bovine tb - bva parliamentary briefing

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Bovine TB BVA Parliamentary briefing Tuesday 27 October 2015 Sean Wensley BVSc MSc Grad DMS MRCVS BVA President John Blackwell BVSc MRCVS BVA Senior Vice-President

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Page 1: Bovine TB - BVA Parliamentary briefing

Bovine TBBVA Parliamentary briefing

Tuesday 27 October 2015

Sean Wensley BVSc MSc Grad DMS MRCVS BVA President

John Blackwell BVSc MRCVS

BVA Senior Vice-President

Page 2: Bovine TB - BVA Parliamentary briefing

Overview

• Bovine TB: what is the problem?• How bTB spreads• Controls:

• cattle• badgers• other species• Government approaches across the UK

• BVA position• Questions

Page 3: Bovine TB - BVA Parliamentary briefing

What is bovine TB?

• A complex infectious zoonotic disease of animals and humans

• Caused by the bacterium Mycobacterium bovis

• Maintenance hosts: cattle, badgers• Spillover hosts: various mammals inc humans,

deer, camelids, goats, pigs, dogs, cats

Page 4: Bovine TB - BVA Parliamentary briefing

• Direct effects on cattle • Production efficiency

• Indirect effects of disease• Business viability in face of control measures• Trade within and beyond the European

Union

What is the problem?

Page 5: Bovine TB - BVA Parliamentary briefing

bTB: the problem

All herds tested

3y Scot & Wal, 2y Eng

M bovis tuberculin replaces M tuberculosis

4 yr testing

FMD

120,000 herds 80,000 herds

Badgers Act 1973

Page 6: Bovine TB - BVA Parliamentary briefing

bTB: the problem

Page 7: Bovine TB - BVA Parliamentary briefing

bTB: the problem

Regions of England• High Risk Area (HRA)• Edge Area (EA)• Low Risk Area (LRA)

Page 8: Bovine TB - BVA Parliamentary briefing

How does bTB spread?The Randomised Badger Culling Trial report (2007) established:•that badgers “contribute significantly to the disease in cattle” and •that “cattle-to-cattle transmission is also very important in high incidence areas and is the main cause of disease spread to new areas”.

Page 9: Bovine TB - BVA Parliamentary briefing

How does bTB spread?

• Transmission• Cattle to cattle

• Badger to cattle (& vice versa)

• Translocation• Locally

• Greater distance

• Amplification

Spoligotype translocation

Post FMD 2001

Page 10: Bovine TB - BVA Parliamentary briefing

How does bTB spread?Critical control points

• Translocation• Transmission• Amplification

• Transmission• Amplification

Page 11: Bovine TB - BVA Parliamentary briefing

Controls in cattleTB Testing•Routine•Pre-movement•Post-movement

Risk based trading

Surveillance

Biosecurity

Farm Health

Planning

Page 12: Bovine TB - BVA Parliamentary briefing

Questions around TB testing

• Accuracy of the test• Frequency• Quality assurance

Page 13: Bovine TB - BVA Parliamentary briefing

Controls in cattle• Cattle vaccination?

• BCG (vaccine) does not fully protect any species• Differentiating Infected from Vaccinated Animals

(DIVA) test is not yet validated• Currently illegal in EU

European Commission (2013): “Possible EU rules on vaccinated animals… to enter intra-Union trade…. [2023]”

Page 14: Bovine TB - BVA Parliamentary briefing

Controls in badgers

• Biosecurity• Culling• Vaccination• Other?

Page 15: Bovine TB - BVA Parliamentary briefing

Badger control: Culling

• Randomised Badger Culling Trial (1998-2006)• Proactive culling of badgers reduces the incidence

of bTB in cattle herds• Net benefit 4.5 years post culling = 16% (Key

conclusions from a meeting of scientific experts held at Defra on 4th April 2011)

Page 16: Bovine TB - BVA Parliamentary briefing

Badger control: Vaccination• Injectable BCG• Not proven to protect from infection• Reduces the severity of the disease in infected

animals• Test to differentiate is unreliable • No evidence of impact on bTB in cattle• Oral vaccine?

Page 17: Bovine TB - BVA Parliamentary briefing

Badger control: OtherResearch:•Contraception•Oral vaccine•Humane whole sett culling methods•Trap- and sett-side diagnostics

Page 18: Bovine TB - BVA Parliamentary briefing

Control in other species

• Spillover hosts, eg:• Deer• Camelids (llamas and alpacas)• Goats• Pigs• Dogs• Cats

• Control measures inc biosecurity, testing, notification, and compulsory slaughter

Page 19: Bovine TB - BVA Parliamentary briefing

A comprehensive approachTB Testing•Routine•Pre-movement•Post-movement

Risk based trading

SurveillanceBiosecurity

Farm Health Planning

Vaccination

Culling•Targeted•Humane

Research•Cattle vaccine•Oral badger vaccine•Badger contraception•Improved diagnostics

Page 20: Bovine TB - BVA Parliamentary briefing

Policy approaches across the UK:England

Regionalisation• High Risk Area (HRA)• Edge Area (EA)• Low Risk Area (LRA)

Page 21: Bovine TB - BVA Parliamentary briefing

Policy approaches across the UK:England

Cattle controls•High risk = Annual herd testing•Edge = Annual herd testing•Low risk = Four yearly testing•High & edge = Routine pre-movement tests•Post-movement tests•Targeted use of interferon-gamma assay (IFN-γ)•Defra consultation on increased cattle controls (Oct 2015)

Badger controls•Two pilot cull areas (from 2013) to test method of culling•Independent Expert Group assessment of safety, efficacy and humaneness•New cull area in Dorset (from 2015)•Badger Vaccine Deployment Project to test deliverability

Page 22: Bovine TB - BVA Parliamentary briefing

Policy approaches across the UKScotland•Officially tuberculosis free

• Decision Sept 2009

• Implementation Feb 2010

•Risk-based testing

Wales•“Intensive Action Area”•Badger vaccination deployment•Cattle testing: Check Test Wales

NI•Separate epidemiological unit•Cattle testing•Modelling a “TVR” policy = Test and vaccinate or remove badgers

Page 23: Bovine TB - BVA Parliamentary briefing

BVA position: the ethics of cullingEthical review process•Ethically justifiable?•Scientific basis?•Feasible and deliverable?•Exit strategy?•Area of cull?•Cost benefit analysis?•Ecological impact?Ethical framework – the 3 Rs (reduce, refine, replace)

Targeted, effective and humane

Page 24: Bovine TB - BVA Parliamentary briefing

BVA position: Badger culling• We support badger culling as part of a comprehensive

strategy provided it is targeted, effective and humane

• We have withdrawn support for the use of controlled shooting BUT acknowledge there are different views with the veterinary profession

• We have called for the wider roll-out of culling using cage trapping and shooting only, in carefully selected areas

Page 25: Bovine TB - BVA Parliamentary briefing

BVA position: A comprehensive approach

TB Testing•Routine•Pre-movement•Post-movement

Risk based trading

SurveillanceBiosecurity

Farm Health Planning

Vaccination

Culling•Targeted•Humane

Research•Cattle vaccine•Oral badger vaccine•Badger contraception•Improved diagnostics