Blood Smear

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/animal/Circulatory/Human_blood_smear_HP_10x100_1_H.jpg

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/animal/Circulatory/Human_blood_smear_HP_10x100_2_H.jpg

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/animal/Circulatory/Human_blood_smear_HP_10x100_4_H.jpg

This peripheral blood smear from a patient with essential thrombocythemia shows increased numbers of platelets, including

some large forms. (H and E, 400x)

• Malaria

• Atypical, or reactive, lymphocytes

• Acanthocytes (red arrow) and schizocytes (black arrow) in a canine blood smear

• Keratocytes in a canine blood smear

Band neutrophil

Vacuolated monocyte

• Lymphocyte with azurophilic granules

• Hypersegmentation

• Toxic granulation

• Döhle body

• Platelets - finger-stick

• Giant platelet

• Nucleated Red Blood Cells

• Macrocytic Red Blood Cells Compared to Normal Red Blood Cells

• Promyelocyte

• Segmented Neutrophil, Metamyelocyte, Band

• Sickle Cell Anemia

• Pernicious Anemia

• Plasma cell

• Hairy cell

• Larger than average RBCs are macrocytic (left), while those smaller than average are microcytic (right).

• Pale cells (central pallor >1/3 dia) are referred to as hypochromic (right), while cells without central pallor are called hyperchromic (left).

• SCHISTOCYTES

• TARGETS

• OVALOCYTES

• STOMATOCYTES

• SPHEROCYTES

• ACANTHOCYTES

• BURR CELLS

• Elliptocytosis

• Tear Drop Cells

• Rouleaux Formation

Basophilic stippling

• Howell-Jolly Bodies

• Platelet Clumping

• Auer Rods

• With iron deficiency anemia, the MCV of the red blood cells is decreased, the zone of central pallor is increased, and the overall sizes and shapes of the RBC's are less uniform (increased anisocytosis and poikilocytosis ).

• Heinz bodies (red arrows) and nucleated red blood cells (purple arrows) in scattered erythrocytes of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).

• Spherocytes (red arrows) and nucleated red blood cells (purple arrows) in the blood smear of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).

• Can you identify the segmented neutrophil, band neutrophil, lymphocyte, monocyte, eosinophil, basophil, and platelet in this image?

• This is a picture of a blood smear as seen by a microscope.  The red cells are the smaller, more numerous round objects. There are two white cells in the middle (they are blue because they have been stained).

• Picture of bone marrow smear (control); Normal granulocytes and erythroblasts are evident.

• Acute lymphoid leukemia (ALL); There is a marked proliferation of small lymphoblasts.

• Acute myeloid leukemia (AML); There is a marked proliferation of lar

ge myeloblasts

• Chronic myeloid leukemia (CML); There is a marked proliferation of granulocytes at various stages of maturation.

• AML (M0)

• AML (M1)

• AML (M2)

• AML (M3)

• AML (M4)

• AML (M5)

• AML (M5) -alpha-naphthyl butyrate esterase and chloroacetate esterase stains

• AML (M6) -PAS stain

• AML (M6)

• AML (M7)

• Chronic myelocytic leukemia

• Chronic lymphocytic leukemia (CLL)

• Acute Lymphoblastic Leukemia (ALL)

• Acute lymphocytic leukemia (ALL)

• ALL-L1

• ALL-L2 　

• ALL-L3

thanks