cheminform abstract: synthesis of nectrisine and related compounds, and their biological evaluation

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1999 antibiotics antibiotics U 1200 39 - 205 Synthesis of Nectrisine and Related Compounds, and Their Biological Evaluation. Nectrisine (I), 4-epi-nectrisine (II), and 5-deoxynectrisine (III) are prepared as potential glucosidase inhibitors. Biological evaluations re- veal that all three compounds are highly active against yeast α-glucosidase. (KIM, YONG JIP; TAKATSUKI, AKIRA; KOGOSHI, NAOTO; KITAHARA, TAKESHI; Tetrahedron 55 (1999) 28, 8353-8364; Dep. Appl. Biol. Chem., Univ. Tokyo, Bunkyo, Tokyo 113, Japan; EN) 1

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Page 1: ChemInform Abstract: Synthesis of Nectrisine and Related Compounds, and Their Biological Evaluation

1999 antibiotics

antibioticsU 1200

39 - 205Synthesis of Nectrisine and Related Compounds, and Their BiologicalEvaluation. — Nectrisine (I), 4-epi-nectrisine (II), and 5-deoxynectrisine(III) are prepared as potential glucosidase inhibitors. Biological evaluations re-veal that all three compounds are highly active against yeast α-glucosidase. —(KIM, YONG JIP; TAKATSUKI, AKIRA; KOGOSHI, NAOTO; KITAHARA,TAKESHI; Tetrahedron 55 (1999) 28, 8353-8364; Dep. Appl. Biol. Chem.,Univ. Tokyo, Bunkyo, Tokyo 113, Japan; EN)

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