corinne keet 6/13/2018 demographic and personal … · 1. hamrick se, gremmels db, keet ca, leonard...

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CURRICULUM VITAE Corinne Keet 6/13/2018 DEMOGRAPHIC AND PERSONAL INFORMATION Current Appointments Associate Professor of Pediatrics Department of Pediatrics Johns Hopkins School of Medicine Personal Data Business Address: Johns Hopkins Hospital 600 N. Wolfe St. CMSC 1102 Baltimore, MD 21287 Tel: 410-955-5883 Cell: 410-209-0747 Fax: 410-955-0229 Email: [email protected] Education and Training (in chronological order): Year Degree/Certificate Institution Discipline Undergraduate 1998 B.A. University of California, Berkeley, Chemistry Graduate 2001 M.S. University of California, Berkeley, Health Sciences 2004 M.D. University of California, San Francisco 2014 PhD Johns Hopkins Bloomberg School of Public Health, Epidemiology Post-doctoral 2004 - 5 Internship in Pediatrics Johns Hopkins Hospital 2005 -7 Residency in Pediatrics Johns Hopkins Hospital 2007 - 10 Fellowship Allergy/Immunology Johns Hopkins University Professional Experience Dates Positions Institutions 2010-2015 Assistant Professor Johns Hopkins School of Medicine, Baltimore, Maryland 2016- Co-Director of the Pediatric Clinical Research Unit Johns Hopkins School of Medicine, Baltimore, Maryland 2016- Associate Professor Johns Hopkins School of Medicine, Baltimore, Maryland RESEARCH ACTIVITIES Publications: Peer-reviewed Original Science Research

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Page 1: Corinne Keet 6/13/2018 DEMOGRAPHIC AND PERSONAL … · 1. Hamrick SE, Gremmels DB, Keet CA, Leonard CH, Connell JK, Hawgood S, Piecuch RE. Neurodevelopmental outcome of infants supported

CURRICULUM VITAE

Corinne Keet 6/13/2018

DEMOGRAPHIC AND PERSONAL INFORMATION

Current Appointments

Associate Professor of Pediatrics

Department of Pediatrics

Johns Hopkins School of Medicine

Personal Data

Business Address: Johns Hopkins Hospital

600 N. Wolfe St. CMSC 1102

Baltimore, MD 21287

Tel: 410-955-5883

Cell: 410-209-0747

Fax: 410-955-0229

Email: [email protected]

Education and Training (in chronological order):

Year Degree/Certificate Institution Discipline

Undergraduate 1998 B.A. University of California, Berkeley, Chemistry

Graduate 2001 M.S. University of California, Berkeley, Health Sciences

2004 M.D. University of California, San Francisco

2014 PhD Johns Hopkins Bloomberg School of Public Health,

Epidemiology

Post-doctoral 2004 - 5 Internship in Pediatrics Johns Hopkins Hospital

2005 -7 Residency in Pediatrics Johns Hopkins Hospital

2007 - 10 Fellowship Allergy/Immunology Johns Hopkins

University

Professional Experience

Dates Positions Institutions

2010-2015 Assistant Professor Johns Hopkins School of Medicine,

Baltimore, Maryland

2016- Co-Director of the Pediatric Clinical Research Unit

Johns Hopkins School of Medicine,

Baltimore, Maryland

2016- Associate Professor Johns Hopkins School of Medicine,

Baltimore, Maryland

RESEARCH ACTIVITIES

Publications: Peer-reviewed Original Science Research

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1. Hamrick SE, Gremmels DB, Keet CA, Leonard CH, Connell JK, Hawgood S,

Piecuch RE. Neurodevelopmental outcome of infants supported with

extracorporeal membrane oxygenation after cardiac surgery. Pediatrics. 2003; 11:

e671-5.

2. Keet CA, Matsui EC, Dhillon G, Lenehan P, Paterakis M, Wood RA. The

Natural History of Wheat Allergy. Annals of Allergy Asthma Immunol. 2009;

102: 410-415.

3. Keet CA, McCormack MC, Peng RD, Matsui EC. Age- and Atopy- Dependent

Effects of Age- and Atopy-Dependent Effects of Vitamin D on Wheeze and

Asthma. Journal of Allergy and Clinical Immunology. 2011; 128: 414-16.

4. Neuman-Sunshine DL, Eckman JA, Keet CA, Matsui EC, Peng RD, Lenehan PJ,

Wood RA. “The natural history of persistent peanut allergy”, Annals of Allergy

Asthma Immunol. 2012; 108: 326-331

5. Keet CA, Wood RA, Masui EC. Personal and parental nativity as risk factors for

food sensitization. Journal of Allergy and Clinical Immunology. 2012; 129: 169-

175.

6. Keet CA, Frischmeyer-Guerrerio PA, Thyagarajan A, Schroeder JT, Hamilton

RG, Boden S, Steele P, Driggers S, Burks AW, Wood RA. The Safety and

Efficacy of Sublingual and Oral Immunotherapy for Milk Allergy. Journal of

Allergy and Clinical Immunology. 2012; 129:448-55,455.e1-5.

7. Keet CA, Matsui EC, Savage JH, Neuman-Sunshine D, Skripak J, Peng RD,

Wood, RA. “Potential mechanisms for the association between fall birth and food

allergy”, Allergy. 2012; 67:775-82

8. Savage J, Matsui EC, Wood RA, Keet CA. Urinary levels of triclosan and

parabens are associated with aeroallergen and food sensitization. Journal of

Allergy and Clinical Immunology. 2012; 130: 453-460.e7.

9. Keet CA, Wood RA, Matsui, EC. Limitations of reliance on specific IgE for

epidemiologic surveillance of food allergy. Journal of Allergy and Clinical

Immunology. 2012; 130: 1207-1209

10. Keet CA, Johnson K, Savage JH, Hamilton RG, Wood RA. Evaluation of Ara h2

IgE thresholds in the diagnosis of peanut allergy in a clinical population. JACI: In

Practice. 2013; 1: 101-103

11. Keet CA, Seopaul S, Knorr S, Narisety S, Skripak J, Wood R. Long-Term

Follow-up of Oral Immunotherapy for Cow’s Milk Allergy. Journal of Allergy

and Clinical Immunology, 2013; 132: 737-739.

12. Holbrook T, Keet CA, Guerrerio P, Wood R. Use of Ondansetron in the

Treatment of Food Protein Induced Enterocolitis Syndrome (FPIES) Reactions.

Journal of Allergy and Clinical Immunology 2013; 132: 1219-20.

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13. McGowan E, Keet CA. Prevalence of self-reported food allergy in the National

Health and Nutrition Examination Survey (NHANES) 2007-2010. Journal of

Allergy and Clinical Immunology 2013; 132:1216-1219.e5.

14. Schroeder, JT, Bieneman AP, Chinester KL, Keet, CA; Hamilton, RG;

MacGlashan DW Jr., Wood, R, Guerrerio, P; Spontaneous Basophil Responses in

Food Allergic Children are Transferable by Plasma and are IgE-dependent.

Journal of Allergy and Clinical Immunology.2013; 132:1428-31.

15. Keet CA; Shreffler WG; Peng RD; Matsui W; Matsui EC; Associations between

serum folate and vitamin D levels and incident mouse sensitization in adults.

Journal of Allergy and Clinical Immunology 2014; 133: 399-404.

16. Keet CA; Savage JH; Seopaul S; Peng RD; Wood RA; Matsui EC. Temporal

Trends and Racial/Ethnic Disparity in Self-reported Pediatric Food Allergy in the

US. Annals of Allergy, Asthma and Immunology 2014;112: 222-229.e3.

17. Savage JH; Matsui EC; McCormack M, Wood RA; Keet CA. The association

between asthma and allergic disease and mortality – a 30 year follow-up study”.

Journal of Allergy and Clinical Immunology. 2014; 133: 1484-7.

18. Radano, MC; Yuan Q; Katz A; Fleming JT; Kubala S; Shreffler W; Keet CA;.

Cesarean Section and Antibiotic Use Found to be Associated With Eosinophilic

Esophagitis. JACI in practice. 2014; 2: 475-477

19. Guerrerio, P; Keet, CA; Guerrerio, AL; Chichester, KL; Bieneman, AP;

Hamilton, RG; Wood, RA; Schroeder, JT. Modulation of Dendritic Cell Innate

and Adaptive Immune Function by Oral and Sublingual Immunotherapy. Clinical

Immunology. 2014; 155: 47-59.

20. Robbins, K; Wood, RA; Keet, CA. Milk Allergy is associated with decreased

growth in U.S. children. Journal of Allergy and Clinical Immunology.

2014;134:1466-1468.e6

21. Robbins, KA; Guerrerio, AL; Hauck, S; Henry, B; Keet, CA; Brereton, NH; Oh,

S; Stasinopolos, DM; Wood, RA. Growth and nutrition in children with multiple

food allergies who require elemental formula for nutritional support. Journal of

Allergy and Clinical Immunology. 2014; 134:1463-1466.e5

22. Chen, Q; Martin, R; Hoag, SW; Wood, RA; Mao, HQ; Keet, CA. Formulation

and Characterization of Orally Dissolving Thin Films Containing the German

Cockroach Blatella germanica (Bla g 2) Allergen. International Journal of

Pharma Sciences 2014; 4: 730-735

23. Narisety, S; Frischmeyer-Guerrerio P; Keet, CA, Gorelik M; Schroeder J;

Hamilton RA, Wood RA. A Randomized, Double-Blind, Placebo-Controlled Pilot

Study of Sublingual versus Oral Immunotherapy for the Treatment of Peanut

Allergy. Journal of Allergy and Clinical Immunology. 2015; 135: 1275-82.

24. Gorelik, M, Narisety, S; Guerrerio, AL; Chichester, KL; Keet, CA; Bieneman,

AP; Hamilton, RG; Wood, RA; Schroeder, JT; Frischmeyer-Guerrerio, PA.

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Immunologic Suppression to Peanut During Immunotherapy Is Often Transient.

Journal of Allergy and Clinical Immunology. 2015; 135:1283-92

25. Keet, CA; McCormack, MC; Pollack, CE; Pend, RD; McGowan EC; Matsui EC.

Neighborhood Poverty, Urban Residence, Race/ethnicity and Asthma: Rethinking

the Inner-city Asthma Epidemic. Journal of Allergy and Clinical Immunology.

2015; 135: 655-62

26. Xiumei Hong, X; Hao, K; Ladd-Acosta, C; Hansen, KD; Tsai, HJ; Liu, X; Xu, X;

Thornton, TA; Caruso, D; Keet, CA; Sun, Y; Wang, G; Luo, W; Kumar, R;

Fuleihan, R; Singh, AM; Kim, JS; Story, RE; Gupta, RS; Gao, P; Chen, Z;

Walker, SO; Bartell, TR; Beaty, TH; Fallin, MD; Schleimer, R; Holt, PG;

Nadeau, KC; Wood, RA; Pongracic, JA; Weeks, DA; Wang, X. Genome-wide

Association Study of Food Allergy Identifies Peanut Allergy-Specific

Susceptibility Loci and Evidence of Epigenetic Mediation in U.S. Children of

European Ancestry. Nature Communications. 2015;6: 6304

27. McGowan, EC; McCormack MC; Pollack CE; Peng, RD; Keet, CA; The Effect

of Poverty, Urbanization, and Race/Ethnicity on Perceived Food Allergy in the

United States. Annals of Allergy, Asthma and Immunology. 2015; 115:85-86

28. He, H; Butz, A; Keet, CA; Minkovitz, C; Hong, X; Caruso, D; Pearson, C;

Cohen, R; Wills-Karp, M; Zuckerman, B; Hughes, M.; Wang, X; Preterm Birth

with Childhood Asthma: The Role of Degree of Prematurity and Asthma

Definitions. American Journal of Respiratory and Critical Care Medicine. 2015;

192:20-3

29. Jones, SM; Burks, AW; Keet, CA; Vickery, BP; Scurlock, AM; Wood, RA; Liu,

AH; Sicherer, SH; Henning, AK; Lindblad, RW; Dawson, P; Berin, C; Fleischer,

DM; Leung, DYM; Plaut, M; Sampson, HA. Long-Term Treatment with Egg

Oral Immunotherapy Enhances Sustained Unresponsiveness That Persists After

Cessation of Therapy. Journal of Allergy and Clinical Immunology. 2016;

137:1117-27.

30. Hong, X; Ladd-Acosta, C; Hao, K; Sherwood, B; Ji, H; Keet, CA; Kumar, R;

Caruso, D; Liu, X; Wang, G; Chen, Z; Ji, Y; Mao, G; Walker, SO; Bartell, TR; Ji,

Z; Sun, Y; Tsai, H; Pongracic, JA; Weeks, DE; Wang, X. Epigenome-wide

association study links site-specific DNA methylation changes with cow’s milk

allergy. Journal of Allergy and Clinical Immunology. 2016; 138: 908-911

31. McGowan, EC; Peng, RD; Salo, PM; Zeldin, DC; Keet, CA. Changes in Food-

specific IgE Over Time in the National Health and Nutrition Examination Survey

(NHANES). JACI: In Practice. 2016; 4: 713-20

32. Vickery BP; Berglund JP; Burk CM; Fine JP; Kim EH; Kim JI; Keet CA; Kulis

M; Orgel KG; Guo R; Steele PH; Virkud YV; Ye P; Wright BL; Wood RA;

Burks AW. Early oral immunotherapy in peanut-allergic preschool children is

safe and highly effective. Journal of Allergy and Clinical Immunotherapy. 2017;

139: 173-181

33. McGowan, EC; Matsui, EC; Peng, RD; Salo, PM; Zeldin, DC; Keet, CA.

Racial/ethnic and socioeconomic differences in self-report of food allergy among

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food-sensitized children in NHANES III. Annals of Allergy Asthma Immunol.

2016; 117(5):579-572

34. Hughes, HK; Matsui, EC; Tschudy, MM; Pollack, CE; Keet, CA. Pediatric

Asthma Health Disparities: Race, Hardship, Housing, and Asthma in a National

Survey. Academic Pediatrics. 2017; 17; 127-134

35. Keet, CA; Matsui, EC; McCormack, MC; Peng, RD. Urban residence,

neighborhood poverty, race/ethnicity and asthma morbidity among children in

Medicaid. Journal of Allergy and Clinical Immunotherapy. 2017; 140; 822-827

36. Keet, CA; Keller, J; Peng, RD. Long-term coarse PM exposure is associated with

asthma among children in Medicaid. AJRCCM. 2017 Dec 15. Epub ahead of print

37. Dunlop JH, Keet CA, Mudd K, Wood RA. Long-term Follow-up After Baked

Milk Introduction. JACI: In practice. 2018 Feb 2.

38. Dunlop, JH, Keet CA. Goals and Motivations of Families Pursuing Oral

Immunotherapy for Food Allergy. JACI: In Practice. In press.

Inventions, Patents, Copyrights

Date Title

2016 Patent Application 20150125495: ORALLY

DISSOLVING THIN FILMS CONTAINING

ALLERGENS AND METHODS OF MAKING AND USE

Extramural Funding (current, pending, previous)

Current:

1U01AI125290 (Keet) 7/01/2016-6/30/2021 4.2 calendar

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

$1,934,791 (direct)

Role: PI

Early Peanut Introduction: Translation to Clinical Practice

This proposal is to enroll infants at high risk of peanut allergy in order to

determine the risk of peanut allergy in various high risk groups, how screening

tests for peanut allergy perform in these groups, and to characterize the

relationship between dose of peanut and peanut prevention.

1UM2AI130836-01 (Wood) 03/01/17 - 02/29/24 1.20 calendar

NIH/NIAID $3,673,872 (direct)

Role: Co-Investigator and Project Lead

New Horizons In The Prevention And Treatment Of Food Allergy Fund

Our goals will be 1) to rapidly implement a food allergy registry study that will

provide the means to fully characterize and phenotype a large population of

patients, determine true rates of reactions, and serve as a recruitment source for

clinical trials, 2) to develop and implement a novel, cutting edge protocol for the

treatment of food allergy, 3) to choose and develop additional protocols for

inclusion in the consortium, especially related to other promising approaches in

development for either treatment or prevention, 4) to integrate the Biomarker

Facility into each clinical protocol and 5) to maximally leverage the resources and

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potential of the Opportunity Fund to expand the mechanistic study of food allergy

and its treatment.

1UM1AI130838-01 (Wood) 03/03/17 – 02/29/24 .60 calendar

NIH/NIAID $143,878 (direct)

Role: Co-Investigator

Clinical Research Unit: Johns Hopkins University

Our aims are to maintain and expand a highly trained team capable of conducting

cutting edge food allergy research 2) Organize and facilitate communication

between the Hopkins CRU and each of the consortium’s components, including

the Leadership Center, the NIAID, and the SACCC, 3) Sustain and expand a large

and diverse patient population of food allergic patients, 4) Train new and early

stage investigators in the conduct of clinical investigation in food allergy and 5)

Develop and implement a cutting edge clinical trial on the treatment of food

allergy.

UL1TR001079 (Ford) 09/26/13 – 04/30/18 3.6 calendar

NIH/NCATS $10,632,606

Role: Co-director of the Pediatric Clinical Research Unit

The Johns Hopkins Institute for Clinical and Translational Research

The Johns Hopkins Institute for Clinical and Translational Research (ICTR) is

dedicated to creating a new model for conducting clinical and translational

research throughout the Johns Hopkins University, by addressing critical

obstacles that impede the progress of basic science discoveries to the clinic,

clinical discoveries into the community and results back to the research

community. This is accomplished through the fostering of communities of

translational scientists, providing coordinated expert consultation through a

research studio, pilot grant funding, key clinical and translational infrastructure to

help researchers implement their research, and through the training and career

development of the next generation of translational scientists.

1R01ES026170 (Matsui/Keet) 3/16-2/21 0.96

calendar

NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

$1,646,622 (direct)

Role: Co-PI

The effect of a housing mobility program on environmental exposures and asthma

morbidity among low-income minority children

5R01ES023447-05 (Matsui) 01/13/2014 – 10/31/2018 0.96 calendar NIH/NIEHS $412,174 Environmental Control as Add-on Therapy in Urban Children with Asthma Role: Co-PI

Our aims are to determine the effect of the addition of ECS to controller medication titration on controller medication requirements and allergic inflammatory biomarkers, and to determine whether reductions in particulate matter (PM) and/or indoor allergens mediate the effects of an ECS on asthma.

1 R21 AI133492-01A1 (Davis) 6/18/18-5/31/20

National Institute of Allergy and Infectious Diseases

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Role: Co-I

The effects of a housing mobility program on home environmental and host

airway microbiota and asthma morbidity among low-income minority children.

Previous:

1K23AI103187: (Keet) 08/15/2012-12/1/2016 6-9 calendar

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

$633,050 (direct)

Role: PI

Genetic and Environmental Determinants of Food Allergy

This grant supports the career development of the candidate in a project focused

on the genetic determinants of food allergy.

5KL2RR025006 (Ford) 6/1/10 – 5/31/12 9.6 calendar

Institute for Clinical and Translational Research KL2

NIH/NCRR

Role: KL2 Scholar

This CTSA grant supports clinical and translational research throughout Johns

Hopkins. It includes support for education and training of new translational

investigators, facilities in which clinical research can take place and infrastructure

support of patient recruitment, bioinformatics, biostatistics and translational core

centers.

5P50ES015903-03 (Breysse) 09/29/07-05/31/13 2.2 calendar

NATIONAL INSTITUTES OF HEALTH

Center for Childhood Asthma in the Urban Environment

Role: Co-Investigator

The long-term goals of this Center are to examine how exposures to

environmental pollutants and allergens may relate to airway inflammation and

respiratory morbidity in children with asthma living in the inner city of Baltimore,

and to search for new ways to reduce asthma morbidity by reducing exposure to

these agents.

NIH/T32AI007007 Wood (PI) 7/1/75-8/31/14 12 calendar

Research Training in Pediatric Allergy and Immunology

Project: Comparison of Sublingual and Oral Immunotherapy for Milk Allergy

Role: Post-Doctoral Fellow

The goal of this study was to compare sublingual and oral immunotherapy for

children with severe milk allergy, and to evaluate the immunological correlates of

treatment.

1R21HD: 073557 (Keet) 06/10/2013-05/31/2016 1.2 calendar

EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD

HEALTH & HUMAN DEVELOPMENT

$282,702 (direct)

Role: PI

Development of a Dissolving Film for Allergen Immunotherapy in Children

We have developed a film for use in the treatment of peanut allergy. In this grant,

we propose to extend this method to other important allergens for children and

explore methods to optimize its use in children.

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1R21AI107085 (Keet) 07/13-05/16 1.2 calendar

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

$282,702 (direct)

Role: PI

Temporal Trend in Food Sensitization in U.S. Children

This proposal is to measure specific IgE to selected foods in the NHANES III

survey (1988-1994) in order to compare rates of sensitization with the NHANE

2005-6 survey to determine whether sensitization is increasing in parallel with

self-report of food allergy.

Gerber Family Foundation (Yung) 10/13-10/16 0.2 calendar

$300,000 (direct)

Role: Consultant

Early Risk Factors for Gastrointestinal Mucosal Food Allergies

This proposal is to establish a birth cohort to examine early life risk factors for

food allergy.

EDUCATIONAL ACTIVITIES

Educational Publications

Invited Review Articles

1. Keet CA, Wood RA. Food allergy and anaphylaxis. Immunol Allergy Clin North

Am. 2007; 27:193-212, vi.

2. Keet CA and Wood RA. Risk Factors for Peanut Allergy. Journal of Allergy and

Clinical Immunology. 2009; 124:387

3. Keet C. Recognition and Diagnosis of Food-Related Anaphylaxis. Pediatric Clin

North Am. 2011; 58:377-88.

4. Narisety SD, Keet CA. Sublingual vs. Oral Immunotherapy for Food Allergy:

Identifying the Right Approach. Drugs. 2012; 72:1977-89

5. Keet CA, Wood RA. Emerging Therapies for Food Allergy. Journal of Clinical

Investigation. 2014;124:1880-6

6. Keet CA, Guerrerio PG, Wood RA. Pediatric Allergy. Immunol Allergy Clin

North Am. 2015; 35:xiii-xiv.

7. Matsui EC; Keet CA. Weighing the Evidence: Evaluating Epidemiologic Studies

in Allergy/Immunology. Journal of Allergy and Clinical Immunology. 2017, Feb;

2:127-134

8. Rachid R; Keet CA. Current Status and Unanswered Questions for Food Allergy

Treatments. JACI: In practice. 2017 Nov 18.

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9. Dunlop JH; Keet CA. Epidemiology of Food Allergy. Immunology Allergy

Clinics North America. 2018 Feb;38(1):13-25

Editorials

1. Keet CA and Wood RA. Baby – and toddler -- steps toward immunotherapy for

food allergy. Clin Exp Allergy. 2011; 41:1175-6

2. Matsui EC and Keet CA. Are all skin testing devices created equal? JACI-In

Practice. 2015; 894-5

3. Keet CA. A Call to Improve Standards for Reporting of Diagnostic Test Research

in Allergy. Journal of Allergy and Clinical Immunology. 2016; 137: 1761-3

4. Keet CA and McCormack M. Cardiac Asthma: An old term that may have new

meaning? JACI-In practice. 2016; 4: 924-5

5. Keet CA. Getting to the Root of the Food Allergy “Epidemic”, JACI: In Practice

2018,6(2):449-450

6. Rachid R, Keet CA. Food Allergy: What’s on the Menu in 2018? JACI: In

practice 2018 6(2):419-420

Case Reports

1. Keet CA, Fox CK, Margeta M, Marco E, Shane AL, Dearmond SJ, Strober JB,

Miller SP. Infant botulism, type F, presenting at 54 hours of life. Pediatr Neurol.

2005; 32:193-6.

2. Etzell JE, Keet CA, McDonald W, Banerjee A. Medulloblastoma simulating

acute myeloid leukemia: case report with a review of “myeloid antigen”

expression in nonhematopoietic tissues and tumors. J Pediatr Hematol Oncol.

2006; 28:703-10.

3. Robbins, KA, Keet CA. A case of gelfoam intraoperative anaphylaxis. Annals of

Allergy and Immunology. 2015; 114:531-3

Letters, correspondence

1. Keet CA and Wood RA. Risk Factors for Peanut Allergy. Journal of Allergy and

Clinical Immunology. 2009; 124:387

2. Keet C; Radano MC, Shreffler W. Reply to Lifschitz. JACI: In practice. 2014;

2:643-4

3. Keet C; Letter of response to Greenhawt et al. ‘LEAPing Through the Looking

Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction

on Peanut Tolerance after Early Peanut Introduction’. Allergy. 2017; 72(8); 1267-

1271

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Book Chapters, Monographs

1. Keet CA, Wood RA. New Aspects of Peanut and Tree Nut Allergy. In: Pawankar

R, Holgate S, and Rosenwasser LJ, eds. Allergy Frontiers. From Epigenetics to

Future Perspectives. Springer Japan KK, Tokyo, Japan 2009.

2. Keet CA, Wood, RA. Overview of Mucosal Immunology and the Development

of Oral Tolerance. In: James JM, Burks W, Eigenmann P, eds. Food Allergy.

Saunders, September 2011.

3. Keet CA, Wang J. Acute Reactions and Anaphylaxis to Foods. In: Sicherer S et

al. Food Allergy: Practical Diagnosis and Management. CRC Press. August 2013.

Teaching

Classroom instruction (dates, course title, role, location)

2012 Graduate Student Instructor, Principles of Epidemiology, Summer

Session, Johns Hopkins Bloomberg School of Public Health

2012, 2013 Graduate Immunology Medical Student Course, Guest Small

Group Leader, Johns Hopkins

2013- Clinical Research Methods for Post-doctoral Fellows in

Allergy/Immunology and Pulmonology, Co-director of course,

Johns Hopkins

2014- Small Group Leader, Introduction to Clinical Research, Institute

for Clinical and Translational Research, Johns Hopkins Medicine

2015- Graduate Immunology Medical Student Course, Coordinator for

Allergy Section, Lecturer, Small group leader

2016- Speed Aims Reviewer, Institute for Clinical and Translational

Research, Johns Hopkins Medicine

CME instruction (dates, course title, role, location)

2007-2015 Pediatric Trends, Speaker, Johns Hopkins

2009, 2010. Allergy Grand Rounds, Speaker, Johns Hopkins

2010 Pediatric Grand Rounds, Johns Hopkins

2014, 2015 Pediatrics for the Practicioner, “Food Allergy”, Johns Hopkins

2017 Pediatric Research, GTPCI Research Seminar

Mentoring

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Advisees:

1. Jessica Savage.

2. Emily McGowan.

3. Karen Robbins.

4. Shannon Seopaul.

5. Kristin Johnson.

6. Satya Narisety.

7. Marcella Radano.

8. Helen Hughes.

9. Mark Gorelik.

10. Huan He.

11. Joan Dunlop:

12. Suzanne Kochis.

13. Nicholas Jarbe.

14. Sarath Raju.

15. Emily Brigham.

16. Maria Guitteriez.

Thesis committees:

10/13 Huan He, PhD Student, Population, Family and Child Health, Johns

Hopkins Bloomberg School of Public Health

4/15-4/18 Emily McGowan, PhD Student, Graduate Training Program in

Clinical Investigation, Johns Hopkins Bloomberg School of Public Health.

(Advisor)

12/18 Amanda Driscoll, Final Exam Committee, PhD Candidate,

Epidemiology

Training grant participation:

1. Johns Hopkins Pediatric Allergy T32AI007056, 2010-

2. Burroughs Wellcome Fund, Maryland Genetics, Epidemiology and

Medicine (MD-GEM), 2014-

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3. Johns Hopkins Adult Allergy T32AI007007, 2010-2013

CLINICAL ACTIVITIES

Certification

9/30/2012 Maryland License Number: D0071006

2007 Diplomat, Pediatrics

American Board of Pediatrics

2010 Diplomat, Allergy and Immunology

American Board of Allergy and Immunology

Clinical (Service) Responsibilities (dates, specialty, role, time commitment)

2011-current. Pediatric Allergy Clinic. 10%

2010-current. Pediatric Allergy and Immunology Consult. 3-4 months/year.

2016. Pediatric Inpatient Attending. 2 weeks.

ORGANIZATIONAL ACTIVITIES

Editorial Activities (dates, role)

Guest Editor, Immunology and Allergy Clinics of North America, Pediatric

Allergy, 2014

Contributor, Best Articles in Pediatric Allergy and Immunology, Pediatrics 2008-

2015

Editorial Board, JACI: In Practice, 2015-

Editorial Board, Annals of Allergy, Asthma and Immunology, 2015-

Peer Reviewer, UpToDate, 2015-

Reviewer Board, Journal of Allergy and Clinical Immunology, 2016-2017

Editorial Board, Journal of Allergy and Clinical Immunology, 2017-

Advisory Committees:

2017 NIH Study Section, ZRG1 IMM-M (Immunology Study Section)

2017, June, November Ad Hoc Reviewer for NIH Study Section, SBIR (Small

Business)

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2018, January, Mail Reviewer for Kidney, Nutrition, Obesity and Diabetes Study

Section, NIH.

Professional Societies (date, membership, committees, role)

2018- Board Member, American Board of Allergy and Immunology, Co-chair

Maintenance of Certification/Continuous Assessment Pilot Exam Writing Committee

Journal Peer Review Activities

Reviewer for:

Journal of the American Medical Association

Journal of Allergy and Clinical Immunology

Thorax

Gastroenterology

Annals of Asthma, Allergy, and Immunology

Journal of Immunologic Methods

International Archives of Allergy and Immunology

Pulmonary Pharmacology and Therapeutics

American Journal of Clinical Dermatology

JACI: In Practice

Allergy

Clinical and Experimental Allergy

PLOSone

Acta Paediatrica

AAAAI Annual Meeting Abstracts

Pediatrics

British Medical Journal

Professional Societies (date, membership, committees, role)

2004 - American Academy of Pediatrics

2011 - Fellow, American Academy of Pediatrics

2007 - American Academy of Asthma, Allergy and Immunology, Member,

Subcommittee on Food Allergy

Committees at Johns Hopkins

2016- Pediatric Research Pipeline Committee

RECOGNITION

Awards, Honors (date, title, description, sponsor)

1997 Phi Beta Kappa

1998 High Honors and Distinction in General Scholarship

2000 University Fellowship for Graduate Study in Health and Medical Sciences

2003 American Medical Students Association Health Policy Fellowship

2004 Study Abroad Fellowship

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2004 Alpha Omega Alpha

2004 Sadie Berkov Award (awarded to top three female graduates of U.C.S.F.)

2010 American Academy of Pediatrics (AAP) Section on Allergy and

Immunology (SOAI) Outstanding Abstract Award - Fellow

2010 American Academy of Allergy, Asthma and Immunology (AAAAI)

FADDA Section Outstanding Abstract Award

2011 American Academy of Pediatrics (AAP) Section on Allergy and

Immunology (SOAI) Outstanding Abstract Award – Junior Faculty

2013 American Academy of Pediatrics (AAP) Section on Allergy and

Immunology (SOAI) Outstanding Abstract Award – Junior Faculty

2017 Outstanding Reviewer Award, Journal of Allergy and Clinical

Immunology

Invited Talks, Panels (date, title, venue, sponsor)

Johns Hopkins:

1. “Epidemiology of Food Allergy”, April 3, 2013, Johns Hopkins

Pulmonary/Allergic Diseases Conference

2. “Peanut Introduction in Infancy: 180 degrees on allergy prevention”, September

28, 2016, Pediatric Grand Rounds

3. 2016 Speed Aims Reviewer, ICTR, Johns Hopkins University

Local:

1. “Asthma in the 21st Century: Time to rethink the “inner-city asthma epidemic”?”

2016 Sinai Hospital Grand Rounds

2. “Prevention and Treatment of Food Allergy” A Woman’s Journey, November 11,

2017

3. “Prevention of Food Allergy”, Grand Rounds. Lancaster General Hospital 2/15/2018

National:

1. “New Therapies for Food Allergy”, March 20, 2011 Annual Meeting American

Academy of Allergy, Asthma and Immunology, San Francisco, California

2. “The PI’s Perspective on the FDA Audit”, March 1, 2012 Annual Meeting

American Academy of Allergy, Asthma and Immunology, Orlando, Florida

3. “Food Allergy: How Much Do We Really Know?” March 8, 2013 NIH STEP

Program, NIH, Bethesda, Maryland

4. “Is the Prevalence of Food Allergy Increasing, and, If So, Why?” April 5, 2013

Swineford Conference, Charlottesville, Virginia

5. “Born Under a Bad Sign; Gene-by-Environment Interactions in Food Allergy”

August 13, 2013 Stanford University, Palo Alto, California

6. “Update on Food Allergy” October 26, 2013, Annual Meeting, American

Academy of Pediatrics, Orlando, Florida

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7. “Are antibacterial products causing food allergy?” March 2, 2014, Colorado

Allergy and Asthma Society, Denver, Colorado

8. “Possible Environmental Causes of the Food Allergy Epidemic” March 3, 2014,

Denver Allergy/Immunology Rounds, National Jewish Hospital, Denver,

Colorado

9. “Epidemiology of Food Allergy” April 10, 2014, Food Safety Summit, session

“Food Allergen Control – Trends and Updates”, Baltimore, Maryland (this is the

largest food safety event in North America, panel organized by the FDA)

10. “Management of food allergy in schools and daycares”. October 13, 2014 Annual

Meeting, American Academy of Pediatrics, San Diego, California

11. “Oral and Sublingual Immunotherapy: Who Should Be Treated and With Which

Mode?” February 21, 2015 Annual Meeting, American Academy of Allergy,

Asthma and Immunology, Houston, Texas

12. “Challenges in the design of clinical trials for food allergy” May 20, 2015,

Society for Clinical Trials, Arlington, VA

13. “Hot Topics in Food Allergy” March 5, 2016 Annual Meeting, American

Academy of Allergy, Asthma and Immunology, Los Angeles, California

14. “From the Margins to the Mainstream: OIT in the now” New Jersey Allergy

Society. September 9, 2016

15. “The role of IgE in Eczema”. October 23, 2016. Annual Meeting, American

Academy of Pediatrics, San Francisco, CA

16. “How to Apply for and Obtain an NIH Grant for the New Investigator”. March 3,

2017. Annual Meeting, American Academy of Allergy, Asthma and Immunology,

Atlanta, Georgia

17. “Environmental Factors and Increasing Prevalence of Asthma and Allergic

Rhinitis: Improved Hygiene and the Hygiene Hypothesis”. March 5, 2017.

Annual Meeting, American Academy of Allergy, Asthma and Immunology,

Atlanta, Georgia

18. “AAP Year in Review Workshop: Hot Topics in Pediatric Allergy/Immunology,

Food allergy”. March 6, 2017. Annual Meeting, American Academy of Allergy,

Asthma and Immunology, Atlanta, Georgia

19. “Prevention of food allergy by diet and skin care”. September 17, 2017. Annual

Meeting, American Academy of Pediatrics, Chicago, IL.

20. "Moving Toward Precision Medicine in Atopic Dermatitis and Food Allergy,”

October 26, 2017. Annual Meeting, American College of Allergy, Asthma and

Immunology. Boston, MA

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21. Practical Aspects of Early Peanut Introduction: Who Needs to Be Screened and

How? Gordon Research Conference, January 1, 2018, Ventura, CA.

Internet:

1. “Advances in Food Allergy, 2012”, December 6, 2012, Webinar for American

Academy of Allergy, Asthma and Immunology-New Allergist and Immunologist

Association/Journal of Clinical Immunology

2. Video interview with Journal of Allergy and Clinical Immunology, 10/4/2013:

Long-term Follow-up of Milk Allergy.

3. Video interview with Contemporary Pediatrics, 4/22/2014: Temporal Trends and

Ethnic Disparities in Food Allergy

4. NEJM Expert Roundtable: Early introduction for prevention of food allergies.

3/2016

Other:

1. 6/3/2013: World Allergy Organization: Ask the expert “Food Desensitization by

SLIT”