SURGERY 20th NOVEMBER 2012

Q. Which neurocyte play an important role in blood brain barrier a) Astrocyte b)Ependmyls c) Microglia d) Oligodenroglia e) Macroglia 2. Q.. I respiratory tract exchange of gasses occur at a) respiratory bronchioles b) Alveolar duct c) alveoli d) alveolar Sac e) alveolar duct 3. Q..At the time of Ovulation a) increase body temprature b) corpus luteum form on the ovary c) increase estrogen d) increase progestron 4. Q.. In the first step of thyroid harmone synthesis iodine attach with a) Albumin b) thyroxin c) thyroglobulin d) hb 5. Q.. Antibodies formed in a) Thymus b) Plasma cells c) Lymphocytes d) Spleen e) liver 6. Q.. A man lying naked at operation table with room temprature 21.5 C” and 80% humidity by which mechanism heat transfer from body a) By Veporization b) Radiation and conduction (ans) c) sweating d) respiration e) urine 7. Q..what is the best way of communication between a patient and doctor a) A clean room b) Active Listening (ans) c ) speak Loudly d) well furnished clinic 8. Q.. A man is diagnosed by a fatal illness which has v poor prognosis as a doctor what will u do a) Hide every thing b) tell the nature of illness to patient’s family only c) tell the nature of illness to patient and his family only d) tell the nature of illness only to the patient e) Give crispy and evidence based whole information of the illness to patient (ans) 9. Q.. features distinguishing between benign from maliganant tumor is

a)metastasis (ans) b)invasive n infiltrative margins c)analpsia d) Metaplasia e) Hyperplasia 10. Q..Child with skin itching..stool examination reveal worms.. presence of which cell will aid in diagnosis a)basophils b)eosinophils (ans) c)lymphocytes d) Granulocyte e) Neutrophil 11. Q)which carcinoma do not SPREAD to bones a) thyroid medullary carcinoma b)breast c)prostate d) lung e) Liver (ans) 12. Q..A patient receives radiotherapy for Squamous Cell Carcinoma, some time later the there is scarring & ulceration to the skin because of: a- Damage to the squamous epithelium b- Endarteritis obliterans c- infection d- venous thrombosis e. 13. Q..A tumor with all germ layer involved: a) Teratoma (ans) b) Adenocarcinoma c) Hamartoma d) Sarcoma e) Seminoma 14.Q..The most significant agent in causing Cerebral Malaria: a)P.vivax b)P.Falciparum (ans) c)P.malarae d)P.Ovale e)P.Vivax + P. Ovale 15.Q.The vibration produced in intraventricular septum during rapid filling of the ventricle is the: a)1st Heart sound b)2nd Heart Sound c)3rd Heart Sound (ans) d)Murmur e)4th heart sound 16.Q..Patient with terminal ileum resection will have: a- loss of bile salts (ans) b- large volumes of water in stool c- decrease absorption of aminoacids d-Decrease absorption of Protien e) Iron deficiency 17.Q.. Which of these are Permanent Cells

a- Myocardial Cells (ans) b- glial cells c- hepatocytes d) lymphocytes e) Osteocytes 18.Q.Athlete is unable to rotate his foot medially bt turns easily laterally.cause is damage to... a.ext haluucis longus nd flexr hallucis longus b.tibialis anterior nd hallucis longus c.tibialis posterior nd extnsr hallucis longus d.tibialis ant nd flexr hallucis longus 19.Q..In which hemolytic amenia splenectomy is the treatment a) autoimmune hemolytic anemia b) G6PD deficiency c) heridatory Sephirocytosis d) Sickle cell anemia 20.Q..cardiac muscle cannot be tetanized because it has a) action potential with plateau b) gap junctions C) long duration of contraction d) long refractory period e) automaticity 21.Q..A patient with a lesion in the nose,granulomas n proteinuria with vasculitis histology show nacrosis,most likely lesion? A) Wegner's granulomatosis B) leprosy c)

sarcoidosis D ) TB 22.Q. To calculate plasma Osmolarity Na is multiply by 2 for what a)Anoins b) Other Catoins c)Protiens d) Glucose e) Aminoacid 23.Q..Morphine causes ? A) bradypnea & miosis B) bradypnea & mydriasis C) tachypnea & miosis D) tachypnea & mydriasis 24.Q.Which of the following bone is first to ossify ? A) sternum B) clavicle C) humerus D) femur 25.Q. Anterior fontanela close at ? A) 6 - 12 months B) 12- 18 months C) 18- 24 months

D) 24- 30 months 26.which of the following is not in ant. relation to left kidney a) diaphram b) pancreas c) stomach d) spleen e) Splenic flacture of colon 27..Q.Cyclic Amp represents ? A) protein pump B) Ion channels C) receptors D) hormone 28.Q. LIver held in its position with ant. Abdominal wall By? A) diaphgram B) peritoneal ligaments C) inferior vena ceva D) Hepatic Vien 29.Q.Cause of right shift of oxygen dissociation curve ? A) carbon monooxide B) fetal hemoglobin C) decrease PH D) increase PH 30.Q. Which componant of food has highest caloric value ? A) carbohydrates B) protiens C) fats D) starch 31.Q. Specificity of a test represants ? A) true positive B) true negative C) false positive D) false negative 32.Q..A 80 yr old male comes to surgical OPD ,with complaint of watery discharge coming out from umbilicus ,he has a prostatic enlargement for the last 5 yrs ,what is the cause ? A) prostatic cancer B) patent vitelointestinal duct C) patent urachus D) constriction of uretheric sphnicter E) constriction of ureter 33.Q..Post operative Pyrexia may occur secondary to: (A): Subphrenic Abscesss (B): Deep Vein Thrombosis (C): Urinary Tract Infection (D): Atelactasis (E): Blood Transfusion 34.Q..Aneamic pt ,hb 6.0, increased PLT count & hyperplastic bone marrow .Cause ? a) acute blood loss b) hemolytic anemia

c) iron deficeincy d) leukemia 35.Q..In anterior Duodenal perforation , the contents will go to a) Right iliac fossa b)Left Iliac fossa c)Anterior subhepatic space d)posterior subhepatic space e) small bursae 36.Q..pt can survive without mechanical ventilation if the lesion is at: a) Above C 2 B at C 3 C) at C4 D) Below C 5 37.Q..60 year old man has bilaterall enlarged lymph node in neck. biopsy revealed hodgkin lymphoma. which type of hodgkin has good prognosis? a) lymphocytes deplited B) lymphocyte predominant C) nodular sclerosis D) mixed cellularity 38.Q..old pt admitted in ICU with CVP passed in subclavian, developed fever. for that one blood cs sent from periphery and second in cvp tip for cs. after 2 days initial report came positive for gram +ve cocci in cvp. which antibiotic would b best for this pt. a) imepenem b) penicillin with culvanic c) vacomycin d) cefelosporins 39.Q..increased parasympathetic stimulation wiil cause relaxation of a.gut walls b.brochial smooth msc c.GIT shincters d.urinary bladder msc e.pupillary shincter 40.Q.the fibrous pericardium and serous pericardium receives innervation from a)vagus nerve b)phrenic nerve C).intercostal nerves d) Long Thoraxic nerve 41.Q.Posterior relation of Arch of Aorta? brachiocephalic vein sup vena cava right phrenic nerve left phrenic nerve pulm artery 42.Q..leison of pyramid at medulla cause . Balancing .motor loss .propeception . Discrimination loss 43.Q.secondery transport a. urea b. protien

c. amino acid d. glucose 44.Q..Disinfectant use for surgical scrub and plan is a. cholhexidine b.alcohol C. spirit d) 45.Q.Gall bladder epithelium is a) Pseudostratified columner epithilia b) Simple saquamos c) Simple columner d) Simple Cuboidal 46.Q. bleeding disorder associated with deficiency of factor VIII, and absolute F vIII is not availibe what will u give a. platelet transfusion b.cryoprecipitate c.fresh whole blood transfusion d.Albumine 47.Q.thymus a. contains lymphos b. regresses soon after birth c. forms from 4th pouch d. drive from pretracheal fascia 48.Q. Triglycerides a. transported by lipoproteins b. 3 fatty acids having glucose 49.Q.

Which type of joint is Pubic Symphysis 1. Sydesmosis 2. Fibrocartilagenous 3. diarthrosi 4. ? 5. ? 50.Q.First bone to ossify in embryo is 1. clavicle 2. femur 3. Sternum 4. Humerus 5. Tibia 51Q.What is correct regarding surfactant 1. Highest concentration in amniotic fluid is in last trimester 2. It decreases lung compliance 3. It forms a layer between maccro molecules 4. it is produced by Type 1 pneumocytes in the last trimester of pregnancy 52.Q. Its production decreases as the size of alveoli decreasesprostacyclin is produced by 1. Peyer patches 2. Mast Cells 3. Fibroblasts 4. Endothelial Cells 5. Platelets 53.Q.Which activates thirst center

1. ADH 2. Aldosterone 3. Renin 4. Angiotensin 5. ANP 54.Q. Heparin is produced by 1. Plasma Cells 2. Basophils 3. Mast Cells 4. Mesenchymal Cells 5. Fibroblasts 55.Q.Which one of the following is the pre cursor of malignancy 1. Barret Oesophagus 2. Duodenal Ulcer 3. Gastirc Ulcer 4. Angiodysplasia 5. Haemmorhoids 56.Q.In ECG what represents a T wave. 1. refractory period 2. ventricular re polarization 3. atrial systole 4. Ventricle diastole 5. Atrial re polarization 57.Q. A new borne presented with tachypnea O/E there is decrease breath sound on left side normal breath on right side, chest x ray show gut loops in left side of the pleural cavity what is the likely cause? a) defective pleuropericardial membrane b) atresia of lower esopahagus c) defective pleuroperitoneal membrane d) Hitus hernia e) Dextrocardia 58.Q.A patient with tumor in the Right Superior bronchus which segment is likely to be collapsed: a- Apical Superior b- Apical Basal c- Superior Basal d- Left apical lobe 59.Q.Pt presented with severe burns ,and comes few days later with Infection and blood diathesis, brusis on the body and died What was cause of death: a- Liver failure due to septecimia b- DIC c-Dehydration d-Renal Failure e- 60.Q.a soldier from balochistan with fever since 3 months and hepatsplenomegaly gives h/o of sleeping on ground and often biten by flies a kala azar b fliariasis c malaria d. Schistosomias 61.Q. Child with vomitting, yellow discolaration of sclera,dark coloured urine. Most appropriate investigation

will be ... a)hep A n B Serology b)serum bilirubin n ALT c)Alkaline phosphatase d)Total bilirubin 62.Q. CSf reabsorption most appropriate a- Arachnoid vili b- Choroid plexus 63.Q. A person has glucosuria but his blood sugar is 100 mg/dl.what was the cause ,... a. decreased absorbtion of glucose from proximal convulated tubules b.dec thershold for glucose in kidney c.pt is diabetic d. abnormally decreased reabsorption of glucos 64.Q. main supply of head of femur in adults a- obturator artery b- medial and lateral circumflex femoral c- d- e- 64.Q. In stress,level of all hormones increases except a,growth b,adh c,cortisol d,aldosteron e) Insuline 65.Q.Difference b/w septc and hypovolumic shock., . temperature heart rate respiratory rate pallor hypotension 66.Q. A female was found to hav decreased calcium levels and increased phosphate and serium parathyroid hormone increased and alk. Phosphate is normal. cause may be a,hypoparathyroidisam b, chronic renal failure c) Osteomalacia e, psudohypoparathyroidsm 67.Q. isolated damage to anterior cruicate ligament leads to displacement of tibia on femur in which direction? a anterior b anteriomedial c anterolateral d posterior. 68.Q. foot drop nd loss of snesation on dorsum of foot following fracture of neck of fibula a.tibial n b,commen peronial nerve c.post tibial n d,sciatic nerve 69.Q.patient with anemia and jaundice has raised alkaline phophatase in his blood ...diagnosis a cholestrol stones b pigment stones

c cholengiocarcinoma d acute hepatistis e. blood malignancy 70.Q.14 year old girl with menorhagia and pale looking has presented with purpura her labs show platelete 20k and bone marrow shows megakaryocytic hyperplasia Dx a. ITP b. TTP c ... d ... e ... 71.Q.therapeutic as

well as toxic effect of loop diuretics is a metabolic acidosis b hyperkelemia c decrease bld pressure d. Increase in Na+ e........... 72.Q.a patient with pyogenic lung abscess develops meningitis causative agent? a streptococcus b staphylococcus c klebsiella d haemophilus influ e. pneumococci 73.Q.What is most appropriate abt thyroid gland... a)parathyroid lies on superolateral surface b)epithelium change acc to function c)isthmus lies above cricoid cartilage d).. * .. 74.Q. which of the following structure is buried in lateral sulcus of brain ? a.sebiculum B.operculam C.pars triangulris d. Insula e. splenium 75.Q.external jugular vein ... a. it pireces investing layer of deep cervical fascia at border of sternocleidomastoid b. It doesn t receive any tributaries ... c. formed behind angle of mandible Form on surface of sternocleidomastoid behind angle of jaw d. form by union of post div of retromandibular vein n postauricular vein 76.Q.organism with florescent pigment and resistant to antibiotics and disinfectants a pseudomona b bacteroides c trepnema d...... e......... 77.Q.Median urachal ligament is a remanant of a)umblical artery b)umblical vein c)urachus d) mesonephric duct 78.Q. Subarachnoid space end at level of a)L1-L2 b)L3-L4 c)L5

d)S2-S3 79.Q.A disorderly growth with change in size shape maturation. Which is also reversible a)anaplasia b)metaplasia c)dysplasia d)neoplasia 80.Q. which of the following is responsible for the net reabsorption of sodium in the kidney? a. aldosterone b. atrial natriuretic peptide c. Renin angiotensin system d. aldosterone and ANP 81.Q.which is the short term iportant effect of angiotensin II? a. vasoconstriction b. stimulation of the thirst center 83.Q.asthmatic pt ph 7.33, co2 48, hco3 25 ? a repiratory acidosis with renal compensation b resp alk c met aci d met alk e respiratory acidosis without renal compensation 84.Q.a women is given multiple transfusions of blood before and after the surgery, what will the ECG changes, her ECG doesn t show any ischemic changes? a hyperkalemia b hypercalcemia c Infrective endocarditis d 85.Q.Regarding epithelia and glands a) An endocrine glands is marked by the presence of number of ducts b) The simple squamous epithelium found at places where exchange of gases take place c) Halocrine type of secretion in mammary gland d)Most of respiratory tract is lined by transitional epithelium 86.Q.pulmonary capillary wedge pressure a)indirectly measures left atrial pressure b)indirectly measures right atrial pressure c)is named because of wedge shape of catheter d) Increase pressure across tricuspid valve 87.Q.In autosomal dominant disease a).both parents of affected child have the disease b)only one parent of affected child has the disease c)only male are affected from diseased parent 88.Q. Bio-availability is a factor, which route of administration of drug highly affects? a-oral b-iv c-sc d-im

e-sub lingual 89.Q. edema is caused by : a)Decreased hydrostatic pressure b)Increased osmotic pressure c)lymph obstruction 90.Q.most of the lymph is filtered by : a)peyer's patches b)lymph nodes c)spleen d)thymus 91.Q.Volume of distribution of drug not affected by a)age b)gender c)Sex d)cardiac failure e)pregnancy 92.Q.Infusion of large amount of dextrose in water.wht wd b inhibited a)ADH b)aldosterone c)vasopressin d)cortisol e)insulin 93.Q.The transitional epithelium lining the urinary bladder is derived from (A) ectoderm (B) endoderm (C) mesoderm (D) endoderm and mesoderm (E) neural crest .. 94.Q.clostridium botulinum specific symptoms in food poisoning... a.diarrhoea b.flacid paralysis of respiratory muscles c.projectile vomitng d.Convulsions 95.Q.ant triangle of neck is supplied by... a. C1. b.C2 nd C3 c.C3 nd C4 d,C4 96.Q.cavernous sinus cavity contains which nerve... a. Optic Nerve b. Occulomotor nerve c. Troclear Nerve d. Abducent Nerve

e. Glossopharyngeal nerve 97.Q.41 percnt hematocrit means a) 41% of formed elements r rbcs. b) 41% of blood volume is rbcs,wbcs n platelets.. c) 41% of blood volume is serum. d).41% of blood volume is plasma e) 41% of blood is hb 98.Q.in severe dehydration... a.ecf decreases b.icf decrease c.both ecf nd icf decreases d.pH decreases 99.Q.A woman is injected a PPD s/c. 48 hrs later she developed 14mm ,which cell other thn macrophages is formed... a.neutrophils b.T cell c.B cell d.lymphocytes. 100.Q.thromboxane A2 is secretd by... a.platelets b.endothlial cells c.basophils d.basophils 101.Q.a pregnant lady of 15 weeks developed thyrotoxicosis which drug is treatment of choice a) beta blocker b) PTU c) MgSO4 102.Q..avidin has greatest affinity to one of following a) B12 b) Biotin c) vitamin A d) vitamin C 103.Q.regarding Actinomyces infection wat is true a. forms pus b. forms pus and granuloma c. form non caseating granuloma d. form caseating granuloma e necrosis 103.Q.a know hypertensive on drug therapy..present in emergency with collapse..her plasma K is 6.1..what is the likely cause of collapse A..ARF B..CRF c...infection D..diuretics E..coushing 104.Q.blood antigens

a)agglutins b)secreted in saliva 105.Q. A baby with history of delayed passage of meconium, and on rectal biopsy there is absence of ganglion cells. What is the diagnosis. a. Cystic Fibrosis b. Hirschsprung disease c. ? d. ? 106.Q. A patient had cut in the center of wrist during a suicide attempt, he has no abduction or adduction of fingers plus no abduction of the thumb, the injury is to: a. ulnar nerve b. median nerve c. radial nerve 107.iron store in paranchyma of organ a)ferritin b)hemosedrin c)transferrin 108.Q. A gynecologist is treating UTI in her patients, She divided her patients in 2 groups, and 2 antibiotics were selected amoxicillin and ciprofloxaicn. each group is given 1 drug without letting them know the real name of the drug. what type of this study is. a. Double Blind b. Retrospective c. Cross Sectional d. Placebo e. Case Control 109.Q. Adult polycystic kidney disease, which of the following is correct a. Autosomal Dominant b. Autosomal Recessive c. X Linked d. Multifactorial e. Mitochondrial 110.Q. Which of the following test is best described for GFR kidney a. Serum Urea b. Urine Osmolality c. Hippuric Acid Test d. Insulin Clearance e. Creatinine clearance 111.Q.Which of the following beta blocker should be given with no vasodilation but lowers BP a. Captopril b. Hydralazine c. Nifedipine d. Atenolol e. Verapamil 112.Q. Peritonitis is caused by a) Bacteroids b) E-Coli c) Proteus d) Steph 113.Q. An alcoholic patient has h/o loss of appitite, addominal distension ,on liver histopathology a) mailiory body appearance b)

114.Q. child with purpura on investigation he has a) paleteles 90000 b) platelets 20000 c) factor 8 deficincy d) protien c deficiency e) protien S deficiancy 115.Q.6 yr child with peripheral edema decrese albumin level , skin lesions what is the cause a. kawashkior b.marasmus c)beri beri d)vit c deficiency 116.Q. anitbodies against tb present a.is complete b..attached to bacteria c.Serum d. lymphoctes 117.Q. Blow on jaw cause RAmus fracture just above the mandibular foramin at mandibal ,lesion causes. a.mylohyoid b.skin of chin anesthesia c.lower teeth anesthesia d. 118.Q.Which activates thirst center a). ADH b) Aldosterone c) Renin d) Angiotensin e) ANP 119.Q. Which of the following helps in regulation of sodium absorption a). Atrial Natriuretic peptide b) ADH c) Aldosterone d) Aldosterone + Atrial Natriuretic peptide e) Renin 120.Q. Stimulus for aldosterone secretion a)hypekalemia b)renin c)hypernatremia 121.Q. Which of the following disease is caused by the bite of mosquito a) Ochronosis b) Filariasis c) Whipple d) Ascariasis 122.Q. Enzymes which transfer radical from one molecule to another a)hydrolases b)oxidoreductases* c)transferases d) Oxidation

November 2013

1. A Female during delivery loses blood and requires blood. Her blood sample is reactive blood agglutinates with anti-sera B and anti-sera D. which blood is suitable for transfusion.

A. A+

B. B RH Positive

C. O +

D. AB +

E. .

2. arches over left lung root.

A. Thoracic duct

B. Arch of aorta

C. Azygos vein

D. .

E. .

3. Patient IVC is blocked just above the emergence of azygos vein, where blood will divert.

A. Right gastric artery

B. Hepatic vein??

C. Hepatic artery

D. Umbilical artery

E. Splenic artery

F. abdominal veins

4. Internal Jugular vein is related

A. Anterior to Carotid artery

B. Medially to Carotid Artery

C. Laterally to Carotid artery

D. Posteriorly to Carotid artery

E. Internal Carotid Artery posteriorly

5. Rapid adaptation receptors

A. Free nerve endings

B. Meckels disk

C. Pacinian corpuscles

D. Ruffini's corpuscles

E. barorecceptors

6. Hyper-magnesaemia causes

A. Hyperreflexia

B. Dec acetylcholine uptake

C. Increase acetylcholine release

D. .https://www.facebook.com/FCPS.Q.BANK

E. .

7. Best example against single organ?

A. Hashimoto thyroiditis

B. PAN

C. SLE

D. RA

E. .

8. Hormone required for brain development

A. Thyroid hormone

B. Growth hormone

C. Cortisol

D. Androgen

E. Insulin

9. Ketamine used in repeated burn dressings because

A. It does not cause hypotension

B. Causes profound analgesia

C. It can be given IV

D. It does not causes addiction

E. It’s not narcotic

10. Hanging causes death by

A. Fracture of odontoid process

B. Fracture of atlas

C. .

D. .

E. .

11. Mechanism of action of propylthiouracil

A. Inhibition Iodine pump

B. Blocks the synthesis of thyroid hormone.

C. Blocks the synthesis of thyroglobulin.

D. Inhibits hormone release

E. Decreases TSH

12. Last thing to be returned normal after losing a litter of blood

A. Heart rate

B. Blood pressure

C. Cardiac contractility??

D. RBC in peripheral smear

E. Pulse pressure

F. Volume

13. Antibodies are produced by

A. Lymphocytes

B. Plasma cells

C. T-Cells

D. Neutrophils

E. Endothelium

14. 15 year old male had history of right iliac fossa pain for 18 hours and was operated for appendicitis, histopathology will show which cell

A. Lymphocytes

B. Macrophages

C. Neutrophils

D. .

E.

15. Which of congenital malformation is most common

A. ASD

B. VSD

C. TS

D. .https://www.facebook.com/FCPS.Q.BANK

E. .

16. Male with Trans-mural infarction died suddenly in washroom after 8 days.

A. Atrial fibrillation

B. Ventricular Fibrillation

C. Cardiac Tamponade

D. Thromboembolism

E. Pulmonary oedema

17. After trauma Female with sudden acute chest pain, Dyspnoea, haemoptysis and shock and then death.

A. Fat embolism

B. Air Embolism

C. Pneumonia

D. .

E. .

18. G1P2 female after delivery develops sudden chest pain and difficulty in breathing and haemoptysis, ECG shows S1 Q3 T3 pattern which is most appropriate test.

A. LDH

B. SGO?PT

C. X-Ray

D. CPK

E. gallium scan

19. In complete Glucose metabolism number of ATP

A. 30

B. 32

C. 36

D. 44

E. 48

20. Male breathing with Tidal volume 500ml and RR of 10/m what will be the volume.

A. 1000

B. 3500

C. 3000

D. 4800

E. 5000

21. After forced expiration residual volume will be

A. 500

B. 1000

C. 1200

D. 2400

E. ?? volume remaining in the lungs after forced expiration.

22. A female with regular cycle of 21 to 23 days what will be the ovulation days

A. 12 – 14

B. 14 – 18

C. 7 – 9

D. 10-12

E. .

23. A 46 year old farmer with history of discharging sinus on foot, smear shows red granule and filaments 1-3 microns, which is most appropriate

A. Actinomyces

B. Corynebacterium

C. Medurula mycetoma

D. Actinomyces pellettieri

E. .

24. 15 year Gardner with history of chest pain, no other symptoms, X-Ray was done which showed Round mass which is calcified

A. Aspergillosis

B. Tuberculosis

C. Sarcoidosis

D. Hydatid cyst

E. .

25. Young boy with 3 week history of facial weakness and nasopharyngeal sinusitis, on examination bilateral facial weakness, with drooling on mouth

A. H. Influenzae

B. Corynebacterium

C. .

D. .

E. .

26. Patient with defect in lumen of allantois

A. Meckel's diverticulum

B. Umbilical Sinus/fistula?

C. Urachal Fistula

D. Urachal Cyst

E. Urachal Sinus

27. A 59 female Non-Insulin dependent diabetes and HTN on antihypertensive brought to the emergency with semi collapsed state, K+ is 6.1 what is the cause?

A. ARF

B. CRF

C. Diuretics

D. Heart Failure?

E. .

28. Male brought to the ER with critical condition, ABGs showed PH 7.25 PCO2 65 and HCO3 24.

A. Acute Respiratory Acidosis

B. Respiratory alkalosis

C. Partially Compensated Respiratory Acidosis

D. Partially Compensated Respiratory Alkalosis

E. Respiratory and metabolic Acidosis

29. Which of tumours does not metastasize

A. Basal cell carcinoma

B. Squamous cell carcinoma

C. Breast Carcinoma

D. Bronchial Carcinoma

E. neuroblastoma

F. RCC?

30. Common peroneal nerve is related to

A. Biceps femoris medially

B. Biceps femoris laterally

C. .

D. .

E. .

31. Drug that is contraindicated in Intracranial HTN

A. Ketamine

B. Thiopental

C. Fentanyl

D. Midazolam

E. .

32. A healthy man with severe dehydration can be differentiated from SIADH

A. Plasma osmolarity

B. Urine Osmolarity

C. ADH Level

D. Free Water Clearance

E. Corticopapillary Osmotic Gradient

33. A patient had resection of terminal ileum, what will result

A. Decreased Amino acid absorption

B. Increased water content in stool

C. Increased enterohepatic circulation

D. decreased absorption of iron

E. .

34. A sharp object touches the foot patient withdraws.

A. Multisynaptic reflex

B. .

C. .

D. .

E. .

35. Ejaculatory duct opens at

A. Prostatic urethra

B. .

C. .

D. .

E. .

36. Regarding renal tubular absorption which of the following is passively absorbed.

A. Na

B. Cl

C. Urea

D. Ca

E. Glucose

F. NH3?

37. Regarding sarcoplasm of muscle fibre is between

A. Two Z-Lines

B. Transverse tubules

C. H-Band

D. A-Band

E. .

38. Young male comes to you with the history of problem in erection and is embarrassed by his enlarged breasts.

A. Prolactinoma

B. Mineralocorticoid tumour???

C. Increased CRH

D. Increased gonadotrophic hormones.

E. .

39. Type 2 heart Block

A. Distorted ECG Complexes

B. Atrial rate is greater than ventricles

C. ventricular rate is greater than atria

D. .

E. .

40. Nerve supply of dorsum of hand just near thumb

A. Median nerve

B. Radial nerve

C. Axillary nerve

D. .

E. .

41. Cystic artery is branch of

A. Gastroduodenal

B. Left gastroepiploic

C. Right hepatic

D. .

E. .

42. How much pressure is required for the opening of aortic valve?

A. 50

B. 100

C. 60

D. 80

E. .

43. True regarding Trigeminal ganglia

A. Completely covered by Dura

B. Anterior portion lies in trigeminal canal

C. Is lies beside cavernous sinus

D. Has branches from anterior and posterior parts

E. .

44. Fastest conduction in

A. A alpha

B. A beta

C. A delta

D. B Fibres

E. C Fibres

45. Isthmus of thyroid gland lies at

A. Thyroid cartilage

B. C2-C3-C4 tracheal ring

C. Above Cricoid

D. C4-C5

E. .

46. Phonation is produced by

A. Vocal cords

B. Folds of vocal cords

C. vibration of vocal cords

D. .

E. .

47. Pharyngeal part of Deglutition

A. Voluntary

B. .

C. .

D. .

E. .

48. Foramen cecum represents embryological structure.

A. Thyroid

B. Thymus

C. .

D. .

E. .

49. AFP is raised in

A. HCC

B. .

C. .

D. .

E. .

50. Patient presented with inappropriate Speech

A. Boca’s

B. Wernicke

C. .

D. .

E. .

51. Amoebic liver abscess test done to diagnose

A. X-Ray

B. CT

C. IHA

D. Amoeba in stool

E. .

52. Trauma to Pterion will cause bleeding of

A. Middle meningeal artery

B. .

C. .

D. .

E. .

53. Female with cholelithiasis which enzyme

A. AST

B. ALT

C. Alkaline Phosphatase

D. GGT

E. .

54. Increased GFR is caused by

A. Decreased arterial pressure

B. Increase thickness of glomerular membrane

C. Aldosterone?

D. Decreased Oncotic pressure.

E. decreased glomerular pressure

55. HIV+ patient surgery done then which antiseptic to use after surgery to clean floor

A. 1% hypochlorite

B. 4% hypochlorite

C. Glutaraldehyde

D. Soap and water

E. Water

56. superficial incision in Submandibular gland surgery will cause damage to

A. Lingual nerve

B. Hypoglossal nerve

C. .

D. .

E. .

??The marginal mandibular nerve

57. Patient having progressive facial weakness for 3 months and hemiplegia lesion is in. He is also with intention tremors

A. Pons

B. Cerebrum??

C. Supranuclear

D. Cerebello-Pontine Angle

E. .

58. Which amino acid is essential

A. Phenylalanine.

B. .

C. .

D. .

E. .

59. Renal flow is measured by.

A. Inulin

B. Para aminohippurate

C. Glucose

D. Na

E. .

60. Gustatory sweating is caused by.

A. superficial parotid gland surgery

B. .

C. .

D. .

E. .

61. Regarding facial nerve

A. .

B. .

C. .

D. .

E. .

62. Heparin action on DVT, it prevents

A. Embolization

B. Organization

C. Propagation

D. .

E. .

63. Which of the following is primary cartilaginous joint.

A. Costochondral

B. Symphysis pubis

C. Sutures of skull

D. .

E. .

64. Boy with lymphadenopathy painless, biopsy large cells with multiple mitoses, appropriate diagnosis by

A. Lymphocytosis on peripheral smear

B. Immunohistochemistry of leukocytes

C. .

D. .

E. .

65. Female with fever, malaise enlarged cervical lymph nodes biopsy reveals granulomatous lesions, appropriate diagnosis

A. Chest X-Ray

B. AFB demonstration

C. .

D. .

E. .

66. Person from sibbi Balochistan with history of fever, anorexia and fly bite, and examination showed hepatosplenomegaly, lymphadenopathy.

A. Kala-azar

B. Malaria

C. Loiasis

D. .

E. .

67. Lymphoma with cervical enlargement and splenic involvement stage.

A. Stage I

B. Stage IIa

C. Stage IIb

D. Stage III

E. Stage IV

68. Regarding spleen

A. Related to Rib 5 and 6

B. Related to left colic flexure in lower pole

C. Developed from ventral mesentery

D. .

E. .

69. flexor sheath of thumb contains

A. flexor pollicis longus

B. Flexor pollicis longus and abductor pollicis longus?

C. Flexor pollicis brevis

D. Flexor pollicis longus

E. Flexor pollicis longus, synovial membrane and valla something….???

70. truncal vagotomy causes

A. decreased motility

B. decreased acid secretion

C. decreased pepsin secretion

D. .

E. .

71. Histopathology grade of poorly differentiated tumour

A. 25% undifferentiated

B. 25 - 50 % undifferentiated

C. 50 – 75 % undifferentiated

D. More than 75 % undifferentiated

E. .

72. Idiopathic thrombocytopenic purpura which of the following is prolonged

A. aPTT

B. PT

C. BT

D. CT

E. Thrombin time

73. Factor IX is not available what next best choice is.

A. Cryoprecipitate

B. FFP

C. Platelets

D. Whole Blood

E. .

74. Factor VIII is not available what next best choice is.

A. Cryoprecipitate

B. Platelets

C. Whole Blood

D. PCV

E. FFP

75. Epiploic Appendages are on

A. Duodenum

B. Ileum

C. Jejunum

D. Sigmoid colon

E. Stomach

76. Female after delivery has developed sepsis and DIC which test is NOT appropriate

A. Fibrin degrading products

B. Bleeding time

C. clotting time

D. .

E. .

77. Which of the following is predisposing oral condition of mouth for malignancy

A. Leukoplakia

B. Erythroplakia

C. lichen planus

D. .

E. .

78. Oestrogen containing pills are associated with

A. Breast cancer.

B. Thromboembolism

C. .

D. .

E. .

79. Female with right ovarian fibrosis, surgery is done which artery is most likely to be damaged.

A. External iliac

B. Internal iliac

C. Uterine artery

D. .

E. .

80. Testicular tumour will first drain to

A. External iliac nodes

B. Internal iliac nodes

C. Para aortic nodes

D. .

E. .

81. Regarding pempaniform plexus

A. In inguinal canal

B. Liver

C. Spleen

D. Kidney

E.

82. Hernia medial to inferior epigastric artery.

A. Indirect

B. Direct

C. Femoral

D. .

E. .

83. Regarding kidney

A. Kidney and surrounding fat covered by gerota fascia

B. Gleason’s capsule

C. Peritoneum

D. .

E. .

84. Spinal cord anteriorly attached to

A. Alar ligament

B. Filum terminale

C. .

D. .

E. .

85. Regarding spironolactone

A. IV dose 100 mg

B. Is steroid

C. .

D. .

E. .

86. Which of the following disease in pregnancy will cause congenital cataract

A. Measles

B. Rubella during pregnancy

C. .

D. .

E. .

87. If there is a tumour in the right superior lobar bronchus the Bronchopulmonary segment most likely to be collapsed would be:

A. Apical superior

B. Anterior Basal

C. Medial Basal

D. Middle lateral

E. Superior Basal

88. Bronchogenic carcinoma

A. Smoking

B. Asbestosis

C. .

D. .

E. .

89. 1 year boy with anaemia showing microcytic cells, failure thrive, elder brother regular blood transfusion

A. Haemophilia

B. Sickle cell anaemia

C. Thalassemia

D. .

E. .

90. Two brothers having haemophilia and but sister does not have what is inheritance

A. Autosomal Dominant

B. Autosomal Recessive

C. X-Linked Dominant

D. X-Linked Recessive

E. .

91. Left circumflex artery supplies

A. .

B. .

C. .

D. .

E. .

92. Diabetic Ketoacidosis patient managed but dies, infection

A. Mucur

B. Pseudomonas

C. TB

D. .

E. .

93. Patient developed SCC of bladder 8 years back had granulomatous appearance of bladder biopsy.

A. Schistosoma

B. Tuberculosis

C. Bladder stone

D. Nitrosamines

E. .

94. Vein of heart which itself converts to coronary sinus.

A. Great cardiac vein

B. Middle cardiac vein

C. .

D. .

E. .

95. Female with high grade fever, anaemia and haematuria

A. P. falciparum

B. .

C. .

D. .

E. .

96. Corpus Striatum

A. Amygdaloidal nucleus + Globus Pallidus

B. Caudate nucleus + Globus pallidus

C. Amygdaloidal Nucleus + Lentiform Nucleus

D. Amygdaloidal Nucleus + Putamen

E. Caudate Nucleus + Putamen

97. Most common intracellular buffer

A. HCO3

B. Haemoglobin

C. PO4

D. Na

E. Protein

98. Oxygen binding protein in muscle

A. Myoglobin

B. haemoglobin

C. troponin

D. tropomyosin

E. actin

99. An Osmotic Diuresis results from

A. Mannitol

B. Aldosterone

C. Furosemide

D. Hyperinsulinism

E. Ingestion of Alcohol

100. Pharmacodynamics Drug-Drug interaction

A. Thiazide and lithium

B. Morphine and naloxone

C. Procaine and Adrenaline

D. Phenobarbital and warfarin??

E. .

101. Pus that accumulates in boils or abscess is mainly composed of

A. Dead bacteria

B. Dead Neutrophils

C. Exudate

D. Monocytes

E. .

102. Basic drug binds to

A. Albumin

B. Iron

C. Blood Cells

D. A1 Glycoprotein

E. Protein

103. Chromosome lines in centre in

A. Metaphase

B. Prophase

C. Anaphase

D. Telophase

E. Prometaphase

104. Signs of Apoptosis

A. Karyolysis

B. .

C. .

D. .

E. .shrinkage

105. Male presents with Stoney dull percussion on right sided of chest what is the cause

A. Pleural effusion.

B. Pneumonia

C. Thickened parietal Pleura

D. Pneumothorax

E. .

106. Male died after adenocarcinoma, autopsy showed thousands of polyps in colon, type of polys.

A. Adenomatous

B. Hyperplastic

C. Hamartomatous

D. Metaplastic

E.

107. Which of the following is blood supply of head of femur

A. Medial circumflex humeral

B. Lateral circumflex humeral

C. Obturator

D. Nutrient

E. .

108. Flexor of knee (except)

A. Sartorius

B. Gastrocnemius

C. Adductor Magnus

D. Biceps femoris

E. .

109. Major Breast lymph nodes, to parallel???

A. Along Axillary vessels apical nodes.

B. Along intercostal vessels to posterior thoracic node,

C. Along internal thoracic to internal thoracic nodes???

D. .

E. .

110. Biopsy of tissue shows Lymphoid tissue with stratified squamous epithelium

A. Palatine tonsils

B. Lymph nodes

C. Peyer's patches

D. Thymus

E. .

111. Basophilia is caused by

A. Nucleus

B. Ribosomes

C. Cytoplasm

D. Endoplasmic reticulum

E. .

112. Regarding spinal nerves

A. Exit from intervertebral foramen

B. Derived from neural crest only

C. Ventral horn contains ganglion

D. Motor supply from dorsal root

E. .

113. A 25 years old Female having complains of dysphagia, and weakness labs show hb=6.2 mg/dl MCV=68 fl and target cells in peripheral film, what is the diagnosis

A. Iron deficiency anaemia

B. Anaemia of chronic disease

C. Thalassemia

D. .

E. .

114. Cervical cancer increased risk in

A. Chronic irritation

B. IUCD

C. HPV

D. .

E. .

115. Female with Cushing disease came for investigations, her cortisol level is <1 what is most important question to ask

A. Having Headache

B. Taking any steroid

C. .

D. .

E. .

116. Patient with CRF on dialysis with anaemia what should be given

A. Erythropoietin

B. .

C. .

D. .

E. .

117. Regarding trachea

A. Gaps in the C-shaped Cartilage rings lie anteriorly

B. Total length of trachea is 15 cm

C. It commences at lower border of cricoid

D. It is attached to the upper margin of cricoid cartilage

E. Recurrent laryngeal nerve lie anteriorly

118. Painful defecation nerve supply

A. Pudendal nerve

B. .

C. .

D. .

E. .

119. Boy with high grade fever and tender abdomen, X-Ray shows pneumoperitoneum, before surgery antibiotic should be given

A. Cefotaxime?

B. Gentamycin

C. Augmentin

D. .

E. .

120. Patient with C. Botulinum food poisoning, characteristic feature will be

A. Diarrhoea

B. Vomiting

C. Flaccid paralysis of respiratory muscles

D. Convulsions

E. .

121. Following muscle does not attach to humerus

A. Pectoralis major

B. Pectoralis minor

C. Teres minor

D. Subscapularis

E. Supraspinatus

122. Patient with Tobacco chewing showing ulcer on inner lip margin which is indurated and pale is

A. Squamous cell carcinoma

B. Basal cell carcinoma

C. Melanoma

D. .

E. .

123. Medial longitudinal arch pillar

A. Talus

B. Calcaneus

C. Navicular

D. .

E. .

124. Structures posterior to medial malleolus except.

A. Tibial nerve

B. Post tibial artery

C. Flexor hallucis longus

D. Flexor hallucis brevis

E. Tibialis anterior

125. Ribosomes

A. Site of protein synthesis

B. Attached with ER and synthesize cytoplasmic protein

C. Present in cytoplasm and synthesize protein

D. Synthesize messenger RNA

E. .

126. Sarcomere lies between

A. Z disc

B. H lines

C. M lines

D. .

E. .

127. Disease not transmitted by Blood Transfusion?

A. Hepatitis A

B. CMV

C. EBV

D. .

E. .

128. Disease transmitted by blood?

A. Hepatitis B

B. Salmonella

C. Mycobacterium Tuberculosis

D. Vibrio Cholera

E. .

129. Philadelphia chromosomes

A. CML

B. ALL

C. Hodgkin's lymphoma

D. AML

E. .

130. A young boy deteriorated drastically 2 hours after tonsillectomy. He has tachycardia and hypotension. Most likely pathogenesis is?

A. Anaphylaxis shock

B. Cardiogenic Shock

C. Hypovolemic Shock

D. Septic Shock

E. Traumatic Shock

131. Regarding thyroid Gland

A. Comprises of acini drained by collecting ducts

B. Epithelium changes its shape depending on the stage of activity

C. Has parathyroid glands lying on anterolateral surface

D. .

E. .

132. Regarding arterial supply of heart all statements are true except that

A. left Coronary Artery is larger than Right Coronary Artery

B. Right Coronary artery arises from anterior aortic sinus

C. Left Coronary Artery is the first branch of arch of aorta

D. Right Coronary Artery supplies both ventricles

E. Interventricular septum is supplied by left coronary artery

133. Most fatal type of pulmonary embolism that causes extensive pulmonary necrosis, shock and then death

A. Fat Embolism

B. Thromboembolism

C. Air Embolism

D. Amniotic Embolism

E. .

134. Free Nerve endings

A. are non-encapsulated receptors

B. Are found in voluntary muscles

C. Are a type of special visceral enteroreceptor

D. Are not present in the epidermis of skin

E. Detect only pain

135. Renal cell Carcinoma Metastasis by

A. Renal Arteries

B. Renal Veins

C. Lymphatic

D. .

E. .

136. Autonomic Fibres are

A. A Alpha fibres

B. A Beta Fibres

C. A gamma Fibres

D. B Fibres

E. C Fibres

137. Regarding Information care session what is appropriate?

A. Myths regarding disease of patient are cleared

B. Updated information regarding the disease and its treatment advancements are communicated

C. Friends of patient are questioned about patients conditions

D. .

E. .

138. When is confidentiality of patient breached

A. Patient dies

B. Insurance Purposes

C. Psychiatric Illness

D. .

E. .

139. Most commonly hypertrophy occurs in

A. Skeletal muscles

B. Thyroid Gland.

C. Ovaries

D. Breast

E. Testis

140. After road traffic accident patient is suffering from memory loss, which part of brain is involved

A. Hippocampus

B. Parietal Lobe

C. Temporal Lobe

D. .

E. .

141. A female had bilateral silicon breast implant placements, now she has arrived with inflammation, which cells will be demonstrated?

A. Lymphocytes

B. Giant Cells

C. Plasma cells

D. Neutrophils

E. Eosinophil

142. Vomiting centre is located in

A. Medulla Oblongata

B. Cerebral Cortex

C. Cervical Spinal cord

D. Internal capsule

E. Hypothalamus

143. which of the following is NOT associated with hormonal secretion

A. Chondrosarcoma

B. Teratoma

C. Bronchiogenic Carcinoma

D. ArrhinoBlastoma

E. Small Cell Carcinoma Lungs

144. Which of the following is most important cause of Fat necrosis in peritoneal cavity

A. Acute pancreatitis

B. Gut gangrene

C. Brain

D. .

E. .

145. Which one the following is only capable of utilizing glucose

A. Brain

B. Heart

C. Liver

D. Skeletal Muscles

E. .

146. Down syndrome is associated with at the age of 40

A. Alzheimer’s disease

B. Parkinson’s

C. .

D. .

E. .

147. Regarding Placenta

A. Separates at the level of spongiosum level of uterus

B. Covered with amnion on foetal side

C. Is also called feto-chorionic

D. .

E. .

148. Eosinophilia is not associated with

A. IgM

B. Ascariasis

C. Asthma

D. Hay Fever

E. IgE

149. 15 year old boy presented with purpura

A. Platelets 20 x 10^9

B. Platelets 90 x 10^9

C. Deficiency of calcium

D. Deficiency of factor viii

E. .

150. Which one produces severe transfusion reaction

A. A- to A+

B. O to AB

C. A to AB

D. .

E. .

151. Staging of tumour is related with

A. Invasive extent

B. Cellular atypia

C. Hyperchromasia

D. Mitotic Bodies

E. .

152. Venous return is decreased by

A. Skeletal muscle paralysis

B. Venoconstriction

C. Increased Blood Pressure

D. Increase Cardiac Output

E. .

153. During Increase in Heart Rate which of the following occurs

A. Diastolic Period decreases more as compared to Systolic Pressure

B. Systolic pressure decreases more as compared to Diastolic pressure

C. Diastolic and systolic pressure remains constant

D. Systolic pressure decreases as diastolic

E. No Change.

154. Most appropriate function of Sternocleidomastoid muscle

A. turns the neck to opposite side against resistance

B. Turns the neck to the same side against resistance

C. Flexes the neck

D. Extends the neck

E. .

155. CO2 diffusion in lungs is greater than O2 because

A. Greater solubility coefficient

B. Increased CO2 Partial pressure in lungs

C. .

D. .

E. .

156. An acute decrease in arterial pressure elicits which of the following compensatory changes?

A. Decrease Firing rate of carotid sinus.

B. Increase parasympathetic outflow to the heart.

C. Decrease heart rate.

D. Decrease contractility

E. Decreased mean systemic pressure.

157. Which is the neurotransmitter involved in slow wave sleep.

A. Acetylcholine

B. Dopamine

C. Adrenaline

D. Serotinin

E. GABA

158. Diastolic blood pressure is distributed normally in a group lady teachers (N=75). Mean was 80 mmHg and standard deviation of 10, approximately what percentage of teachers have diastolic blood pressure of 70 mmHg or greater?

A. 16 %

B. 34%

C. 48%

D. 84%

E. 96%