Upload File

cheminform abstract: a novel efficient and stereoselective synthesis of cis- or...

  • Home
  • Documents
  • ChemInform Abstract: A Novel Efficient and Stereoselective Synthesis of cis- or trans-2,5-Disubstituted Tetrahydrofurans
1
2002 furan derivatives furan derivatives R 0060 09 - 112 A Novel Efficient and Stereoselective Synthesis of cis- or trans-2,5- Disubstituted Tetrahydrofurans. — A general route to either cis- or trans-2,5-disubstituted tetrahydrofurans is described using the nucleophilic addition of organo-lithium derivatives (III) to tricyclic lactones followed by a highly stereo-controlled acid-assisted reduction of the hemiketal formed as the key steps. — (SHI, HONGXIN; LIU, HUAZHANG; BLOCH, ROBERT; MANDVILLE, GERARD; Tetrahedron 57 (2001) 45, 9335-9341; Lab. Carbocy- cles, CNRS, Inst. Chim. Mol. Orsay, Univ. Paris-Sud, F-91405 Orsay, Fr.; EN) 1

Upload: hongxin-shi

Post on 06-Jun-2016

214 views

Category:

Documents


1 download

Report

TRANSCRIPT

Page 1: ChemInform Abstract: A Novel Efficient and Stereoselective Synthesis of cis- or trans-2,5-Disubstituted Tetrahydrofurans

2002 furan derivatives

furan derivativesR 0060

09 - 112A Novel Efficient and Stereoselective Synthesis of cis- or trans-2,5-Disubstituted Tetrahydrofurans. — A general route to either cis- ortrans-2,5-disubstituted tetrahydrofurans is described using the nucleophilicaddition of organo-lithium derivatives (III) to tricyclic lactones followed bya highly stereo-controlled acid-assisted reduction of the hemiketal formed asthe key steps. — (SHI, HONGXIN; LIU, HUAZHANG; BLOCH, ROBERT;MANDVILLE, GERARD; Tetrahedron 57 (2001) 45, 9335-9341; Lab. Carbocy-cles, CNRS, Inst. Chim. Mol. Orsay, Univ. Paris-Sud, F-91405 Orsay, Fr.; EN)

1

Part I. Conformational analysis of 1,4-disubstituted

Asymmetric synthesis of 2,2-disubstituted chromanols ... · Asymmetric synthesis of 2,2-disubstituted chromanols - Novel approaches to Vitamin E analogues. Inauguraldissertation zur

Syntheses of 3,4-Disubstituted Pyrroles and Furans …pyrrole derivatives in good yields. The 3,4-disubstituted furan analogues can also be available from 3,5,5-trimethyl-2,3-epoxycyclohexan-1-ones

METHODOLOGY Ecientiterativevirtualscreening with … · 2018. 3. 1. · Ahmed et al. J Cheminform Page4of8 10contain‘high-scoring’ligands.eunassignedbin3is excludedfromtraining.Figure

2, 2 disubstituted glycerol and glycerol-like compounds

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives ... · ORIGINAL ARTICLE Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated

MASTERARBEIT “1,4-Disubstituted 1,2,3-triazoles as novel ligand …othes.univie.ac.at/36046/1/2015-02-03_0906333.pdf · 2015-02-17 · MASTERARBEIT “1,4-Disubstituted 1,2,3-triazoles

2,3-Disubstituted-1,4-naphthoquinones containing an

In silico studies of 2,5-disubstituted furans as active

Synthesis of r-Disubstituted Aryl Amines by Rhodium ...€¦ · ORGANIC LETTERS 2011 Vol. 13, No. 20 5576–5579 Synthesis of r,r-Disubstituted Aryl Amines by Rhodium-Catalyzed Amination

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding

Formation of 1,5-Disubstituted 2-hydroxypyrroles via

Discovery of 4,6-disubstituted pyrimidines as potent ...Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the Heat Shock Factor (HSF1) stress pathway ... Via Madonna

Mono-and disubstituted methyltin, butyltin and octyltin ...inchem.org/documents/cicads/cicads/cicad73.pdf · Mono- and disubstituted methyltin, butyltin, and octyltin compounds 1

A green, solvent-free one-pot synthesis of disubstituted

Synthesis of some disubstituted 3,4,5,6,-tetrafluorobenzenes...Synthesis of Some Disubstituted 3,4,5,6, Tetrafluorobenzenes 1, 2 Walter 1. Pummer, Roland E. Florin, and Leo A. Wall

ChemInform RxnFinder

Ring-opening addition reactions of 11-disubstituted

Disubstituted 4-Chloro-3-nitrophenylthiourea Derivatives: Antimicrobial and Cytotoxic ... · 2019. 6. 13. · molecules Article Disubstituted 4-Chloro-3-nitrophenylthiourea Derivatives:

Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in … · 2016. 9. 16. · 1 Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents Juana

Synthesis of New Schiff Bases and 2, 3-Disubstituted -1, 3 ...article.aascit.org/file/pdf/9400818.pdf · hree series of Schiff Bases and 2,3-disubstituted-1,3-thiazolidin-4-one derivatives

Utilization of 1,5-disubstituted tetrazole for …Utilization of 1,5-disubstituted tetrazole for preparation of furo[2,3-d]imidazole L. ŠTTORÁNYI, M. PEEVA, and S. SEKRETÁR Department

Oxidative Heck desymmetrisation of 2,2-disubstituted

Electrochemical properties of 1,3-disubstituted methyl ...journals.tubitak.gov.tr/chem/issues/kim-13-37-1/kim-37-1-4-1203-22.pdfElectrochemical properties of 1,3-disubstituted methyl

Synthesis and Photophysical Properties of 9,10-Disubstituted ...Synthesis and Photophysical Properties of 9,10-Disubstituted Anthracenes Roberto Pizzoferrato1*, Pietro Tagliatesta2,

Certain 2, 5-diaryl tetrahydrofurans and analogs thereof as PAF

MONO- AND DISUBSTITUTED METHYLTIN, …Mono- and disubstituted methyltin, butyltin, and octyltin compounds 1 FOREWORD Concise International Chemical Assessment Documents (CICADs) are

Recent advances in the synthesis of tetrahydrofurans and … la... · 2020. 12. 10. · Tetrahedron report 1117 Recent advances in the synthesis of tetrahydrofurans and applications

1,2-Disubstituted Ferrocenyl Carbohydrate Chloroquine ... · S1 Supporting Information 1,2-Disubstituted Ferrocenyl Carbohydrate Chloroquine Conjugates as Potential Antimalarial Agents

Enantioselective Synthesis of 2,2-Disubstituted Terminal Epoxides via Catalytic Asymmetric Corey

Multiple Linear Regression Study of 2,4-Disubstituted 1,5 ... · Considering the scope for further studies on diazepine derivatives we have synthesized some new 2,4-disubstituted

The Synthesis of N,N-Disubstituted Hydroxylamines Via

Open Access C S :kextractionkandjre-use(ability)k ... · Nguyenjet al. J Cheminform Pagek2kofk9 forthegenerationofcalculatedinformationandidenti-ers.AlthoughtherearesomealternativestoChemDraw,

1,2 – Disubstituted Aromatics: Directed Ortho Metalation

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce … · ORIGINAL ARTICLE Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53