cheminform abstract: stereocontrolled synthesis of (-)-5,11-dideoxytetrodotoxin
TRANSCRIPT
2001 other bioactive products
other bioactive productsU 1300
37 - 235Stereocontrolled Synthesis of (-)-5,11-Dideoxytetrodotoxin. — Thekey steps of the synthesis are a novel hydroxylation at the C-8 position withneighboring group participation of trichloroacetamide, a highly stereoselectiveaddition of acetylide as an equivalent of carboxylic acid, and a new guanidinesynthesis from trichloroacetamide. — (ASAI, MASANORI; NISHIKAWA,TOSHIO; OHYABU, NORIO; YAMAMOTO, NOBORU; ISOBE, MINORU;Tetrahedron 57 (2001) 21, 4543-4558; Lab. Org. Chem., Grad. Sch. Bioagric.Sci., Nagoya Univ., Chikusa, Nagoya 464, Japan; EN)
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