Double Nicking by RN

Errata

A-GuidedCRISPR Cas9 for EnhancedGenome Editing SpecificityF. Ann Ran, Patrick D. Hsu, Chie-Yu Lin, Jonathan S. Gootenberg, Silvana Konermann, Alexandro E. Trevino,David A. Scott, Azusa Inoue, Shogo Matoba, Yi Zhang, and Feng Zhang**Correspondence: zhang@broadinstitute.org

http://dx.doi.org/10.1016/j.cell.2013.09.040

(Cell 154, 1380–1389; August 29, 2013)

We wish to correct errors introduced during the preparation of two figures and two supplemental tables in the above article. In the

‘‘DYRK1A’’ plot of Figure 2B, we inadvertently omitted seven additional data points that were presented in Table S1. In Figure 4B, the

labels for two panels were inadvertently switched. Tables S1 and S2, which report the sequences of sgRNAs, contained several

typographical errors. None of these errors affect any of the results presented or their interpretations. Corrected figures appear

below and with the article online. Tables S1 and S2 have also been updated online. We regret these errors and apologize for

the inconvenience that they may have caused.

A

B

C

Figure 2. Double Nicking Facilitates Effi-

cient Genome Editing in Human Cells

Cell 155, 478–480, October 10, 2013 ª2013 Elsevier Inc. 479

A

B C

D

Figure 4. Double Nicking Allows Insertion

into the Genome via HDR in Human Cells

480 Cell 155, 478–480, October 10, 2013 ª2013 Elsevier Inc.