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1999 alkaloids alkaloids U 0600 52 - 215 Stereocontrolled Total Synthesis of (±)-Catharanthine via Radical- Mediated Indole Formation. — The stereocontrolled total synthesis of racemic catharanthine (IV) involves the formation of indole (III) via radical cy- clization as key step. — (REDING, MATTHEW T.; FUKUYAMA, TOHRU; Org. Lett. 1 (1999) 7, 973-976; Grad. Sch. Pharm. Sci., Univ. Tokyo, Bunkyo, Tokyo 113, Japan; EN) 1

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Page 1: ChemInform Abstract: Stereocontrolled Total Synthesis of (.+-.)-Catharanthine via Radical-Mediated Indole Formation

1999 alkaloids

alkaloidsU 0600

52 - 215Stereocontrolled Total Synthesis of (±)-Catharanthine via Radical-Mediated Indole Formation. — The stereocontrolled total synthesis ofracemic catharanthine (IV) involves the formation of indole (III) via radical cy-clization as key step. — (REDING, MATTHEW T.; FUKUYAMA, TOHRU;Org. Lett. 1 (1999) 7, 973-976; Grad. Sch. Pharm. Sci., Univ. Tokyo, Bunkyo,Tokyo 113, Japan; EN)

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