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Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention Section Division of Applied Research and Technology National Institute for Occupational Safety and Health The results reported in this paper represent the opinions of the authors and are not representative of the policies of the National Institute for Occupational Safety and Health.

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Page 1: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Comparison of Damage Risk Criteria Using the Albuquerque Blast

Overpressure Walkup Study Data

Comparison of Damage Risk Criteria Using the Albuquerque Blast

Overpressure Walkup Study Data William J. Murphy

Amir Khan

Peter B. ShawHearing Loss Prevention Section

Division of Applied Research and Technology

National Institute for Occupational Safety and Health

William J. Murphy

Amir Khan

Peter B. ShawHearing Loss Prevention Section

Division of Applied Research and Technology

National Institute for Occupational Safety and Health

The results reported in this paper represent the opinions of the authors and are not representative of the policies of the

National Institute for Occupational Safety and Health.

The results reported in this paper represent the opinions of the authors and are not representative of the policies of the

National Institute for Occupational Safety and Health.

Page 2: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Blast Overpressure StudiesBlast Overpressure Studies

Page 3: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

OutlineOutline Blast Overpressure Exposure Evaluations

MilStd 1474D

LAeq8hr Protected & Unprotected

AHAAH Warned & Unwarned

Statistical model for effects threshold

Population Averaged Model Audiometric Failures

Audiometric and Conditional Failures

Dose Response Curves

Blast Overpressure Exposure Evaluations

MilStd 1474D

LAeq8hr Protected & Unprotected

AHAAH Warned & Unwarned

Statistical model for effects threshold

Population Averaged Model Audiometric Failures

Audiometric and Conditional Failures

Dose Response Curves

Page 4: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Outline continuedOutline continued Exposure Assessment Comparisons

Threshold Estimates from BOP Study

Fitting Performance

Damage Risk Criteria Implications

MilStd 1474D: 177 dB Limit

LAeq8hr: 85 dBA Limit

AHAAH: 500 Auditory Hazard Unit (AHU) limit

Exposure Assessment Comparisons

Threshold Estimates from BOP Study

Fitting Performance

Damage Risk Criteria Implications

MilStd 1474D: 177 dB Limit

LAeq8hr: 85 dBA Limit

AHAAH: 500 Auditory Hazard Unit (AHU) limit

Page 5: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

MilStd 1474D Free-Field Exposure

MilStd 1474D Free-Field Exposure

170

175

180

185

190

195

200

170175

180185

190

612

25

50

100

612

25

50

100

612

25

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100

612

25

50

100

612

25

50

100

612

25

50

100

6

Mil-

Std

147

4D (

dB)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Mil-Std 1474D5 meter BOP Study 174

176 178 180 182 184 186 177 dB Threshold Limit

Page 6: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

170

175

180

185

190

195

200

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Mil-

Std

147

4D

(d

B)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Mil-Std 1474D5 meter BOP Study

Modified muff 174 176 178 180 190 195 200 177 dB Threshold Limit

170

175

180

185

190

195

200

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Mil-

Std

14

74D

(dB

)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Mil-Std 1474D1 meter BOP Study

Modified muff

170 175 180 185 190 190 195 177 dB Threshold Limit

170

175

180

185

190

195

200

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Mil-

Std

147

4D

(d

B)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Mil-Std 1474D3 meter BOP Study

Modified muff 175.5 176.0 176.5 177.0 177.5 178.0 180 177 dB Threshold Limit

Page 7: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

75

80

85

90

95

100

105

110

115

12

34

567

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

8 ho

ur E

quiv

alen

t Le

vel (

dBA

)

Exposure Level

Num

ber o

f Sho

ts

LAeq8hr with 85 dB Threshold1m BOP studyModified muff

90 95 100 105 110 100 105 110 115 85 dBA Threshold LimitHazardous Exposure

75

80

85

90

95

100

105

110

115

12

34

567

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

8 h

our

Equ

ival

ent

Lev

el (

dB

A)

Exposure Level

Num

ber o

f Sho

ts

LAeq8hr with 85 dB Threshold3 meter BOP Study

Modified muff

103.5 104.0 104.5 105.0 95 100 105 110 115 85 dBA Threshold LimitHazardous Exposure

75

80

85

90

95

100

105

110

115

12

34

567

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

8 h

our

Equ

ival

ent

Lev

el (

dB

A)

Exposure Level

Num

ber o

f Sho

ts

LAeq8hr with 85 dB Threshold5 meter BOP Study

Modified muff

90 95 100 105 95 100 105 110 115 85 dBA Threshold LimitSafe ExposureHazardous Exposure

Page 8: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

0

2000

4000

6000

8000

170175180185190612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Aud

itory

Haz

ard

Uni

ts (

AH

U)

Peak Exposure Level (dB)N

umbe

r of

Sho

ts

Warned AHAAH Analysis1 meter BOP study

Modified muff0 2000 4000 6000 8000 500 AHU Threshold LimitSafe ExposureHazardous Exposure

0

2000

4000

6000

8000

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Aud

itory

Haz

ard

Uni

ts (

AH

U)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Warned AHAAH Analysis3 meter BOP study

Modified muff

0 1000 2000 30004000 500 AHU Threshold LimitSafe ExposureHazardous Exposure

0

2000

4000

6000

8000

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Aud

itory

Haz

ard

Uni

ts (

AH

U)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Warned AHAAH Analysis5 meter BOP study

Modified muff

0 1000 2000 3000 4000 AHAAH 500 ARU ThresholdSafe ExposureHazardous Exposure

Page 9: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Statistical Analysis of BOP DataStatistical Analysis of BOP Data

Obtained the waveforms from Data Archive from USAARL-MRMC and USARL – HRED MILSTD 1474D – B duration (also computed A & C

durations) LAeq8hr – Protected and Unprotected AHAAH model – Protected Warned and Unwarned

Checked against Chan et al. 2001, Ahroon & Patterson 2005, Price (2005), Jokel (2007)

Obtained the injury data from USAARL-MRMC Checked the injury data against 1999 Contractor

report DAMD17-96-6007

Obtained the waveforms from Data Archive from USAARL-MRMC and USARL – HRED MILSTD 1474D – B duration (also computed A & C

durations) LAeq8hr – Protected and Unprotected AHAAH model – Protected Warned and Unwarned

Checked against Chan et al. 2001, Ahroon & Patterson 2005, Price (2005), Jokel (2007)

Obtained the injury data from USAARL-MRMC Checked the injury data against 1999 Contractor

report DAMD17-96-6007

Page 10: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Applied a General Estimating Equations to evaluate the Population Averaged effects using xtgee in Stata.

Represents the response pattern of the population as a whole

Makes no assumptions regarding propagation of failure through to other exposure levels

Tells us nothing about the chances of an individual subject failing within the exposure.

Tells us about the chance of having a failure in the population.

Applied a General Estimating Equations to evaluate the Population Averaged effects using xtgee in Stata.

Represents the response pattern of the population as a whole

Makes no assumptions regarding propagation of failure through to other exposure levels

Tells us nothing about the chances of an individual subject failing within the exposure.

Tells us about the chance of having a failure in the population.

Statistical Analysis of BOP DataStatistical Analysis of BOP Data

0 1ˆ ˆ

1 ijxf

e

Page 11: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Mil STD 1474 DMil STD 1474 D00

.05

0.2

0.4

0.6

0.8

1.0

Failu

re R

ate

150 160 170 180 190 200 210dB

95% confidence limits GEE population-average

Audiometric FailureMIL STD 1474D

00.0

50.

20.

40.

60.

81.

0Fa

ilure

Rat

e

150 160 170 180 190 200 210dB

95% confidence limits GEE population-average

Audiometric or Conditional FailureMIL STD 1474D

185 dB193 dB

Page 12: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

LAeq8hr Unprotected LevelsLAeq8hr Unprotected Levels00

.05

0.2

0.4

0.6

0.8

1.0

Failu

re R

ate

100 105 110 115 120 125 130 135 140dB

95% confidence limits GEE population-average

Audiometric FailureLAeq_8hr: Unprotected

00.0

50.

20.

40.

60.

81.

0Fa

ilure

Rat

e

100 105 110 115 120 125 130 135 140dB

95% confidence limits GEE population-average

Audiometric or Conditional FailureLAeq_8hr: Unprotected

115 dB124 dB

Page 13: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

LAeq8hr Protected LevelsLAeq8hr Protected Levels00

.05

0.2

0.4

0.6

0.8

1.0

Failu

re R

ate

80 85 90 95 100 105 110 115 120dB

95% confidence limits GEE population-average

Audiometric FailureLAeq_8hr: Protected

00.0

50.

20.

40.

60.

81.

0Fa

ilure

Rat

e

80 85 90 95 100 105 110 115 120dB

95% confidence limits GEE population-average

Audiometric or Conditional FailureLAeq_8hr: Protected

101 dB109 dB

Page 14: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

AHAAH Unwarned ModelAHAAH Unwarned Model00

.05

0.2

0.4

0.6

0.8

1.0

Failu

re R

ate

0 5000 10000 15000 20000 25000 30000AHU

95% confidence limits GEE population-average

Audiometric FailureAHAAH: Unwarned

00.0

50.

20.

40.

60.

81.

0Fa

ilure

Rat

e

0 5000 10000 15000 20000 25000 30000AHU

95% confidence limits GEE population-average

Audiometric or Conditional FailureAHAAH: Unwarned

3053 AHU10109 AHU

Page 15: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

AHAAH Warned ModelAHAAH Warned Model00

.05

0.2

0.4

0.6

0.8

1.0

Failu

re R

ate

0 1000 2000 3000 4000 5000 6000 7000 8000AHU

95% confidence limits GEE population-average

Audiometric FailureAHAAH: Warned

00.0

50.

20.

40.

60.

81.

0Fa

ilure

Rat

e

0 1000 2000 3000 4000 5000 6000 7000 8000AHU

95% confidence limits GEE population-average

Audiometric or Conditional FailureAHAAH: Warned

718 AHU2480 AHU

Page 16: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

5% Failure Thresholds L(95,95)5% Failure Thresholds L(95,95)

Damage Risk Criterion

Audiometric Failures

Audiometric & Conditional

Failures

AHAAH Warned 2480 AHU 718 AHU

AHAAH Unwarned 10109 AHU 3053 AHU

LAeq8hr Unprotected 124 dB 115 dB

LAeq8hr Protected 109 dB 101 dB

MilStd 1474D 193 dB 185 dB

Page 17: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Five Exposure Assessments Compared

Five Exposure Assessments Compared

Damage Risk Criterion

Audiometric Failures

Audiometric & Conditional

Failures

LAeq8hr Unprotected 273.73 630.26

MilStd 1474 D 282.01 636.25

AHAAH Unwarned 304.51 650.85

LAeq8hr Protected 305.80 650.05

AHAAH Warned 307.13 653.99

QIC: Lower value indicates a better fitQIC = Quasi Likelihood under the independence model Information

Criterion

Page 18: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Mil-Std ObservationsMil-Std Observations

Mil-Std 1474D

L(95,95) with No Presumed Auditory Failures Chan : L(95,95) = 193 dB NIOSH : L(95,95) = 193 dB

Chan’s analysis: Presumed Auditory Failures Add 9 dB for threshold of L(95,95) = 186 dB

NIOSH analysis (Auditory & Conditional Failures) L(95,95) = 185 dB. Add 8 dB for Population Average threshold for

the L(95,95) lower confidence bound.

Mil-Std 1474D

L(95,95) with No Presumed Auditory Failures Chan : L(95,95) = 193 dB NIOSH : L(95,95) = 193 dB

Chan’s analysis: Presumed Auditory Failures Add 9 dB for threshold of L(95,95) = 186 dB

NIOSH analysis (Auditory & Conditional Failures) L(95,95) = 185 dB. Add 8 dB for Population Average threshold for

the L(95,95) lower confidence bound.

Page 19: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

LAeq8hr ObservationsLAeq8hr Observations LAeq8hr Protected versus Unprotected

French Weapon Noise Criteria:

LAeq8hr < 85 dB Unprotected

Chan’s analysis without presumed failures LAeq8hr < 100 dB Protected (assumed 15 dB for protectors)

Unprotected limit 124 dB without presumed failures

NIOSH analysis without presumed failures

14 dB HPD effect for Protection

Unprotected limit: 124 dB Audiometric Failures

Unprotected limit: 115 dB Aud. & Cond. Failures

Protected limit: 101 dB Aud. & Cond. Failures

LAeq8hr Protected versus Unprotected

French Weapon Noise Criteria:

LAeq8hr < 85 dB Unprotected

Chan’s analysis without presumed failures LAeq8hr < 100 dB Protected (assumed 15 dB for protectors)

Unprotected limit 124 dB without presumed failures

NIOSH analysis without presumed failures

14 dB HPD effect for Protection

Unprotected limit: 124 dB Audiometric Failures

Unprotected limit: 115 dB Aud. & Cond. Failures

Protected limit: 101 dB Aud. & Cond. Failures

Page 20: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

AHAAH ObservationsAHAAH Observations NIOSH Analysis L(95,95) Audiometric

failures (no presumed failures) Unwarned Threshold = 10109 AHU Warned Threshold = 2480 AHU

NIOSH Analysis L(95,95) Audiometric and Conditional Failures (no presumed failures) Unwarned Threshold = 3053 AHU Warned Threshold = 718 AHU

AHAAH Model proposes a 500 AHU Limit which is more conservative than the data suggest

NIOSH Analysis L(95,95) Audiometric failures (no presumed failures) Unwarned Threshold = 10109 AHU Warned Threshold = 2480 AHU

NIOSH Analysis L(95,95) Audiometric and Conditional Failures (no presumed failures) Unwarned Threshold = 3053 AHU Warned Threshold = 718 AHU

AHAAH Model proposes a 500 AHU Limit which is more conservative than the data suggest

Page 21: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Concerns for AHAAH ModelConcerns for AHAAH Model

Predictions of Hazard at Levels 3 & 4 not really tested in BOP study.

Experiments can be designed to test this.

Predictions of Hazard at Levels 3 & 4 not really tested in BOP study.

Experiments can be designed to test this.

Page 22: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

0

2000

4000

6000

8000

170175180185190612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Aud

itory

Haz

ard

Uni

ts (

AH

U)

Peak Exposure Level (dB)N

umbe

r of

Sho

ts

Warned AHAAH Analysis1 meter BOP study

Modified muff0 2000 4000 6000 8000 500 AHU Threshold LimitSafe ExposureHazardous Exposure

75

80

85

90

95

100

105

110

115

12

34

567

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

8 ho

ur E

quiv

alen

t Le

vel (

dBA

)

Exposure Level

Num

ber o

f Sho

ts

LAeq8hr with 85 dB Threshold1m BOP studyModified muff

90 95 100 105 110 100 105 110 115 85 dBA Threshold LimitHazardous Exposure

170

175

180

185

190

195

200

170175

180185

190

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

612

25

50

100

Mil-

Std

147

4D (

dB)

Peak Exposure Level (dB)

Num

ber o

f Sho

ts

Mil-Std 1474D1 meter BOP Study

Modified muff

170 175 180 185 190 190 195 177 dB Threshold Limit

Page 23: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Concerns for AHAAH ModelConcerns for AHAAH Model Justification for 500 AHU as a threshold limit

Warned limit 718 or 2480 AHU – Population Average, L(95, 95)

Unwarned Limit 3053 or 10109 AHU – Population Average, L(95,

95)

Validation of the Warned/Unwarned middle ear

No consideration given for adaptation/fatigue

Model turns Warned condition ON but not OFF

Justification for 500 AHU as a threshold limit

Warned limit 718 or 2480 AHU – Population Average, L(95, 95)

Unwarned Limit 3053 or 10109 AHU – Population Average, L(95,

95)

Validation of the Warned/Unwarned middle ear

No consideration given for adaptation/fatigue

Model turns Warned condition ON but not OFF

Page 24: Comparison of Damage Risk Criteria Using the Albuquerque Blast Overpressure Walkup Study Data William J. Murphy Amir Khan Peter B. Shaw Hearing Loss Prevention

Questions?Questions?

William Murphy

4676 Columbia Parkway, MS C-27

Cincinnati, OH 45226-1998

[email protected]

513-533-8125

William Murphy

4676 Columbia Parkway, MS C-27

Cincinnati, OH 45226-1998

[email protected]

513-533-8125