Transcript

TISPORa non-profit 501(c)(3) organization

20 Nassau Street, Suite 307Princeton, NJ 08542 USA Tel: 609-252-1305 Fax: 609-252-1306 email: [email protected] Internet: www.ispor.org

1999-2000 EXECUTIVE BOARD

PresidentBryan Luce PhD, MBAMEDTAP [email protected]

President-ElectJon Clouse RPh, MSIngenix-Kern [email protected]

Past PresidentRobert S. Epstein MD, [email protected]

DirectorsDiana Brixner RPh, [email protected]

Peter Davey MD, [email protected]

Karen Rascati RPh, [email protected]

Adrian Towse MA, [email protected]

Gordon Vanscoy PharmD, [email protected]

Executive DirectorMarilyn Dix Smith RPh, [email protected]

ISPOR NEWS EditorDonna Rindress [email protected]

UNITING SCIENCE AND PRACTICE

VOL. 6, NO. 2 MAR/APR 2000 INTERNATIONAL SOCIETY FOR PHARMACOECONOMICS AND OUTCOMES RESEARCH

IN THISISSUE

Distinguished ISPOR Members Head Up theISPOR Health Science Steering Committee

News

1_ ISPOR’s Health Science Steering Committee

3_ Fireside Chat with ISPOR President Bryan Luce PhD, MPH

4_ ISPOR’s Board of Directors Actions

6_ News Briefs from Around the World

8_ Student Corner

8_ Student Networking Group

9_ Bulletin Board

10_ Using Pharmacoeconomics & Outcomes Research Innovatively

17_ ISPOR 5th Annual International Meeting Events Chart

18_ ISPOR 5th Annual International Meeting Summary of Events

19_ ISPOR 5th Annual International Meeting Registration

The ISPOR Board of Directors recently

approved the formation of the ISPOR Health

Science (HS) Steering Committee. The

objective of this HS Steering Committee is

to build on the initiatives of the multi-

disciplinary Cost-effectiveness in Health and

Medicine Panel appointed by the US Public

Health Service (whose recommendations

were published in Cost-effectiveness in Health

and Medicine, edited by Gold, Siegel, Russell,

and Weinstein), the ISPOR Advisory Panels

on Pharmacoeconomics Issues (whose recom-

mendations were published in VALUE IN

HEALTH Vol. 2, No. 2 [March-April, 1999]),

and other outcomes research practice

standard publications.

The goals of the ISPOR Health SciencePolicy Task Forces are to:

1. Develop and disseminate good practice

standards in health outcomes research and

its use in decision making:

• To address the specific methodological

issues identified for each pharma-

coeconomic / outcomes research

methodology;

• To develop consensus on solutions to

these issues through programming,

surveys, or other means of promotion.

• To publish these results as good research

practices, code of ethics, or policy

statements.

2. Develop other resources for influencing

public healthcare policy.

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3. Influence public healthcare policy-making on the basis of goodscientific practices to improve the use of scientific information(i.e. pharmacoeconomic/health economic and healthcareoutcomes information) in healthcare decision-making and todevelop awareness of these good research practices, code ofethics, or policy statements through programs, workshops, ortraining programs with healthcare decision-makers.

The HS Steering Committee Chair is:Nicolaas Otten PharmD, Director Pharmaceutical & ExtramuralResearch, Canadian Coordinating Office for Health Technology,Ottawa, Ontario, Canada

The HS Steering Committee Task Forcesand Chairs are:Task Force on Good Research Practices – Prospective StudiesLouis A. Morris PhD, Senior Vice President and ManagingDirector of the Marketing and Regulatory Consulting Division ofSCP Communications, Melville, New York, USA

Task Force on Good Research Practices – Modeling StudiesMilton Weinstein PhD, Professor Health Policy & Management,Harvard School of Public Health, Center for Risk Analysis,Boston, Massachusetts, USA

Task Force on Good Research Practices – RetrospectiveDatabase StudiesBrenda Motheral RPh, PhD, MBA, Assistant Professor, Universityof Arizona, College of Pharmacy, Tuscon, Arizona, USA

Task Force on Good Research Practices-Outcomes Assessmentusing Quality of Life IndicatorsPaul Kind Mphil, Senior Research Fellow, University of York,Centre for Health Economics, York, UK

Task Force on Use of Pharmacoeconomic / Health EconomicInformation in Healthcare Decision-makingMichael Drummond PhD, Director, University of York,Centre for Health Economics, York, UK

Task Force on Medical Information AccessKarl Matuszewski MS, PharmD, Director, Technology Assessment, University HealthSystem Consortium, ClinicalPractice Advancement Center, Oak Brook, Illinois, USA

Task Force on Code of EthicsFrank Palumbo JD, PhD, Director, University of Maryland Centeron Drugs & Public Policy, Baltimore, Maryland, USA

Each of the Task Force will have its own agenda, but areascommon to two or more Task Forces will be coordinated throughthe Steering Committee. In particular, we want to develop

comprehensive good research practices (‘toolboxes’) for themajor methodological areas to provide guidance to theresearchers. Second, we would like to develop ‘levels of evidence’or checkboxes for those components that are consideredessential. In some areas, such as use of administrative databases,there is very little in the way of current published good researchpractices. For others, some work has begun (e.g., modeling) fromwhich we can provide further clarification and enhancementwhile others (e.g. quality of life) have been clarified and acceptedin some jurisdictions.

The four Task Forces which will be primarily developing‘toolboxes’ for the outcomes researcher are:• Task Force on Good Research Practices – Prospective Studies• Task Force on Good Research Practices – Modeling Studies• Task Force on Good Research Practices – Retrospective

Database Studies• Task Force on Good Research Practices – Outcomes Assessment

using Quality of Life Indicators

The Task Forces must address the ethical issues to consider whenconducting the types of outcomes research given above, as well asthe issues to address in assuring access to medical information(such as assuring patient confidentiality), are:• Task Force on a Code of Ethics• Task Force on Medical Information Access

The Task Force must act as a ‘two-way’ street to assure that thegood research practices incorporate the needs and ‘reality checks’of healthcare decision-maker and must be the translator of thesegood research practices as well as develop a ‘toolbox’ for thehealthcare decision-maker in interpreting and using outcomesstudies is:• Task Force on Use of Pharmacoeconomic / Health Economic /

Outcomes Research Information in Healthcare Decision-making

The diagram below illustrates the overlap in missions.

continued from cover…

Good ResearchPractices –

Prospective Studies

Good ResearchPractices –

Retrospective Database Studies

Code of Ethics

Medical Info Access

Good Research Practices – QoL

Outcomes Assessment

Good Research Practices –

Modeling Studies

Use of Pharmacoeconomics / Health Economic / Outcomes Research Information

on Healthcare Decision Making

A

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from Bryan Luce PhD, MPH, 1999-2000 ISPOR President

FIRESIDE CHATwith the ISPOR President

Bridging the Gap: AWake-up Call!

The mission of theInternational Society forPharmacoeconomics andOutcomes Research is totranslate pharmacoeconomicsand outcomes research intopractice to ensure that societyallocates health care resourceswisely, fairly and efficiently.

At our Strategic Planning Retreat last

Autumn, the ISPOR Board decided that

its highest priorities for new initiatives

was ‘bridging the gap’ between the

production of health economic and

outcomes research information and the

use of it in health care decision-making.

We have yet to make significant

progress in closing this gap…a term

which may be better labeled ‘chasm’.

The issue was brought to the fore at

Hilton Head earlier this month where I

participated in a session at the annual

DIA Quality of Life conference. My job

was to describe ISPOR’s role and

activities relative to health-related

quality of life. I shared the platform

with Dr. Ivan Borovsky, President-elect

of the International Society of Quality

of Life (ISOQOL) who was to give a

parallel presentation as to his Society’s

role. Without coordinating

presentations, our respective remarks

made obvious that we had very

different views of the roles of our two

societies. According to Dr. Borovsky,

ISOQOL’s role is primarily focused on

technically improving the state of

health-related quality of life (HRQL)

research, while I saw ISPOR as more

focused on the policy of disseminating

and using HRQL information for health

care decision-making. When asked my

opinion as to whether the HRQL

evidence was being used systematically

in health care decisions, I had to answer

that I saw very little evidence of it.

This is both ironic and unfortunate.

Ironic in that health-related quality of

life endpoints are now virtually

standard elements of most major drug

clinical protocols and are increasingly

included as measures of clinical efficacy

and even part of the labeling. Further,

health-related quality of life is almost

purely a patient issue, secondarily a

patient family issue. When patients seek

health care, they seek first and foremost

improvement of their

health status.

Thus, we have a market that is

supplying a good (HRQL information)

which end users (patients) desire.

So, where is the break-down. I believe it

is the intermediaries who are at fault.

This includes the marketers within

manufacturers who may not be

promoting the HRQL message to

patients, the FDA who may be reluctant

to allow the message to be disseminated

to patients and the health care decision

makers themselves who do not seem to

sufficiently value the HRQL messages

that are available.

Unfortunately, the same basic story is

true for the health economics and

outcomes research field as a whole.

Health care decision-making today

does not, in the main, take into account

the full value which drugs and other

health care products and services

deliver to patients, their families, the

health care system, the employer and

society as a whole.

Thus, the wake up call noted above.

The leadership of ISPOR seeks ideas

and volunteers to "bridge the gap".

In keeping with the remarks I made in

Hilton Head and note in this message,

I call on the ISPOR Quality of Life

Special Interest Group (QLSPIG),

ISPOR Managed Care Special Interest

Group, (MCSPIG), and the ISPOR

Disease Management Special Interest

Group (DMSIG) to focus on bridging

this gap and I call on the health

economists, other analysts, educators

and clinicians in the Society to do the

same. If you have ideas and/or time to

volunteer, please join an ISPOR Special

Interest Group via the web at

www.ispor.org under Special Interest

Groups. •

The Board of Directors took thefollowing actions at recent Board ofDirectors Meetings

Board of Directors Meeting, November 14, 1999,Edinburgh, Scotland:1. The Board approved the following goals and objectives

and organizational structure for the ISPOR Health Science

Steering Committee recommended by the Health Policy

Ad Hoc Committee. The ISPOR Health Science Steering

Committee consists of the Health Science (HS) Task Force

Chairs and a member of the Board of Directors. The

objectives of the HS Steering Committee are to establish

goals, timetables, and desired outcomes (deliverables) for

the HS Task Forces and communicate and coordinate

activities between the Task Forces.

1.1. The ISPOR HS Task Forces are: 1) to develop and

disseminate good practice standards in health

outcomes research and its use in decision-making;

2) develop other resources for influencing public

healthcare policy; 3) influence public healthcare

policy-makers to improve the use of scientific

information in healthcare decision-making

1.2. The Task Forces are as follows:

• Task Force On Good Research Practices –

Prospective Studies

• Task Force On Good Research Practices –

Modeling Studies

• Task Force On Good Research Practices –

Retrospective Database Studies

• Task Force On Good Research Practices –

Quality Of Life Studies

• Task Force On Use Of Pharmacoeconomic /

Health Economic Information In Healthcare

Decision-Making

• Task Force On Medical Information Access

• Task Force On A Code Of Ethics

2. The Board requested an analysis of Annual Meeting and

European Conference attendee work environment to assess

ISPOR’s growth characteristics.

3. The Board approved the development of a 3-year ISPOR

Business Plan. The ISPOR Business Ad Hoc Committee is

composed of Jon Clouse (Chair), Diana Brixner, Rob

Epstein, Jean Paul Gagnon, and Adrian Towse.

4. The 2000 ISPOR Budget with modification was approved.

5. The Board approved the Finance Committee policy

recommendations on meeting press passes, complimentary

and one-day Annual Meeting and European Conference

registrations and leadership travel reimbursement policy.

6. The Board approved the new composition of the Finance

Committee (Treasurer, as chair, President-elect, and a

Director appointed by the Board).

7. The Board approved the membership fee to be increased

from $125 to $135 to cover the increase in VALUE IN

HEALTH publication expenses for 2000.

Board of Directors’ Meeting, February 8, 2000(Teleconference):1. The Board approved that PhRMA Foundation Faculty

Development Awards in Pharmacoeconomics be presented

at the ISPOR Annual Meeting.

2. The Board approved ISPOR as a co-sponsor for the

following events as a non-revenue / non-risk-sharing

sponsor: International & Research: Society for

Pharmacoepidemiology’s Health Care Databases A

symposium on the Power and Perils of Health Data used

In Epidemiologic and Economic Research April 14, 2000,

Chapel Hill, NC; and the European Association of Clinical

Pharmacologists and Therapeutics’ Meeting, September

12-14 2001. Based on previous Board action, non-

revenue/non risk sharing co-sponsorship can include the

use of the ISPOR name and logo and displaying event

brochures at an ISPOR Meeting at no cost; announcement

of the event in the ISPOR NEWS at the prevailing rate;

mailing an event brochure to ISPOR members at the

prevailing mailing list rate.

3. The Board approved the following description, criteria,

selection process, and nature of award for the ISPOR

Research Award for Methodology Excellence and ISPOR

Research Award for Practical Application Excellence as

recommended by the Awards Committee.

ISPOR Board of Directors Actions

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1999-2000 Executive BoardFrom left to right, Peter Davey MD, FRCP, University of Dundee; Jon Clouse

RPh, MS, Ingenix-Kern McNeil; Robert S. Epstein MD, MS, Merck-Medco

Managed Care, LLC; Diana Brixner RPh, PhD, Novartis Pharmaceuticals

Corporation; Bryan Luce PhD, MBA, MEDTAP International; Adrian Towse

MA, Mphil, Office of Health Economics; Jean Paul Gagnon PhD, Hoechst

Marion Roussel, Inc; Karen Rascati RPh, PhD, University of Texas

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ISPOR Research Award for Methodology ExcellenceDESCRIPTION:

The ISPOR Research Excellence Award for Methodology Excellence was established in 1997 to recognize outstanding

research in the field of pharmacoeconomics and outcomes research methodology.

CRITERIA: The winner of ISPOR Research Excellence Award for Methodology Excellence is selected by the Awards Committee

based upon publications that have appeared in respected peer-review journals and other communication venues

(e.g., books, reports) during the preceding eighteen months from January 1 of the year awarded. The award selection is

based upon the publication’s clear description of methods, along with the appropriate and creative applications

(or proposal thereof in conceptual methodology work) of techniques to answer important questions in the field of

pharmacoeconomics and outcomes research. Such publications will be expected to have much impact on the field, due

to their acceptance and application by others.

SELECTION PROCESS:A call for nominations is placed in November-December ISPOR NEWS for articles published during the past eighteen

months to be considered for the ISPOR Research Excellence Award for Methodology Excellence. In addition, each

Awards Committee member selects relevant publications in respected peer-reviewed journals during the preceding

eighteen months to be considered by the Awards Committee in the selection process. The Awards Committee meets via

teleconference in February to discuss each of the nominated publications. They select the best demonstration of

scientific excellence for that time period. The senior author on the publication is given the award.

NATURE OF AWARD:The Award, presented at the ISPOR Annual International meeting, consists of a plaque, complimentary Annual

International Meeting registration, roundtrip air fare, hotel, meal and miscellaneous expenses for two days, based upon

current ISPOR travel policies.

ISPOR Research Award for Practical Application ExcellenceDESCRIPTION:

The ISPOR Excellence Award for Practical Application Excellence was established in 1997 to recognize outstanding

practical application of pharmacoeconomics and outcomes research in healthcare decision-making.

CRITERIA: The winner of ISPOR Research Excellence Award in Practical Application Excellence is selected by the Awards

Committee based upon publications that have appeared in respected peer-review journals or other communication

venues (e.g., guidelines, reports, books) during the preceding eighteen months from January 1 of the year awarded.

The award selection is based upon the article's clear description of methods, along with the appropriate and creative

applications of techniques to answer important questions in the field of pharmacoeconomics and outcomes research.

Such publications will be expected to have much impact on the field, due to their acceptance and wide-spread use.

SELECTION PROCESS:A call for nominations is placed in November-December ISPOR NEWS for articles published during the past eighteen

months to be considered for the ISPOR Research Excellence Award for Application Excellence. In addition, each Awards

Committee member selects relevant publications in respected peer-reviewed journals during the preceding eighteen

months to be considered by the Awards Committee in the selection process. The Awards Committee meets via

teleconference in February to discuss each of the nominated publications. They select the best demonstration of

scientific excellence for that time period. The senior author on the publication is given the award.

NATURE OF AWARD:The Award, presented at the ISPOR Annual International meeting, consists of a plaque, complimentary Annual

International Meeting registration, roundtrip air fare, hotel, meal and miscellaneous expenses for two days, based upon

current ISPOR travel policies.

NEUROPENew EC regulations offering financialincentives to companies that developproducts for rare diseases came into forceat the end of January. A budget forfunding should be established byFebruary. (Scrip 2509:3) ■ The head of theEC Commission’s pharmaceuticals andcosmetics unit has called for thedevelopment of guidelines on goodregulatory practice as the EU prepares toadmit new members. EU expansion isforcing regulators to consider how tobalance various marketing, confidentialityand transparency issues. (Scrip 2513:2) ■ According to the Pan-EuropeanRegulatory Forum on Pharmaceuticals(PERF), all regulatory agencies shouldattempt to keep scientific assessments freeof political influences despite the lack ofan organizational model. (Scrip 2514:5) ■ The EC Commission may extendEudraNet, its electronic network forpharmaceutical data, to countriesnegotiating to enter the EU. The networkallows for the rapid transmission of databetween regulatory authorities.(Scrip2515:5)

CroatiaChronic healthcare fund shortages haveresulted in payment delays that arethreatening medicine supplies. Croatia’slargest wholesaler is reportedly owedDM128 million ($64.6 million) by the statehealth insurance agency. (Scrip 2519:7)

CzechoslovakiaThe lower chamber of the CzechParliament has rejected a proposal toinclude a "Roche-Bolar" provision innational patent legislation. The decisionwas influenced by the current EUchallenge of similar legislation in Canada.(Scrip 2521:3)

FrancePharmaceutical spending remains resistantto government cost-containmentmeasures. CNAM, the health insurancebody, suggests that a number of delistingscould be imminent. (Scrip 2516:2)

GermanyKrankenkassen pharmaceutical spendingreached DM35.1 billion ($18.2 billion) in

1999, 4% over the budget ceiling and 7%more than 1998. As a basis for furtherreform, the health ministry is looking atthe therapeutic added value of "me-too"products and encouraging the use ofgenerics. (Scrip 2512:3) ■ The HealthMinistry expects to implement anamendment to the negative listwithin a few months. Theamendment contains about400 products deemed tobe uneconomic interms of efficacy orformulation. (Scrip2519:3)

HungaryThe government isproposing legislationthat would increase the share of totalreimbursement given to generics to at least35% from the current 21%. The legislationis an attempt to cut spending inpreparation for EU entry in 2003. (Scrip2517:6)

ItalyAfter its first major overhaul, Italy’sreimbursement list will more closelyresemble an aid to prescribing completewith a list of generics, cost comparisonsand prescribing restrictions. The firstedition should be available this July.(Scrip 2512:8)

NorwayNorway is the latest European country topublish pharmacoeconomic guidelines.Companies are being asked to use the newguidelines for preparing cost-effectivenessdata for their products. (Scrip 2522:6)

PortugalThe Health Minister has suspended a 6-month review and called for a re-evaluation of plans by Infarmed (thepharmacy and medicines institute) to limitOTC ingredients. Under Infarmed’s planmany currently available OTC items wouldbecome prescription only. (Scrip 2512:6) Russia: The Russian pharmaceutical market isexpected to grow by 5% because of anincrease in the population’s disposableincome. The market is currently valued at$1.9 billion. (Scrip 2509:5)

SpainThe Spanish government expects that theintroduction of reference pricing willpromote the use of generics and helpcontain spending in 2000. Spending onpharmaceuticals is currently 25% of thehealthcare budget. (Scrip 2509:5) ■ Spanish generic manufacturers claim thegovernment is not adequately supportinggenerics, citing the implementation of lastyear’s 6% general price reduction on allpharmaceuticals. As of mid-January 351generics were approved for use in Spain.(Scrip 2517:3) ■ A Spanish court has ruledthat additional payments demanded by theHealth Ministry from the pharmaceuticalindustry may be suspended until theirlegality is assessed. The government askedfor the payment when pharmaceuticalspending rose above levels set in anagreement with industry. (Scrip 2521:2)

UKThe National Audit Office is to endorseplans to combine antibiotic prescribinginformation with data on hospitalacquired infection. Proper infectioncontrol could reduce infections by 15%leading to savings of £150 million. (Scrip2519:4) ■ Patient groups are lobbying thegovernment for wider prescribing ofinnovative but costly pharmaceuticals.Several such drugs are currently underreview by the National Institute forClinical Excellence (NICE). (Scrip 2523:2)■ As part of a plan to modernize the

News Briefs from around the World

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National Health Service (NHS), thegovernment has decided to expand the range of drugs that nurses canprescribe. Specialist nurses are expected to be the first to gain the new authority.(Scrip 2523:3)

AFRICASouth AfricaThe Constitutional Court has thrown out South Africa’s medicines act. The actrepealed all of the country’s previouspharmaceutical legislation but was passedbefore necessary regulations, regulatorystructures and medicines schedules wereput in place. (Scrip 2522:19)

ASIAAustraliaThe government’s new National MedicinesPolicy encourages all levels of governmentto work together with health professionals,educators, the medicines industry,consumers and the media to ensure thatpatients have timely and cost-efficientaccess to safe, high quality medicines.The report also recommends theimplementation of a nationallystandardized, rational and transparentregulatory process. (Scrip 2515:17)

ChinaProvincial authorities are continuing toimplement price controls in an effort tocurb pharmaceutical spending in state-runinsurance schemes. Overall price cuts of10% are expected to save Yuan 3.2 billion.(Scrip 2513:17; 2514:15) ■ The State DrugAdministration (SDA) has issued newregulations for contract manufacture ofpharmaceuticals. Companies must getprior SDA approval before transferringproduction or outsourcing to externalcompanies. (Scrip 2515:18) ■ Citing safetyconcerns, China has banned all Internettrade of pharmaceuticals. (Scrip 2517:16)Malaysia: ■ The Health Ministry hasintroduced a new national essential druglist. Compliance is voluntary and as yet itis uncertain if the list will replaceMalaysia’s Blue Book. (Scrip 2514:17)New Zealand: ■ The Ministry of Healthhas asked the government to revise theMedicines Act to allow prosecution forsupplying medicines via the Internetwithout prescriptions. Pharmaceuticalsales through local web sites in 1999 were

estimated at NZ$50 million ($25 millionUS). (Scrip 2519:21)

PhilippinesThe pharmaceutical sector faces an uphillstruggle against political and publicpressure to reduce prescription productprices. The industry denies overchargingand claims that net profits are only 5-15%of net sales. (Scrip 2510:17)

South KoreaThe government has established guidelinesfor determining equivalence andbioavailability of products thatpharmacists will be allowed to substitute.Doctors are continuing their opposition tothe split of prescribing and dispensingsince many rely on the dispensing marginfor income. (Scrip 2523:19)

VietnamThe government is looking at a range ofmeasures to increase foreign investment inthe pharmaceutical sector. The recentprivatization of two state-ownedpharmaceutical companies has generatedstrong investor interest. (Scrip 2509:16)

THE AMERICASBrazilThe Brazilian National HealthcareMonitoring Agency (ANVS) has issued thefirst marketing authorization for generics.Generics will be priced 30-55% cheaperthan branded products. ANVS is alsodrafting new legislation to governpharmaceutical advertising and to prohibitsampling. (Scrip 2514:17) ■ The HealthMinistry wants to change its tenderingprocess for medicines purchases by settingup a price register to encouragetransparent competition and make iteasier for public purchasers to obtainmedicines at low prices. The governmentis proposing that pharmaceutical supplierscompete to be included on the register.(Scrip 2517:14)

CanadaThe World Trade Organization (WTO) has made an interim ruling againstCanada in a recent patent dispute. Theruling says Canada should grant 20-yearpatents to all patents existing as of January1st 1999. (Scrip 2521:16) ■ The CanadianPharmaceutical Association (CPhA) hascalled for the suspension of the personalinformation protection and electronicdocuments act as it relates to health.

According to the CphA, patients coveredby public and private health plans will betreated differently leading to higher costsfor pharmacists. (Impact 10 no.1:2)

USAOnline pharmaceutical sales are expectedto dominate health e-commerce by 2004,accounting for $15 billion. Doctors areexpected to be a key factor in this growthas the number of prescriptions writtenelectronically increases. (Scrip 2509:15) ■ President Clinton is calling for theprovision of affordable drug coverage forthe elderly. The pharmaceutical industry isafraid that a government-run programmight slow down R&D because of theimposition of price controls. (Scrip2510:15) ■ President Clinton has addedcatastrophic coverage to the Medicaredrug benefit he proposed last year.(Scrip2513) ■ The FDA has been given ayear to develop new standards for theprevention of medical errors arising fromconfusion over proprietary drug namesand packaging. The Institute of Medicine(IOM) estimates indicate that between44,000 and 98,000 deaths per year resultfrom preventable medical errors. (Scrip2517:13; Managed Healthcare News 16no.2:13)

THE WORLDThe WTO has reached an interimagreement in the EU/Canada patentdispute. The WTO has decided againstallowing Canada to retain its stockpilingprovision under which products aremanufactured and stockpiled 6 monthsprior to patent expiry. (Scrip 2511:14) ■

The WHO is offering to organize a jointworking group with the WTO to studyaccess to essential medicines. IFPMA, theinternational pharmaceutical industryassociation, questions the need for thegroup since discussions are alreadyunderway between the WHO and industryrepresentatives. (Scrip 2514:16) ■

Pharmaceutical sales in the 12 leadingworld markets grew by 10% in 1999.Growth rates were driven by particularlystrong performances in the US andCanada. (Scrip 2518:17) •

M8

Student Corner

A message from Mohamed Omar MS RPh,Outgoing Chair of the ISPOR StudentNetworkMy interest in creating a formal structure for students at ISPORbegan with the creation of the first student chapter at the Universityof Texas in July 1998. I envisioned a student chapter of ISPOR atevery academic institution in the country that offers a program inpharmacoeconomics and/or health outcomes research. Since thattime, three more student chapters have been established at theUniversities of Arizona, Toronto and Louisiana at Monroe. Inaddition, the ISPOR Student Network (SN) that comprises morethan 180 student members has been established, as well as theISPOR Student Council whose members include the Presidents ofthe student chapters and the Student Advisor.

The objectives of the SN are very much parallel to those of theparent organization. The network provides a forum for the exchangeof information and the delivery of programs designed specifically forthe benefit of the student membership of ISPOR. As the leader of

this network, I have had the opportunityto represent students at the ISPORStrategic Planning Retreats regardingvarious issues such as those pertaining toeducation, fellowships, annual meetings,and career launching. Currently,members of the Student Council andmyself are working on establishing anemail-mentoring program for studentsthat will link each ISPOR student with a working member of ISPOR.We hope that this program will empower students to get a head starton utilizing the networking resources of professionals in the field.

My experiences in serving as the voice of students of ISPOR studentshave been very rewarding indeed. In the process of helping set thefoundation for students, I’ve learned the dynamics of a largeprofessional organization. I hope to carry this understanding withme to serve other areas of ISPOR. Finally, my endeavors have beensuccessful primarily because of the support I have received from theISPOR Board of Directors, who have continuously recognized thevalue of the student membership.

Student Networking Group

Mohamed Omar RPh, MS,1999-2000 Student Networkand Student Council Chairand Student NetworkFounderGraduate StudentUniversity of Texas at AustinE-mail:[email protected]

Veronica Sendersky PharmD,1999-2000 Student NetworkChair-electGraduate StudentUCLA School of Public PolicyE-mail:[email protected]

Deirdre Monroe RPh, MBA,President ISPOR StudentChapter – University of Texasat AustinDoctoral CandidateUniversity of Texas at AustinE-mail: [email protected]

Thomas Delate MS, PresidentISPOR Student Chapter-University of ArizonaHealth Outcomes FellowUniversity of ArizonaE-mail:[email protected]

Ateequr Rahman MBA,President ISPOR StudentChapter – University ofLousiana at MonroeGraduate StudentUniversity of Lousiana at MonroeE-mail: [email protected]

Kostas Trakas MSc, PresidentISPOR Student Chapter –University of TorontoGraduate StudentUniversity of TorontoE-mail:[email protected]

Zeba Khan MS,PhD, ISPORStudent AdvisorSenior Health OutcomesScientistGlaxo Wellcome Inc.US Medical Affairs,Health OutcomesE-mail:[email protected]

ISPOR STUDENT COUNCILThe Board recently approved the organizational structure of the

ISPOR Student Council. The ISPOR Student Council is composed

of the ISPOR Student Networking Chair and chair-elect, the

Presidents of the ISPOR Student Chapters, and the Student

Advisor. The Council meets about once a month via teleconference

to discuss topics of interest to ISPOR students. The ISPOR Student

Network Chair chairs the Student Council.

ELECTION OF ISPOR 2000-2001 ISPORSTUDENT NETWORK CHAIRIn the January and February ISPOR STUDENT NETWORK

BULLETINs, nominations for 2000-2001 ISPOR Student Network

Chair were requested. Veronica Sendersky PharmD, a graduate

student at UCLA School of Public Policy is now the Chair-elect of

the ISPOR Student Network Group. Veronica will join the other

members of the ISPOR Student Council and will represent the

students at the ISPOR Leadership Retreat 2000.

1999-2000 ISPOR STUDENT COUNCIL

I

IVeronica Sendersky, to be new Chair of the Student NetworkI would like to introduce myself to you. My name is Veronica

Sendersky. I am currently pursuing a Master of Public Policy

degree at UCLA, specializing in Health Economics and Policy.

I received my PharmD degree last year. I have been very active in

professional organizations. I was elected to represent my

pharmacy class on the board of the Academy of Students of

Pharmacy (ASP). My biggest achievement as ASP officer was a drastic increase in the

membership. I was able to increase the number of members in our class by about 100%

by initiating an early membership drive. I am very excited about being the new chair of

the Student Network, and look forward to my new responsibilities.

Veronica Sendersky can be reached at [email protected]

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ISPOR STUDENT RECEIVES TOPHONORS AT DIA EUROMEETINGMr. Sanjay Merchant, DoctoralCandidate at the University ofMaryland, School of Pharmacy, wasawarded top honors for his posterpresentation at the 12th Annual DIAEuroMeeting held in Nice, France,March 2000.

Title: Impact of Illness Severity onCost of Community AcquiredPneumonia Patients.

Authors: Sanjay Merchant, C DanielMullins, and Catherine Cooke.

The Carnegie FoundationHonors UA College ofPharmacy Professor;JoLaine R. Draugalis, PhD,Appointed to Serve withElite Scholars Group

JoLaine R. Draugalis, PhD, professorand assistant dean at the University ofArizona College of Pharmacy, hasbeen named a 2000-2001 CarnegieScholar by the Carnegie Academy forthe Scholarship of Teaching andLearning. Dr. Draugalis is one of 40outstanding faculty chosennationwide, who will work together toinvent and share new conceptualmodels for teaching.

Much more than an honorary title,Dr. Draugalis’ research interestsinclude pharmacy education, programdesign, administration and evaluation,as well as educational applications inpharmacoeconomics. She joined theCollege faculty in 1989, teachingDoctor of Pharmacy students andparticipating in several graduate-levelcourses. She received the BasicScience Pharmacy Educator of theYear Award from the College in 1990,1992, 1994 and 1997 and was namedthe Distinguished Pharmacy Educatorby the American Association ofColleges of Pharmacy in 1998.

A few words from the ISPOR StudentNetwork Advisor, Zeba M Khan PhDI am very proud and honored to serve as your ISPOR Student

Network Advisor. I would first like to thank the ISPOR Board

of Directors, especially Dr. Marilyn Dix Smith, for their

support with the Student Network (SN). Special thanks to

Mohamed Omar for his hard work in establishing and

coordinating the SN.

As your ISPOR Student Network Advisor, I will do my best to coordinate network

activities and provide assistance in planning for long-term goals for the SN. Now, all

current ISPOR students are members of the SN. However, if you would like your name

to appear in the ISPOR Student Network Directory, you must complete the form at the

ISPOR website (www.ispor.org)>>Members Only>>Student Corner.

I also encourage you to join us at the ISPOR Student Forum which will be held Tuesday,

May 23rd, 5:30 to 7:30 PM and the Student Reception from 7:30 to 9:30 PM at the

ISPOR 5th Annual International Meeting at the Crystal Gateway Marriott in Arlington,

VA. By attending, you will learn about the established ISPOR Student Chapters, and will

be able to network with other students and ISPOR members. The program also includes

Student Awards and two guest presentations.

I encourage those students not currently involved with ISPOR to become involved by

contacting one of the members of the ISPOR Student Council. This includes the

Presidents of the student chapters and the Student Advisor. We currently have over 180

student members and would like to see this number grow by establishing a student

chapter in every institution that offers programs in pharmacoeconomics or health

outcomes research. I strongly encourage students and ISPOR members to get involved in

the email-mentoring program once it is established. This will be a great opportunity for

students and other members to interact.

By working together, I am confident we can establish a strong ISPOR Student Network

that will be beneficial to everyone. Your involvement and participation are key to a

successful year.

Zeba Khan can be reached by email at [email protected], or

by telephone at (919) 483-7999

10

BioMedCom Consultants inc.

prepared this column from a

survey of the biomedical and

healthcare literature; it

includes books, articles and

abstracts recently published

by ISPOR members. To ensure

that your published work in

pharmacoeconomic or

outcomes research is

reported here, please keep

your contact information up

to date with the Society.

You may also submit reprints

directly for inclusion in

future columns. Any

questions or comments

concerning this review can

be directed to BMC by

telephone: (514) 745-0915,

fax: (514) 745-0916 or e-mail:

[email protected]

Using pharmacoeconomics and outcomes research innovatively

DISEASE RELATEDRESEARCHCardiovascular disease:

• Becker ER, Morris DC, Culler SD,

Mauldin, PD, Shaw LJ, Talley JD,

Weintraub WS. The changing

healthcare market and how it has

influenced the treatment of

cardiovascular disease--Part 1.

American Journal of Managed Care.

5(9):1119-1124, 1999.

• Caro JJ, Huybrechts KF. Stroke

treatment economic model (STEM):

predicting long-term costs from

functional status. Stroke. 30(12):2574-

2579, 1999.

• Dasbach EJ, Rich MW, Segal R, Gerth

WC, Carides GW, Cook JR, Murray JF,

Snavely DB, Pitt B. The cost-

effectiveness of losartan versus

captopril in patients with symp-

tomatic heart failure. Cardiology.

91(3):189-194, 1999.

• Freed LA, Levy D, Levine RA, Larson

MG, Evans JC, Fuller DL, Lehman B,

Benjamin EJ. Prevalence and clinical

outcome of mitral-valve prolapse.

New England Journal of Medicine.

341(1):1-7, 1999.

• Hillert B, Remonte S, Rodgers G,

Yancy CW, Kaul AF. Improving

patient outcomes by pooling

resources (The Texas Heart Care

Partnership Experience). Am J

Cardiol;85:43a-51a, 2000.

• LaBresh KA, Owen P, Alteri C, Reilly

S, Albright PS, Hordes AR, Shaftel PA,

Noonan TE, Stoukides CA, Kaul AF.

Secondary prevention in a cardiology

group practice and hospital setting

after a heart-care initiative. Am J

Cardiol;85:23a-29a, 2000.

• Nelsen LM, Himmelberger DU,

Morrison A, Berger ML, Markson LE.

Quality-of-life questionnaire for

patients taking antihypertensive

medication. Clinical Therapeutics.

21(10):1771-1787, 1999.

• O'Connor CM, Radensky PW, Unger

AN, Martin BC. Hospital use and

costs among patients with

nonischemic cardiomyopathy in the

first prospective randomized

amlodipine survival evaluation study.

Clinical Therapeutics. 21(7):1254-

1265, 1999.

• Weintraub WS, Culler S, Boccuzzi SJ,

Cook JR, Kosinski, AS, Cohen DJ,

Burnette J. Economic impact of

GPIIB/IIIA blockade after high-risk

angioplasty: results from the

RESTORE trial. Randomized Efficacy

Study of Tirofiban for Outcomes and

Restenosis. Journal of the American

College of Cardiology. 34(4):1061-

1066, 1999.

• Zachry WM, Wilson JP, Lawson KA,

Koeller, JM. Procedure costs and

outcomes associated with

pharmacologic management of

peripheral arterial disease in the

Department of Defense. Clinical

Therapeutics. 21(8):1358-1369, 1999.

Endocrinology, metabolism anddiabetes:

• Amin SP, Mullins CD, Duncan BS,

Blandford L. Direct health care costs

for treatment of diabetes mellitus and

hypertension in an IPA-group-model

HMO. American Journal of Health-

System Pharmacy. 56(15):1515-

1520, 1999.

• Baran RW, Crumlish K, Patterson H,

Shaw J, Erwin WG, Wylie JD, Duong

P. Improving outcomes of

community-dwelling older patients

with diabetes through pharmacist

counseling. American Journal of

Health-System Pharmacy.

56(15):1535-1539, 1999.

• Pronk NP, Tan AW, O'Connor P.

Obesity, fitness, willingness to

communicate and health care costs.

Medicine & Science in Sports &

Exercise. 31(11):1535-1543, 1999.

• Thompson D, Edelsberg J, Colditz GA,

Bird AP, Oster G. Lifetime health and

economic consequences of obesity.

Archives of Internal Medicine.

159(18):2177-2183, 1999.

Gastroenterology:

• Chen SY, Wang JY, Chen J, Zhang XD,

Zhang SS. Assessment of decisions in

the treatment of Helicobacter pylori-

related duodenal ulcer: a cost-

effectiveness study. Journal of

Gastroenterology & Hepatology.

14(10):977-983, 1999.

• Enck P, Dubois D, Marquis P. Quality

of life in patients with upper

gastrointestinal symptoms: results from

the Domestic/International

Gastroenterology Surveillance Study

(DIGEST). Scandinavian Journal of

Gastroenterology - Supplement.

231(48-54, 1999.

• Haycox A, Einarson T, Eggleston A.

The health economic impact of upper

gastrointestinal symptoms in the

general population: results from the

Domestic/International

Gastroenterology Surveillance Study

(DIGEST). Scandinavian Journal of

Gastroenterology - Supplement.

231(38-47, 1999.

• Kaplan-Machlis B, Spiegler GE, Revicki

DA. Health-related quality of life in

primary care patients with gastro-

esophageal reflux disease. Annals of

Pharmacotherapy. 33(10):1032-1036,

1999.

• Zhao SZ, Arguelles LM, Dedhiya SD,

Morgan DG. Healthcare utilization

associated with dyspepsia in patients

with arthritis. American Journal of

Managed Care. 5(10):1285-1295, 1999.

Infectious disease:

• Badia X, Podzamczer D, Garcia M,

Lopez-Lavid CC, Consiglio E. A

randomized study comparing

instruments for measuring health-

related quality of life in HIV-infected

patients. Spanish MOS-HIV and

MQOL-HIV Validation Group. Medical

Outcomes Study HIV Health Survey.

AIDS. 13(13):1727-1735, 1999.

• Davey P, Craig AM, Hau C, Malek M.

Cost-effectiveness of prophylactic nasal

mupirocin in patients undergoing

peritoneal dialysis based on a

randomized, placebo-controlled trial.

Journal of Antimicrobial

Chemotherapy. 43(1):105-112, 1999.

• Davey P. Cost effectiveness of

quinolones in hospitals and the

community. Drugs. 58 (Suppl 2)

71-77, 1999.

• Day D, Lubowski TJ, Yamaga CC,

Main J, Van Vleet J, Ambegaonkar A.

Computer-assisted evaluation of

antibiotic regimen coverage and cost.

Clinical Therapeutics. 21(8):1418-1425,

1999.

• Muller E, Berger K, Dennemark N,

Oleen-Burkey M. Cost of bacterial

vaginosis in pregnancy. Decision

analysis and cost evaluation of a

clinical study in Germany. Journal

of Reproductive Medicine. 44(9):

807-814, 1999.

• Paladino JA. Pharmacoeconomics of

antimicrobial therapy. American

Journal of Health-System Pharmacy.

56(Suppl 3):S25-S28, 1999.

• Rifenburg RP, Paladino JA, Bhavnani

SM, Haese DD, Schentag JJ. Influence

of fluoroquinolone purchasing patterns

on antimicrobial expenditures and

Pseudomonas aeruginosa susceptibility.

American Journal of Health-System

Pharmacy. 56(21):2217-2223, 1999.

• Szucs TD. Influenza. The role of

burden-of-illness research.

Pharmacoeconomics. 16 (Suppl 1)

27-32, 1999.

Neurology and mental health:

• Beusterien KM, Rogers AE, Walsleben

JA, Emsellem HA, Reblando JA, Wang

L, Goswami M, Steinwald B. Health-

related quality of life effects of

modafinil for treatment of narcolepsy.

Sleep. 22(6):757-765, 1999.

• Cohen JA, Beall D, Beck A, Rawlings J,

Batenhorst. Sumatriptan treatment for

migraine in a health maintenance

organization: economic, humanistic,

and clinical outcomes. Clinical

Therapeutics. 21(Jan):190-204, 1999.

• Menzin J, Lang K, Friedman M,

Neumann P, Cummings JL. The

economic cost of Alzheimer's disease

and related dementias to the California

Medicaid program ("Medi-Cal") in

1995. American Journal of Geriatric

Psychiatry. 7(4):300-308, 1999.

• Rice GP, Oger J, Duquette P, Francis

GS, Belanger M, Laplante S, Grenier JF.

Treatment with interferon beta-1b

improves quality of life in multiple

sclerosis. Canadian Journal of

Neurological Sciences. 26(4):

276-282, 1999.

• Trobe JD, Sieving PC, Guire KE,

Fendrick AM. The impact of the optic

neuritis treatment trial on the practices

of ophthalmologists and neurologists.

Ophthalmology. 106(11):2047-2053,

1999.

Obstetrics and Gynecology:

• Morlock RJ, Elston Lafata J, Eisenstein

D. Cost-effectiveness of single-dose

methotrexate compared with

laparoscopic treatment of ectopic

pregnancy. Obstetrics and

Gynecology;95(3):407-412, 2000.

Oncology:

• Bonomi AE, Ajax M, Shikiar R,

Halpern M. Cancer pain management:

barriers, trends, and the role of

pharmacists. Journal of the American

Pharmaceutical Association. 39(4):558-

566, 1999.

• Gerbase MW, Dubois D, Rothmeier C,

Spiliopoulos A, Wunderli W, Nicod LP.

Costs and outcomes of prolonged

cytomegalovirus prophylaxis to cover

the enhanced immunosuppression ▼

11

12

phase following lung transplantation.

Chest. 116(5):1265-1272, 1999.

• Hrung JM, Langlotz CP, Orel SG,

Fox KR, Schnall MD, Schwartz JS.

Cost-effectiveness of MR imaging and

core-needle biopsy in the preoperative

work-up of suspicious breast lesions.

Radiology. 213(1):39-49, 1999.

• Jones R, Pearson J, McGregor S, Cawsey

AJ, Barrett A, Craig N, Atkinson JM,

Gilmour WH, McEwen J. Randomised

trial of personalised computer based

information for cancer patients. BMJ.

319(7219):1241-1247, 1999.

Prevention:

• Johnston K, Brown J. Two view

mammography at incident screens: cost

effectiveness analysis of policy options.

BMJ. 319(7217):1097-1102, 1999.

• Saywell RMJ, Champion VL, Skinner

CS, McQuillen D, Martin D, Maraj M.

Cost-effectiveness comparison of five

interventions to increase mam-

mography screening. Preventive

Medicine. 29(5):374-382, 1999.

Respiratory disorders:

• Gleason PP, Meehan TP, Fine JM,

Galusha DH, Fine MJ. Associations

between initial antimicrobial therapy

and medical outcomes for hospitalized

elderly patients with pneumonia.

Archives of Internal Medicine.

159(21):2562-2572, 1999.

• Howard KB, Blumenschein K, Rapp RP.

Azithromycin versus erythromycin for

community-acquired pneumonia: a

cost-minimization analysis. American

Journal of Health-System Pharmacy.

56(15):1521-1524, 1999.

• Kradjan WA, Schulz R, Christensen DB,

Stergachis A, Sullivan S, Fullerton DS,

Sturm L, Schneider G. Patients'

perceived benefit from and satisfaction

with asthma-related pharmacy services.

Journal of the American Pharma-

ceutical Association. 39(5):658-666,

1999.

• Langley PC. Technology of metered

dose inhalers and treatment costs in

asthma: retrospective study of breath

actuation versus traditional press-and-

breathe inhalers. Clinical Therapeutics.

21(Jan):236-253, 1999.

• Palmer CS, Niparko JK, Wyatt JR,

Rothman M, de L. A prospective study

of the cost-utility of the multichannel

cochlear implant. Archives of

Otolaryngology -- Head & Neck

Surgery. 125(11):1221-1228, 1999.

• Ricard N, Kind P, Christian S, Jensen

M, Stewart J. Link between patient

preferences and treatment outcomes in

seasonal allergic rhinitis: empiric

investigation. Clinical Therapeutics.

21(Jan):268-277, 1999.

• Von Behren J, Kreutzer R, Smith D.

Asthma hospitalization trends in

California, 1983-1996. Journal of

Asthma. 36(7):575-582, 1999.

• Matuszewski K, Velayudhan P, Flint N,

Pierpaoli P. Noncompliance with drug

therapy for chronic obstructive

pulmonary disease: a risk factor for

hospitalization? VALUE IN HEALTH.

2(6):446-51, 1999.

Rheumatology and musculoskeletaldiseases:

• Abbott TA, Mucha L, Manfredonia D,

Schwartz EN, Berger ML. Efficient

patient identification strategies for

women with osteoporosis. Journal of

Clinical Densitometry. 2(3):223-230,

1999.

• Melhorn JM, Wilkinson L, Gardner P,

Horst WD, Silkey B. An outcomes study

of an occupational medicine

intervention program for the reduction

of musculoskeletal disorders and

cumulative trauma disorders in the

workplace. Journal of Occupational &

Environmental Medicine. 41(10):833-

846, 1999.

• Strand V, Tugwell P, Bombardier C,

Maetzel A, Crawford, Dorrier C,

Thompson A, Wells G. Function and

health-related quality of life: results

from a randomized controlled trial of

leflunomide versus methotrexate or

placebo in patients with active

rheumatoid arthritis. Leflunomide

Rheumatoid Arthritis Investigators

Group. Arthritis & Rheumatism.

42(9):1870-1878, 1999.

• Zhao SZ, Dedhiya SD, Bocanegra TS,

Fort JG, Rush, SM. Health-related

quality of life effects of oxaprozin and

nabumetone in patients with

osteoarthritis of the knee. Clinical

Therapeutics. 21(Jan):205-217, 1999.

• Zhao SZ, McMillen JI, Markenson JA,

Dedhiya SD, Zhao WW, Osterhaus JT,

Yu SS. Evaluation of the functional

status aspects of health-related quality

of life of patients with osteoarthritis

treated with celecoxib. Pharma-

cotherapy. 19(11):1269-1278, 1999.

Transplantation:

• Schnitzler MA, Hollenbeak CS, Cohen

DS, Woodward RS, Lowell JA, Singer

GG, Tesi RJ, Howard TK,

Mohanakumar T, Brennan DC. The

economic implications of HLA

matching in cadaveric renal

transplantation. New England Journal

of Medicine. 341(19):1440-1446, 1999.

Urology:

• Huang X, Hartzema AG, Raasch RH,

Kauf TL, Norwood GJ. Economic

assessment of three antimicrobial

therapies for uncomplicated urinary

tract infection in women. Clinical

Therapeutics. 21(9):1578-1588, 1999.

• Liu GG, Nguyen T, Nichol MB. An

economic analysis of antimicrobial

prophylaxis against urinary tract

infection in patients undergoing

transurethral resection of the prostate.

Clinical Therapeutics. 21(9):1589-

1604, 1999.

TOPICS OF GENERALINTERESTHealth Policy and Decision-making:

• Johnson N. Future of outcomes

management: views from thought

leaders in the field. Hospital Formulary.

34(Sep):776-780, 1999.

Health Services:

• Aparasu R, McCoy RA, Weber C, Mair D,

Parasuraman TV. Opioid-induced emesis

among hospitalized nonsurgical patients:

effect on pain and quality of life. Journal

of Pain & Symptom Management.

18(4):280-288, 1999.

• Cheadle A, Wickizer TM, Franklin G,

Cain K, Joesch J, Kyes K, Madden C,

Murphy L, Plaeger-Brockway R, Weaver

M. Evaluation of the Washington State

Workers' Compensation Managed Care

Pilot Project II: medical and disability

costs. Medical Care. 37(10):982-993,

1999.

• Cook DJ, Giacomini M, Johnson N,

Willms D. Life support in the intensive

care unit: a qualitative investigation of

technological purposes. Canadian

Critical Care Trials Group. CMAJ.

161(9):1109-1113, 1999.

• Corb GJ, Liaw Y, Brandt CA, Shiffman

RN. An object-oriented framework for

the development of computer-based

guideline implementations. Methods of

Information in Medicine. 38(3):148-

153, 1999.

• Forster A, Young J, Langhorne P.

Systematic review of day hospital care

for elderly people. The Day Hospital

Group. BMJ. 318(7187):837-841, 1999.

• Gouveia WA, Shane R. Pharmacy

practice management in the next

century. American Journal of

Health-System Pharmacy.

56(Dec 15):2533, 1999.

• Kyes KB, Wickizer TM, Franklin G, Cain

K, Cheadle A, Madden C, Murphy,

Plaeger-Brockway R, Weaver M.

Evaluation of the Washington State

Workers' Compensation Managed Care

Pilot Project I: medical outcomes and

patient satisfaction. Medical Care.

37(10):972-981, 1999.

• Long MJ, Marshall BS. Case

management and the cost of care in the

last month of life: evidence from one

managed care setting. Health Care

Management Review. 24(4):45-53, 1999.

• Long MJ, Marshall BS. The relationship

between self-assessed health status,

mortality, service use, and cost in a

managed care setting. Health Care

Management Review. 24(4):20-27, 1999.

• Mamdani MM, Racine E, McCreadie S,

Zimmerman C, Stevenson JG. Clinical

and economic effectiveness of an

inpatient anticoagulation service.

Pharmacotherapy. 19(9):1064-1074,

1999.

• Mutnick AH, Szymusiak-Mutnick BA,

Sterba KJ. Drug therapy: evolution of a

documented pharmacist intervention

program. Drug Benefit Trends.

11(Jan):41-45, 1999.

• Naylor MD, Brooten D, Campbell R,

Jacobsen BS, Mezey MD, Pauly MV,

Schwartz JS. Comprehensive discharge

planning and home follow-up of

hospitalized elders: a randomized clinical

trial. JAMA. 281(7):613-620, 1999.

• O'Connor AM, Rostom A, Fiset V, Tetroe

J, Entwistle V, Llewellyn T, Holmes-

Rovner M, Barry M, Jones J. Decision

aids for patients facing health treatment

or screening decisions: systematic review.

BMJ. 319(7212):731-734, 1999.

• Streja DA, Hui RL, Streja E, McCombs

JS. Selective contracting and patient

outcomes: a case study of formulary

restrictions for selective serotonin

reuptake inhibitor antidepressants.

American Journal of Managed Care.

5(9):1133-1142, 1999.

Methodology:

• Berger K, Szucs TD. Socioeconomic

evaluation in medicine in Europe.

Core economic concepts. Pharma-

coeconomics. 16(Suppl 1):19-25, 1999.

• Coyle D, Lee K, Drummond M.

Comparison of alternative sources of

data on health service encounters.

Journal of Health Services & Research

Policy. 4(4):210-214, 1999.

• Weinstein MC. Theoretically correct

cost-effectiveness analysis. Medical

Decision Making. 19(4):381-382, 1999.

• Wyrwich KW, Tierney WM, Wolinsky FD.

Further evidence supporting an SEM-

based criterion for identifying meaningful

intra-individual changes in health-related

quality of life. Journal of Clinical

Epidemiology. 52(9):861-873, 1999.

• Liu G, Zhao Z. Stochastic cost-

effectiveness analysis: a simultaneous

marginal-effect approach. VALUE IN

HEALTH. 2(6):420-8, 1999.

Education:

• Gettman DA, Mann PL. Novel

integration of problem based learning

(PBL) cases into an administrative

pharmacy course. American Association

of Colleges of Pharmacy Annual

Meeting. 100(Jul):70, 1999.

• Pugh CB. Comparison of health-related

quality of life in second year pharmacy

students before and after Christmas

break. American Association of Colleges

of Pharmacy Annual Meeting.

100(Jul):175, 1999. •

13

14

Have you considered submitting a manuscript to VALUE IN HEALTH—the premier peer-

reviewed journal in pharmacoeconomics and outcomes research? VALUE IN HEALTH is actively

soliciting high quality work in pharmacoeconomics and outcomes research, as well as review

articles and guest editorials. Your publication in VALUE IN HEALTH will be seen and used by

researchers and healthcare decision-makers worldwide in this rapidly-growing field.

For more information about VALUE IN HEALTH and manuscript submission instructions, visit

our ISPOR website at www.ispor.org.

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Value in HealthThe Journal of the International Society

for Pharmacoeconomics and Outcomes Research

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ASSOCIATE DIRECTOR / Clinical Development – PharmacoeconomicsTHE COMPANYThe Company, considered one of the worlds most successful biotechnology companies, is a pace setting international company that discovers,develops, and markets biotechnology drugs. The company is dedicated to being the world leader in developing and delivering important, cost-effectivetherapeutics based on advances in cellular and molecular biology.

SCOPE OF THE JOBThe Pharmacoeconomic Program (PE) includes Phase IIIb and Phase IV outcomes research on all of the Company’s products. The Associate Director willguide and coordinate a multidisciplinary team of: healthcare professionals; doctoral trained health services researchers; data analysts; and economist andepidemiologists. There are three major areas of responsibility: 1) developing and managing both internal and external research teams; 2) interacting withscientific thought leaders; 3) participating in program management and strategic planning and design for outcomes research. Research responsibilities willinclude: 1) supporting the development and design of new strategic research initiatives and new research proposals for current and new Company productsthrough identifying, selecting and developing PE research protocols utilizing internal and external clinical data base resources; 2) supervising manuscriptdevelopment for publication and key account presentations based on PE clinical outcomes and comprehensive reviews and analyses of the literature; 3)identifying and creating protocols, proposals, reports and manuscripts for internal and external research resources; 4) supervising and coordinating researchprojects with external database researchers and related manuscript writing and publication; 5) providing review and critique of protocols/manuscripts forinternal staff; 6) close collaborative efforts with marketing and sales managers and national account managers to create and design studies, analyses, andcriteria for evaluating data and database clinical data collection; and 7) assuring quality and timely progress on all programs.

CANDIDATE REQUIREMENTS

We are a retained Executive Health Care search firm. Please respond: Mr. Fred A. Barnette, Fred A. Barnette & Associates, [email protected] or fax 910-256-1183.

1. Doctoral training (MD degree) board certification in internal medicineand licensed in the U.S.

2. Subspecialty in Oncology, Hematology, or Rheumatology is considereda plus.

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5. Clinical and outcomes research experience in a corporate orpharmaceutical industry environment and/or applied research setting.

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This advanced program is for outcomes analysts and economists in thepharmaceutical and medical device industry, and others in academia and government, who conduct or monitor cost-effectiveness analyses

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You will be introduced to the latest methods in the measurement andanalysis of health outcomes data in the context of the most widelyapplied research designs for clinical decision making, health care

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For more information, visit

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phone 617-432-1171

fax 617-432-1969

email [email protected]

CENTER FOR CONTINUING PROFESSIONAL EDUCATION

Where theory informs practice and practice informs theory ®

OR

Code: CEA/MDA0600

School of Public Health

COST-EFFECTIVENESS ANALYSIS FOR MEDICALTECHNOLOGIES AND PHARMACEUTICALS

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16

Career OpportunitySenior Information AnalystHealthcare Economics DepartmentBristol-Myers SuibbPlainsboro, NJ

The Healthcare Economics Group supports the Oncology, MedicalAffairs and U.S. Marketing Divisions through the design andexecution of health economic, outcomes research and financial dataanalyses.This position will analyze the pharmaceutical, hospital, andother clinical and financial databases for the purpose of conductinghealth economic reports and outcomes analyses. In the absence ofof primary clinical and financial databases, the Senior InformationalAnalyst will conduct modeling studies as proxies for true clinicalpractice data. The successful candidate should have a Bachelors orMasters in Public Health, and a strong background inepidemiology, phamacy administration or health economics. Astrong clinical background is essential for this position. Experiencein statistical analysis with a background in clinical research isstrongly recommended. Experience with Microsoft Access, Excel,statistical analysis and decision analysis software is required. Thecandidate should be comfortable working under specified projectdeadlines as well as preparing and delivering oral and writtenreports of study results.

For consideration, please visit www.bms.com/joinus and follow theinstructions on "How To Send A Resume" or mail your resumewith Ad Code PL99-5082 to Human Resources, Bristol-MyersSquibb, P.O. Box 5335, Princeton, NJ 08543-5335. We are anEqual Opportunity Employer.

Outcomes Manager Infomedics, a leader in interactive web and IVR-basedinteractions with patients, is looking for an Outcomes Managerto be responsible for the data and statistical analysis of allmajor Infomedics' programs such as its pharmaceutical basedmarketing support programs.

This position is also responsible for providing report design anddevelopment, supporting sales efforts, serving as the analyticrepresentative in database and data warehouse development,and offering analytic support in product development efforts.Ideal candidate should have bachelor's degree with 3 years ofexperience in analysis and reporting of pharmaceutical or otherhealth care data. The candidate should be skilled in usingstatistical software and experienced in preparing, analyzing, andpresenting health care data to diverse audiences.

Masters degree in Health Care Administration or PublicHealth preferred.

Please submit resume to: Demonda Giokas800 West Cummings Park, Suite 4400Woburn, Ma 01801 Fax number: 781-938-5303, Email: [email protected]

Research Scientist, Quality of Life (Global Pharmaceutical Company): Design, plan and create outcomes research/healtheconomic evaluations with an emphasis on the Quality ofLife components. PhD/MS required. Contact CheriBuonaguidi, Bench International, (310) 854-9900,[email protected]

Research Scientist, Senior Economist (Global Pharmaceutical Company – Midwest): As part of the Global Economic Affairs group, review andsynthesize the epidemiological, clinical, economic andhumanistic literature related to disease prevention andtreatment across the therapeutic areas. Participate in thedevelopment of protocols and analysis plans for Phase II,II, III and IV clinical trials; lead the development ofinnovative studies or methodological applications insupport of commercialization plans. Advanced degree(PhD/MS) required. Expertise in statistics, economics,databases and or decision-analytic modeling and industryor international experience preferred.

Contact Cheri Buonaguidi, Bench International, (310) 854-9900, [email protected]

Director, Health Outcomes ResearchIt's our solid dedication, vision and constant search for answers that allow us totouch millions of people around the world every day. As a major division ofFortune 500 American Home Products Corporation, we help people leadhealthier lives through the development of innovative pharmaceutical, vaccineand nutritional products. We achieve this through our superior research,manufacturing, sales and marketing capabilities. Enjoy the freedom to developyour own career while having the support of a valuable team.

In this position, you will design, implement and supervise research projects in HealthOutcomes & Disease Management, which supports products on a global basis. Youwill identify and direct expert consultants for Medical Affairs and Marketing regardinghealth outcomes and economics support. You will also maintain health outcomesresponsibility for assigned products. Providing support to Sales and Marketing trainingand the training of new health outcomes managers will also be required.

Qualifications include either a degree in a health science, a PharmD or a PhD in aclinically relevant field, and 5 or more years’ experience in health outcomes research,managed care, and/or pharmaceutical R&D. Expertise in Marketing, projectmanagement, health outcomes and database research is also required.

Wyeth-Ayerst offers competitive compensation and benefits programs including stockoptions, child-care subsidies, flex time, business casual Fridays, educational assistanceand professional development programs. Please forward your resume with salaryrequirements to: Wyeth-Ayerst, Reference OIISP, P.O. Box 7886, Philadelphia, PA19101-7886. Fax in fine mode to: (610) 989-4854. Email:[email protected] (ASCII format, no attachments, subject: resume).

Principals only. Equal Opportunity Employer, M/F/D/V.

For more information, visit our website at http://company.monster.com/wyay/

ISPOR 5th Annual International MeetingMay 21-24, 2000 ■ Crystal Gateway Marriott ■ Arlington, VA (Washington, DC area)

Upcoming Events – Mark Your Agenda now!

DATE TIME EVENT OPEN TO

SAT, 20 MAY 9:00 am - 5:00 pm “Write Winning Grants” Seminar, Co-sponsored by All

ISPOR & American Association of Colleges of Pharmacy

SUN, 21 MAY 8:00 am-12:00 pm Board of Directors Meeting 1999-2000 Board of Directors

1:00 - 4:00 pm VALUE IN HEALTH Management Advisory Board ViH Management Advisory Board and Co-editors

2:00 - 5:00 pm Communications Committee Committee Members

5:30 - 8:30 pm Quality of Life Symposium All

Co-sponsored by ISPOR, FDA & PhRMA

MON, 22 MAY 7:30-8:00 am Awards Committee Meeting Committee Members

7:00-8:00 am ISPOR Founders & Leadership Breakfast Invitation only

8:00-10:00 pm Cost-effectiveness in Health & Medicine Panel Dinner Invitation only

TUES, 23 MAY 7:00-8:00 am Institutional Council Breakfast Institutional Council

7:00-8:00 am Faculty Networking Group Breakfast All

7:00-8:00 am VALUE IN HEALTH Editors Breakfast ViH editors

7:00-8:00 am Education Steering Committee Breakfast Committee Members

12:00-1:00 pm Awards Committee Working Lunch Committee Members

5:30-6:30 pm VALUE IN HEALTH Editorial Advisory Board Meeting ViH Editorial Advisory Board

6:30-7:30 pm VALUE IN HEALTH Business Meeting All

5:30-7:30 pm PhRMA Health Outcomes Committee Meeting PhRMA members

5:30-8:00 pm ISPOR Medical Device Technology Forum All

5:30-7:30 pm Student Forum All

7:30-9:00 pm Student Reception All

7:30-9:30 pm VALUE IN HEALTH Reception ViH editors, editorial board,authors and reviewers

8:00-9:00 pm Medical Device Special Interest Group Meeting & Reception All

8:00-9:00 pm Quality of Life Special Interest Group Meeting All

9:00 pm-12:00 am Texas Stomp Party All

WED, 24 MAY 7:00-8:00 am ISPOR Newsletter Committee Breakfast Meeting Committee Members

7:00-8:00 am Statistics Special Interest Group Breakfast All

7:00-8:00 am Managed Care Special Interest Group Breakfast All

7:00-8:00 am Retrospective Analyses Special Interest Grp Breakfast All

7:00-8:00 am Disease Management Special Interest Grp Breakfast All

12:30-2:30 pm 2000-2001 Board of Directors Lunch & Meeting 2000-2001 Board of Directors

12:30-3:00 pm Health Science Steering Committee Lunch & Meeting Committee Members17

SATURDAY, MAY 20 9AM–5PM “WRITE WINNING GRANTS” SEMINAR co-sponsored by ISPORand AACP

SUNDAY, MAY 21 8AM-12PM, 1-5PM TRAINING COURSES — Decision Analysis–Introduction and

Advanced, Quality-of-Life Assessment Fundamentals and Data

Analysis, Measuring Utilities and Willingness-to-Pay, Statistical

Considerations in Pharmacoeconomic Evaluations, Retrospective

Database Analysis, Measuring Productivity

SUNDAY, MAY 21 5:30-8:30PM QUALITY OF LIFE PROMOTIONAL CLAIMS:METHODOLOGICAL ISSUES AND POTENTIAL SOLUTIONS

symposium cosponsored by ISPOR and PhRMA HOC

MONDAY, MAY 22, 2000FIRST PLENARY SESSION: A US Perspective on the Future of

Pharmacoeconomics and Outcomes Research, John M. Eisenberg MD,

MBA, Agency for Healthcare Research & Quality and The Future of

Pharmacoeconomics and Outcomes Research: Will the Bubble Burst?

A European Perspective, Michael Drummond Mcom, Dphil, Centre for

Health Economics, University of York

CONTRIBUTED PODIUM PRESENTATIONS: (4 presentations each)

Decision Analytic Models, Retrospective Database Analyses, Drug &

Health Policy Research, Quality-of-Life Evaluations

ISSUE PANEL DISCUSSIONS: To P or Not to P: Significance Testing

and Confidence Intervals in Outcomes Research, Joseph Heyes PhD,

Merck Research Laboratories, Incorporation of Non-Medical Costs in

Cost-Effectiveness Analysis: A Practical Guide, Bernard Bloom PhD,

University of Pennsylvania, Is There Utility to Utilities? Bernie O’Brien

MD, McMaster University, The Role of Consumers in Medical Decision

Making, Myrl Weinberg, National Health Council

EXHIBITS and CONTRIBUTED POSTER PRESENTATIONS:Cardiovascular Disease Research (26)*, Mental Health, Migraine, Pain

& Neurological Disorders Research (42), Osteoporosis Research (5),

Arthritis Research (7), Women’s and Men’s Health Disorders Research

(6), Economic & Outcomes Research Methodological Issues (37),

Willingness-to-Pay and Work Performance Research (6)

CONTRIBUTED WORKSHOPS (15)*EXHIBITORS OPEN HOUSE AND RECEPTION

TUESDAY, MAY 23, 2000SECOND PLENARY SESSION: The 21st Century: Are We Finally

Ready for Health Care Quality? William L. Roper MD, MPH, School of

Public Health, University of North Carolina at Chapel Hill and Is There

Life After Capitation? The US Health Care System After the Managed

Care Revolution JD Kleinke MSB, Health Strategies Network

CONTRIBUTED PODIUM PRESENTATIONS: (4 presentations each)

Productivity / Indirect Costs, Cost-Analyses, Cost-Effectiveness /

Cost-Benefit Analyses (Session 1), Drug Utilization / Compliance

ISSUE PANEL DISCUSSIONS: Use and Abuse of Administrative Data:

Selection Bias in Retrospective Research, J. Michael Sprafka MPH, PhD,

Proctor & Gamble, Extrapolating from Efficacy to Effectiveness: Issues

and Controversies, Clifford Goodman PhD, The Lewin Group, Cost-

Effectiveness vs. Budgetary Impact: Breaking Down the Silos, Scott

Weingarte MD, MPh, Zynx Health Inc., Evolving Issues in Prescription

Drug Coverage, Patricia Deverka MD, MS, Merck-Medco Managed Care

EXHIBITS and CONTRIBUTED POSTER PRESENTATIONS:Infectious Diseases and HIV Research (31)*, Cancer Research (17),

Diabetes Research (11), Renal / Urinary Disorders Research (9),

Respiratory Disorders Research (10), Surgical Procedures & Hospital

Resource Use Research (14), Gastrointestinal Disorders Research (4),

Drug Use & Drug / Healthcare Policy Research (33)

CONTRIBUTED WORKSHOPS (15)*

ISPOR MEDICAL DEVICE TECHNOLOGY FORUM: organized by

the ISPOR Medical Device Technology Council, Introductions and

Medical Device Technology Forum Objectives, Eileen Helzner MD,

Johnson & Johnson, Overview of Medical Device Technology, Annetine

Gelijns PhD, Columbia University, Unique Challenge for Medical

Device Outcomes Research, Stacey Ackerman PhD, Covance Inc,

Addressing the Specific Needs of Medical Device Outcomes Research,

Donald Chalfin MD, MS, Beth Israel, New York

ISPOR STUDENT FORUM Introduction, Mohamed Omar RPh,

University of Texas, Welcome, Bryan Luce PhD, MBA, MEDTAP

International, ISPOR Student Awards, Kent Summers RPh, PhD,

Eli Lilly and Company, ISPOR Student Chapter Reports, How To Give

Winning Presentations, Jean Paul Gagnon PhD, Aventis Pharmaceuticals

Inc., Health Outcomes Research in the Pharmaceutical Industry,

Zeba Khan MS, PhD, Glaxo Wellcome Inc.

RECEPTIONS: Student, Medical Device Technology, Quality-of-Life

Special Interest Group, VALUE IN HEALTH

TEXAS STOMP PARTY

WEDNESDAY, MAY 24, 2000CONTRIBUTED PODIUM SESSIONS: (4 each)* Methodologic Issues

/Advances, Student Session, Burden of Illness / Trial-Based Economic

Evaluations, Cost-Effectiveness / Cost-Benefit Analyses (Session 2)

THIRD PLENARY SESSION: Pharmaceutical Regulation: The Early

Experience of the NHS National Institute for Clinical Excellence—

Where Are We Headed? Rod Taylor BSc(Hons), MSc, PhD, National

Institute for Clinical Excellence (NICE) US Regulation of the

Pharmaceutical Industry: Can the Past Predict the Future? Laurie Beth

Burke RPH, MPH, Regulatory Review Branch, FDA, CDER, DDMAC,

Regulation and Promotion of Outcomes Research Now and in the

Future: An Industry Perspective, Paul Radensky MD, JD, Health Law

Department, McDermott, Will & Emory

ISPOR 5th Annual International MeetingMay 21-24, 2000 ■ Crystal Gateway Marriott ■ Arlington, VA (Washington, DC area)

SUMMARY OF EVENTS

* number of presentations

MEETING REGISTRATION FORMNAME DEGREES

POSITION ORGANIZATION

MAILING ADDRESS

CITY STATE ZIP COUNTRY

TELEPHONE FAX EMAIL

ISPOR Member Non-Member*

CONFERENCE REGISTRATIONRegistration Before May 1, 2000 ■■ US$ 600 ■■ US$ 735Registration After May 1, 2000 ■■ US$ 700 ■■ US$ 835

Clinical Practitioners (PBM, HMO, Hospital)

Registration Before May 1, 2000 ■■ US$ 450 ■■ US$ 585Registration After May 1, 2000 ■■ US$ 550 ■■ US$ 685

Full-Time Government and AcademiaRegistration Before May 1, 2000 ■■ US$ 300 ■■ US$ 435Registration After May 1, 2000 ■■ US$ 400 ■■ US$ 535

Full-Time Students (must provide current enrollment documentation)

Registration Before May 1, 2000 ■■ US$ 75 ■■ US$ 125Registration After May 1, 2000 ■■ US$ 100 ■■ US$ 150

One Day Registration ■■ US$ 250 ■■ US$ 250

Accreditation ■■ US$ 30 ■■ US$ 30

REGISTRATION FEE: $_________ $ _________

TOTAL REGISTRATION FEE WITH SHORT COURSES AND SEMINAR: $_________ $ _________

PRE-MEETING GRANT WRITING SEMINARSaturday, May 20, 9:00am - 5:00pm (check appropriate box)■■ AACP member $125 ■■ Non-member AACP $150

PRE-MEETING TRAINING COURSE REGISTRATION / Each course 4 hrs

(Check one course from the AM session and/or one course from the PM session)

MORNING SESSIONS Sunday, May 21, 8:00am – 12:00pm

■■ Decision Analysis – Introduction

■■ Quality-of-Life Assessment Fundamentals

■■ Measuring Utilities and Willingness-to-Pay

■■ Statistical Considerations in Pharmacoeconomic Evaluations

AFTERNOON SESSIONS Sunday, May 21, 1:00pm – 5:00pm

■■ Decision Analysis – Advanced ■■ Quality-of-Life Data Analysis

■■ Retrospective Database Analysis ■■ Measuring Productivity

Registration Fee Before May 1, 2000 ■■ US$ 125 [ x no. of courses= ]

Registration Fee After May 1, 2000 ■■ US$ 175 [ x no. of courses= ]

Student Fee Before May 1, 2000 ■■ US$ 50 [ x no. of courses= ]

Student Fee After May 1, 2000 ■■ US$ 75 [ x no. of courses= ]

Total: ___________

PRE-MEETING QUALITY OF LIFE SYMPOSIUM (no fee)Sunday, May 21, 5:30-8:30 PM (check box if participating)■■ Quality of Life Promotional Claims: Methodological Issues and

Practical Solutions

Please enclose a check payable in US dollars to: International Society for Pharmacoeconomics and Outcomes Research or ISPOR and send to the ISPOR address given below or charge to: ■■ VISA ■■ MasterCard ■■ American Express

NAME: AUTHORIZED SIGNATURE:

ACCOUNT NUMBER: EXPIRATION DATE:

Payment must be made in US dollars. Payment may be made by check or travelers check. VISA, MasterCard, or American Express will be charged in US dollars.Signature, account number, and expiration date must be included. Non-US checks written in US$ must be written on banks with a US counterpart. Phone chargeswill NOT be accepted. If payment is being made by your company, please make sure your name is indicated on the check stub or correspondence. *When you register as a non-member, you receive ISPOR membership until December 31, 2000 and a one-year subscription to VALUE IN HEALTH-The Journal of theInternational Society for Pharmacoeconomics and Outcomes Research.

Cancellation fee before May 1, 2000 is US $100. No refunds given after May 1, 2000.

SEND REGISTRATION FORM (OR FAX, IF USING CREDIT CARD) TO:International Society for Pharmacoeconomics and Outcomes Research

20 Nassau Street, Suite 307, Princeton, NJ 08542 USA Tel: 1-609-252-1305 Fax: 1-609-252-1306 Email: [email protected] Internet: www.ispor.org

ISPOR 5th Annual International MeetingMay 21-24, 2000 ■ Crystal Gateway Marriott ■ Arlington, VA (Washington, DC area)

International Society for Pharmacoeconomics and Outcomes Research20 Nassau Street, Suite 307 Princeton, NJ 08542 USA

Nonprofit Org

US Postage

PAIDPrinceton NJ

Permit 783

ISPOR Newsletter is published bimonthly by ISPOR20 Nassau Street, Suite 307, Princeton, NJ 08542 USA Phone: 609-252-1305 Fax: 609-252-1306

ISPOR Newsletter Committee: Anita Burrell, Mireille Goetghebeur, Bonnie Korenblat, Steve E. Marx, Richard J. Milne, Helma Monteban, Mohamed Omar, Donna Rindress, Malcolm Weiss, Sharon Welner, Peter K. Wong, Albert Wertheimer

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You will find something better at Smith Hanley

Pharmaceutical Permanent & ContractOpportunities for

Outcomes ResearchPharmacoeconomicsEpidemiologyBiostatisticsSAS® ProgrammingData ManagementClinical Information Systems

Smith Hanley offers a diversity of placementopportunities for recent graduates to senior professionals in pharmacoeconomics, outcomesresearch and epidemiology.

Choose from a wide variety of permanent employment opportunities at prestigious companies, or join Smith Hanley Consulting and work onassignments at the same companies.

You will find something better at Smith Hanley.

Contact: Kevin McGrath800.989.5627 • Fax: 212.818.9067E-mail: [email protected]

99 Park Avenue, 9th FloorNew York, NY 10016

www.smithhanley.com


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