cheminform abstract: general method for the synthesis of cyclic peptidomimetic compounds

2001 amino acids, peptides amino acids, peptides U 0400 48 - 149 General Method for the Synthesis of Cyclic Peptidomimetic Com- pounds. — Cyclic peptides of type (V) joined by an alkyl linker and bearing a Weinreb amide at the C-terminus are prepared by a general strategy. These are converted at the C-terminus to activated derivatives [cf. (VII)] using LiCl to solubilize the starting cyclic peptide. — (WALKER, MICHAEL A.; JOHNSON, TIMOTHY; Tetrahedron Lett. 42 (2001) 34, 5801-5804; Bristol-Myers Squibb Pharm. Res. Inst., Wallingford, CT 06492, USA; EN) 1

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Page 1: ChemInform Abstract: General Method for the Synthesis of Cyclic Peptidomimetic Compounds

2001 amino acids, peptides

amino acids, peptidesU 0400

48 - 149General Method for the Synthesis of Cyclic Peptidomimetic Com-pounds. — Cyclic peptides of type (V) joined by an alkyl linker andbearing a Weinreb amide at the C-terminus are prepared by a general strategy.These are converted at the C-terminus to activated derivatives [cf. (VII)]using LiCl to solubilize the starting cyclic peptide. — (WALKER, MICHAELA.; JOHNSON, TIMOTHY; Tetrahedron Lett. 42 (2001) 34, 5801-5804;Bristol-Myers Squibb Pharm. Res. Inst., Wallingford, CT 06492, USA; EN)

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