cheminform abstract: synthesis of some acridone alkaloids and related compounds

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  • 1998 alkaloids

    alkaloidsU 0600

    01 - 234Synthesis of Some Acridone Alkaloids and Related Compounds. The previously reported four-step synthesis of acridinediones (I) is extendedby an efficient aromatization with PdC leading to 1-hydroxyacridones (II).This new method, along with demethylation with HBr [concomitant loss ofthe ester group in (IIb)], provides a useful route to various methoxy- andhydroxy-substituted acridones. (CHEN, J.-J.; DEADY, L. W.; MACKAY,M. F.; Tetrahedron 53 (1997) 37, 12717-12728; Dep. Chem., La Trobe Univ.,Bundoora, Melbourne, Victoria 3083, Australia; EN)

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