congestive cardiac failure presentation and diagnosis
DESCRIPTION
Heart failure presentation and diagnosis A common problemTRANSCRIPT
Nothing can happen unless you first dream
Carl Sandburg
Congestive heart failurePresentation and Diagnosis
The most common reason for hospitalization in adults >65 years old
Dr Shahid Abbas
Consultant Interventional Cardiologist
Road Map– Definition
– Causes and pathophysiology
– Types of heart failure
– Compensatory mechanism of heart failure
– Clinical manifestations
– Classification of heart failure
– Diagnostic evaluation
– Management
Definition
A clinical syndrome that develops whenthe heart cannot maintain an adequatecardiac output
The heart pumps blood inadequately,leading to reduced blood flow, back-up(congestion) of blood in the veins andlungs Leading to
Other changes that may further weakenthe heart
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Etiology
• A syndrome of Pulmonary and/ or Systemic congestion due to C.O
• Heart is unable to pump enough blood to meet tissues O2 requirements
Pulmonary pressure fluid in alveoli (PULMONARY EDEMA)
Systemic pressure fluid in tissues
(PERIPHERAL EDEMA)
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Etiology
• Heart failure is caused by systemic hypertension in 75% of cases
• About one third of clients experiencing myocardial infarction also develop heart failure
• Structural heart changes, such as valvulardysfunction, cause pressure or volume overload on the heart
Predisposing Cardiac Diseases
• Myocardial infarction
• Chronic ischemia
• Cardiomyopathy
• Arrhythmias
• Diastolic dysfunction
• Valvular diseases
– Aortic Stenosis
– Mitral Stenosis
– Mitral Regurgitation
Causes of congestive heart failure (cont…)
• Severe lung disease (pulmonary hypertension)
• Severe anemia
• Overactive thyroid gland (hyperthyroidism)
• Underactive thyroid gland (hypothyroidism)
• Abnormal heart rhythms ( atrial fibrillation)
• Kidney failure
Cardiac Physiology(remember this?)
• CO = SV x HR
• HR: parasympathetic and sympathetic tone
• SV: preload, afterload, contractility
Preload
• Passive stretch of muscle prior to contraction
• Measurement: Swan-Ganz
– LVEDP
• Really a function of LVEDV
• Affected by compliance
– Low compliance = higher LVEDP @ lower LVEDV
– False high estimate of preload
• Frank-Starling right?
Afterload
• Force opposing/stretching muscle aftercontraction begins
• Measurement: SVR
• Really a function of:
– SVR
– Chamber radius (dilated cardiomyopathies)
– Wall thickness (hypertrophy)
Contractility
• Normal ability of the muscle to contract at a given force for a given stretch, independent of preload or afterload forces
• In other words:
– How healthy is your heart muscle?
• Ischemia, Hypertrophy (?), Muscle loss
CHF: the heart muscle
March 2013 ghennersdorf DGK ESC SES
CHF: the heart muscle sarcomere
March 2013 ghennersdorf DGK ESC SES
Pathophysiology
Renin + Angiotensinogen
Angiotensin I
Angiotensin II
Peripheral Vasoconstriction
Afterload
Cardiac Output
Heart Failure
Cardiac Workload
Preload
Plasma Volume
Salt & Water Retention
Edema
Aldosterone Secretion
Renin-angiotensin system
Heart Failure
• Pathophysiology
• A. Cardiac compensatory mechanisms
– 1.tachycardia
– 2.ventricular dilation-Starling’s law
– 3.myocardial hypertrophy
• Hypoxia leads to dec. contractility
Acute decompensated heart failure
Pulmonary edema, often life-threatening
• Early
– Increase in the respiratory rate
–Decrease in PaO2
• Later
–Tachypnea
–Respiratory acidemia
Pulmonary edema begins with an increased
filtration through the loose junctions of the
pulmonary capillaries.
As the intracapillary pressure increases, normally
impermeable (tight) junctions between the alveolar cells
open, permitting alveolar flooding to occur.
Acute Decompensated Heart Failure
(ADHF) Pulmonary Edema
END RESULT
FLUID OVERLOAD > Acute Decompensated Heart Failure (ADHF)/Pulmonary Edema
Medical Emergency!
Person literally drowning in secretions
Immediate Action Needed
MildMild
Drugs
Diet
Fluid Restriction
Heart Failure
(progression)
CDHF(Pulmonary Edema) Severe End Stage
Cardiogenic shockCardiomyopathy
Irreversible
Needs new ventricle
VADIABPVADIABP
Heart Transplant
Control With
Emergency-Upright, O2, morphine, etc
Ventricular remodeling
Classifying Heart Failure
• Anatomically
– Left versus Right
• Physiologically
– Systolic versus Diastolic
• Functionally
– How symptomatic is your patient?
Congestive heart failure
Types
• Left-sided heart failureThere are two types of left-sided heart failure
Systolic dysfunction
Diastolic dysfunction
• Right-sided heart failure
Left versus Right Failure
Left Heart Failure
- Dyspnea
- Dec. exercise tolerance
- Cough
- Orthopnea
- Pink, frothy sputum
Right Heart Failure
- Dec. exercise tolerance
- Edema
- HJR / JVD
- Hepatomegaly
- Ascites
Systolic versus Diastolic
Systolic– “can’t pump”
– Aortic Stenosis
– HTN
– Aortic Insufficiency
– Mitral Regurgitation
– Muscle Loss
• Ischemia
• Fibrosis
• Infiltration
Diastolic- “can’t fill”
– Mitral Stenosis
– Tamponade
– Hypertrophy
– Infiltration
– Fibrosis
Classification of heart failureNew York Heart Association (NYHA) Functional Classification
Symptoms% of patientsClass
No symptoms or limitations in ordinaryphysical activity
35%I
Mild symptoms and slight limitationduring ordinary activity
35%II
Marked limitation in activity evenduring minimal activity. Comfortable
only at rest
25%III
Severe limitation. Experiencessymptoms even at rest
5%IV
Heart FailureClinical Manifestations
• Acute decompensated heart failure (ADHF)
• Physical findings
• Orthopnea
• Dyspnea, tachypnea
• Use of accessory muscles
• Cyanosis
• Cool and clammy skin
•Physical findings•*Cough with frothy, blood-tinged sputum•Breath sounds: Crackles, wheezes, rhonchi •Tachycardia•Hypotension or hypertension
ADHF/Pulmonary Edema(advanced L side HF)
When PA WEDGE pressure is approx 30mmHg
– Signs and symptoms
• wheezing
• pallor, cyanosis
• Inc. HR and BP
• S3 gallop
• Rales,copious pink, frothy sputum
Congestive heart failure Clinical manifestations
– Symptoms (back up of blood and fluid)
– Dyspnea
– Orthopnea
– Reduced exercise tolerance, lethargy,fatigue
– Nocturnal cough
– Wheeze
– Ankle swelling
– Anorexia
Congestive heart failure Clinical manifestations ( cont…)
–Signs– Cachexia and muscle wasting
– Tachycardia
– Pulsus alternans
– Elevated jugular venous pressure
– Crepitations or wheeze
– Third heart sound
– Oedema
– Hepatomegaly (tender)
– Ascites
Clinical Data
• HEART SOUNDS!!!
• Systolic Murmurs
– Mitral Regurg
– Aortic Stenosis
• Diastolic Murmurs
– Mitral Stenosis
– Aortic Insufficiency
• S3: Rapid filling of a diseased ventricle
Symptoms
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PULMONARY EDEMA
Rapid fluid accumulation in lung spaces that has leaked from engorged pulmonary capillaries
Etiology – most common cause is sudden deterioration of LV function
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Cardiogenic Shock
Significant reduction in SV & CO causes drop in pressure & poor tissue perfusion a/r/o LV MI
• Clinical signs:
– BP, pulse, peripheral pulses
– confusion/ agitation (cerebral hypoxia)
– cold/ clammy skin
– urine output
– Resp distress
– Chest pain
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(R) SIDED HF
Blood “BACKS UP” into venous circulation. High oncotic pressure pushes fluids into tissues.
CLINICAL SIGNS:
CVP SUDDEN WT. GAIN
JVD DEPENDENT EDEMA
FATIGUE LIVER CONGESTION
LETHARGY ASCITES
ORTHOPNEA ANOREXIA
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What does this show?
Can You Have RVF Without LVF?
• What is this called?COR PULMONALE
What is present in this extremity, common to right sided HF?
Heart FailureComplications
• Pleural effusion
• Atrial fibrillation (most common dysrhythmia)
– Loss of atrial contraction (kick) -reduce CO by 10% to 20%
– Promotes thrombus/embolus formation inc. risk for stroke
– Treatment may include cardioversion, antidysrhythmics, and/or anticoagulants
Heart FailureComplications
• **High risk of fatal dysrhythmias (e.g., sudden cardiac death, ventricular tachycardia) with HF and an EF <35%
– HF lead to severe hepatomegaly, especially with RV failure
• Fibrosis and cirrhosis - develop over time
– Renal insufficiency or failure
Heart FailureDiagnostic Studies
• Primary goal- determine underlying cause
– History and physical examination( dyspnea)
– Chest x-ray
– ECG
– Lab studies (e.g., cardiac enzymes, BNP- (beta natriuretic peptide- normal value less than 100) electrolytes
– EF
Clinical Data
• CXR– Kerley’s lines : A and B
– Pulmonary Edema
– Cephalization
– Pleural Effusions (bilateral)
• EKG– Left atrial enlargement
– Arrhythmias
– Hypertrophy (left or right)
Cardiomegaly Pulm Oedema
Cardiomegaly/ventricular remodeling occurs as heart overworked> changes in size, shape, and function
of heart after injury to left ventricle. Injury due to acute myocardial infarction or due to causes that inc.
pressure or volume overload as in Heart failure
Clinical Data
• Laboratory Data
• Chemistry– Renal Function: Be Wary
• BNP– Used in ER departments the world over
– Good negative correlation
– Need baseline for positivity
– Pulmonary versus cardiac dyspnea
Transesophageal echocardiogram
TEE
But
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Goals of Treatment-ADHF/Pulmonary Edema)
MAD DOG• Improve gas exchange
– Start O2/elevate HOB/intubate
– Morphine –dec anxiety/afterload
– A- (airway/head up/legs down)
– D- (Drugs) Dig not first now- but drugs as • IV nitroglycerin; IV Nipride, Natrecor
– D- Diuretics
– O- oxygen /measure sats; • Hemodynamics, careful observation
– G- blood gases
– Think physiology