminate complications caused by traditional organ transplantation, Aside from being an easier procedure, their no need search organ tissue match. This procedure reduces the need for intrusive open-heart surgery, decreases bruising to the heart organ, stopping infections and clots. Its anchor in place using a Valve in Valve procedure. A Sapien Valve (Edwards) aortic value which compresses the patients value and replace it. Perimount Bovine Valve Valve is Compressed to maneuvered into place. Each joint moves 5% allowing the cardiologist to twist and turn the implant through blood vessels in the heart. Kevla r Pericardia Tissue
  12. 12. Wireless mobile 5G SIM card has an unique security authentication for each patient and ciphering information related to the patient heart implant. This information is access by the cardiac monitoring unit via patient identification code in order to unlock the PIN. Bluetooth is a Wireless technology for exchanging data over short distances (using short-wavelength radio waves in the ISM band from 2.4 to 2.485 GHz[2]). It transmitters data from the heart device to the arm capsule implant, overcoming problems of synchronization. Cybernetic Heart monitoring & diverter system Software Mgr. Sys Data Base Energy Cell Bluetooth Hearts intelligence system Operating System Motor System Capsule inserted into patients arm
  13. 13. Downloads patients historic device records to GP surgery for analysis. On Call Cardiology 24/7 monitoring Unit. General practitioner surgery Blood LevelsDIVERTER inserted under the skin of the patients arm Far Field Near field Monitor in real-time: Energy cells status heath status Blood pressure levels stability Patients rhythmic pulse CHECK blades rotation is function correctly heart rhythm strength of Bluetooth signal Duel SIM procedure Emergency alarm system Recharged energy cell wirelessly as required On-Call Monitoring Services Cybernetic Heart diagnostic system accesses data from the implant which transmits data to the cardiac monitoring unit. Cardiac unit receives any alarms from the implant and they can update the heart rhythm via the communication implant. Energy cell Software Mgr. Data Base Bluetooth Wireless Local GP get patients briefing notes on their smartphone iPad or PC using a App provided by cardiac monitoring unit.. 5G technology will allow a patient history file of 800mb to download in one second.
  14. 14. Cybernetic Heart system The rotating impellers drag oxygenated blood from the right ventricle into the interior blades of the Cybernetic Heart Impellers pitch is designed to push the blood up into the aortic valve at a normal beat-to-beat heart rhythm Programmable Motor System & drive shift Microprocessor & Heart management & remote diagnostics patients systems Data Base: Stores all historical records of the Cybernetic heart performance or any malfunctions throughout its implanted life cycle. Renewable energy cells power cells storage system Bluetooth: Sends and receives data from the software management system and data base, to the communication implanted inserted under the skin in the patients arm.
  15. 15. Cybernetic Heart system The rotating impellers drag oxygenated blood from the right ventricle into the interior blades of the Cybernetic Heart Impellers pitch is designed to push the blood up into the aortic valve at a normal beat-to-beat heart rhythm Microprocessor & Heart management & remote diagnostics patients systems Data Base: Stores all historical records of the Cybernetic heart performance or any malfunctions throughout its implanted life cycle. Renewable energy cells power cells storage system Bluetooth: Sends and receives data from the software management system and data base, to the communication implanted inserted under the skin in the patients arm. Programmable Motor System & drive shift
  16. 16. Cybernetic Heart implanted into the left ventricle This is an innovative heart implant concept, designed to assist patients with a life expectancy which is threatened, due to lack of available donor Hearts. The main objective was to design a small intrusive device, without the need for open-heart surgery Cybernetic heart implant
  17. 17. Cybernetic Heart implanted into the left ventricle This is an innovative heart implant concept, designed to assist patients with a life expectancy which is threatened, due to lack of available donor Hearts. The main objective was to design a small intrusive device, without the need for open-heart surgery This device will be inserted via a small opening in the groin or chest, a catheter is inserted, then skillfully maneuvered through blood vessels into the heart left ventricle. This standalone device can takeover 60% of the patients heart functions, without requiring auxiliary support equipment. The patients malfunctioning heart will be place into hibernation, and given time to recuperate. Cybernetic heart implant
  18. 18. Heart implantation alternative benefits Searching for suitable donors heart organ isnt necessary. Quickly reduce the number of patients waiting for heart organ transplantation. Incision opening of the chest is a thing of the past. No intrusive open-heart surgery is needed for this implant procedure. This intrusive procedure will speed up the patient recuperation. No continuous medication for organ rejection is required. Increase younger patients Life Expectancy. Research has lead to the creation of this ultra-small medical device: My peers say this, technique could lead to a new era in electronic medicine Note: The objective is to give; Patients a Better Quality of Life
  19. 19. The Bibliography First reference. Stanford University: A mm-Sized wirelessly power & remotely controlled locomotive implant paper written by Ada Poon. Pro. Additional references. Imperial collage London: They designed a device to read the chemical signature of appetite in the vagus nerve. The work is being led by Prof Chris Toumazou and Prof Sir Stephen Bloom. New York-Presbyterian/Columbia University Medical Center, & The Cleveland Clinic Foundation, Cleveland, Ohio. Sapien valve that utilizes Retro-Flex transfemoral delivery system, designed by Edwards. University of Louisville and the University of California, team have been pioneering electrical stimulation of the spinal cord below the injury. Paper written by: Dr. Claudia Angeli. Stanford University developed a ultra-small power source, known as 'electroceuticals, this device be an alternative for drugs, such as those affecting specific regions of the brain. Paper written by Dr. Ada Poon. University of Michigans computer science, Professor David Blaauw, developed the M^3 is a computer smaller than a grain of rice. Despite its small size, the gizmo. The Michigan Micro Mote contains solar cells that power the battery with ambient light, including indoor rooms with no natural sunlight, allowing the computers to run perpetually. University of Tokyo: Professor Akira Furusawa is the latest achievement enables us to perform the perfect quantum teleportation with a photonic chip. The next step is to integrate whole the system of quantum teleportation.
  20. 20. I am appreciative to you for your indulgence. Get more facts about is Cybernetic Heart implant; connect Doc. G. e-mail: doc [email protected]