extranodal lymphoma: waldeyer’s ring lymphomas, primary muscle lymphoma sinus lymphomas, bone...

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Extranodal Lymphoma : Waldeyer’s Ring Lymphomas, primary Muscle Lymphoma Sinus Lymphomas , Bone Lymphoma Salivery Gland Lymphoma, Pancreatic Lymphoma Thyroid Lymphomas , Cardiac Lymphomas Nasal and nasopharyngeal Lymphomas Adnexal lymphomas, Uterine & Cervical Lymph . Ocular Lymphomas , Pulmonary Lymphomas Central Nervous Lymphomas Prostatic Lymphoma Gastric Lymphoma , Small Bowel Lymphomas Large Bowel and Anorectal Lymphomas ] Dr.Azarm

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Extranodal Lymphoma:

Waldeyer’s Ring Lymphomas, primary Muscle Lymphoma

Sinus Lymphomas , Bone Lymphoma

Salivery Gland Lymphoma, Pancreatic Lymphoma

Thyroid Lymphomas , Cardiac Lymphomas

Nasal and nasopharyngeal Lymphomas

Adnexal lymphomas, Uterine & Cervical Lymph .

Ocular Lymphomas , Pulmonary Lymphomas

Central Nervous Lymphomas Prostatic Lymphoma

Gastric Lymphoma , Small Bowel Lymphomas

Large Bowel and Anorectal Lymphomas]

Hepatic Lymphomas, Breast Lymphomas

Splenic Lymphoma Bladder Lymphoma

Renal Lymphomas , Testicular Lymphoma

Dr.Azarm

Extranodal means 'beyond nodal' Sites are identified by the following notation :

 Lymph nodes 

 Liver (hepatic)

 Lung

 Bone marrow 

 Spleen 

 Pleura (lung) 

 Bone 

 Skin (dermis)

Dr.Azarm

Nonspecific Symptoms of lymphoma may Include the following:

Fevers(nonspecific) Chills

Unexplained weight lossNight sweatsLack of energyItching

Dr.Azarm

Dr.Azarm

Ovarian Lymphoma:

Primary ovarian lymphoma associated with Meigs' syndrome.

Primary ovarian lymphoma manifesting with severe hypercalcemia

HIV-associated primary non-Hodgkin's lymphoma of ovary.

Primary Ovarian Non H L with Autoimmune Hemolytic anemia.

PRIMARY GASTROINTESTINAL lymphomas constitute 5% to 10% of all

gastrointestinal tumors .Twenty percent to 30% of gastrointestinal lymphomas, or approximately 5% of peripheral non-Hodgkin’s lymphomas (NHL), in general, are primarily located in the intestine and differ from gastric lymphomas in clinical features, pathology, treatment,

and prognosis .

Primary malignant lymphoma of the thyroid

Accounts for <5% of all thyroid malignancies and is primarily treated with chemotherapy and external beam radiation.

With the advent of modern immunophenotypic analyses, fine-needle aspiration (FNA) can potentially obviate the need for surgical procedures

Testicular lymphoma is a rare extranodal presentation of non-Hodgkin lymphoma.

Testicular lymphoma

The risk of extranodal recurrence is high, especially in the central nervous system

Testicular lymphoma is almost always of an aggressive histologic subtype, usually diffuse large B cell type. In contrast to other patients with localized large cell lymphoma

the recommended treatment for all stages of testicular lymphoma is a full course of

chemotherapy as for advanced diseasechemotherapy:  CHOP+ rituximab

Testicular lymphoma

Liver LymphomaLiver Lymphoma::

Nine out of 10 patients with primary lymphoma of the liver presented in a manner that did not suggest a tumour.

The initial diagnoses were chronic active hepatitis in three cases and "granulomatous cholangitis", inflammatory pseudotumour, and anaplastic carcinoma in one case each

Peripheral T-Cell Lymphoma Arising in the Liver

pulmonary Lymphoma.

Mediastinal Lymphoma

pulmonary Lymphoma.

Mediastinal Lymphoma

Primary cardiac lymphoma

Patients may present with dyspnea, congestive heart failure, chest pain, epigastric pain, pericardial tamponade, conduction abnormalities, or arrhythmia. Acute myocardial infarction may be simulated by diffuse myocardial

infiltration .

Primary lymphoma of bone

Primary lymphoma of bone

CNS lymphoma may affect people whose immune system is not working properly.

for example, after organ transplants, or in people with HIV

:.primary CNS lymphomaThe most common site for a CNS lymphoma is the cerebrum

                                            

  The areas of the brain

Cutaneous T-cell Lymphoma:

Malignant Lymphoma bone marrow invasion.

Malignant Lymphoma skin invasion (Mycosis F).

Sezary syndrome.

MALT lymphoma:an indolent (commonly called low grade) type of

B-cell non-Hodgkin lymphoma

MALT lymphoma most frequently arises within this type of lymphoid tissue after it has accumulated as part of a

reaction to an infection or inflammation.

MALT lymphoma is the third most common type of non-Hodgkin lymphoma In GI.It is associated with Helicobacter pylori infection.

Sinus Lymphomas

Renal lymphoma has an insidious clinical presentation that occurs late in the course of the diseaseIt can present in many ways, however the most common are primary tumors presenting single or multiple nodules, or that involve the kidney, either in a hematogenic dissemination form or through a contiguous retroperineal disease

Renal lymphoma

Primary renal Iymphoma

The symptoms and signs of CNS lymphoma are often related to increased intracranial pressure ( ICP ), e.g. headache, mental change, or focal neurological deficits Notably, only 5% of CNS lymphoma patients experienced inner ear symptoms such as vertigo, tinnitus or progressive hearing loss [9]. Thus, clinically, vertigo accompanied by progressive hearing loss rarely occurs in CNS lymphoma.

CNS lymphoma

Splenic Lymphoma

Primary Nasal Lymphoma

Multiple maxillofacial extranodal sites of soft tissue mass with the presence of non-necrosis and uneven margin should be considered as the characteristic sign of NHL disease in the head and neck

Salivery gland lymphoma:

Salivery gland lymphoma