epithelial pathology

Epithelial pathology

www.rxdentistry.blogspot.com

CASE 1


HISTOPATHOLOGY

B-Bulbous rete ridges 10 X-H&E

B-Moderate dysplasia 10X-H&E

A-Break in the continuity of basement membrane-10X-H&E

A-Hyperorthokeratinised epithelium10X-H&E


DIAGNOSIS

SQUAMOUS CELL CARCINOMA IN ASSOCIATION WITH VERRUCOUS LEUKOPLAKIA


CASE 2


HISTOPATHOLOGY

B-Para keratin plugging- 10x-H&E

A-Sub epithelial inflammatory infiltrate and features of mild dysplasia-40x-H&E

A-Hyperplastic epithelium- 4x-H&Ewww.rxdentistry.blogspot.com

DIAGNOSIS

VERRUCOUS CARCINOMA IN ASSOCIATION WITH ORAL SUBMUCOUS FIBROSIS


CASE 3


Sheets of malignant epithelial cells arranged within thin connective tissue septa-4x-H&E

Cellular and Nuclear pleomorphism 40 X-H&E

HISTOPATHOLOGY


Vascular invasion - 40 X-H&E

HISTOPATHOLOGY


Nuclear pleomorphism with mitotic figure- 40X-H&E

Area of necrosis 40X-H&E

HISTOPATHOLOGY


DIAGNOSIS

SINONASAL UNDIFFERENTIATED CARCINOMA


CASE 4


HISTOPATHOLOGY

Epithelial plugging 10x-H&E

Broad pushing margins into the connective tissue-10x-H&E

Surface epithelium showing plugging-10x-H&E

Parakeratinised stratified squamous epithelium with dysplasia-10x-


DIAGNOSIS

VERRUCOUS CARCINOMA. (CARCINOMA CUNICULATUM)


CASE 5


Sheets of spindle cells adjacent to an area of malignant epithelial cells. 10X-H&E

HISTOPATHOLOGY


Section shows pleomorphic epithelial cells along with spindle cells-40X-H&E

HISTOPATHOLOGY


Immunohistochemical stain, cytokeratin, epithelial cells, spindle areas


DIAGNOSIS

SPINDLE CELL SQUAMOUS CARCINOMA


CASE 6


Malignant epithelial island in connective tissue-10x-H&E

Dysplastic islands showing hyperchromatism-10X-H&E

HISTOPATHOLOGY


HISTOPATHOLOGY

Section shows numerous malignant cells with features of pleomorphism and mitotic figures-40x-H&E


DIAGNOSIS

MODERATELY DIFFERENTIATED SQUAMOUS CELL CARCINOMA


CASE 7


Island of dysplastic cells within the connective tissue-10x-H&E

Sheets of malignant epithelial cells-


HISTOPATHOLOGY

Section shows sheets of pleomorphic malignant cells-40x-H&E


DIAGNOSISPOORLY DIFFERENTIATED SQUAMOUS CELL

CARCINOMA


CASE 8


Acantholysis within malignant islands 10x-H&E

Lobular growth pattern 10x-H&E

Malignant epithelial islands and keratin pearls 10x-H&E

Dysplastic epithelium and break in continuity of basement membrane10x-H&E

HISTOPATHOLOGY


DIAGNOSIS

ADENOID SQUAMOUS CELL CARCINOMA –Variant of Squamous cell carcinoma.


CASE 9


HISTOPATHOLOGY

Photomicrograph shows atypical melanocytes in the basilar layer of overlying epithelium and spindle as well as round cells in the connective tissue (H&E), 10x.

Photomicrograph shows the junctional proliferation at the epithelial–connective tissue interface along with few epitheloid cells in the connective tissue (H&E), 40x.


Focal positivity for S100


DIAGNOSIS

DESMOPLASTIC MALIGNANT MELANOMA

Published as “Desmoplastic malignant melanoma of alveolus – A rare entity", in Oral Oncology EXTRA (2006) 42, 291– 294


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epithelial pathology

Documents

malignant epithelial

x surface epithelium

histopathology section

malignant epithelial

pleomorphic epithelial

histopathology photomicrograph

numerous malignant cells

histopathology parakeratinised