2002 quinoline derivatives

quinoline derivativesR 0410

08 - 143A Modified Niementowski Reaction for the Synthesis of 4-Hydroxyquinoline and Its Related Compounds. — Iminoketene (II),formed by treatment of anthranilic acid (I) with thionyl chloride, undergoescycloaddition with ketones, presumably via an enol, to give quinoline derivatives[cf. (IV), (VI)] (6 samples) in good yields. — (SON, JAE KEUN; KIM,SEUNG ILL; JAHNG, YURNGDONG; Heterocycles 55 (2001) 10, 1981-1986;Coll. Pharm., Yeungnam Univ., Kyongsan 712-749, S. Korea; EN)

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