building anew, biology

Growing is Forever, a film by Jesse Rosten

Building a new biology

watermelon eggplant carrot

banana corn broccoli

http://www.hhmi.org/biointeractive/dog-breeding

oil palm plantation

Genetically Engineered U.S. Domestic Product (2012)

http://www.nature.com/nbt/journal/v34/n3/abs/nbt.3491.html

http://en.wikipedia.org/wiki/Subtilisin

=

1x~20x

~200,000x

~1980, better soap cut US domestic hot water heating by up to 10% (or 100,000 bbl oil per day)

7

Graphic c/o "Synthetic Aesthetics,” MIT Press (2014)

http://www.apsnet.org/edcenter/intropp/lessons/viruses/Pages/PapayaRingspotvirus.aspx

Dennis Gonsalves

12Free .PDF of full briefing via DOI 1721.1/38455

http://dspace.mit.edu/handle/1721.1/38455

13http://ai.eecs.umich.edu/people/conway/VLSI/MIT78/MIT78.html

Lynn Conway’s VLSI course (1978)

14Free .PDF of full briefing via DOI 1721.1/38455

http://dspace.mit.edu/handle/1721.1/38455

15Graphic from "Synthetic Aesthetics" MIT Press (2014)

TAATACGACTCACTATAGGGAGA

Gene & Genome Constr. = #1 Tech. of 21st Ctry.

From abstract information to physical, living DNA designs.

2003: $4/bp2015: $0.04/bp2027: $0.0004/bp?

16

Luxo Jr., Pixar Animation Studios

http://www.wired.com/2013/04/how-pixar-used-moores-law-to-predict-the-future/

“When the group moved to California to become part of Lucasfilm, we got close to making a computer-animated movie again in the mid-1980s — this time about a monkey with godlike powers but a missing prefrontal cortex. We had a sponsor, a story treatment, and a marketing survey. We were prepared to make a screen test: Our hot young animator John Lasseter had sketched numerous studies of the hero monkey and had the sponsor salivating over a glass-dragon protagonist.

But when it came time to harden the deal and run the numbers for the contracts, I discovered to my dismay that computers were still too slow: The projected production cost was too high and the computation time way too long. We had to back out of the deal. This time, we [knew enough] to correctly apply Moore’s Law — [] we had to wait another five years to start making the first movie. And sure enough, five years later Disney approached us to make Toy Story.” — Alvy Ray Smith

http://en.wikipedia.org/wiki/Moore%27s_law

http://www.synthesis.cc/cgi-bin/mt/mt-search.cgi?blog_id=1&tag=Carlson%20Curves

DNA sequencing (read) & synthesis (write) are improving faster than silicon-based fab.

DNA sequencing (read) & synthesis (write) are improving faster than silicon-based fab.

OK GO, on treadmills https://www.youtube.com/watch?v=dTAAsCNK7RA

How should we organize ourselves to synthesize a first human genome? Should we? Stay tuned.

http://nas-sites.org/synbioroadmap/

Growing is Forever, a film by Jesse Rosten

Building anew, biology

http://www.livingplanetindex.org/projects?main_page_project=AboutTheIndex&home_flag=1

Past ~45 years, humans x 2, animals / 2

The living bridges of Cherrapunji, India are made from the roots of the Ficus elastica tree. (http://rootbridges.blogspot.com/)

Reproducing, growing, &

healing materials

~90 terawatts; pre-distributed

Massively functional

Living ramifications

Biology is nature’s nanotechnology

Take infectious & other diseases off the table

Provide for all of humanity

Stabilize & recover natural biodiversity

Enable a culture of citizenship

Understand life via building

http://rootbridges.blogspot.com

www.syntheticaesthetics.orgSISSEL TOLAASCHRISTINA AGAPAKIS

SISSEL TOLAASCHRISTINA AGAPAKIS

SISSEL TOLAASCHRISTINA AGAPAKIS www.syntheticaesthetics.org

You are what you eat!

We eat what we are...

SISSEL TOLAASCHRISTINA AGAPAKIS


Cambridge iGEM 2009

46

Photo by Roger Lancaster (http://www.flickr.com/photos/rogeral/5813079061/); educational fair use

The living bridges of Cherrapunji, India are made from the roots of the Ficus elastica tree. (http://rootbridges.blogspot.com/)

Reproducing, growing, &

healing materials

~90 terawatts; pre-distributed

Massively functional

Living ramifications

Biology is nature’s nanotechnology

Take infectious & other diseases off the table

Provide for all of humanity

Stabilize & recover natural biodiversity

Enable a culture of citizenship

Understand life via building

http://rootbridges.blogspot.com

building anew, biology

Engineering