1999 alkaloids

alkaloidsU 0600

14 - 254A Novel Route to (±)-Aspidospermidine: First Application of”Radical-Polar Crossover” Reactions to Total Synthesis. — Totalsynthesis of the alkaloid aspidospermidine (XII) is achieved by a route involvingthe known tetrathiafulvalene-induced radical cyclization of the diazonium salt(I) as the key step. — (CALLAGHAN, OWEN; LAMPARD, CHRISTOPHER;KENNEDY, ALAN R.; MURPHY, JOHN A.; Tetrahedron Lett. 40 (1999) 1,161-164; Dep. Pure Appl. Chem., Univ. Strathclyde, Glasgow G1 1XL, UK; EN)

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