Cholera

Ryan Nguyen

Vibrio Cholerae (scanning EM)

Our star: Vibrio Cholerae

I am a Gram-Negative, curved rod shaped bacteria

Cholera has been killing millions of people for centuries

Cholera is an Ancient Disease

It is estimated from 1817-1923 Cholera killed millions of people

As late as the 1800s, causes and cures of Cholera remained mysterious

John Snow disproved the theory that Cholera was caused by Miasma

John Snow

Snow’s studies identified the source of the outbreak to be from the public water supply

This occurred 30 Years before Robert Koch isolated Vibrio

Cholerae

In 1854 while working in FlorenceI isolated the cholera bacillus Vibrio Cholerae.

Filippo Pancini

Cholera stems from

the ingestion of food or water

contaminated with the bacterium Vibrio

cholerae

Here’s how it all works

Cholera is present world-wide but

Prevalence differs dramatically

There are still an estimated 3–5 million

cholera cases and 100 000–120 000

deaths due to cholera per year.

Symptoms of Untreated Cholera

• Diarrhea

• Nausea

• Vomiting

• Dehydration

The Cholera Dipstick Test is now used for rapid diagnosis

The best way to treat Cholera is through Rehydration

Works Cited• http://jhyoung.myweb.uga.edu/Waterborne.html• http://fineartamerica.com/featured/vibrio-cholerae-bacterium-tem-dr-kari-

lounatmaa.html• http://www.docstoc.com/docs/80526988/Cholera-The-Biography• http://www.sewerhistory.org/grfx/disease/cholera/cholera.html• http://globalvoicesonline.org/2011/02/26/bangladesh-clinical-trial-of-a-cholera-

vaccine-raises-some-questions/• http://blog.rtwilson.com/john-snows-famous-cholera-analysis-data-in-modern-gis-

formats/• http://en.wikipedia.org/wiki/File:Filippo_Pacini_1870.jpg• http://www.freedomsphoenix.com/Article/078467-2010-11-11-cholera-outbreak-hits-

port-au-prince.htm• http://www.nature.com/nrmicro/journal/v7/n10/fig_tab/nrmicro2204_F2.html• http://www.nathnac.org/pro/factsheets/cholera.htm• http://ocw.tufts.edu/Content/2/lecturenotes/191262/191297• http://photos.dailyme.com/post/1704569244/a-boy-suffering-from-cholera-symptoms-

lies• http://www.span.co.in/ProductList/ProductDetails/REAGENTS/279-

Crystal_VC_(Dipstick).HTM• http://www.doctorswithoutborders.org/news/article.cfm?id=5459&cat=voice-from-

the-field