Cornea Transparency

J.I. Clark Fourier and power law analysis of structural complexity in cornea and lens Micron 32: 239-249 (2001).

Articular Cartilage: Current Imaging TechnologyArticular Cartilage: Current Imaging Technology

Radiographic Grading SystemsRadiographic Grading Systems

Visual Inspection Grading SystemsVisual Inspection Grading Systems

Histologic Grading SystemsHistologic Grading Systems

http://faculty.uca.edu/~johnc/proteoglycan.jpg

Proteoglycans

Middle Zone

Deep Zone

Calcified Cartilage500 µm

50 µm

Superficial ZoneA B

C

Articular Cartilage

350 400 450 500 550 600

wavelength (nm)

0

inte

nsit

y (a

.u.)

SHG

TPF

A

SHG

B

TPF

C

Optical imaging of articular cartilage

TPF

SHG

Hist

500 µm

6 µm

Hyaline matrix

Strain profile of articular cartilage

R.M. Schinagl, M.K. Ting, J.H. Price, R.L. Sah Annals of Biomedical Engineering 24: 500-512 (1996).

20 m

30 m

45 m

A(SHG + TPF)

B(TPF)

C(SHG)

Superficial Zone

Middle Zone

Middle Zone

20 m

8 µm

A

B

C

(SHG + TPF) SHG

40 µm 8 µm

SHG