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The University of Western AustraliaSchool of Psychiatry and Clinical Neurosciences

Neuropsychiatric Epidemiology Research Unit (NERU)Annual Report 2013 1995-2012 Historical appendices

Neuropsychiatric Epidemiology Research Unit ANNUAL REPORT 2009-2011

Neuropsychiatric Epidemiology Research Unit ANNUAL REPORT 20132

Cover photo: Johannes Knutsson

NERU.A mountain in Himavā. All birds settling there become golden


CONTENTS

CONTENTS 3

STRUCTURE 2013 4

RESEARCH PROGRAMS 5

METHODOLOGIES and APPROACHES 16

INSTRUMENT DEVELOPMENT 18

STAFF 2013 20

RESEARCH FUNDING RECEIVED/COMMITTED 2012 ONWARDS ($) 21

PUBLICATIONS 2013 23

ORAL CONFERENCE PRESENTATIONS 2013 25

POSTER PRESENTATIONS 2013 26

OTHER TALKS AND PRESENTATIONS 2013 27

POSTGRADUATE STUDENTS 2013 28

RESEARCH COLLABORATIONS AND ACTIVITIES 2013 29

STAFF: AWARDS AND PRIZES 2013 32

STAFF: FORMAL OFFICES HELD 2013 32

STAFF: CONFERENCE ORGANISING COMMITTEES 2013 32

STAFF: EDITORIAL COMMITTEES 2013 32

STAFF: OTHER COMMITTEE MEMBERSHIP 2013 33

STAFF: CURRENT PROFILE 34

NERU Location and contact details 40

APPENDIX 1a. Research Funding 2004-2011 ($) 41

APPENDIX 1b. Research Funding 1995-2003 ($) 43

APPENDIX 2. SELECTED PUBLICATIONS 1995-2012 (Epidemiology) 44


STRUCTURE 2013

Neuropsychiatric Epidemiology Research Unit

Figure 1.Organisational structure, Neuropsychiatric Epidemiology Research Unit, 2013


RESEARCH PROGRAMS

Pathways of risk from conception to disease: a population-based study of theoffspring of women with schizophrenia, bipolar disorder and other psychotic disorders

V Morgan, G Valuri, M Croft, J Griffith, S Shah, P Di Prinzio, K Brameld, Taryn Major, D Young, S Zubrick, C Bower, T McNeil, F Morgan, K Abel, A Jablensky

Our aim in this study is to integrate genetic and risk factor epidemiology under a developmental perspective in order to examine reproductive pathology in women with severe mental illness and follow-up proximal and distal developmental and neuropsychiatric sequelae in their children. Children at increased familial risk for severe mental illness are compared with children at no increased familial risk on a wide range of developmental indices and environmental risk factors, including obstetric events, with a view to elucidating the intergenerational transmission of both vulnerability and resilience to adverse neuropsychiatric outcomes. These outcomes include, among others, birth defects, intellectual disability, pervasive developmental disorders, epilepsy, psychiatric illness and psychosis.

This is a whole-of-population record linkage study, using linkage across psychiatric, physical morbidity, mortality and other administrative registers in Western Australia to follow up a large whole-of-population cohort of 467,945 children born between 1980 and 2001 to 246,874 mothers. This includes 15,486 births to 7508 mothers with a psychotic illness.

In the course of this study, we have developed and refined a number of instruments, including the Diagnostic Interview for Psychoses (casenotes version) and the Children’s Checklist, extended the McNeil-Sjöström Scale for Obstetric Complications; and developed measures of neonatal encephalopathy and of maternal morbidity over time. We are also developing measures of adversity across individual, familial and ecological settings using our record linked data. Using quantitative and qualitative data, we are constructing developmental life course histories for a subsample of the children in our study.

Currently, we are examining the following outcomes; maternal reproductive morbidity and early neonatal morbidity; stillbirths, perinatal and childhood mortality sudden infant death syndrome; early neuropsychiatric outcomes including birth defects, intellectual disability

and rare syndromes; education outcomes; childhood victimisation (using prospectively collected child protection data);

and criminal offending, including offending trajectories.

In work in progress, the children’s mental health outcomes are being reviewed. We are working towards our flagship paper that will examine familial and environmental risks for psychosis in these high risk children of mothers with psychosis.

http://www.ncbi.nlm.nih.gov/pubmed/20870781



Pregnancy, Delivery, and Neonatal Complications in a Population Cohort of Women with Schizophrenia and Major Affective Disorders

A Jablensky, V Morgan, S Zubrick, C Bower, L-A Yellachich

The Pathways of Risk project builds on an earlier study of the same design but utilising a smaller cohort of 6303 children born 1980-1992. This was also a population-based study with record linkage across several morbidity case registers and databases in Western Australia. The aims of the study were to determine the frequency, nature, and severity of obstetric complications experienced by women with schizophrenia compared to women with affective disorders and women without a diagnosed psychiatric disorder, to investigate the temporal relationship between pregnancies and the onset of maternal psychiatric illness, and to explore a range of pregnancy outcomes in relation to maternal risk factors.

The study found the mothers with both schizophrenia and affective disorder had increased risks of pregnancy, birth, and neonatal complications, including placental abnormalities, antepartum hemorrhages, and fetal distress. Women with schizophrenia were significantly more likely to have placental abruption, to give birth to infants in the lowest weight/growth population decile, and to have children with cardiovascular congenital anomalies. Neonatal complications were significantly more likely to occur in winter; low birth weight peaked in spring. Complications other than low birth weight and congenital anomalies were higher in pregnancies after psychiatric illness than in pregnancies preceding the diagnosis.

Table. Figure.Significant findings: Obstetric complications Obstetric complications in women with (OR, 95% CI) schizophrenia relative to onset of

psychiatric illness (%)

While genetic liability and gene-environment interactions may account for some outcomes, maternal risk factors and biological and behavioral concomitants of severe mental illness appear to be major determinants of increases in reproductive pathology in this cohort. Risk reduction in these vulnerable groups may be achievable through antenatal and postnatal interventions.

http://www.ncbi.nlm.nih.gov/pubmed/22241931http://www.ncbi.nlm.nih.gov/pubmed/15625205


66.1

30.5

43.3

32.6

70.1

34.8

50.1

39.5

0

20

40

60

80

100

Any obstetriccomplication

Pregnancycomplication

Labour and deliverycomplication

Neonatalcomplication

Composite scale scores

Birth before onset of schizophrenia Birth after onset of schizophrenia

%

8



Intellectual disability comorbid with schizophrenia and other psychotic disorders

Study 1: Intellectual disability and other neuropsychiatric outcomes in high-risk children of mothers with schizophrenia, bipolar disorder and unipolar major depression

V Morgan, M Croft, G Valuri, S Zubrick, C Bower, T McNeil, A Jablensky

This study used the data collected as part of the study of Pregnancy, Delivery, and Neonatal Complications in a Population Cohort of Women with Schizophrenia and Major Affective Disorders.

The aims of this study were: (a) to determine the risk of intellectual disability, rare syndromes, pervasive developmental disorders, convulsions and epilepsy in a population-based cohort of children of women with schizophrenia compared with children of women with no recorded psychiatric history; (b) to examine the role of obstetric complications in mediating the risk of intellectual disability; and (c) to assess the specificity of findings to maternal schizophrenia compared with maternal bipolar disorder and unipolar major depression.

Our findings provide epidemiological support for clustering of neuropsychiatric disorders in children of women with psychotic illness. Children were at significantly increased risk of intellectual disability with odds ratios (ORs) of 3.2 (95% CI 1.8–5.7), 3.1 (95% CI 1.9–4.9) and 2.9 (95% CI 1.8–4.7) in the maternal schizophrenia, bipolar disorder and unipolar depression groups respectively. Multivariate analysis suggests familial and obstetric factors may contribute independently to the risk. Although summated labour/delivery complications (OR = 1.4, 95% CI 1.0–2.0) just failed to reach significance, neonatal encephalopathy (OR = 7.7, 95% CI 3.0–20.2) and fetal distress (OR = 1.8, 95% CI 1.1–2.7) were independent significant predictors. Rates of rare syndromes in children of mothers with mental disorder were well above population rates. Risk of pervasive developmental disorders, including autism, was significantly elevated for children of mothers with bipolar disorder. Risk of epilepsy was doubled for children of mothers with unipolar depression.


Table. Intellectual disability; pervasive developmental disorders, rare syndromes, convulsions and epilepsy in children, by maternal psychiatric status (N=6303)

Unadjusted Odds Ratios

Schizophrenia v.comparison offspring

Bipolar v.comparison offspring

Unipolar v.comparison offspring

Odds Ratio 95% CI Odds Ratio 95% CI Odds Ratio 95% CIIntellectual disability 3.2 1.8 - 5.7* 3.1 1.9 - 4.9* 2.9 1.8 - 4.7*Any rare syndrome† 8.5 2.0 - 35.7* 4.0 1.0 - 16.8 2.5 0.5 - 12.4Pervasive develop-mental disorders ‡ 5.1 0.3 - 81.2 9.6 1.1 - 86.4* 7.5 0.8 - 72.1

Convulsions 1.4 0.9 - 2.1 1.3 1.0 - 1.9 1.4 1.0 - 2.0*Epilepsy 0.7 0.2 - 2.3 1.8 0.9 - 3.4 2.3 1.2 - 4.2** Confidence interval does not straddle 1. Does not include confidence intervals where the lower limit has been rounded up to 1.† Includes Hurler, Klinefelter, Moebius, Noonan, Prader-Willi, Rett, Rubinstein-Taybi, VATER Association and Turner ‡Pervasive developmental disorders (including autism) with co-occurring intellectual disability



Study 2: Intellectual disability co-occurring with schizophrenia and other psychiatric illness: population-based study

V Morgan, H Leonard, J Bourke, A Jablensky

The epidemiology of intellectual disability co-occurring with schizophrenia and other psychiatric illness is poorly understood. The separation of mental health from intellectual disability services has led to a serious underestimation of the prevalence of dual diagnosis, with clinicians ill-equipped to treat affected individuals. The aim of this study was to use record linkage across population-based psychiatric and intellectual disability registers in order to estimate the prevalence of dual diagnosis and describe its clinical profile.

This study highlights the extent to which dual diagnosis is underestimated as a result of the administrative divide that has existed historically between services for people who are intellectually disabled and those for people with psychiatric illness. We found that, overall, 31.7% of people with an intellectual disability had a psychiatric disorder; 1.8% of people with a psychiatric illness had an intellectual disability. Had the study relied on single register data, the figures would have been much lower, seriously underestimating the size of the problem of dual diagnosis in the population.

Our results are suggestive of a common pathogenesis in intellectual disability co-occurring with schizophrenia. Total psychiatric morbidity in intellectually disabled populations is comparable with general population estimates of lifetime prevalence of 41.2%. However, schizophrenia, but not bipolar disorder and unipolar depression, was greatly overrepresented among individuals with a dual diagnosis: depending on birth cohort, 3.7–5.2% of those with intellectual disability had co-occurring schizophrenia (4.4% across both cohorts). This is at least three times higher than population lifetime estimates (most recently 1.26%), but also higher than the commonly quoted estimate of 3% for schizophrenia among intellectually disabled populations.

Individuals with a dual diagnosis, compared to those with intellectual disability only appeared to have a different presumed aetiology: they were significantly less likely to have a genetic or other known biomedical basis to their disorder, significantly less likely to have Down syndrome, and significantly more likely to have pervasive developmental disorder. Individuals with a dual diagnosis, compared to those with psychiatric illness only, had a more severe psychiatric illness, and earlier age at first contact with mental health services, more inpatient admissions, more inpatient days, and a higher mortality rates.

http://www.ncbi.nlm.nih.gov/pubmed/ 18978313

Table. Dual diagnosis as a percentage of total number of persons with (i) specified psychiatric illness (PI) and (ii) any intellectual disability (ID)

Dual diagnosis

(N)

SpecifiedPI(N)

Dual diagnosisas % of specified PI

Dual diagnosiswith specified PIas % of all ID

(N=13,295)Schizophrenia 485 11,520 4.2 3.6Bipolar disorder 112 8556 1.3 0.8Unipolar depression 95 15,000 0.6 0.7Psychosis (lifetime) 1115 60,206 1.9 8.4Any psychiatric illness 4221 236,675 1.8 31.7



Other environmental risk factors for schizophrenia: Influenza and season of birth

Study 1: Influenza epidemics and incidence of schizophrenia, affective disorders and mental retardation in Western Australia: No evidence of a major effect

V Morgan, D Castle, A Page, S Fazio, L Gurrin, P Burton, P Montgomery, A JablenskyIn utero exposure to influenza has been implicated as a risk factor for developmental CNS damage. This ecological study tested the hypothesis that in utero exposure to influenza: (1) in the second gestational trimester is associated with an increased risk of schizophrenia and affective psychoses; (2) in the first gestational trimester is associated with an increased risk of mental retardation.

The data were examined for effects associated with six influenza epidemics in the period 1950-1960. Using relative risk ratios for individual epidemics as well as Poisson regression and a proportional hazards model to examine systematic effects for the whole period, no major effect could be identified for maternal influenza on the incidence of schizophrenia, affective psychoses and neurotic depression, despite sufficient statistical power to detect an effect. However, a possible effect was found for mental retardation in males exposed in the first and second gestational trimester.

www.ncbi.nlm.nih.gov/pubmed/9376335

See also: Schizophrenia and 1957 Pandemic of Influenza: Meta-analysis

J-P Selten, A Frissen, G Lensvelt-Mulders, and V Morgan

This is a more recent meta-analysis that included the original data. It did not support the hypothesis of maternal influenza as a risk factor for schizophrenia.


Study 2: Season of birth in schizophrenia and affective psychoses in Western Australia1916-61

V Morgan, A Jablensky, D Castle

This study examined seasonality birth effects in schizophrenia and affective psychoses in the southern hemisphere, given possible confounding of age-incidence effects with winter birth peaks in northern hemisphere data.

We found no association between season of birth and schizophrenia, affective psychoses or neurotic depression. For schizophrenia, the pattern of risks by quarter reflects northern hemisphere trends, with the risk was increased in the third quarter (covering late winter, early spring) for females only (RR 1.15, CI 1.01-1.32) and decreased in the fourth quarter for females (RR 0.81, CI 0.70-0.94), and for males and females combined (RR 0.87, CI 0.79-0.96). These results are in the direction of trends in northern hemisphere data. However, using a more stringent epidemiological criterion of a relative risk of 2 or more (or 0.5 or less) with the confidence interval not straddling unity, the magnitude of the calculated relative risks would not be regarded as substantial.




While age-incidence effects had no impact on the distribution of risk, we found an artefactual increase in January births due to routine imputation of missing birth dates. Adjusting for artefacts in the data produced a pattern analogous to northern hemisphere trends.

www.ncbi.nlm.nih.gov/pubmed/11473508



The Australian perinatal mental health reforms: using population data to evaluate their impact on service utilisation and related cost-effectiveness

M-P Austin, E Sullivan, N Highet, V Morgan, C Mihalopoulos, M Croft, K Brameld in partnership with beyondblue.

Mental health problems associated with the perinatal period – defined as from conception to the end of the first postnatal year – are recognised as a major public health issue with significant morbidity and costs for mother, infant, and family. Left untreated they may impact on the health of the next generation. The last decade has seen a burgeoning of perinatal mental health initiatives in Australia, including the National Perinatal Depression Initiative (NPDI), yet there is currently a gap in our understanding of how these initiatives have met their goal of improving maternal mental health outcomes through improved uptake of services, at this critical time. This project is using population health data to examine the impact of the reforms on maternal health outcomes, service utilisation and the likely cost-effectiveness of these reforms.

This project employs four key methodologies: i) data linkage; ii) generation of perinatal-specific Medicare Benefits Schedule summary data; iii) economic and policy analyses; and, iv) key stakeholder consultations in a consideration of the further implementation and evaluation of the Depression Initiative NPDI.

The findings from this project will facilitate improvements in the recognition, prevention, and treatment of mental health morbidity among perinatal women. It will provide information for the provision of effective mental health services to this vulnerable – and eminently accessible – population. This project will empower beyondBlue, as its Partner Organisation, to use the findings to strengthen collaborations, advocate for a cohesive approach to the future implementation of the NPDI, and influence policy and decision making at jurisdictional and national levels. From an international perspective, this project will put Australia at the forefront of policy planning, analysis and cost-effectiveness evaluation in the field of perinatal mental health.


Survey of High Impact Psychosis WAve 2 (SHIP WAve 2)

V Morgan, A Jablensky, Gerald Watts, Johanna Badcock, Kay Cox, Nikos Stefanis, A Waterreus, J Griffith, Patsy Di Prinzio, Sonal Shah

People with severe mental illness have high rates of cardiometabolic disease and reduced life-expectancy compared to the general population. Our primary objective is to improve physical health in people with severe mental illness who are already burdened by the severe symptoms of their mental illness and the multiple side effects of psychotropic medication used to treat those symptoms. Unfortunately, public intervention campaigns have had little impact on component risks for cardiometabolic disease (for example, obesity, smoking, substance abuse, low levels of physical activity and poor nutrition) in people with severe mental illness. We argue that targeted interventions embedded within mental health service delivery are essential. To be effective, these interventions must (i) take into account factors associated with severe mental illness including the side-effect profile of psychotropic medication use, cognitive biases and psychopathology, and (ii) be informed by specific person- and system-related impediments to risk modification in this group.

AimsThis NHMRC-funded study builds on a rare opportunity to collect longitudinal data on a population-based sample of people with psychotic illness, first assessed comprehensively between 2010 and 2013. Its objective is to fill the knowledge gap on cardiometabolic disease risk modification in people with psychotic illness. To achieve this, its aims are to:1. Determine factors associated with improvement and deterioration in

cardiometabolic profiles in people with psychotic illness;2. Examine impediments to the uptake of interventions for cardiometabolic

disorders by people with psychotic illness; and3. Work with services towards the development of a clinical service model for the

implementation of targeted interventions within mental health services.

OverviewThe study will follow up, from 2013 to 2016, over 600 Western Australians with psychosis, thoroughly assessed in south metropolitan Perth as part of the 2010 National Survey of High Impact Psychosis (South Metro SHIP) and in 2012 in north metropolitan Perth in a SHIP expansion survey (North Metro SHIP). Almost all participants (98%) have agreed to being recontacted for participation in a follow up interview. By staggering the interviews, follow up time will be 3-5 years.

Follow up will include a face-to-face interview during which the interviewer will collect data on: lifestyle risk factor profiles and cardiometabolic outcomes including change

over time; other known predictors of cardiometabolic outcomes including medication use

and family history; individual level impediments to the uptake of risk modification measures and

potential correlates of cardiovascular risk (e.g. cognitive functioning; loneliness; motivation; work and other community participation; health literacy);

mental health service level factors that may impede/facilitate effective physical health monitoring and management (e.g. case management, rehabilitation programs, personal helper programs, access to primary care);

potential correlates of improved health including independent functioning, satisfaction and quality of life; and

symptomatology.


There will also be a physical health assessment including fasting blood tests and the taking of measures for blood pressure, pulse, waist circumference, height and weight.

We will augment interview data with electronic data from population health registers. This includes linking to Commonwealth pharmaceutical benefits scheme and medical benefits scheme data for a detailed, longitudinal history of pharmaceutical prescriptions and of general practice and specialist service use, as well as data held on Western Australian health registers.

We will ask participants' general practitioners to complete a questionnaire about the participant on: physical health treatment, tests and referrals; barriers to treatment take-up; and stigma/discrimination in the general practice setting.

The Wave 2 follow up will allow us to distinguish prevalent cases of metabolic syndrome first assessed at Wave 1 from new incident cases identified at Wave 2, and to examine the association between changes in risk factor profiles and cardiometabolic outcomes separately for these two groups.

This observational study will provide unique information from an unbiased cohort followed up over two time points. The natural experimental design offers advantages over a clinical trial by capturing the range of people with psychosis and assessing behaviour in real world individual and service contexts. As such, this study has a very high utility value for mental health service planning.

The 2010 Australian National Survey of High Impact Psychosis (SHIP)

V Morgan, A Jablensky, A Waterreus, J Griffith, Patsy Di Prinzio, Sonal Shah

The aims of this survey were (i) to describe the prevalence and profile of psychosis in Australia and (ii) to identify factors associated with good outcome in psychosis that are amenable to change and critical to recovery with the intention of informing policy development and service planning. The survey is an initiative of psychosis researchers and clinicians across Australia in partnership with the Australia Government Department of Health and Ageing. It is a follow-up to the first Australian National Survey of Low Prevalence (Psychotic) Disorders, conducted in 1997-98 by Prof Assen Jablensky. It has collected national data that provided an evidence base for understanding barriers to good outcomes for people with psychosis, including their social and economic integration.

SHIP asks questions about: symptoms, utilisation of mental health and other services; perceived need; education; cognition; social participation (work and skill development; activities of daily living; family responsibilities; other social engagement and community integration); living circumstances; support networks; physical well-being (including a physical health assessment; physical activity; nutrition; risk factors for metabolic syndrome and cardiovascular disease; smoking); and drug and alcohol use.

SHIP took place at seven sites in five states across Australia: NSW, QLD, SA, VIC and WA. It used a two-phase sampling design. Phase 1 screening for psychosis took place in the census month which was March 2010. In Phase 2, 2000 individuals aged 18-64 were randomly selected for participation, from those screen-positive for psychosis, to be interviewed and assessed. The interview phase was completed at the end of 2010. The report to the Australian Government Department of Health and Ageing was completed in 2011 and the first series of papers, including an overview paper, was published in 2012.


Papers from this study are available for downloading at:http://www.psychiatry.uwa.edu.au/research/neru/survey/researchers


North Metro Survey of High Impact Psychosis (North Metro SHIP)

V Morgan, A Waterreus, J Griffith, A Jablensky, Patsy Di Prinzio, Sonal Shah

This extension of the national SHIP survey, in North Metropolitan Area Health Services Mental Health, was funded by the Mental Health Commission and the Western Australian Department of Health. The survey census month was March 2012 with interviews taking place from April 2012 to April 2013. The aims were to: estimate the local prevalence of psychosis in North Metropolitan Area Health

Service; describe the social and economic circumstances of people living with

psychosis within North Metro, as well as their mental and physical health profiles and their use of services;

develop a local evidence base to help inform mental health policy development and service providers in North Metro,

develop services to meet specific local needs to benefit people living with psychosis, their friends, family, carers and services supporting them.

The 1997-98 Study of Low Prevalence (Psychotic) Disorders

A Jablensky, V Morgan, A Waterreus, J Griffith,

This survey, Australia's first national survey of psychosis, followed several years of discussion and consultation before a major decision was made in late 1994 by the Australian Health Ministers’ Advisory Council to proceed. The rational planning of mental health services, in accordance with the adopted National Strategy, required an epidemiological database, and such information could only be provided by a nationally representative survey. A core group of individuals, including Harvey Whiteford, Gavin Andrews, Scott Henderson and Wayne Hall, formulated the broad parameters of a survey that would encompass three interrelated, yet relatively independent studies: a representative national sample of the adult population, a catchment-area based investigation of psychotic (“low prevalence”) disorders, and a school-based sample of children and adolescents.

Assen Jablensky was invited to submit proposals for the design of the low-prevalence arm of this national endeavour to the Steering Committee, chaired by Scott Henderson. It was to be a major undertaking. Intense Discussions with Helen Herrman, John McGrath, Scott Henderson and other researchers helped towards agreement on a plan that envisaged selection of geographical catchment areas in the Australian Capital Territory, Queensland, Victoria and Western Australia for a two-phase survey involving a census and screening of all contacts with the mental services and a selected number of general and private practices, to be followed by interviewing of a sample of people with psychotic illnesses. The team at The University of Western Australia, including Assen Jablensky, David Castle, Vera Morgan and Anna Wattereus, was entrusted with the coordination of the multi-centre research network and worked with interstate colleagues and field interviewers, including NERU's Jenny Griffith, over the next two years to get the survey ready.

The results of the Low Prevalence (Psychotic) Disorders Study were published in a major report and a number of journal articles. Apart from generating point prevalence data for psychotic disorders in urban areas in Australia for the first time, the study was unique in ascertaining symptom profiles, rates of functional impairments and disability, indices of quality of life, substance use co-morbidity, service utilisation patterns, and side effects of medication. Subsequent economic analyses coordinated by Vaughan Carr provided estimates of direct and indirect costs associated with psychotic disorders. One of the “best selling” products of


the study was the research instrument, the Diagnostic Interview for Psychosis (DIP), which was designed by the Western Australian group.


Key papers and reports from this study are available for downloading at:http://www.psychiatry.uwa.edu.au/research/neru/survey/researchers/the-1997-98-study-of-low-prevalence-psychotic-disorders

Schizophrenia and criminal offending

Study 1: A whole-of-population study of the prevalence and patterns of criminal offending in schizophrenia and other psychiatric disorders

V Morgan, F Morgan, G Valuri, A Ferrante, D Castle, A Jablensky

This study employed a methodologically sound, population-based research design to provide reliable data on the association between offending and serious mental illness. Its aims were: to (i) estimate the prevalence of offending in people with a mental illness compared to the general population; (ii) to describe patterns of offending in people with a mental illness compared to the general population; and (iii) to compare findings for people with schizophrenia with those with other mental illness.

The vast majority (89%) of offenders arrested between 1986 and 1996 did not have a mental illness. Eighty percent of those arrested for a violent offence did not have a mental illness, 6% had a substance abuse disorder, 2% had a personality disorder and 2% had schizophrenia. Seventy percent of those arrested for homicide in the same period did not have a mental illness, 9% had a substance abuse disorder, 3% had a personality disorder and 3% had schizophrenia.

Among people with a mental illness, the prevalence of offending over a 12 year period from 1986-1996 was 32% overall. The prevalence was differentially distributed, depending on diagnosis, and was highest for substance abuse disorders (59%). The prevalence for schizophrenia was 39%.

A comorbid substance abuse disorder significantly increased the risk of a violent offence for people with schizophrenia.

For the majority of offenders with a mental illness, their first arrest preceded their first contact with mental health services. This proportion had increased to 66% over time for people with schizophrenia.

The annual change in the number of arrests over a 12 year period from 1986-1996 for the cohort born 1955-1969 decreased significantly for people with no mental illness and increased significantly for those with a mental illness other than schizophrenia. There was no overall change for people with schizophrenia but there was a peak in the pattern of arrests in 1991-1993, coinciding with a period when community mental health services were poorly resourced to meet demands created by deinstitutionalisation of patients from psychiatric institutions.


Study 2: Schizophrenia and offending: area of residence and the impact of social disorganisation and urbanicity

F Morgan, V Morgan, J Clare, G Valuri, R Woodman, A Ferrante, D Castle and A Jablensky

This study investigated the correlation between socio-structural characteristics of postcodes and the prevalence of (a) arrest, (b) schizophrenia diagnosis and (c) the joint prevalence of schizophrenia diagnosis and arrest.



This study found a high prevalence of general population arrest in Western Australia: 14.4 percent of the population had been arrested over a 12-year period. The prevalence of schizophrenia was low, and the joint prevalence of having a diagnosis of schizophrenia and an arrest, at 0.1 percent, was rarer still.

The same area-level characteristics that generate high arrest rates for the population as a whole also generate high arrest rates for people with schizophrenia. These include: disadvantage, inequality, ethnic homogeneity and residential mobility. There is no evidence of a multiplier effect.

However, compared to the general population, individuals with schizophrenia are more likely to be exposed to social disadvantage and other neighbourhood-level risk factors that predict offending in non-psychotic populations. For example, the first and second Australian national psychosis surveys have found that the life histories of people with psychosis are marked by long-term educational and economic disadvantage, homelessness, social marginalisation, and levels of victimisation were well above population levels. Therefore it is likely that a large component of the risk of offending in persons with schizophrenia stems from their living circumstances rather than as a direct consequence of their mental health status.

These findings have important implications for policy and program development in both criminal justice and mental health. They suggest that geographic areas characterised by high levels of social disorganisation require more investment in crime prevention, mental-health services and criminal justice responses.

http://www.aic.gov.au/documents/C/0/8/%7BC0878787-6326-44B4-9F32-71F0B8A2A596%7Dtandi365.pdf

Service utilisation projects in collaboration with WA Centre for Mental Health Policy Research

Study 1. Patterns of service use for people who have had a psychiatric inpatient admission

G Smith, T Williams, V Morgan, A Jablensky, D Young

This project has constructed a database for exploring inpatient demand within the mental health system. Its aim is to determine groups/subgroups of persons who use inpatient services based on their socio-demographic and clinical characteristics and identify trends and changes in patterns of care over time. A key objective is to use the data to identify existing and potential strategies for reducing demand on inpatient services.

Study 2. Long-term treatment outcomes in early psychosis specialist services

G Smith, T Williams, V Morgan, D Young

The aim of this study has been to evaluate the long-term effects of treatment in a specialist early intervention in psychosis (EIP) service—specifically, whether people in an EIP service have better short- and long-term outcomes when compared with people in standard treatment services. The study will obtain up to 10 years of data on people in the Bentley and Rockingham/ Kwinana specialist EIP services and a matched comparison control group that has received standard




treatment in generic mental health services in metropolitan Perth. The study uses a retrospective design, with the key outcome measures including psychiatric admissions, time to re-admission, service use and death.


METHODOLOGIES and APPROACHES

Record linkage across population-based registers

The Neuropsychiatric Epidemiology Research Unit has extensive experience in the use of multigenerational cross-linked data from the Western Australian psychiatric case register, State health (e.g. morbidity, birth defects, midwives, mortality) and other registers (e.g. criminal; intellectual disability; cerebral palsy; cancer; child protection and education) to study prevalence, incidence, aetiology and risk factors. To the end, it has established an e-Cohort of high risk children born to mothers with schizophrenia and other psychoses. Unit researchers are expert at designing and developing sophisticated hierarchical data models for linking, interrogating and analysing data across registers and through generations. Operationalising and validating key constructs using register data (e.g. diagnosis; neonatal encephalopathy; socioeconomic status; adversity) is a priority.


Risk factor epidemiology

Record linkage methodology has been the basis of the epidemiological study of risk factors for schizophrenia and other psychosis. These have included: obstetric complications; influenza; and season of birth.


Multigenerational approach

In work utilising the e-Cohort of high risk children of mothers with psychosis, the focus has been on the role of genetic and environment risk factors, and their interaction, in the onset of schizophrenia and other psychoses. Sibships among offspring have been constructed and determination of the family relationship (for example, full sibling or half sibling) is possible. Some children have become parents themselves, so we are now collecting data for three generations. A sophisticated hierarchical data model has been implemented to reflect the multiple relationships in the data

Survey-based research

The Neuropsychiatric Epidemiology Research Unit is experienced in the design, instrument development and coordination of large national multisite surveys and the Unit includes highly skilled research staff with clinical mental health expertise. It has had responsibility for the conduct of Australia’s two national psychosis surveys: in 1997-98, the first national survey of psychosis, the Low Prevalence (Psychotic) Disorders Study and, in 2010, the second national Survey of High Impact Psychosis (SHIP). In 2012, it began work on a SHIP extension study in north metropolitan Perth, the North Metro Survey of High Impact Psychosis (North Metro SHIP).









In 2012, the Unit was awarded a large NHMRC grant to follow up Western Australian SHIP North Metro SHIP participants in order to determine factors associated with changes in cardiometabolic profiles in people with severe mental illness, examine impediments to risk modification, and develop targeted interventions for implementation within mental health services

Clinical casenotes review

Register data are supplemented by psychiatric data extracted from clinical casenotes by experienced mental health clinical professionals. Several instruments have been developed for this purpose including an adaptation of the Diagnostic Interview for Psychosis for use with children’s casenote data, and the Children’s Checklist that was developed internally specifically for the collection of data for children on substance misuse, psychotropic medication use, behavioural problems, neurocognitive data and psychopathology not recorded in the Diagnostic Interview for Psychosis.



INSTRUMENT DEVELOPMENT

Diagnostic Interview for Psychosis (full versions: LPDS and SHIP)

The Diagnostic Interview for Psychoses (DIP) is a semi-structured interview for psychoses for use in epidemiological and clinical settings. It is designed to provide a diagnosis, as well as to assess symptom profiles (present state, past year and lifetime), social functioning, disablement, service utilisation and need. The DIP was developed specifically for the Low Prevalence (Psychotic) Disorders Study (LPDS) 1997-98 and greatly expanded for the Survey of High Impact Psychosis (SHIP) 2010. A Diagnostic Module, described separately below, is central to the DIP. The revised (SHIP) version includes modules on: social demographics; education; employment; housing; finances; activities of daily living; child care; caring; socialising; self harm; victimisation and offending; satisfaction with life; inpatient treatment; emergency/casualty treatment; outpatient treatment; public community mental health; community rehabilitation and day therapy; general practice service; non government agencies; medication use; mental health care & unmet need; other psychopathology and cognition; drug and alcohol use and smoking, and physical health.

Diagnostic Interview for Psychosis – Diagnostic module (DIPpc-DM 1.0)

The Diagnostic Module of the Diagnostic Interview for Psychoses (DIP-DM) is a semi-structured interview consisting of the 97 items of the Operational Criteria For Psychosis (OPCRIT). The DIP_DM uses probes and differential definitions derived and adapted from the WHO Schedules for Clinical Assessment in Neuropsychiatry (SCAN). A computer algorithm has been written to generate diagnoses using the underlying Operational Criteria For Psychosis (OPCRIT) algorithm. The development, reliability and applications of the DIP have been published. The DIP-DM is being used in New Zealand, UK, US and, in translation, in Indonesian, Italy, Spain, France, Greece, Norway, Mongolia, Russia and Bulgaria. A self-executing PC version of the software was developed and distributed in 2013.


Psychosis Screen

The Psychosis Screen was developed specifically for the Low Prevalence (Psychotic) Disorders Study 1997-98 and further modified for the Survey of High Impact Psychosis 2010. It is a brief instrument (one page) covering 8 items and takes 1-2 minutes to complete. There are patient and keyworker versions.

Brief Cognitive Assessment Tool

As part of the Survey of High Impact Psychosis 2010, a need was identified for a Brief Cognitive Assessment Tool that could be used in a number of research settings. In 2009, the assessment tool was completed and psychometric properties were examined. The tool was employed successfully in the 2010 Survey of High Impact Psychosis (SHIP) and the 2012 North Metro SHIP.




McNeil-Sjöström Scale for Obstetric Complications

The McNeil-Sjöström Scale operationalises the scoring of hundreds of obstetric complications and their treatment, including the range of potential complications from common to rare. The scale is underpinned by both biological and aetiological considerations and is designed to take a better account of the amount, timing and severity of obstetric complications. It produces separate summated scores indicating the number of complications of a particular severity level for each of three time periods (pregnancy, labour and delivery, and the neonatal period) as well as producing an overall score. A computer algorithm automates the scoring of obstetric complications recorded on the electronic Midwives Database.

Measures of longitudinal maternal morbidity

Algorithms have been written using all longitudinal maternal health data available on the Midwives Database to produce a full estimate of maternal morbidity at the time of childbirth.

Measures of adversity

Indicators of exposure to adverse life events and adverse social, familial and physical environments are being systematically extracted from the linked electronic records. These indicators will be combined in clinically and mathematically meaningful ways that will allow them to be used as predictors of outcome in our risk factor research.

Children’s Checklist

Children’s Checklist is an instrument developed within the Unit specifically for the collection of children’s data on substance misuse, psychotropic medication use, behavioural problems, neurocognitive data and psychopathology not recorded in the Diagnostic Interview for Psychosis.

Instrument validity and reliability

Testing the psychomteric properties of instruments used and/or developed including their validity and inter-rater reliability where appropriate, and assessing the reliability and validity of key constructs is an ongoing priority for the Unit.


STAFF 2013

Prof Vera Morgan Professor Head: Neuropsychiatric Epidemiology Research Unit, UWA School of Psychiatry and Clinical Neurosciences

Deputy Director (Epidemiology): UWA Centre for Clinical Research in Neuropsychiatry

Operational Epidemiologist: North Metropolitan Health Services Mental Health

Prof Assen Jablensky Winthrop Professor Senior Scientific Consultant

Director: UWA Centre for Clinical Research in Neuropsychiatry

Dr Kate Brameld Assistant Professor Epidemiologist

Dr Maxine Croft Assistant Professor Epidemiologist / Biologist

Ms Patsy Di Prinzio Research Associate Statistician

Ms Jenny Griffith Project Manager North Metro SHIP deputy coordinator / Mental Health Clinical Research Nurse

Dr Sonal Shah Assistant Professor Data analyst (SHIP Survey) / Clinical Research Psychologist

Ms Giulietta Valuri Assistant Professor Epidemiologist / Criminologist

Ms Anna Waterreus Assistant Professor National Coordinator for SHIP Survey / North Metro SHIP coordinator / Coordinator SHIP WAve2

North Metro SHIP Survey

Additional Interviewers: John DeanRochelle JonesKim PedlerMike Sommer

Data entry: Hannah Castle

Software development: Matt Walsh


RESEARCH FUNDING RECEIVED/COMMITTED 2012 ONWARDS ($)

Funding Source

Investigators

Study Title 2012 2013 2014 2015 2016 2017 2018

UWA Faculty of Medicine, Dentistry and Health Sciences Near Miss Grant

Croft M Healthy pregnancy outcomes for mothers with severe mental illness needing psychotropic medications during pregnancy

70,000

NHMRC APP1064582

Jablensk AMoses EMcCarthy NMelton PDragovic MMorgan VBadcock JWaters F

Schizophrenia under the genomic lens: next generation sequencing of Western Australian families with schizophrenia

423,437

178,437

358,437

NH&MRC APP1046729

Morgan VJablensky AWatts GBadcock JCox KStefanis N

Overcoming barriers to improved physical health in people with severe mental illness

228,912

233,787

233,787

133,983

NHMRC Partnership Grant APP1028554

Austin M-PSullivan EHighet NMorgan VMihalopoulos CCroft M

The Australian perinatal mental health reforms: using population data to evaluate their impact on service utilisation and related cost-effectiveness

NHMRC

beyondblue partnership

184,040

120,085

162,340

120,085

162,340

120,085


Funding Source

Investigators

Study Title 2012 2013 2014 2015 2016 2017 2018

WA Dept of Health

Morgan V North Metropolitan Survey of High Impact Psychosis Extension contract

167,625

WA Dept of Health

Morgan V North Metropolitan Survey of High Impact Psychosis

Continuing from 2011

344,850

114,950

NH&MRC APP1002259

Jablensky AMorgan VMcNeil TAbel KMorgan F

Life course trajectories and neuro-psychiatric outcomes in an e-cohort of high risk children of mothers with psychosis

Continuing from 2011

304,701

191,073


PUBLICATIONS 2013

*Only publications related to the work of the unit are included. A person may have publications in other research areas.

Journal Articles

Brameld KJ, Dye DE, Maxwell S, Brisbane JM, Glasson EJ, Goldblatt J, O’Leary P. The Western Australian Family Connections Genealogical Project: detection of familial occurrences of single gene and chromosomal disorders. Genetic Testing and Molecular Biomarkers, accepted October 2013Foley D, Mackinnon A, Morgan VA, Watts G, McGrath J, Castle D, Waterreus A, Galletly C. Predictors of type 2 diabetes in a nationally representative sample of adults with psychosis. World Psychiatry, 2013, accepted 27 Dec 2013Foley D, Mackinnon A, Watts G, Shaw J, Magliano D, Castle D, McGrath J, Waterreus A, Morgan VA, Galletly C. Cardiometabolic risk indicators that distinguish adults with psychosis from the general population, by age and gender. PLoS ONE, 2013, 8, e82606.Morgan VA. Strategies for improving employment outcomes for people with psychosis. Commentary on: Severe mental illness and work – What can we do to maximise employment opportunities for individuals with psychosis? Australian and New Zealand Journal of Psychiatry, 2013, 47, 486-487.Morgan VA, McGrath J, Jablensky A, Badcock JC, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, Hocking B, McGorry P, Neil A, Saw S, Shah S, Stain H, Mackinnon A. Psychosis prevalence and physical, metabolic and cognitive comorbidity. Data from the second Australian national survey of psychosis. Psychological Medicine, FirstView, 1-14, doi:10.1017/S0033291713002973Morgan VA, Morgan F, Valuri G, Ferrante A, Castle D and Jablensky A. A whole-of-population study of the prevalence and patterns of criminal offending in schizophrenia and other psychiatric

disorders. Psychological Medicine, 2013, 43, 1869 - 1880Power B, Stefanis N, Dragovic M, Jablensky A, Castle D, Morgan VA. Age at initiation of amphetamine use and age at onset of psychosis: the Australian Survey of High Impact Psychosis. Schizophrenia Research, 2013, doi: http://dx.doi.org/10.1016/j.schres.2013.11.003

Neil A, Carr V, Mihalopouls C, Mackinnon A, Lewin T, Morgan VA. What difference a decade? The costs of psychosis in Australia in 2000 and 2010: comparative results from the first and second Australian National Surveys of Psychosis. Australian and New Zealand Journal of Psychiatry, 2013, online preprint Nov 12, 2013Neil A, Carr V, Mihalopouls C, Mackinnon A, Morgan VA. Costs of psychosis in 2010: findings from the second Australian National Survey of Psychosis. Australian and New Zealand Journal of Psychiatry, 2013, online October 4, 2013O’Donnell M, Anderson D, Morgan VA, Nassar N, Leonard H, Stanley F. Trends in pre-existing mental health disorders among parents of infants born in Western Australia from 1990 to 2005. Medical Journal of Australia, 2013, 198, 485-488.Raudino A, Carr V, Bush R, Saw S, Burgess P, Morgan VA. Patterns of health service utilisation. Results from the second Australian national survey of psychosis (SHIP). Australian and New Zealand Journal of Psychiatry, 2013, online preprint November 12, 2013Sodhi-Berry N, Preen D, Alan J, Knuiman M, Morgan VA. Pre-conviction mental health service use in adult offenders in Western Australia: Baseline results from a longitudinal whole-population cohort study. Criminal Behaviour and Mental Health, 2013, accepted 30 December 2013 Stefanis NC, Milan Dragovic M, Power BD, Jablensky A , Castle D, Morgan VA. Age at initiation of cannabis use predicts age at


onset of psychosis: The 7-8 year trend. Schizophrenia Bulletin, 2013, 39, 251-254

Books and ChaptersMorgan VA, Keefe R, Kahn RS, Malhotra AK, Meyer-Lindenberg A, Mueser KT, Nikolich K, Rössler W, Spaulding W, Sritharan S and Wyke T. What is necessary to enhance development and utilization of treatment? In Silverstein, S. M., B. Moghaddam, and T. Wykes (eds). Schizophrenia: Evolution and Synthesis. Strüngmann Forum Reports, vol. 13, J. Lupp, series ed. Cambridge, MIT Press, 2013, pages 273-305


Published abstractsMcGrath J, Galletly C, Waterreus A, Jablensky A, Mackinnon A, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S, Morgan VA, Comorbid physical illness in those with psychotic disorders; the Australian National Psychosis Survey. Schizophrenia Bulletin 2013, 39 Suppl 1, 35Morgan VA, Di Prinzio P, Shah S, Valuri G, Croft M, Jablensky A. The association between social adversity and psychosis in a whole-of-population cohort of high risk offspring of mothers with psychotic disorders. Schizophrenia Bulletin 2013, 39 Suppl 1, 71Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S. Psychosis prevalence, profile, comorbidity and cognition. Novel data from the Australian National Psychosis Survey. Schizophrenia Bulletin 2013, 39 Suppl 1, 71

Other publicationsMorgan VA, Marwick P, Waterreus A, Jablensky A, Rock D, Sultan L, Shah S, Di Prinzio P. North Metropolitan Health Service Survey of High Impact Psychosis (North Metro SHIP). Report to North Metropolitan Health Service Mental Health and Mental Health Commission. November 2013Waterreus A on behalf of the SHIP Study Group: SHIP GP Summary Report, 2013


ORAL CONFERENCE PRESENTATIONS 2013

Croft ML, Morgan V, Mc Neil T, di Prinzio P, Valuri G, Shah S, Jablensky A. Obstetric Complications and Infant Outcomes for the Offspring of Women with Schizophrenia in Western Australia. Australasian Society for Psychiatric Research Conference, Melbourne, 3-6 December 2013Croft ML, Morgan V, Mc Neil T, Valuri G, di Prinzio P, Shah S, Jablensky A. Reproductive pathology in women with psychosis. Australasian Schizophrenia Conference, Melbourne, 13-14 May 2013Morgan VA. Physical health and other outcomes in people with psychosis. Data from the National Survey of High Impact Psychosis (SHIP). TheMHS Summer Forum. Mental Disorders and Physical health: linking body and mind. Sydney, 21-22 Feb 2013. (Invited plenary)Morgan VA on behalf of the Survey of High Impact Psychosis study group. Modifiable risk factors for cardiometabolic disease: Data from the 2010 Australian national survey of psychosis. Australasian Schizophrenia Conference, Melbourne, 13-14 May 2013Shah, SM, V Morgan, A Mackinnon, C Galletly, H Stain, J McGrath, V Carr, D Castle, C Harvey, S Sweeney. Does childhood abuse impact on profile and outcome in people with a psychotic illness? Data from the second Australian national survey of psychosis. Australasian Schizophrenia Conference, Melbourne, 13-14 May 2013Valuri G, Jablensky A, Morgan F, Morgan V. Patterns of Offending in the Offspring of Mothers with Severe Mental Illness. Australasian Society for Psychiatric Research Conference, Melbourne, 4-6 December 2013


POSTER PRESENTATIONS 2013

Brameld K, Jablensky A, Griffith J, Dean J, Morgan V. Psychotropic medication and infant outcomes for the offspring of women with psychosis. Australasian Society for Psychiatric Research. Melbourne, Dec 4-6 2013.McGrath J, Galletly C, Waterreus A, Jablensky A, Mackinnon A, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S, Morgan VA, Comorbid physical illness in those with psychotic disorders; the Australian National Psychosis Survey. International Congress on Schizophrenia Research, Orlando, USA 1-4 Apr 2013Morgan VA, Di Prinzio P, Shah S, Valuri G, Croft M, Jablensky A. The association between social adversity and psychosis in a whole-of-population cohort of high risk offspring of mothers with psychotic disorders. International Congress on Schizophrenia Research, Orlando, USA 1-4 Apr 2013Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S. Psychosis prevalence, profile, comorbidity and cognition. Novel data from the Australian National Psychosis Survey. International Congress on Schizophrenia Research, Orlando, USA 1-4 Apr 2013Waterreus A, Di Prinzio P, Morgan V, Galletly C. Treating body, treating mind: the challenges for GPs. Findings from the Australian National Survey of High Impact Psychosis. Australasian Schizophrenia Conference, Melbourne, Australia 13-14 May 2013


OTHER TALKS AND PRESENTATIONS 2013

Maxine Croft Invited presentation. First do no harm…. but how will we know what causes harm? An overview of selected research within the Neuropsychiatric Epidemiology Research Unit of the School of Psychiatry and Clinical Neurosciences. Royal Perth Hospital Psychiatry Research Forum. 26 March 2013

Vera Morgan Invited panel member. National Ministerial Summit Addressing Premature Death of People with Mental Illness. Sydney, 24 May 2013

Vera Morgan Invited lecture. Data Linkages. PSYC5530:Applied Research Methods for Postgraduate Students in Clinical Psychology and Clinical Neuropsychology, UWA School of Psychology. 22 May 2013

Vera Morgan Invited lecture. Writing to be read. Research Methods: Master of Criminal Justice course, Crime Research Centre, University of Western Australia. 18 May 2013

Vera Morgan Invited lecture series: Unravelling risk factors for schizophrenia and other neuropsychiatric outcomes. A Western Australian record-linkage research program / Criminal offending and victimisation in people with psychosis / Psychosis prevalence and comorbidity. Data from the Australian national psychosis survey. Tromsø University 23-24 October 2013

Anna Waterreus Invited presentation. The Survey of High Impact Psychosis. The University of Notre Dame, School of Nursing & Midwifery Fremantle. March 2013

Giulietta Valuri Invited presentation. Psychosis and Crime. Royal Perth Hospital Psychiatry Research Forum. 28 May 2013.


POSTGRADUATE STUDENTS 2013

Student Degree Topic Dates NERU superviser

Supervisor(s)

G. Valuri PhD Criminal offending, victimization and schizophrenia

Started part-time 27 June 2011 (8 yrs p/time)

Prof Vera Morgan

VA Morgan (co-ordinating)FH MorganAJ Jablensky

C. Harrison PhD Epidemiology of cardiovascular disease risk factors in the psychiatric population of WA

Started part-time 2009 (8 yrs p/time)

Prof Vera Morgan

VA Morgan (co-ordinating)M DragovicAJ JablenskyJ Laugharne

T. Major M.Biostats

“Reproductive pathology and obstetric complications in a cohort of women with schizophrenia.” Workplace placement project.

Started part-time 2013 (course commenced part-time 2004)

Assist Prof Maxine Croft, Prof Vera Morgan

J Henstridge (co-ordinating)


RESEARCH COLLABORATIONS AND ACTIVITIES 2013

International

External Collaborators

Affiliation NERU collaborators

Area of collaboration

Outcomes 2013

Prof Tom McNeil University of Lund, Sweden

All Developmental pathways for the children of women with severe mental illness

Ongoing collaborationAdvice on changes to the McNeil-Sjöström ScalePaper in early neurodevelopmental outcomes in progress

Prof Jonas Bjork University of Lund, Sweden

All Developmental pathways for the children of women with severe mental illness

Ongoing collaborationPaper in early neurodevelopmental outcomes in progress

A/Prof Kathryn Abel University of Manchester, UK

V MorganM Croft

Obstetric complications in women with severe mental illness

Paper on mortality outcomes for offspring of women with severe mental illness in preparation

Prof Vidje Hansen, Dr Ingunn Skre

Institute for Psychology, University of Tromsø. Norway

A JablenskyV Morgan

Validation of Norwegian translation of the Diagnostic Interview for Psychosis.Successful Norwegian grant application

2013-2015. Norwegian Council of Research. Application 9053-33047. Phenotypes of severe mental illness - association with genetic variantsLecture series, University of Tromsø

C Morgan, M Cannon, W Veling, E Susser (discussant)

Institute of Psychiatry, Royal College of Surgeons in Ireland, Parnassia Psychiatric Institute/ Maastricht University, Columbia University

V Morgan Adversity and psychosis

Poster Symposium at the 2013 International Congress on Schizophrenia Research, Orlando on “Perspectives on social adversity and psychosis". Presenters: C Morgan, M Cannon, W Veling, V Morgan (chair), E Susser (discussant).


National

External Collaborators Affiliation NERU collaborators


Outcomes 2013

Prof Stan Catts Psychosis Australia Trust

V MorganA Jablensky

Psychosis research network

Executive committee member

Prof John McGrath University of Queensland

V MorganA Jablensky

Environmental risk factors for schizophrenia

Meetings 2012

Survey of High Impact Psychosis (SHIP) Technical Advisory Committee: Prof Robert Bush Prof Vaughan Carr Prof David Castle Assoc. Prof Cherrie Galletly Prof Carol Harvey Barbara Hocking Prof Assen Jablensky Prof John McGrath Prof Andrew MackinnonProf Pat McGorry Prof Vera Morgan (Chair)Dr Amanda Neil Dr Helen StainAssist. Prof Anna Waterreus

Universities and health services in WA, NSW, QLD, SA, VIC

V MorganA JablenskyA WaterreusJ Griffith

Survey of High Impact Psychosis (SHIP)

Publications in progress

A/Prof Nadia Badawi

Dr John Keogh

University of Sydney / The Children's Hospital at WestmeadConsultant Obstetrician and Gynaecologist, Sydney Adventist Hospital

M Croft Revisions of McNeil Sjöström Scale (Perth version)Validation of neonatal encephalopathy

Protocol developed for cerebral palsy study

Development of algorithm for neonatal encephalopathy

Revision of McNeil Sjöström Scale (Perth version)

SANE Australia A WaterreusV Morgan

Survey of High Impact Psychosis (SHIP)

Brochure for stakeholders

Membership of Clinical Expert Advisory Group


State

External Collaborators Affiliation NERU collaborators


Outcomes 2013

Dr Eve BlairJan de GrootLinda Watson

Institute for Child Health Research

M Croft Validation of the Australian version of the McNeil Sjöström Scale Scoring System using clinical case notes from the Cerebral Palsy International Case Control Study.

Protocol for validation has been developed and scores have been calculated for all children with cerebral palsy.

A/Prof Frank MorganAnna Ferrante

University of WA Crime Research Centre

V MorganG ValuriA Jablensky

Offending patterns and psychiatric illness

Article in print

A/Prof Frank Morgan University of WA Crime Research Centre

V MorganG Valuri

Victimisation and offending in people with psychosis

Paper in preparation

Prof David PreenProf Matt KnuimanNita Sodhi-Berry

University of WA Population Health

V Morgan Mental illness and crime

Publications submitted and in press

Dr Melissa O'Donnell Institute for Child Health Research

V Morgan Parental mental illness

Article in print

Prof Carol BowerProf Steve Zubrick

Institute for Child Health Research

All Environmental risk factors and developmental pathways in schizophrenia

Joint conference presentations and papers

A/Prof Geoff SmithA/Prof Theresa Williams

Dept of Health Western Australia

V MorganA Jablensky

Study of High Users of Psychiatric Services

Report submitted

A/Prof Geoff SmithA/Prof Theresa Williams


V Morgan Long-term outcomes of early intervention in psychosis

Report submitted

Dept of Health Western Australia (North Metro)

NMHS MH Health Data Informatics Committee

V Morgan Operational epidemiology

NMHS MH Health Data Informatics Committee member

Dept of Health Western Australia (North Metro)

Dept of Health Western Australia / Mental Health Commission

V MorganA WaterreusJ GriffithA JablenskyN Stefanis

Operational epidemiology

North Metro SHIP survey

Dept of Health Western Australia (North and South Metro)


V MorganA WaterreusJ GriffithA JablenskyN Stefanis

Operational epidemiology

SHIP WAve2 study

Prof A Jablensky* Centre for Clinical Research in Neuropsychiatry

A Jablensky* WA Family Study of Schizophrenia

Joint work on linked data for study participants / NHMRC grant applications

Prof Jonathan Rampono Health Department of Western Australia

M Croft Perinatal and infant mental health

Model of Care document


* A Jablensky appears as both external and internal NERU collaborator for those projects that straddle his dual roles as Senior Scientific Consultant: Neuropsychiatric Epidemiology Research Unit and Director: Centre for Clinical Research in Neuropsychiatry


STAFF: AWARDS AND PRIZES 2013

UWA Faculty of Medicine, Dentistry and Health Sciences Near Miss Grant Maxine Croft

STAFF: FORMAL OFFICES HELD 2013

Board of Management (casual member and Board representative on the Scientific Advisory Committee)

SIDS and Kids WA Maxine Croft

STAFF: CONFERENCE ORGANISING COMMITTEES 2013

Member, Scientific Committee

Australasian Society for Psychiatric Research

Vera Morgan

Member, International Program Committee

Schizophrenia International Research Society

Vera Morgan

STAFF: EDITORIAL COMMITTEES 2013

Member, Advisory Board

Australian and New Zealand Journal of Psychiatry

Vera Morgan

Member, Editorial Board

Social Psychiatry and Psychiatric Epidemiology

Vera Morgan


STAFF: OTHER COMMITTEE MEMBERSHIP 2013

Honorary Member Information Technology Reference Group for Ngala, WA

Maxine Croft

Researcher representative

School of Psychiatry and Clinical Neurosciences: Research

Maxine Croft

Chair North Metro Survey of High Impact Psychosis (North Metro SHIP)Technical Advisory Group

Vera Morgan

Chair National Survey of High Impact Psychosis (SHIP) Study Group

Vera Morgan

Member North Metropolitan Area Health Service Mental Health Data Management Working Group

Vera Morgan

Committee member

Intellectual Disability Exploring Answers (IDEA) Advisory Council and Ethics Committee

Vera Morgan

Committee member

School of Psychiatry and Clinical Neurosciences: Research, Publications and Postgraduate Studies Committee

Vera Morgan

Member Schizophrenia Research Institute (NSW): Epidemiology and Population Health Panel

Vera Morgan

Member The Mental Health Needs of WA Reception Prisoners Steering Group

Vera Morgan

Member Psychosis Australian Trust Research Committee

Vera Morgan

Member National Health and Medical Research Council Assigners Panel

Vera Morgan

Member National Health and Medical Research Council Practitioner Fellowships Peer Review Panel

Vera Morgan

Member SANE Australia Clinical Expert Advisory Group

Vera Morgan

Webmaster Australasian Society for Psychiatric Research

Giulietta Valuri

Member North Metro Survey of High Impact Psychosis (North Metro SHIP) Technical Advisory Group

Anna Waterreus


Member National Survey of High Impact Psychosis (SHIP) Study Group

Anna Waterreus


STAFF: CURRENT PROFILE

Kate Brameld BSc(Hons) PhD

EPIDEMIOLOGIST: Neuropsychiatric Epidemiology Research Unit/ Adjunct Senior Research Fellow, Centre for Population Health Research, Curtin Health Innovation Research Institute (CHIRI), Curtin University+61 8 9224 [email protected]

Kate Brameld has extensive experience in epidemiology and health services research and advanced methodological and statistical skills in the analysis of linked data. Her doctoral research developed techniques for the estimation of incidence and prevalence and study of patterns of care from longitudinal linked data following which she researched the effect of socio-demographic factors on the health care experience of patients with chronic disease. She has since been involved in the development, monitoring and evaluation of policy related to prevention and treatment of genetic disease and in clinical governance in a local mental health service.

Research interests Methods in the analysis of linked data Socio-demographic factors and health Mental illness & Recovery


Maxine CROFT BAppSc PhD

EPIDEMIOLOGIST / BIOLOGIST: Neuropsychiatric Epidemiology Research Unit/ Honorary Research Fellow, Centre for Child Health Research, University of Western Australia+61 8 9224 [email protected]

Maxine Croft is a computer scientist and epidemiologist who has been a consultant to WHO on database design. As a consultant to the Federal government on diabetes research, she proposed the (now accepted) recording of Medicare numbers on PBS prescriptions. Her doctoral research resulted in creation of the WA Twin Child Health registry and she uses linked population data to measure risk of recurrence of reproductive outcomes. She has modified an electronic version of the McNeil Sjöström scoring system to include a broader range of maternal diseases. This Perth version will also include longitudinal measures of maternal chronic disease.Research interests Perinatal epidemiology Schizophrenia Longitudinal measures of maternal health Obstetric complications Database management


Patsy Di PRINZIOBSc(Hons) BAppSci

STATISTICIAN: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Patsy Di Prinzio is a statistician with high level mathematical and statistical computing skills and excellent written communication abilities. She has extensive knowledge of most appropriate statistical techniques to analyse a wide range of data and the ability to present resultant information in a form which is most accessible to broad audiences. Her experience includes consulting in applied statistics in private, government, and university sectors, as well as teaching experience in government and university.

Research interests Applied statistics Epidemiology of schizophrenia and other

psychotic disorders Automation of data management, analysis

and results presentation as a linked process

Jenny GRIFFITH RN RMHN BAAppSc(Nursing) GradDipArtsCounselling PGDipMentalHealthNursing

WA SITE COORDINATOR FOR NATIONAL SHIP SURVEY / DEPUTY COORDINATOR FOR NM SHIP / MENTAL HEALTH CLINICAL RESEARCH NURSE: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Jenny Griffith is Deputy Coordinator for North Metro Survey of High Impact Psychosis (SHIP). She was WA site Coordinator for National SHIP. Jenny was an interviewer in the 1998 National Survey of Low Prevalence (Pyschotic) Disorders. Since 2004, she has also managed the collection of qualitative mental health data in the Pathways study, including the review of clinical casenotes, to complete the Diagnostic Interview for Psychosis (DIP), the Children’s Checklist and Life Histories.

Research interests Adversity and children with a mentally ill

parent Severe mental illness Metabolic syndrome Role of mental health nurses in research


Assen JABLENSKY MD DMedSc FRCPsych

FRANZCPsych

SENIOR SCIENTIFIC CONSULTANT: Neuropsychiatric Epidemiology Research Unit / DIRECTOR: Centre for Clinical Research in Neuropsychiatry+61 8 9224 [email protected]

Assen Jablensky completed his medical degree and training as a psychiatrist in Bulgaria and the UK, and has worked as a researcher and clinician in Switzerland (WHO, Geneva), the US (Stanford University) and, since 1993, Australia, where he is director of the Centre for Clinical Research in Neuropsychiatry of the University of Western Australia in Perth. He has over 290 publications, including articles in peer-reviewed journals, book chapters and monographs. He has been award the Strömgren Prize and medal for psychiatric epidemiology; the Australasian Society for Psychiatric Research Founders Medal, the Organon Senior Research Award, and several other distinctions including Honorary Fellowship of the Royal College of Psychiatrists (UK).

Research interests psychiatric epidemiology genetics of schizophrenia classification of mental disorders

Vera MORGAN BA GradDipEd MSocSc PhD

HEAD: Neuropsychiatric Epidemiology Research Unit / DEPUTY DIRECTOR (EPIDEMIOLOGY): Centre for Clinical Research in Neuropsychiatry+61 8 9224 [email protected]

Vera Morgan is a psychiatric epidemiologist with a special interest in studying schizophrenia and other psychotic disorders using record-linkage and survey methods. Her cross-disciplinary approach to psychosis melds epidemiological, psychiatric, sociological and criminological perspectives on aetiology, course and outcome to help unravel its complex nature. Her current program of research focuses on environmental and genetic contributions to the risk of schizophrenia, as well as physical health comorbidity, including metabolic syndrome and cardiovascular disease, in people with psychotic illness. She was National Project Director and Convenor: Technical Advisory Group for the National Survey of High Impact Psychosis. Her professional roles have included President: Australasian Society for Psychiatric Research, Vice-President: Australasian Epidemiological Association, Chair: Research Committee of the Mental Health Council of Australia and Member: The University of Western Australia Senate.

Research interests Epidemiology of schizophrenia and other

psychoses


Risk factor epidemiology Cardiometabolic disease and

psychotic illness

Intellectual disability/cognitive deficit and psychotic disorders

Criminal offending and mental illness


Sonal SHAH PhD BSC(HonsPsych)

DATA ANALYST (SHIP SURVEY) / CLINICAL RESEARCH PSYCHOLOGIST: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]

Dr Shah's main interest and research focus is in the identification of adverse risk factors associated with schizophrenia. Within the Pathways project, her aim is to investigate outcomes for offspring of mothers with schizophrenia using both register data and clinical casenotes. She has developed an effective method for the manual mapping of affected children's life histories using register and clinical casenotes data. She also plays a key role in the management and analysis of data for the national Survey of High Impact Psychosis (SHIP), North Metro SHIP and SHIP Wave2. Prior to her work in NERU, Sonal was involved in a large study (as part of her PhD project) investigating hormonal and non hormonal factors associated with cognitive function. An important and novel finding of this project was the association between circulating androgen levels and cognitive function. She was awarded the AMS award for the most meritorious contribution to the field of menopause in 2006 and best overall

Giulietta VALURI BBus GradDipEpi EPIDEMIOLOGIST / CRIMINOLOGIST: Neuropsychiatric Epidemiology Research Unit+61 8 9224 [email protected]


Giulietta Valuri is a computer scientist and an epidemiologist who has worked in injury prevention research and with linked WA population databases in both criminology (patterns of offending) and mental health. Her research has included validating mental health diagnoses and studying patterns of offending in people with a mental illness. Her current research focuses on measuring and mapping children’s health status using WA data from linked statewide health registers and constructing offending profiles for these children using criminal offending data. Her expertise is in the areas of database management and design, and analytical techniques.

Research interests Epidemiology of schizophrenia and

other psychotic disorders High risk children of parents with

severe mental illness Criminal offending and mental

illness


Anna WATERREUS DipNursingStudies NZRN GradDipClinEpid

COORDINATOR FOR SHIP WAve2: Neuropsychiatric Epidemiology Research Unit+61 8 9347 [email protected]

Anna Waterreus is a Nurse who has a Post Graduate Diploma in Clinical Epidemiology and has been involved in psychiatric research for the last 25 years. Currently she is the Coordinator for the Survey of High Impact Psychosis WAve2. She was also involved in the first and second Australian surveys of psychosis (the Low Prevalence (Psychotic) Disorders Survey and the Survey of High Impact Psychosis (SHIP) and the North Metro SHIP study). Previously she worked in Old Age Psychiatry, UWA and the Institute of Psychiatry London and has an interest in depression in general practice and the role of nurses in metabolic syndrome.

Research interests Metabolic syndrome Mental health surveys Mental health nursing Depression & old age


Stephanie Gee (Senior Administrative Officer)


NERU Location and contact details

Neuropsychiatric Epidemiology Research UnitSchool of Psychiatry & Clinical Neurosciences

University of Western Australia M571Level 3, Medical Research Foundation (MRF) Building,

Rear 50 Murray StreetPerth

Western Australia 6000

Orange zone No. 5 on the map below.

Contact detailsMs Stephanie Gee

PH: +61-(0)8-9224-0290 FAX: +61-(0)8-9224-0285

EMAIL: [email protected]


MRF Building is orange zone no. 5

54

APPENDIX 1a. Research Funding 2004-2011 ($)

Funding CIs Study Title 2004 2005 2006 2007 2008 2009 2010 2011

WA Dept of Health

Morgan V North Metropolitan Survey of High Impact Psychosis

550,000

Also

funded in2012, 2013

NH&MRC APP1002259

Jablensky AMorgan VMcNeil TAbel KMorgan F

Life course trajectories and neuropsychiatric outcomes in an e-cohort of high risk children of mothers with psychosis

274,701

Also

funded in2012, 2013

Aust. Govt. Dept of Health and Ageing

Morgan VJablensky A

National survey of high impact psychosis (SHIP): Phase 3

3,300,000

1,928,097

148,904


Morgan VJablensky A

National survey of high impact psychosis (SHIP): Phase 2

606,903

NH&MRC #513874

Jablensky AKalaydjieva LSegal MBadcock JWiltshire SPrice GMorgan V

Memory synaptic plasticity and gene networks in schizophrenia 113,50

0 454,250 242,750 272,750

March of Dimes Research Foundation#12-FY07-224

Jablensky AMorgan VBower CZubrick SCroft M

A population-based study of obstetric, developmental and neuropsychiatric outcomes in the offspring of women with severe mental disorders. Round 2

45,772 93,500 93,500


Morgan VJablensky A

Scoping a national survey of high impact psychosis (SHIP): Phase 1

78,006 78,006

Dept of Health of WA

Morgan VJablensky ASmith GWilliams T

Psychiatric inpatient services database 1990-2006

30,909


Funding CIs Study Title 2004 2005 2006 2007 2008 2009 2010 2011Dept of Health of WA

Morgan VJablensky ASmith GWilliams T

High Users of psychiatric inpatient services 1990-2006

21,818

NH&MRC #458702

Jablensky AMorgan V

Children of parents with mental illness: a population-based study

329,950

294,000 131,125

NH&MRC Jablensky AKalaydjieva LBadcock JKendler KMorgan, VRiley B

Genetics of cognitive impairment in schizophrenia

295,000

260,272

235,000

Criminology Research Council

Morgan FMorgan VJablensky AFerrante AValuri

Schizophrenia and offending: area of residence and the impact of social disorganisation and disadvantage

41,934

March of Dimes Research Foundation

Jablensky AMorgan VBower CZubrick S

A population-based study of obstetric, developmental and neuropsychiatric outcomes in the offspring of women with severe mental disorders. Round 1

55,806 154,386 52,309

NH&MRC Jablensky AMorgan V

Fetal origin of adult disease? A population-based study of the offspring of women with severe mental disorders

172,500

187,500 82,875

UWA Small Research Grant

Morgan V Psychiatric morbidity and mental retardation: A Western Australian record linkage study


APPENDIX 1b. Research Funding 1995-2003 ($)

Funding CIs Study Title 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003UWA Small Research Grant

Morgan V Psychiatric morbidity and mental retardation: A Western Australian record linkage study

14,000

Commonwealth Dept of Health and Aged Care

Jablensky A Follow-up to the Low Prevalence Disorders study 60,000 20,000

Stanley Foundation

Jablensky AZubrick SBower CMorgan VPreston N

Pathways of risk from conception to disease: A population-based study of the offspring of women with bipolar disorder and schizophrenia

111,307

110,426

NHMRC (PHRDC)

Jablensky ACastle DMorgan FFerrante A

Criminal behaviour as an outcome in schizophrenia

78,242 66,152 53,311

NHMRC (PHRDC)

Holman DJablensky AFazio SBass J

Population linkage studies of preventable comorbidity in people with mental illness

34,632 75,849 78,353

Commonwealth Dept of Health and Aged Care

Jablensky A Low Prevalence (Psychotic) Disorders study

523,000

Stanley Foundation

Jablensky AZubrick SBower CCastle D

Reproductive pathology in women with schizophrenia and bipolar affective disorder: An epidemiological & clinical study

40,343 65,141

Royal Perth Hospital Medical Research Foundation

Jablensky ACastle DPage APetterson B

Influenza epidemics and incidence of CNS disorders in Western Australia

18,311


APPENDIX 2. SELECTED PUBLICATIONS 1995-2012 (Epidemiology)

2012Journal ArticlesGalletly C, Foley D, Waterreus A, Watts G, Castle D, McGrath J; Mackinnon A, Morgan VA. Cardiometabolic risk factors in people with psychotic disorders: the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 753-761Morgan VA, Croft M, Valuri G, Zubrick S, Bower C, McNeil T and Jablensky A. Intellectual disability and other neuropsychiatric outcomes in high risk children of mothers with schizophrenia, bipolar disorder and unipolar major depression. British Journal of Psychiatry, 2012, 200, 282-289Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Saw S. People living with psychotic illness in 2010. The second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46 ,735-753.Waghorn G, Saha S, Harvey C, Morgan VA, Waterreus A, Bush R, Castle D, Galletly C, Stain H, Neil A, McGorry P, McGrath J. “Earning and learning” in those with psychotic disorders: the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 774-785Waterreus A, Morgan VA, Castle D, Galletly C, Jablensky A, Di Prinzio P, Shah S. Medication for psychosis - consumption and consequences. The second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 762-773Books and ChaptersMeadows G, Harvey C, Morgan VA. Singh B. Mental disorder in Australia. In Meadows G, Farhall J, Fossey E, Grigg M, McDermott F, Singh B (eds) Mental Health in Australia (3rd ed) Oxford University Press, 2012, pages 237-263.

Published abstractsGalletly CA, Foley DL, Waterreus A, Watts GF, Castle D, McGrath J, Mackinnon A & Morgan VA (2012). ABSTRACT. High rates of cardiometabolic risk factors in people with psychotic disorders. Schizophrenia Research 136, Supplement 1, S308.Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath JJ, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil AL, McGorry P, Hocking B & Saw S (2012). ABSTRACT. Novel data from a large population prevalence survey: A unique opportunity to inform psychosis research directions and mental health reform. Schizophrenia Research 136, Supplement 1, S73

Reports and other publicationsMorgan V. National psychosis survey: mapping use of services. New Paradigm 2012, Autumn, 30-36Waterreus A on behalf of the SHIP Study Group: SHIP Participant Summary Report, 2012Waterreus A on behalf of the SHIP Study Group: SHIP NGO Summary Report, 2012


2011Journal ArticlesMorgan VA, Valuri G, Croft M, Griffith J, Shah S, Young D and Jablensky A. Pathways of risk from conception to disease: The Western Australian Schizophrenia High Risk e-Cohort. International Journal of Epidemiology, 2011, 40, 1477-1485

Books and ChaptersAbel KM & Morgan VA. Mental illness, women, mothers and their children. In: Tsuang MT, Tohen M, Jones PJ (eds). Psychiatric Epidemiology (3rd Edition). New York. John Wiley & Sons, 2011, pp 483-515Jablensky A. Diagnosis and revision of the classification system. In: W Gaebel (ed) Schizophrenia: Current Science and Clinical Practice. Wiley-Blackwell, 2011, ch 1:1-30

Published abstractsMorgan V, Jablensky A, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, Hocking B, Mackinnon A, McGorry P, McGrath J, Neil A, Saw S, Stain H. The Australian national survey of the epidemiology of psychosis: aims and preliminary findings. Schizophrenia Bulletin 2011, 37, Suppl 1, 57

ReportsMorgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Saw S. People living with psychotic illness 2010. Report on the second Australian national survey. Canberra, Australian Government Department of Health and Ageing, November, 2011

2010Journal ArticlesCroft ML, Morgan VA, Read A, Jablensky AV. Recorded pregnancy histories of the mothers of singletons and the mothers of twins: a longitudinal comparison. Twin Research and Human Genetics. 2010, 13(6) Invited paperJablensky A. The diagnostic concept of schizophrenia: its history, evolution, and future prospects. Dialogues in Clinical Neuroscience 2010, 12(3):271-87Jablensky A. Psychiatry in crisis? Back to fundamentals. World Psychiatry 2010, 9(1):29Henderson S, Jablensky A. The Lundby Study. Aust N Z J Psychiatry. 2010 Jan;44(1):1-3 Kendler KS, Jablensky A (2010) Kraepelin's concept of psychiatric illness. Psychological Medicine 2010, 1 Sept:1-8 [epub ahead of print]Loughland C, Draganic D, McCabe K, Richards J, Nasir A, Allen J, Catts S, Jablensky A, Henskens F, Michie P, Mowry B, Pantelis C, Schall U, Scott R, Tooney P, Carr V. Australian Schizophrenia Research Bank: a database of comprehensive clinical, endophenotypic and genetic data for aetiological studies of schizophrenia. Aust N Z J Psychiatry. 2010 Nov;44(11):1029-35Morgan VA and Jablensky AV. From inventory to benchmark: quality of psychiatric case registers in research. British Journal of Psychiatry. 2010, 197, 8-10Rossi A, Morgan V, Amaddeo F, Sandri M, Grigoletti L, Maggioni F, Ferro A, Rigon E, Donisi V, Vailati Venturi V, Goria F, Skre I, Tansella M, and Jablensky A. Diagnosing psychotic disorders: reliability and applications of the Diagnostic Interview for Psychosis (DIP) Italian version. Epidemiologia e Psichiatria Sociale 2010, 19, 33-43Selten J-P and Morgan VA. Prenatal Exposure to Influenza and Major Affective Disorder. Bipolar Disorders. 2010, 12, 753–754 Selten J-P, Frissen A, Lensvelt-Mulders G, Morgan VA. Schizophrenia and 1957 Pandemic of Influenza: Meta-Analysis. Schizophrenia Bulletin, 2010, 36, 219-228 Young DJ, Bebbington A, de Klerk N, Bower C, Nagarajan L, & Leonard H (2011). The relationship between MECP2 mutation type and health status and service use trajectories over time in a Rett syndrome population. Research in Autism Spectrum Disorders,( 2010) 5(1), 442-449. IF: 2.267


Published abstractsMorgan VA on behalf of the SHIP Technical Advisory Group and Project Implementation Steering Group: Morgan V, Jablensky A, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, McGorry P, McGrath J, Stain H, Hocking B, Mackinnon A, Neil A, Saw S. Revisiting social breakdown syndrome: The Australian National Survey of High Impact Psychosis (SHIP). Schizophrenia Research 2010, 117, 314Selten J-P, Frissen A, Lensvelt-Mulders G, Morgan V. Schizophrenia and 1957 pandemic of influenza: Meta-analysis. Schizophrenia Research 2010, 117, 430

2009Journal ArticlesDowns J, Young D, de Klerk N, Bebbington A, Baikie G, Leonard H. Impact of scoliosis surgery on activities of daily living in females with Rett syndrome. J Pediatr Orthop. 2009 Jun, 29(4) 369-74. Jablensky A. Towards ICD-11 and DSM-V: issues beyond 'harmonisation'. British Journal of Psychiatry 2009, 195(5):379-81Jablensky A. A meta-commentary on the proposal for a meta-structure for DSM-V and ICD-11. Psychological Medicine 2009, 39(12): 2099-2103 (comment/reply)Midford R, Young DJ, Chikritzhs T, Playford D, Kite E, Pascal R (2009). The Effect of Alcohol Sales and Advertising Restrictions on a Remote Australian Community. Drugs: Education, Prevention & Policy. (2009) 1-21, ifirst.Morgan VA and Jablensky AV. Invited author’s reply. Re: Dual Diagnosis Quandries. Letter. British Journal of Psychiatry 2009, 194(5), 469-470. Swanson PB, Kane RT, Pearsall-Jones JG, Swanson CF, Croft ML. How couples cope with the death of a twin or higher order multiple. Twin Research and Human Genetics, 2009, Vol 12(4): 392-402.Waterreus A. D E Laugharne JDE. Screening for the metabolic syndrome in patients receiving antipsychotic treatment: a proposed algorithm. Medical Journal of Australia, 2009, 190(4), 185-189. Young DJ, Levy F, Martin NC, Hay DA. Attention deficit hyperactivity disorder: a Rasch analysis of the SWAN Rating Scale. Child Psychiatry Hum Dev. 2009 Dec, 40(4), 543-59. Epub 2009 May 20.

Books and ChaptersJablensky A. Course and outcome of schizophrenia and their prediction. In M Gelder, N Andreasen, JJ López-Ibor (ed) The New Oxford Textbook of Psychiatry, 2nd edition. Oxford University Press, 2009Jablensky A. Epidemiology of schizophrenia. In M Gelder, N Andreasen, JJ López-Ibor (ed) The New Oxford Textbook of Psychiatry, 2nd edition. Oxford University Press, 2009


Jablensky A. Worldwide burden of schizophrenia. In BJ Sadock, VA Sadock, P Ruiz (ed) Kaplan and Sadock’s Comprehensive Textbook of Psychiatry. Wolters Kluwer / Lippincott Williams & Wilkins, 2009Morgan VA, McGrath J, Hultman C, Zubrick S, Bower C, Croft M, Valuri G, Jablensky AV. The Offspring of Women with Severe Mental Disorder. In Newnham JP, Ross MG (eds). Early Life Origins of Human Health and Disease. Basel. Karger, 2009

Published abstractsJablensky, AV. The future of high risk research. Schizophrenia Bulletin 2009. 35 Suppl. 1: 73-74Morgan VA, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky, A. Environmental and familial determinants of adverse neuropsychiatric outcomes in high risk children of mothers with schizophrenia and other psychoses. Schizophrenia Bulletin 2009, 35 Suppl. 1: 76

2008Journal ArticlesAbel K, Webb R and Morgan V. Taking the Spotlight off Schizophrenia. eLetter. British Journal of Psychiatry http://bjp.rcpsych.org/cgi/eletters/193/4/311 (10 Dec 2008) [IF 2007: 5.446]Jablensky, A.V. and Sartorius, N. What did the WHO Studies really find? Schizophrenia Bulletin, 2008 34(2):253-5. [IF 2007: 5843]Hauck, Y., Rock, D.J.T., Jackiewicz, T. and Jablensky, A.V. Healthy babies for mothers with serious mental illness: a case management framework for mental health clinicians. International Journal of Mental Health Nursing, 17(6), 383-391.[Not in Thomson ISI]Morgan V, Leonard H, Bourke J, Jablensky A. Intellectual disability co-occurring with schizophrenia and other psychiatric illness: a population-based study. British Journal of Psychiatry, 2008 193, 364–372 [IF 2007: 5.446]Morgan F, Morgan V, Clare J, Valuri G, Woodman R, Ferrante A, Castle D, Jablensky A. Schizophrenia and offending: area of residence and the impact of social disorganisation and urbanicity. Trends and Issues in Crime and Criminal Justice 2008, 365. [Not in Thomson ISI]Morgan V, Castle D, Jablensky A. Do women express and experience psychosis differently from men? Epidemiological evidence from the Australian National Study of Low Prevalence (Psychotic) Disorders. Australian and New Zealand Journal of Psychiatry, 2008, 42, 74-82 [IF 2007: 2.573]Davis SR, Shah SM, McKenzie DP, Kulkarni J, Davison SL, Bell RJ. Dehydroepiandrosterone sulfate levels are associated with more favourable cognitive function in women. Journal of Clinical Endocrinology & Metabolism, 2008: 93: 801-808 [IF 2007: 5.493]Swanson PB, Kane RT, Pearsall-Jones JG, Swanson CF, Croft ML. How couples cope with the death of a twin or higher order multiple. Twin Research and Human Genetics (accepted July 2008) [IF 2007: 1.525]

Books and ChaptersFarmer, A.E. and Jablensky, A.V. Current approaches to classification. In R Murray, P Hill, P McGuffin (ed) The Essentials of Postgraduate Psychiatry, 4th ed, Cambridge University PressCastle D and Morgan V. Epidemiology of schizophrenia. in Mueser, K and Jeste, D (eds.) The Clinical Handbook of


Schizophrenia, Guilford Press, New York (2008)

ReportsHauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Clinicians’ Manual. North Metropolitan Area Health Service (Mental Health), WA Department of HealthHauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Framework Overview. North Metropolitan Area Health Service (Mental Health), WA Department of Health.

Published abstracts

Croft ML, Griffith J, Morgan V, Valuri G, Jablensky AV. High risk children of women with schizophrenia and other mental illness: instruments for assessing risks and identifying outcomes. Schizophrenia Research 2008. 102, Issues 1-3, Supp 2: 164Croft ML, Morgan V, Valuri G, Bower J, Zubrick S, Jablensky A. Obstetric risk factors for schizophrenia: identifying neurological damage and/or hypoxia in infants using population databases. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 2.Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky A. Why is the risk of intellectual disability elevated in the children of mothers with schizophrenia and other psychoses? Schizophrenia Research 2008, 102 Suppl 2, 167Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky A. What impact do obstetric complications have on the risk of adverse psychiatric outcomes for the high risk children of mothers with schizophrenia and other psychoses? Schizophrenia Research 2008, 102 Suppl 2, 167-168Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky A Determinants of elevated risk of intellectual disability in children of mothers with psychoses. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 3, A49Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky A Determinants of adverse psychiatric outcomes for high risk children of mothers with schizophrenia and other psychoses: The role of environmental and familial risk factors. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 2, A24


Valuri GM, Croft ML, Morgan VA, Jablensky A. The high risk children of mothers with schizophrenia and other severe mental illness: modelling risk from conception to disease. Schizophrenia Research , 2008, 102, Suppl. 2, 169

2007Journal ArticlesJablensky, A. Does psychiatry need an overarching concept of “mental disorder”? World Psychiatry, 2007, 6, 157-158Jablensky, A. Living in a Kraepelinian world: Kraepelin’s impact on modern psychiatry. History of Psychiatry, 2007, 18, 381-388Jablensky, A. and Morgan, V. Book review: Psychiatric Epidemiology. Searching for the causes of mental disorders, Psychological Medicine, 2007, 37, 905-908Tait RJ. Hulse GK. Waterreus A. Flicker L. Lautenschlager NT. Jamrozik K. Almeida OP. Effectiveness of a smoking cessation intervention in older adults. Addiction. 2007, 102, 148

Books and ChaptersJablensky A. Schizophrenia and related psychoses. In D. Bhugra, K. Bhui (eds) Textbook of Cultural Psychiatry. Cambridge University Press, 2007, 207-223Mendelson G, Jablensky A. What does psychiatry encompass? In S Bloch, B Singh (eds) Foundations of Clinical Psychiatry, 3rd edition, Melbourne University Press, 2007, 69-90


2006Journal ArticlesAlmeida OP. Waterreus A. Hankey GJ. Preventing depression after stroke: Results from a randomized placebo-controlled trial. Journal of Clinical Psychiatry. 2006, 67, 1104-9Castle, D.J., Jablensky, A., McGrath, J.J., Carr, V., Morgan, V., Waterreus, A., Valuri, G., Stain, H., McGuffin, P. and Farmer, A. The diagnostic interview for psychoses (DIP): development, reliability and applications, Psychological Medicine, 2006, 36, 69-80Davis SR, Goldstat R, Papalia M, Shah S, Kulkarni J, Donath S, Bell RJ. Effects of aromatase inhibin on sexual function and wellbeing in postmenopausal women treated with testosterone: a randomized placebo controlled trial. Menopause, 2006 13(1) 37-45Jablensky, A. Historical dictionary of psychiatry, Psychological Medicine, 2006, 36, 277-278Jablensky A. The epidemiology of schizophrenia, ed by RM Murray, P. Jones, E. Susser, J van Os, M Cannon (book review). Australian and New Zealand Journal of Psychiatry, 2006, 40, 503Morgan, V., Korten, A. and Jablensky, A. Modifiable risk factors for hospitalization among people with psychosis: evidence from the National Study of Low Prevalence (Psychotic) Disorders, Australian and New Zealand Journal of Psychiatry, 2006, 40, 683-690Morgan, V.A. and Jablensky, A.V. Exploring the role of reproductive pathology in the etiology of schizophrenia: What happens when mothers with schizophrenia give birth?, Directions in Psychiatry, 2006, 26, 1-15Shah, S, Bell, RJ, Davis SR. Homocysteine and cognitive decline after menopause. Climacteric, 2006 9 (2) 77-87Shah S. Bell RJ, Savage G, Ades R, Papalia M-A, Kulkarni J, Donath S, Davis S. Testosterone aromatization and cognition in women: a randomized placebo controlled trial. Menopause, 2006 13 (4) 600-608

2005Journal ArticlesJablensky, A. Categories, dimensions and prototypes: Critical issues for psychiatric classification, Psychopathology, 2005, 38, 201-205Jablensky, A. The long and winding road of schizophrenia research, Epidemiologia E Psichiatria Sociale, 2005, 14, 179-183Jablensky, A. Boundaries of mental disorders, Current Opinion in Psychiatry, 2005, 18, 653-658Jablensky, A.V., Morgan, V., Zubrick, S.R., Bower, C. and Yellachich, L.A. Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders, American Journal of Psychiatry, 2005, 162, 79-91Kaiser, R., Lohrer, F., Morgan, V. and Hambrecht, M. Changes in the pattern of substance abuse after the onset of psychosis, Australian and New Zealand Journal of Psychiatry, 2005, 39, 467-472Morgan, V.A., Mitchell, P.B. and Jablensky, A.V. The epidemiology of bipolar disorder: sociodemographic, disability and service utilization data from the Australian National Study of Low Prevalence (Psychotic) Disorders, Bipolar Disorders, 2005, 7, 326-337Rossi, A., Morgan, V., Amaddeo, F., Sandri, M., Tansella, M. and Jablensky, A. Psychiatric out-patients seen once only in South Verona and Western Australia: a comparative case-register study, Australian and New Zealand Journal of Psychiatry, 2005, 39, 414-422Valuri G, Stevenson M, Finch C, Hammer B, Elliot B. The Validity of a Four Week Self-Recall of Sports Injuries. Injury Prevention. 2005, 11, 135-137

Books and ChaptersCastle, D.J. and Jablensky, A.V. Diagnosis and classification in psychiatry, Core Psychiatry, ed Wright, P, Stern, J & Phelan, M., Edinburgh, Elsevier Saunders, 2005, 507-515Jablensky, A. Disease and health in the cultural context, Understanding the Global Dimensions of Health, ed Gunn, S.W.A., Mansourian, P.B., Davies, A.M., Piel, A., Sayers, B.McA., New York, Springer Science & Business Media Inc., 2005, 231-239

ReportsFerrante AM, Loh NSN, Maller MG, Valuri GM, Fernandez JA. Crime and Justice Statistics for Western Australia: 2004. Statistical Report.


Crime Research Centre, University of Western Australia, Dec 2005

2004Journal ArticlesAlmeida OP. Waterreus A. Spry N. Flicker L. Martins RN. One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. Psychoneuroendocrinology. 2004, 29, 1071-81.Blagg H & Valuri G. Aboriginal Community Patrols in Australia: Self-Policing, Self Determination and Security. Policing & Society 2004, 14, 313-328.Blagg H & Valuri G. Self-policing and community safety: the work of Aboriginal Community Patrols in Australia. Current Issues in Criminal Justice 2004, 15, 205-219Glasson, E.J., Bower, C., Petterson, B., de Klerk, N., Chaney, G. and Hallmayer, J.F. Perinatal factors and the development of autism: a population study, Archives of General Psychiatry, 2004, 61, 618-627Hansen J, Alessandri, PT, Croft ML, Burton, PR, de Klerk NH. The Western Australian Register of childhood multiples: Effects of questionnaire design and follow-up protocols on response rates and representativeness. Twin Research 2004, 7, 149-161Jablensky A. Researching psychiatry in Western Australia. Australian and New Zealand Journal of Psychiatry 2004, 38, 306-315Jablensky A. The syndrome – an antidote to spurious comorbidity? World Psychiatry 2004, 3, 24-25Kavanagh, D.J., Waghorn, G., Jenner, L., Chant, D.C., Carr, V., Evans, M., Herrman, H., Jablensky, A. and McGrath, J.J. Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample, Schizophrenia Research, 2004, 66, 115-124

ReportsCroft M and Ferrante A. A Review of the Data Matching Processes of the Cervical Cytology Registry for the Western Australian Cervical Cancer Prevention Program. Commissioned by the Women’s Cancer Prevention Program of the WA Department of Health 2004Fernandez JA, Ferrante AM, Loh NSN, Maller MG, Valuri GM. Crime and Justice Statistics for Western Australia: 2003. Statistical Report. Crime Research Centre, University of Western Australia, Dec 2004Leonard H, Petterson B, Bourke J, Morgan V, Glasson E, Bower C. Inaugural report of the idEA database - Intellectual disability in


Western Australia. Perth Western Australia, Institute for Child Health Research, 2004

2003Journal ArticlesJablensky, A.V. and Kalaydjieva, L.V. Genetic epidemiology of schizophrenia: phenotypes, risk factors, and reproductive behaviour, American Journal of Psychiatry, 2003, 160, 425-429 Kendell, R.V. and Jablensky, A. Distinguishing between the validity and utility of psychiatric diagnoses, American Journal of Psychiatry, 2003, 160, 4-12 Lawrence, D.M., Holman, C.D.J., Jablensky, A.V. and Hobbs, M.S.T. Death rate from ischaemic heart disease in Western Australian psychiatric patients 1980-1998, British Journal of Psychiatry, 2003, 182, 31-36 Morgan, V., Janca, A. and Jablensky, A. Psychotic disorders in Australia: patients respond to national survey results, European Psychiatry, 2003, 18, 142 Morgan, V. Two-phase sampling designs for rare outcomes, Australasian Epidemiologist, 2003, 10, 2-3

Books and ChaptersJablensky, A. The epidemiological horizon, Schizophrenia, ed Hirsch, S.R., Weinberger, D.R., England, Blackwell Publishing, 2003, 203-231 Jablensky, A. Diagnosing schizophrenia: a personal view, Schizophrenia, ed Maj, M., Sartorius, N., England, John Wiley & Sons Ltd, 2003, 58-61

ReportsBlagg H, Valuri G. An Overview of Night Patrol Services in Australia. Attorney-General’s Department, Crime Prevention Unit. Mar 2003.


2002Journal ArticlesCastle D, Morgan V, Jablensky A. Antipsychotic use in Australia: the patients’ perspective. Australian and New Zealand Journal of Psychiatry 2002, 36, 633-641Castle D, Morgan V. Attitudes to depot antipsychotics. Letter. British Journal of Psychiatry 2002, 180, 187-188Croft ML, Read AW, de Klerk N, Hansen J, Kurinczuk JJ. Population based ascertainment of twins and their siblings, born in Western Australia 1980 to 1992, through the construction and validation of a maternally linked data base of siblings. Twin Research 2002, 5, 317-23Dunn JC. Almeida OP. Barclay L. Waterreus A. Flicker L. Latent semantic analysis: a new method to measure prose recall. Journal of Clinical & Experimental Neuropsychology. 2002, 24, 26-35Gureje O, Herrman H, Harvey C, Morgan V, Jablensky A. The Australian National Survey of Psychotic Disorders: profile of psychosocial disability and its risk factors. Psychological Medicine 2002, 32, 639-647Jablensky A. Research methods in psychiatric epidemiology: an overview. Australian and New Zealand Journal of Psychiatry 2002, 36, 297-310Jablensky A. The classification of personality disorders: Critical review and need for rethinking. Psychopathology 2002, 35, 112-116Morgan V. Psychiatric Epidemiology. Guest editorial. Australasian Epidemiologist 2002, 9 (2), 1-2Morgan V. What can record linkage contribute to psychiatric epidemiology? Australasian Epidemiologist 2002, 9 (2), 25-29Morgan V, Janca A, Jablensky A. National study of psychotic disorders in Australia: Feedback from individuals with psychosis. The Hong Kong Journal of Psychiatry 2002, 12, 8-12.

Books and ChaptersJablensky, A., & Kendell, R. E. Criteria for assessing a classification in psychiatry. In M. Maj (Ed.), The Future of Psychiatric Diagnosis and Classification. World Psychiatric Association. 2002Jablensky, A., & Cooper, J. E. Classification of dementia and other organic conditions in ICD-10. In J. R. M. Copeland, M. T. Abou-Saleh, & D. G. Blazer (Eds.), Principles and Practice of Geriatric Psychiatry (Vol. 2nd

edition). Chichester: Wiley, 2002


ReportsMorgan V, Castle D, Jablensky A. The use of psychopharmacological and other treatments by persons with psychosis: Self-reported data from the National Study of Low Prevalence (Psychotic) Disorders. Bulletin 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Ageing, 2002Valuri G, Indermaur D, Ferrante A. The Criminal Careers of Drug Offenders in Western Australia: A study of the recidivism and criminal history of those arrested for a drug offence in Western Australia between 1989 and 1999. Report by the Crime Research Centre, University of Western Australia, May 2002.

2001Journal ArticlesAlmeida OP. Waterreus A. Spry N. Corica T. Martins G. Martins RN. Flicker L. Effect of testosterone deprivation on the cognitive performance of a patient with Alzheimer's disease. International Journal of Geriatric Psychiatry. 2001, 16, 822-825Morgan V, Jablensky A, Castle DJ . Season of birth in schizophrenia and affective psychoses in Western Australia 1916-1961. Acta Psychiatrica Scandinavica, 2001, 104, 138-147Jablensky A. Classification of nonschizophrenic psychotic disorders: A historical perspective. Current Psychiatry Reports 2001, 3, 326-331Gandy S. Almeida OP. Fonte J. Lim D. Waterreus A. Spry N. Flicker L. Martins RN. Chemical andropause and amyloid-beta Journal of the American Medical Association. 2001, 285, 2195-2196Gureje O, Herrman H, Harvey C, Trauer T, Jablensky A. Defining disability in psychosis: performance of the diagnostic interview for psychosis – disability module (DIP-DIS) in the Australian National Survey of Psychotic Disorders. Australian and New Zealand Journal of Psychiatry 2001, 35, 846-851Jablensky A, Lawrence D. Schizophrenia and cancer: Is there a need to invoke a protective gene? Archives of General Psychiatry 2001, 58, 579-580.

Books and ChaptersJablensky, A., Johnson, R., Bunney, W., et al. Neurological, Psychiatric, and Developmental Disorders; Meeting the Challenge in the Developing World. Washington DC: National Academy Press, 2001Jablensky A. Symptoms of schizophrenia. In Henn F., Sartorius N., Helmchen H., Lauter H. (eds) Contemporary Psychiatry, vol 3. Springer, Berlin, 2001, 3-36.Jablensky A. Schizophrenia. In: Neurological, Psychiatric, and Developmental Disorders. Meeting the Challenge in the Developing World. Institute of Medicine, National Academy of Science, Washington DC, 2001Mendelson, G., & Jablensky, A. What does psychiatry encompass? In S. Bloch & B. Singh (Eds.), Foundations of Clinical Psychiatry (2nd ed). Melbourne: Melbourne University Press, 2001, 63-81


ReportsMorgan, V., Korten, A., Valuri, G., Waterreus, A. and Jablensky, A on behalf of the Low Prevalence Disorders Study Group. National Survey of Mental Health and Wellbeing. People Living with Psychotic Illness: An Australian Study 1997-98. Confidentialised Unit Record File. Technical paper. September 2001Valuri G, Morgan V, Jablensky A. Deriving a Research Diagnosis from a Mental Health Register. Report to Western Australian Department of Health. Perth: University of Western Australia Department of Psychiatry and Behavioural Science; 7 March 2001.

2000Journal ArticlesHansen J, de Klerk N, Croft ML, Alessandri P, Burton P. The Western Australian Twin Child Health (WATCH) Study: work in progress. Australasian Epidemiologist 2000, 7, 2Jablensky A. The concept of schizophrenia: pro et contra. Epidemiologia e Psichiatria Sociale 2000, 8, 242-247Jablensky A., McGrath J., Herrman H., Castle D., Gureje O., Evans M, Carr V., Morgan V., Korten A., Harvey C. Psychotic disorders in urban areas: an overview of the Study on Low Prevalence Disorders. Australian and New Zealand Journal of Psychiatry 2000, 34, 221-236Jablensky A. Prevalence and incidence of schizophrenia spectrum disorders: implications for prevention. Australian and New Zealand Journal of Psychiatry 2000, 34, Suppl S26-S34Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. European Archives of Psychiatry and Clinical Neuroscience 2000, 250, 274-85Lawrence D, Holman CD, Jablensky A, Threlfall TJ, Fuller SA Excess cancer mortality in Western Australian psychiatric patients due to higher case fatality rates. Acta Psychiatrica Scandinavica 2000, 101, 382-388Lawrence D, Almeida O, Hulse G, Jablensky A Suicide and attempted suicide among older adults in Western Australia. Psychological Medicine 2000, 30, 813-821Morgan V, Janca A. Revisiting the journal impact factor. Australasian Psychiatry 2000, 8, 230-235

Books and ChaptersJablensky A Epidemiology of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 585-599.Jablensky A Course and prognosis of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 612-621.


1999Journal ArticlesBlanchard MR. Waterreus A. Mann AH. Can a brief intervention have a longer-term benefit? The case of the research nurse and depressed older people in the community. International Journal of Geriatric Psychiatry. 1999, 14(9):733-8Finch C, Valuri G, Ozanne-Smith J. Injury Surveillance During Medical Coverage of Sporting Events – Development and Testing of a Standardised Data Collection Form. Journal of Science and Medicine in Sport 1999, 2, 42-56Jablensky A. Schizophrenia: epidemiology. Current Opinion in Psychiatry 1999, 12, 19-28Jablensky A. The conflict of the nosologists: views on schizophrenia and manic depressive illness in the early part of the 20th century. Schizophrenia Research 1999, 39, 95-100Jablensky A. The Forest and the Trees. Personal History & Health. The Midtown Longitudinal Study 1954-1974, by Leo Srole and Ernest Joel Millman (book review). Contemporary Psychology / APA Review of Books 1999, 45, 221-223Jablensky A. The nature of psychiatric classification: issues beyond ICD-10 and DSM-IV. Australian and New Zealand Journal of Psychiatry 1999, 33, 137-144Lawrence D.M., Holman D.J, Jablensky A., Fuller S.A. Suicide rates in psychiatric in-patients: an application of record linkage to mental health research. Australian and New Zealand Journal of Public Health 1999, 23, 468-470Jablensky A Psychiatric epidemiology and the global public health agenda. International Journal of Mental Health 1999, 28, 6-14

Books and ChaptersJablensky A. The concept of somatoform disorders: A comment on the mind-body problem in psychiatry. In: Ono Y et al (Eds) Somatoform Disorders: A Worldwide Perspective. Springer, Tokyo, 1999, 3-10Jablensky A Beyond ICD-10 and DSM-IV: issues in contemporary psychiatry. In Promoting Mental Health Internationally. Ed by de Girolamo G., Eisenberg L. and Goldberg D.P. Gaskell, London, 1999, 47-56Jablensky A Diagnosing schizophrenia – a personal view. In Maj M. (ed) Evidence and Experience in Psychiatry, vol. 2, World Psychiatric Association, 1999Jablensky A. The 100-year epidemiology of schizophrenia. In Search for the Causes of Schizophrenia, Vol. IV, ed by W.F. Gattaz and

H. Häfner. Steinkopff, Darmstadt, 1999, 3-19


ReportsCroft M. Creation of a Patient Master Index for Tasmania’s Mental Health Services. Commissioned by Tasmania’s Department of Health and Human Services 1999Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98 - An Overview. National Survey of Mental Health and Wellbeing: Bulletin 1. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98. National Survey of Mental Health and Wellbeing: Report 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.

1998Journal ArticlesFinch C, Valuri G, Ozanne-Smith J. Sports and Active Recreation Injuries in Australia - Evidence from Emergency Department Presentations. British Journal of Sports Medicine. 1998, 32, 220-225

ReportsSomerford P, Pinder T, Valuri G, Price S, Stevens M. Bicyle Injury Hospitalisations and Deaths in Western Australia 1981 – 1995. Injury Control Program - Disease Control, Health Department of Western Australia, July 1998Croft M. Record linkage of the NSW Registrar General’s registrations of deaths to the NSW Inpatient statistics collection records for 1995/96 coronary artery bypass graft patients. Commissioned by NSW Health Department 1998


1997Journal ArticlesJablensky A. The 100-year epidemiology of schizophrenia. Schizophrenia Research 1997, 28, 111-125Jablensky A. Organic origins of psychoses. Brain Pathology 1997, 7, 1043-1046Jablensky A., Cole S.W. Is the earlier age at onset of schizophrenia in males a confounded finding? British Journal of Psychiatry 1996, 170, 234-240Morgan V, Castle D, Page A, Fazio S, Gurrin L, Burton P, Montgomery P, Jablensky A. Influenza epidemics and the incidence of schizophrenia, affective disorders and mental retardation in Western Australia: no evidence of a major effect. Schizophrenia Research 1997, 26, 25-39Stanley FJ, Read AW, Kurinczuk JJ, Croft ML, Bower C. A population maternal and child health research data base for research and policy evaluation in Western Australia. Seminars in neonatology 1997, 2,195-201

Published conference proceedingsValuri, G. Finch, C., Ozanne-Smith, J. A Standardised Data Collection Methodology for Sports Injury Surveillance. Computerised Data Entry and Analysis System. In: McGuiness B, Leeder T (eds). Making It Happen. Proceedings of the Fourth National Health Informatics Conference. Melbourne, Australia 19th - 21st August 1996, 45- 49

Books and ChaptersJablensky A. International perspective in transcultural mental health. In: Ferguson B., Barnes D. (eds) Perspectives on Transcultural Mental Health. Transcultural Mental Health Centre, Sydney, 1997, 1-12

ReportsCroft M, Ferrante A. The corporate data warehouse project data matching project. Commissioned by WA Ministry of Justice 1997Croft M. A description of the availability, accessibility and utility of the major health data bases relevant to research into the incidence, prevalence, management and health outcomes of diabetes in Western Australia . Commissioned by Diabetes Australia (WA) 1997Croft M. A Proposal to establish a diabetes registry in Western Australia using record linkage. Commissioned by Diabetes Australia (WA) 1997Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe

Valley. Monash University Accident Research Centre Report No. 113, May 1997


Waterreus A. Mann A. Blanchard M. Aquilina C. Out of the darkness; a training package in the recognition and management of depression in older people for primary health care workers. 1997. Institute of Psychiatry, London, England.

1996Journal ArticlesJablensky A. (1996) Books reconsidered: General Psychopathology by Karl Jaspers. Australian & New Zealand Journal of Psychiatry 1996, 30, 885-888Morgan V, Castle D, Jablensky A. Seasonality of birth in Western Australia. Letter. British Journal of Psychiatry 1996, 168, 521

Books and ChaptersJablensky A. (1996) Diagnosis and classification in a developing country. In: Tantam D., Appleby L. and Duncan A. (eds) Psychiatry for the Developing World. Gaskell, London, 1996, 27-47

ReportsCroft M. A feasibility study of the probabilistic record linkage of the NSW Road Traffic Authority’s Road Traffic Accident data base to the NSW Inpatient statistics collection records for 1993/94. Commissioned by NSW Health Department 1996Finch, C., Valuri G., McGrath, A. Pitching Injury Prevention to Baseballers and Softballers: A Review of the Literature. Monash University Accident Research Centre Report No. 106, Dec 1996


1995Journal ArticlesBlanchard, M. R; Waterreus, A; Mann, A. H. The effect of primary care nurse intervention upon older people screened as depressed. International Journal of Geriatric Psychiatry. 1995, 10, 289-298.Jablensky A. Schizophrenia: recent epidemiological issues. Epidemiologic Reviews 1995, 17, 10-20Jablensky A. Comments on "Prenatal exposure to influenza epidemics and risk of mental retardation" by Takei N. et al. European Archive of Psychiatry and Clinical Neuroscience 1995, 245, 262-263Jablensky A. Kraepelin's legacy: paradigm or pitfall for modern psychiatry? European Archive of Psychiatry and Clinical Neuroscienc, 1995, 245, 186-188Jablensky A. Diagnosis and classification in a developing country. Malaysian Journal of Psychiatry 1995, 3, 1-8

Books and ChaptersJablensky A. Future perspectives on concepts of disease. In: WHO-CIOMS, The Impact of Scientific Advances on Future Health, World Health Organization, Geneva, 65-73.

Jablensky A. Schizophrenia: the epidemiological horizon. In: Hirsch S.R. and Weinberger D. (eds) Schizophrenia. Blackwell, London , 206-252.Jablensky A., Eaton W.W. Schizophrenia. In: Jablensky A. [ed] Epidemiological Psychiatry. Bailliere Tindall, London, 283-306.

ReportsCroft M. Report on the linkage of the NSW Neonatal Intensive Care Unit Study data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995Croft M. Report on the linkage of the NSW Neonatal Emergency Transport Service data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe Valley. Draft Report on the First Six Months. Monash University Accident Research Centre Report. Sept 1995.Valuri, G. Hazard 22 Product Related Injuries - A Selection, Domestic Architectural Glass Injuries, Victorian Injury Surveillance System. 1995, March, 2-5


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