Department of Toxic Substances Control Cal/EPA

Bruce La Belle, Ph.D.Laboratory Chief

December 9, 2016Berkeley, CA

Environmental Chemistry Laboratory

Speakers Overview

Dr. Bruce La Belle

Analytical Chemistry Support Dr. Robert Ramage

Scientific Leadership, Biomonitoring, and Emerging Chemical Issues Dr. Myrto Petreas

External Perspectives

Mission

The Environmental Chemistry Laboratory provides scientific leadership

for DTSC in analytical and environmental chemistry to protect

public health and the environment from adverse effects of chemicals

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Vision

Nationally recognized scientific leadership in the analytical and

environmental chemistry of toxic chemicals for a healthy, sustainable, and

prosperous California

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Executive Decision-Making

Safer Products & Workplaces

Brownfields & Environmental Restoration

Analytical Testing

ConsumerProducts Testing

Environmental Chemistry &

Biomonitoring

ECL

Emerging Scientific Issues

Conceptual ModelDecember 9, 2016

HWMPEnforcement

OCIPermitting

Policy

Foundation for DTSC Decision-Making

& Scientific Expert Support

PresenterPresentation NotesI suggest to rework on animation. By looking at it, it doesnt capture my eyes at first time.

We Test a Wide Variety of Materials

Scientific Expert Technical Support

Analytical methods selection Project plans/sampling plan review Split sample testing Data quality review/interpretation/validation Training Reference Lab

Values Scientific Excellence Integrity Impartiality Independence Defensibility Consistency Traceability

Transparency Customer Service

Workplace Diversity Courtesy Respect

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ECL as an Organization

Analytical ChemistryDr. John Quinn

Quality Manager & Technical

Support

BiomonitoringDr. June-Soo Park

Environmental Chemistry

Dr. Myrto Petreas

ECL Lab Chief

Director

Chief Deputy Director

CleanupHWMPSafer Products & Workplaces

Environmental Justice

ECL as Centers of Excellence:The People

ECL-Berkeley : 37 Staff ECL Pasadena : 12 Staff

Visiting Scholars: ~10 Postdoctoral researchers, visiting professors

Graduate students, undergraduates Highly Experienced Scientists

PresenterPresentation NotesWe do not have visiting professor

MS17% is not really lined up

Centers of Excellence:Laboratory Infrastructure

ECL-Berkeley Specialized facilities including Clean Room laboratories

ECL-Pasadena New, state-of-the-art laboratory replaces 1950s facility

Ability to serve major areas of State Inter-laboratory method validations Continuity of operations in event of earthquake

Centers of ExcellenceState-of-the-Art Analytical Equipment

A

aa

GC-MS/MS GC-HRMS LC/MS/MS LC-QTOF-MS LC-ICP-MS ICP-OES GC-MS GC-ECD HPLC XRF

~$12 Million in instruments and other equipment

PresenterPresentation NotesI changed a bit to be consistent: e.g., GC/MS/MS GC-MS/MS

Quality Control Instrument calibration and monitoring Quality Control samples with every batch

Quality Assurance Standard Operating Procedures Review of data package by second chemist

Quality Management Manager review of each analytical report Performance Evaluation Samples

Demonstration of competency

Ensuring the Quality of Our Work

ECL has over 100 SOPs and Worksheets: Sample Receiving & Log-in Sample Preparation Sample Analysis Report Formats Glassware cleaning

EPA Standard Methods (SW-846) 8260B-Volatile Organics by GC/MS 8270C-Semivolatie organics by GC/MS 6010B-Total metals by ICP

Standard Operating Procedures

Foundation for Decision-Making

Current Core Program activities

Emerging issues that will affect DTSC in 1-5 years New chemicals New technologies New matrices New laws and regulations

PresenterPresentation NotesNew regulations?

Thank You

Department of Toxic Substances Control Cal/EPA

Analytical Support Berkeley

Robert Ramage, Ph. D.Supervisor

December 9, 2016Environmental Chemistry Laboratory

Introduction / Outline

What we do How we do it Types of special projects Uses of lab results

What We Do: Test Using EPA Methods

Organics: chemicals and compounds Inorganics: metals and elements Other tests: pH, flash point Develop new methods

PresenterPresentation NotesStress our own methods.

Samples to TestDTSC

Enforcement Office of Criminal Investigation Cleanup Safer Consumer Products

Other agencies

Dept. of Consumer Affairs

Types of Samples

Soil, water, waste Consumer products Glass, plastic, metal

Steps in Sample Analysis

Sample receiving

Sample log-in and management

Homogenization and pre-prep

Sample preparation

Instrumental analysis

Results and data interpretation

Report preparation

Sample Pre-Prep Grinding

Sample Pre-Prep Sieving

To particle sizes:9.5 mm, 2.0 mm, 1.0 mm

Sample Preparation Organic Extraction

Liquid-liquid extraction Reflux extraction of solids Solid phase extraction

Extraction Tests for Hazardous Waste Classification

Determine whether a waste is toxic Simulate what happens in a landfill Prep the sample and analyze Determine whether the samples are toxic by comparing to threshold values

Hazardous Waste Classification

US EPA TCLP Toxic Characteristic Leaching Procedure 20-fold dilution, acetic acid, 18 hours shaking test for 7 metals

CA WET Waste Extraction Test 10-fold dilution, citric acid, 48 hours tumbling test for 17 metals

Sample Preparation Inorganic Acid Digestion

PresenterPresentation Notesspecialized

Sample Analysis Instruments

Gas Chromatography

Liquid Chromatography

Inductively Coupled Plasma

X-Ray Fluorescence

Spectrophotometry

GC Chromatogram

Gas Chromatography -Detector

MS, Mass Spectroscopy

FID, Flame Ionization Detector

ECD, Electron Capture Detector

PID, Photo-Ionization Detector

MTBE

Gas Chromatography Mass Spectrometry (GC-MS)

Volatile Organic Compounds (VOCs)

EPA Method 8260

Quality Control Samples

Duplicate

Matrix Spike

Lab Control Sample

MethodBlank

Matrix Spike

Duplicate

Sample Batch

Quantitation

Calibration Curve

y = 102509x + 18101R2 = 0.9975

0

500,000

1,000,000

1,500,000

2,000,000

2,500,000

3,000,000

0 5 10 15 20 25 30

Concentration (ppb)

Inst

rum

ent R

espo

nse

Chart1

99555

500101

1100201

2120500

2523201

Concentration (ppb)

Instrument Response

Calibration Curve

Sheet1

ConcentrationResponse

199,555

5500,101

101,100,201

202,120,500

252,523,201

Sheet1

Concentration (ppb)

Instrument Response

Calibration Curve

Sheet2

Sheet3

Anticipate Needs

Expand the capabilities of the lab, new chemicals and new matrices

Establish new methods through development and validation

Respond to DTSC mandates

PresenterPresentation NotesAnticipating needs?Beyond std methods?

Metals in Glass

Toxics in Packaging Prevention Act California laws to limit cadmium, lead,

mercury, and hexavalent chromium in product packaging

Glass Beads

Metal-Containing Jewelry

Establish and Validate a Method

Research methods Adapt and optimize to the lab Determine calibration range Run Quality Control materials

Method blank, duplicate, matrix spike,laboratory control sample, certified reference material

Special Projects: Waste Stream Studies

Metal Shredder Waste eWaste Alkaline and dry cell batteries Treated wood waste LED lamps Cathode ray tubes

mixture of metal, plastic, glass, wire, resin, rubber, fabric, foam, fiber, fluff, etc.

Our Lab Results Support

Enforcement Citations, fines, penalties Prosecution Settlements

AT&T $52 million Comcast $26 million

Foundation for new regulations

SummaryECL Analytical Chemistry

Sample analysis Develop new methods Special projects

Consultation and support

Department of Toxic Substances Control Cal/EPA

Scientific Leadership:Chemicals of Emerging Concern

Myrto Petreas, Ph.D., MPHChief, Environmental Chemistry Branch

December 9, 2016Environmental Chemistry Laboratory, Berkeley

Dr. June-Soo Park, Biomonitoring Branch Chief

All ECL staff

Acknowledgement

Our history with emerging chemicalsExamples of our workFlame RetardantsFluorinated Chemicals (PFAS)

BiomonitoringUnknown ChemicalsHow our work benefits other DTSC activities

Outline

PresenterPresentation NotesDHS1991