cheminform abstract: practical methodology for the asymmetric synthesis of organofluorine compounds
TRANSCRIPT
1998 halogen compounds
halogen compounds (acyclic compounds)P 0030
21 - 071Practical Methodology for the Asymmetric Synthesis of Organofluo-rine Compounds. — Pseudoephedrine α-fluoroacetamide (III), preparedby a novel procedure, can be alkylated with high diastereoselectivity usingreactive alkylating agents (IV). The alkylation products can be hydrolyzed toenantioenriched α-fluorocarboxylates (VI). — (MYERS, A. G.; MCKINSTRY,L.; BARBAY, J. K.; GLEASON, J. L.; Tetrahedron Lett. 39 (1998) 11,1335-1338; Dep. Chem. Eng., Calif. Inst. Technol., Pasadena, CA 91125, USA;EN)
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