building relationships with veterinarians - amazon s3 ?· building relationships with...

Download Building Relationships with Veterinarians - Amazon S3 ?· Building Relationships with Veterinarians…

Post on 31-Aug-2018

212 views

Category:

Documents

0 download

Embed Size (px)

TRANSCRIPT

  • Veterinary

    KevinOberlander,RPhDeborahClark,RPhChrisSimmons,RPhInternationalSeminar

    Houston,TXNovember1012,2016

    2016. All Rights Reserved. 1

  • BuildingRelationshipswithVeterinarians

    KevinOberlander,RPh

    2016. All Rights Reserved. 2

  • UnderstandCompanionAnimalOwnerCompassion

    Areyouapetowner? Issomeoneonyourstaffapetowner? Understand$$$$investedinpets Sympathetictolossofcompanionanimals

    2016. All Rights Reserved. 3

  • BecomePartoftheCompanionAnimalCommunity

    Volunteer: HumaneSociety Localzoo Rescueprojects

    Support: Vetauxiliaryschools Techs VetandPreVetschools

    2016. All Rights Reserved. 4

  • 2016. All Rights Reserved. 5

  • BuildingRelationships/Trust

    Doyouknowyourcompounder? Doyouknowyourveterinariansandtheirstaff? Donotcompetewithveterinarians Offerpharmacyservicestoveterinarianclinicalstaff

    Smalldiscounts Healthandwellnessservices/immunizations

    Beconsistentwithmessageandtimelywithclinicvisits Attendandsponsorstateassociationmeetings

    Sponsor/advertiseinmembershipdirectory

    2016. All Rights Reserved. 6

  • 2016. All Rights Reserved. 7

  • 2016. All Rights Reserved. 8

  • MarketingIdeas

    Videoconferencing Offertobepartofthecareteam SocialMedia

    Facebook Twitter YouTube Instagram

    2016. All Rights Reserved. 9

  • 2016. All Rights Reserved. 10

  • AdditionalRelationships

    Animal/petsupplystores HumaneSocieties Animalshelters Animalrescue Groomers Rxcustomersmakeitknownthatyoucompoundforanimals/pets

    2016. All Rights Reserved. 11

  • RescuedAnimals

    2016. All Rights Reserved. 12

  • Patients

    2016. All Rights Reserved. 13

  • Questions?

    2016. All Rights Reserved. 14

  • VeterinaryFormulationChallenges:CommonQuestionstoPCD

    DeborahH.Clark,RPh

    2016. All Rights Reserved. 15

  • DisclosureDeborahClark,RPh,andChrisSimmons,RPh,VicePresidentofCreativeDevelopment,areemployedbyPCCA.Conflictofinterestwasresolvedthroughpeerreviewofslidecontent.

    ProfessionalEducationServicesGroupstaffhavenofinancialinterestorrelationshipstodisclose.

    2016. All Rights Reserved. 16

  • Disclosure

    ThiscontinuingeducationactivityismanagedandaccreditedbyProfessionalEducationServicesGroup.NeitherPESGnoranyaccreditingorganizationsupportsorendorsesanyproductorservicementionedinthisactivity.

    2016. All Rights Reserved. 17

  • EducationalGrantSupport

    ThiscontinuingeducationactivityissupportedbyaneducationalgrantfromPCCA.

    2016. All Rights Reserved. 18

  • LearningObjectives

    Attheconclusionofthisactivity,theparticipantwillbeableto: Discussinnovativecompoundingtechniques,formulations,andanimalpatientcasestudies.

    DiscussthelatesttreatmentmodalitiesanduniquecompoundedoptionsgleanedfrommembercallstoPCD.

    Describedifferentdermatologicalconditionsaffectingcatsanddogs.

    2016. All Rights Reserved. 19

  • AppropriateUseofOilVehicles

    2016. All Rights Reserved. 20

  • Number1VetQuestioninPCD

    WouldIbeabletoput_________inafixedoilsuspension?

    2016. All Rights Reserved. 21

  • SpeciesWhereOralUseOilVehiclesareAppropriate

    Dogs Cats Ferrets Turtles Lizards(speciesspecific)

    2016. All Rights Reserved. 22

  • SpeciesWhereOralAdministrationofOilsisNOTRecommended

    Birds Rabbits Gerbils Guineapigs Chinchillas Horses

    2016. All Rights Reserved. 23

  • OilVehiclesinAvianPatients

    Howcanwebestcompoundanoralprednisolonesuspensionforabird?Isfixedoiloktouseasabase?Wedonthavemanybirdsforpatients,so

    Imalittleunfamiliar.

    2016. All Rights Reserved. 24

  • OilVehiclesinAvianPatients Usually,aqueousbasedvehiclesarepreferredfor

    avianpatientsduetotheriskofaspiration Oilisnotanabsolutecontraindication,thereare

    exceptions Oilcanbeusedininstanceswhereaqueousisnotappropriate(i.e.

    stabilityissues)aslongastheowner/handlerofthebirdhasagoodrelationshipwiththebirdandcomfortleveltobeabletosafelyadministertheoil

    Therehasbeensuccessinthesepatientswithoilvehicles.Risk/benefitneedstobeassessedineachcase.Sometimesoilisabetteroptionthannotdoinganything.

    2016. All Rights Reserved. 25

  • PotassiumBromideinOil

    Clumpsveryeasily Notrecommended Aqueousformulasortreatsmuchbetteroption

    2016. All Rights Reserved. 26

  • BuprenorphineinOilforCats

    Canweputbuprenorphineinafixedoilforacatorwillitaffectabsorption?

    2016. All Rights Reserved. 27

  • OmeprazoleinOil

    Iseewehavemultipleformulasforomeprazoleinaqueousbase.Isthereanyproblemputtingitintoalmondoil?DoIneedtoworryaboutpHaswedowithanaqueousformula?

    2016. All Rights Reserved. 28

  • CombinationProducts

    2016. All Rights Reserved. 29

  • StabilityofRanitidineandOmeprazoleinCombinationProduct

    Ireceivedaquestionregardingthestabilityofafinalcompoundedproductifomeprazoleandranitidinearecombinedtogether.Thepersonhadheardthat,whencombined,theranitidinecausestheomeprazoletoquicklydegrade.Doyouhaveanyreferencesabouttheirstabilitytogether?

    2016. All Rights Reserved. 30

  • Absorption/BioavailabilityIssues

    2016. All Rights Reserved. 31

  • TransdermalCautions

    Antibiotics Thyroidornarrowtherapeuticindexdrugs Doesnotworkonreptiles

    2016. All Rights Reserved. 32

  • AbsorptionofCompoundedItraconazole

    Thereisagreatdealofconcernintheveterinarycommunityabouttheabsorptionofcompounded

    itraconazoleincats.Justcuriousiftheformulaisbeingalteredtoallowforbetterstabilityandabsorptionfor

    felines.

    2016. All Rights Reserved. 33

  • AbsorptionofCompoundedItraconazole

    Therehavebeenseveraltreatmentfailuresduetoimproperlycompoundeditraconazolesuspensionformulas

    Inappropriatedosingalsoleadstotreatmentfailures Thecommercialproductshaveagentsaddedtothemtoenhance

    bioavailability startingwithacommercialproductandthenswitchingtoacompoundedoptionusuallyresultsinatreatmentfailurebecauseofthedifferenceinbioavailabilityintheproducts

    HOWEVER

    2016. All Rights Reserved. 34

  • DifferentResults Severalveterinarycompoundingcolleagueshavereported

    treatmentsuccessinitiatingtherapywithitraconazoleinafixedoilsuspension

    Ithasbeenshownthatthelipidsinfattymealsmayenhancesolubilizationofinsolubledrugs

    DosingmustbedoneusingcapsuledosingrecommendationsperPlumbsVeterinaryDrugHandbook

    1. Hong JY, Kim J, Song YK, et al. A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. J Controlled Release, volume 110 (2006); 332-338.

    2016. All Rights Reserved. 35

  • AnotherOption Itraconazoleinaselfemulsifyingdrugdeliverysystem(SEDDS) SEDDSisamixtureofanappropriateoil,surfactant,andsometimes

    cosurfactants thatformanemulsionunderconditionssimilartowhatweseeintheGItract

    InHongsstudy,tocopherolacetate,poloxamer L64,anddiethylenemonoethyl etherwereusedduetotheirmaximumsolubilityofitraconazolecomparedtootheragents.Hydrochloricacidwasalsoaddedtoincreasesolubility.

    TheplasmaconcentrationoftheitraconazoleinSEDDSwasfoundtobehigherwhencomparedtothecapsuledosageform

    Thismaybeagoodoptionforveterinarypatients

    2016. All Rights Reserved. 36

  • Theophylline/Aminophylline

    ToSRortonotSR?Thatisthequestion GItransittimescanbeafactor Suspensions? Usingaminophyllineinplaceoftheophylline

    Transdermal yesorno??

    2016. All Rights Reserved. 37

  • Cyclosporine

    WereceivedaprescriptionforCyclosporine65mgcapsulestobecompoundedforadog.Inlookingattheformulas,allareoilfilledcapsules.Canwemaketheseaspowderfilledcapsules?

    Canwemakecyclosporineinafixedoilsuspension?

    2016. All Rights Reserved. 38

  • SucroseOctaacetate

    Iamusingpolyox withdiphenhydramine2%andthedogisabletoreachthesorewithhismouth,soheislickingandchewingit.IsthereaningredientthatIcanaddtomakeitmorebitterorwilltheyjusthavetouseacone?

    2016. All Rights Reserved. 39

  • OfficeUse Vet Currently,DQSA(503A)doesnotapplytoveterinarymedicine

    Officeusecompoundingisstilllegalintheveterinaryworld,aslongasstatelawsaysitislegal

    Donotcompoundfordispensingbytheveterinarian

    2016. All Rights Reserved. 40

  • Thankyou!

    Questions?

    2016. All Rights Reserved. 41

  • Dermanimal

    ChrisSimmons,RPhVPCreativeDevelopment

    2016. All Rights Reserved. 42

  • 2016. All Rights Reserved. 43

  • 2016. All Rights Reserved. 44

  • 2016. All Rights Reserved. 45

  • 2016. All Rights Reserved. 46

  • 2016. All Rights Reserved. 47

  • EpidermisComposition

    Keratinocytes Melanocytes Langerhanscells Merkelcells

    2016. All Rights Reserved. 48

  • HairFollicles

    Simplehairisasinglehair=horses /cattle Compoundhair=dogs,cats,sheep,andgoats Follicleshaveacentralhairsurroundedby315smallersecondaryhairsperpore

    Bornwithsimpleanddevelopintocompound

    2016. All Rights Reserved. 49

  • 2016. All Rights Reserved. 50

  • 2016. All Rights Reserved. 51

  • 2016. All Rights Reserved. 52

  • BaseSelection

    2016. All Rights Reserved. 53

  • Pyotraumatic Dermatitis

    Bacterialskininfectionsecondarytotrauma Pruritus,erythema,alopecia,exudates Chlorhexidinewashorshampoo

    Corticosteroids

    2016. All Rights Reserved. 54

  • 2016. All Rights Reserved. 55

  • Avenanthramide Tranilast

    2016. All Rights Reserved. 56

  • Tranilast

Recommended

View more >