extranodal lymphoma: waldeyer’s ring lymphomas, primary muscle lymphoma sinus lymphomas, bone...
TRANSCRIPT
Extranodal Lymphoma:
Waldeyer’s Ring Lymphomas, primary Muscle Lymphoma
Sinus Lymphomas , Bone Lymphoma
Salivery Gland Lymphoma, Pancreatic Lymphoma
Thyroid Lymphomas , Cardiac Lymphomas
Nasal and nasopharyngeal Lymphomas
Adnexal lymphomas, Uterine & Cervical Lymph .
Ocular Lymphomas , Pulmonary Lymphomas
Central Nervous Lymphomas Prostatic Lymphoma
Gastric Lymphoma , Small Bowel Lymphomas
Large Bowel and Anorectal Lymphomas]
Hepatic Lymphomas, Breast Lymphomas
Splenic Lymphoma Bladder Lymphoma
Renal Lymphomas , Testicular Lymphoma
Dr.Azarm
Extranodal means 'beyond nodal' Sites are identified by the following notation :
Lymph nodes
Liver (hepatic)
Lung
Bone marrow
Spleen
Pleura (lung)
Bone
Skin (dermis)
Dr.Azarm
Nonspecific Symptoms of lymphoma may Include the following:
Fevers(nonspecific) Chills
Unexplained weight lossNight sweatsLack of energyItching
Dr.Azarm
Ovarian Lymphoma:
Primary ovarian lymphoma associated with Meigs' syndrome.
Primary ovarian lymphoma manifesting with severe hypercalcemia
HIV-associated primary non-Hodgkin's lymphoma of ovary.
Primary Ovarian Non H L with Autoimmune Hemolytic anemia.
PRIMARY GASTROINTESTINAL lymphomas constitute 5% to 10% of all
gastrointestinal tumors .Twenty percent to 30% of gastrointestinal lymphomas, or approximately 5% of peripheral non-Hodgkin’s lymphomas (NHL), in general, are primarily located in the intestine and differ from gastric lymphomas in clinical features, pathology, treatment,
and prognosis .
Primary malignant lymphoma of the thyroid
Accounts for <5% of all thyroid malignancies and is primarily treated with chemotherapy and external beam radiation.
With the advent of modern immunophenotypic analyses, fine-needle aspiration (FNA) can potentially obviate the need for surgical procedures
Testicular lymphoma is a rare extranodal presentation of non-Hodgkin lymphoma.
Testicular lymphoma
The risk of extranodal recurrence is high, especially in the central nervous system
Testicular lymphoma is almost always of an aggressive histologic subtype, usually diffuse large B cell type. In contrast to other patients with localized large cell lymphoma
the recommended treatment for all stages of testicular lymphoma is a full course of
chemotherapy as for advanced diseasechemotherapy: CHOP+ rituximab
Testicular lymphoma
Liver LymphomaLiver Lymphoma::
Nine out of 10 patients with primary lymphoma of the liver presented in a manner that did not suggest a tumour.
The initial diagnoses were chronic active hepatitis in three cases and "granulomatous cholangitis", inflammatory pseudotumour, and anaplastic carcinoma in one case each
Primary cardiac lymphoma
Patients may present with dyspnea, congestive heart failure, chest pain, epigastric pain, pericardial tamponade, conduction abnormalities, or arrhythmia. Acute myocardial infarction may be simulated by diffuse myocardial
infiltration .
CNS lymphoma may affect people whose immune system is not working properly.
for example, after organ transplants, or in people with HIV
:.primary CNS lymphomaThe most common site for a CNS lymphoma is the cerebrum
The areas of the brain
Cutaneous T-cell Lymphoma:
Malignant Lymphoma bone marrow invasion.
Malignant Lymphoma skin invasion (Mycosis F).
Sezary syndrome.
MALT lymphoma:an indolent (commonly called low grade) type of
B-cell non-Hodgkin lymphoma
MALT lymphoma most frequently arises within this type of lymphoid tissue after it has accumulated as part of a
reaction to an infection or inflammation.
MALT lymphoma is the third most common type of non-Hodgkin lymphoma In GI.It is associated with Helicobacter pylori infection.
Renal lymphoma has an insidious clinical presentation that occurs late in the course of the diseaseIt can present in many ways, however the most common are primary tumors presenting single or multiple nodules, or that involve the kidney, either in a hematogenic dissemination form or through a contiguous retroperineal disease
Renal lymphoma
The symptoms and signs of CNS lymphoma are often related to increased intracranial pressure ( ICP ), e.g. headache, mental change, or focal neurological deficits Notably, only 5% of CNS lymphoma patients experienced inner ear symptoms such as vertigo, tinnitus or progressive hearing loss [9]. Thus, clinically, vertigo accompanied by progressive hearing loss rarely occurs in CNS lymphoma.
CNS lymphoma
Multiple maxillofacial extranodal sites of soft tissue mass with the presence of non-necrosis and uneven margin should be considered as the characteristic sign of NHL disease in the head and neck
Salivery gland lymphoma: