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Biomedical Engineering Courses Description BME 212. Anatomy & Physiology (4 Cr. Hrs) two lectures per week and three hours of laboratory Prerequisite: Biology (BIO 101) Study of the basics of human anatomy and physiology including anatomical terminology, cells and tissues, body membranes, the skeletal system and muscular system. The nervous system, special senses, the cardiovascular system, ECG, the respiratory system, urinary system. BME 221. Biosignals and Biosystems (3 Cr. Hrs) two lectures per week Prerequisite: Electrical Circuits (ENRE 211), Applied Math for Eng I (MATH 201) Principles of biosignal processing. Linear time invariant systems; continuous time systems, application of Laplace and Fourier transforms to medicals linear systems; Discrete time systems; Z-transform; discrete Fourier series and fast Fourier transform; computer applications system function; frequency response and simulation in the frequency domain. BME 311. Health management Systems (3 Cr. Hrs) two lectures per week Prerequisite: Database Management Systems (CS 361) Data and dataflow in hospital, type of data, models of presentation, general ledger, cost accounting, evaluation techniques, budgeting and analysis, material management, inventory control. Introduction to management of health care information systems. Fundamentals, management of information systems, planning of projects, attendance of projects, system analysis, system evaluation, selection of systems, implementation of systems, finishing a project. BME 321. Medical Signal Processing (4 Cr. Hrs) two lectures per week and three hours of laboratory Prerequisite: Biosignals and Biosystems (BME 221) Acquisition and sampling of Biosignals; Shannon's Theorem, Fourier series and Fourier transform, power spectrum estimation, Wiener's Theorem, correlation techniques, computer aided ECG-processing in the frequency domain; signal averaging of EP,S; FIR Filter, IIR Filter, and Adaptive Filter ; Filter techniques. Students will use MatLab program as Processing Tools. BME 331. Biomechanics (4 Cr. Hrs) two lectures per week and three hours of laboratory Prerequisite: Statics & Dynamics (ME 211) Relationship between forces, moments, mass, and acceleration for human body and body segment motions. Centroids, center of mass, mass moment of inertia, and relative motion, mechanics of tissues, joints, and human movement. Basic anatomy and physiology of limb and joint defects, biomechanics, motion analysis, and current device designs. Application of mechanical engineering and biomaterial selection principles in the design of artificial limbs and joints. BME 332. Biomaterials (4 Cr. Hrs) two lectures per week and three hours of laboratory Prerequisite: Organic Chemistry (CPE 225) A course discusses various aspects pertaining to the selection, processing, testing (in vitro and in vivo) and performance of biomedical materials. The biocompatibility and surgical applicability of metallic, polymeric and ceramic implants and prosthetic devices are discussed. The physio-chemical interactions between implant material and physiological environment will be described. The use of biomaterials in maxillofacial, orthopedic, dental, ophthalmic and neuromuscular applications is presented. BME 421. Medical Instrumentation I (4 Cr. Hrs) two lectures per week and three hours of laboratory Prerequisite: Fundamental of Digital Electronics (ENRE 312), Anatomy and Physiology (BME 212) Analysis, and operation of transducers, sensors, and electrodes, for physiological systems; Instrumentation amplifiers. Principles of operation of selected devices: Blood Pressure, Temperature, Flow and Gas measurements devises, pulse oximeter, incubators, electrodes and insulin pump, Monitoring devises, electrocardiogram (ECG) devises, pacemaker and Defibrillation, ventilator and Anesthesia devices, Dialysis machine. Aspects of medical devices performance and accuracy, Patient safety. BME 422. Medical Instrumentation II (4 Cr. Hrs) two lectures per week and three hours of laboratory

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Biomedical Engineering Courses Description

BME 212. Anatomy & Physiology (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Biology (BIO 101)

Study of the basics of human anatomy and physiology including anatomical terminology, cells and tissues, body

membranes, the skeletal system and muscular system. The nervous system, special senses, the cardiovascular system,

ECG, the respiratory system, urinary system.

BME 221. Biosignals and Biosystems (3 Cr. Hrs) two lectures per week

Prerequisite: Electrical Circuits (ENRE 211), Applied Math for Eng I (MATH 201)

Principles of biosignal processing. Linear time invariant systems; continuous time systems, application of Laplace and

Fourier transforms to medicals linear systems; Discrete time systems; Z-transform; discrete Fourier series and fast Fourier

transform; computer applications system function; frequency response and simulation in the frequency domain.

BME 311. Health management Systems (3 Cr. Hrs) two lectures per week

Prerequisite: Database Management Systems (CS 361)

Data and dataflow in hospital, type of data, models of presentation, general ledger, cost accounting, evaluation techniques,

budgeting and analysis, material management, inventory control. Introduction to management of health care information

systems. Fundamentals, management of information systems, planning of projects, attendance of projects, system analysis,

system evaluation, selection of systems, implementation of systems, finishing a project.

BME 321. Medical Signal Processing (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Biosignals and Biosystems (BME 221)

Acquisition and sampling of Biosignals; Shannon's Theorem, Fourier series and Fourier transform, power spectrum

estimation, Wiener's Theorem, correlation techniques, computer aided ECG-processing in the frequency domain; signal

averaging of EP,S; FIR Filter, IIR Filter, and Adaptive Filter ; Filter techniques. Students will use MatLab program as

Processing Tools.

BME 331. Biomechanics (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Statics & Dynamics (ME 211)

Relationship between forces, moments, mass, and acceleration for human body and body segment motions. Centroids,

center of mass, mass moment of inertia, and relative motion, mechanics of tissues, joints, and human movement. Basic

anatomy and physiology of limb and joint defects, biomechanics, motion analysis, and current device designs. Application of

mechanical engineering and biomaterial selection principles in the design of artificial limbs and joints.

BME 332. Biomaterials (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Organic Chemistry (CPE 225)

A course discusses various aspects pertaining to the selection, processing, testing (in vitro and in vivo) and performance of

biomedical materials. The biocompatibility and surgical applicability of metallic, polymeric and ceramic implants and

prosthetic devices are discussed. The physio-chemical interactions between implant material and physiological environment

will be described. The use of biomaterials in maxillofacial, orthopedic, dental, ophthalmic and neuromuscular applications is

presented.

BME 421. Medical Instrumentation I (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Fundamental of Digital Electronics (ENRE 312), Anatomy and Physiology (BME 212)

Analysis, and operation of transducers, sensors, and electrodes, for physiological systems; Instrumentation amplifiers.

Principles of operation of selected devices: Blood Pressure, Temperature, Flow and Gas measurements devises, pulse

oximeter, incubators, electrodes and insulin pump, Monitoring devises, electrocardiogram (ECG) devises, pacemaker and

Defibrillation, ventilator and Anesthesia devices, Dialysis machine. Aspects of medical devices performance and accuracy,

Patient safety.

BME 422. Medical Instrumentation II (4 Cr. Hrs) two lectures per week and three hours of laboratory

Prerequisite: Medical Instrumentation I (BME 421)

Theory and principles of biosensor design and application in medicine and biology. Analysis and selection of physical,

electrical, mechanical, thermal transduction mechanisms, which form the basis of the biosensor design. Principles and

fundamental properties of transducers (dynamics, linearity, hysteresis, and frequency range). transducer interfacing and

signal conditioning, material biocompatibility, and packing. Selected examples: micro fluidics, bioelectronics, pressure

sensors, temperature sensors and electrochemical sensors.

BME 423. Magnetic Resonance Imaging (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

This course will first introduce the basic physics of MRI, including magnetic moments and resonance, nuclear spin

interactions with applied magnetic fields, and magnetic relaxation. The second portion of the course will discuss basic

concepts of image formation, including radiofrequency pulse excitation, magnetic field gradients, imaging equation, Fourier

Transform, and two-dimensional spatial encoding. The final portion of the course will introduce practical imaging methods

and applications, such as image artifacts, fast imaging methods, signal-to-noise, contrast-to-noise, resolution, MR imaging of

heart and blood vessels, and MR imaging of the neural system.

BME 424. Fundamentals of X-Ray Modalities (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Physics and fundamentals of x-rays, conventional x-ray modality, Computerized Tomography CT modality. Principles of 3D

reconstruction from projections in medicine. The mathematics of reconstruction from projections. Application of x-ray's

modalities in human body scanning.

BME 425. Introduction to Ultrasound Technique (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Physics and fundamentals of Ultrasound. Propagation of ultrasound in heterogeneous media such as tissue, Ultrasound

Imaging principles and basic of tissue characterization. Ultrasound Modality including details of A- and B- mode scanners.

Simple tissue models based on ultrasound wave absorption and scattering. Ultrasound transducer models, advantages and

disadvantages of various transducer configurations. The principles of acoustic output measurements and instrumentation

requirements. Electrical and biological effects of ultrasound diagnostics algorithms.

BME 426. Medical Image Processing (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

The human visual system, imaging techniques, image quantization, grey value transformations, local filter, 2D Fourier

transform, gradient operators, morphological filter, image enhancement, encoding, restoration, and reconstruction, object

segmentation , textures, edge detection, thinning algorithms features for classification Image Compression and

watermarking. Projects on different medical images are compulsory.

BME 427. Biosignals processing (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Signal Processing (BME 321)

This course covers biomedical signal characteristics, biomedical systems, and models, applications of Fourier transform

wavelet transforms, and joint-time frequency analysis of biomedical signals. Systems studies include ultrasounds, ECG’s

CAT scans, MRI’s, X-rays, and others.

BME 428. Engineering Optics for Medical Application (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Introductory overview of optical phenomena and the optical properties of biological tissue. Fundamentals of optical systems

design, integration and analysis used in biomedical optics. Design components: light sources, lenses, mirrors, dispersion

elements optical fiber, detectors. Systems integration: radiometry and interferometer. Optical system analysis: resolution,

modulation transfer function, deconvolution, tissue optics and noise. Optical imaging applications in biology and medicine:

reflection, refraction, interference, diffraction, polarization, light scattering and fluorescence, and their application in

biomedical imaging and microscopy.

BME 429. Photomedicine (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Physics and fundamentals of LASER Optical and engineering based systems (laser-based) in diagnosis, treating diseases,

manipulation of cells and cell function Medical Devices using LASER.

BME 431. Principles of Tissues Engineering (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332) and Biomechanics (BME 331)

The selection, processing, testing and performance of materials used in biomedical application with special emphasis upon

tissues engineering. Topics include material selection and processing, mechanism and kinetics of materials degradation,

cell-materials interaction and interface; effects of construct architectures on tissue growth; and transport through engineered

tissues. Examples of engineering tissues for replacing cartilage, bone, tendons, ligaments, skin and liver will be presented.

BME 432. Advanced Topics in Tissue Engineering (3 Cr. Hrs) two lectures per week

Prerequisite: Principles of Tissues Engineering (BME 431)

General principles of tissue engineering includes aspects of cell isolation and propagation; matrix selection; construct

creation, manipulation, and implementation, and evaluation of resulting repairs. Applications: skin replacement, cartilage

tissue repair, bone tissue engineering, nerve regeneration, corneal and retinal transplants, ligaments and tendons, blood.

Substitutes artificial pancreas, artificial lever, tissue integration with prosthetics, vascular grafts, and cell encapsulation

angiogenesis.

BME 433. Bone Tissue Regeneration (3 Cr. Hrs) two lectures per week

Prerequisite: Biomechanics (BME 331)

Description of micro- and macro-anatomy of bone, its embryology, and would healing, traditional bone grafting materials. In

vitro methods and animal wound models for designing and developing bone regeneration therapies.

BME 434. Polymeric Biomaterials (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Basics and applied concepts of polymers as biomaterials. Fundamental synthetic mechanism of polymers and their physical

and chemical properties. Biodegradation mechanism, mechanical properties and surface chemistry of polymeric materials.

Cellular interactions with various surface and immunological responses. Application of biomaterials include tissue

engineering and artificial organs.

BME 435. Advanced Cardiovascular Biomechanics (3 Cr. Hrs) two lectures per week

Prerequisite: Biomechanics (BME 331)

The dynamics of the heart and blood vessels. Pulsatile blood flow, microcirculation, and muscle mechanics. Modeling of

boundary value problems in cardiovascular engineering. Tissue Engineering in cardiovascular application: Artificial Heart

and Blood.

BME 436. Biomaterials Tissue Interaction (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Examines the principle of materials science and cell biology underlying the design of medical device, artificial organs and

scaffolds for tissue engineering. Molecular and cellular interaction with biomaterials are analyzed in terms of cellular

processes such as matrix synthesize, degradation and contraction. Principles of wound healing and tissue remodeling are

used to study biological responses to implanted materials and devices. Additionally, this course examine criteria for restoring

physiological function of tissue and organs and investigate strategies to design implants and prostheses based on control

biomaterial-tissue interactions.

BME 437. Tissue Mechanics (3 Cr. Hrs) two lectures per week

Prerequisites: Biomechanics (BME 331)

Advanced techniques for the characterization of the structure and function of hard and soft tissues and their relationship to

physiologic processes. Solid mechanics of prominent musculoskeletal and cardiovascular tissues. Their normal and

pathological behaviors (stiffness, strength, relaxation, creep, adaptive remodeling, etc) in response to physiologic loading

will be examined and quantified. Application includes: tissue injury, wound healing, the effect of pathological conditions upon

tissue properties and design of medical device and prostheses.

BME 438. Composite with Biomedical and Materials (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Introduction to fiber/ particulates reinforced, engineered and biologic materials. Focus on elastic descriptions and application

of composite materials. The development of constitutive equation that defines the mechanical behavior of a number of

applications of emphasized, including: biomaterial, tissue, and materials science.

BME 439. Biomaterials in the design of Medical Devices (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Addresses a unique rule of biomaterial in medical device design and the use of emerging biomaterials technology in medical

device. The need to understand design requirements of medical devices based on safety and efficacy will be addressed. An

expected device failure due to synergistic interactions from chronic loading, aqueous environments and biologic interactions.

Testing methodologies to assess accelerated effects of loading in physiologic-like environments. Evaluate biomaterials and

their properties as related to design and reliability of medical devices.

BME 461. Introduction to Nanomaterials Science and Engineering (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Nanotechnology involves behavior and control of materials and processes at the atomic and molecular levels. This

interdisciplinary course introduces the theoretical basis, synthetic processes and experimental techniques for nanomaterials.

Introduction to nanostructures, microstructures, macrostructures and functional components of hard and soft tissue as

applied to implantable materials, devices and pharmaceutical modalities.

BME 462. BioMEMS (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Micro and nanosystem used in advanced analytical techniques for microfluidic devices, implantable chips, non invasive

biomedical sensors, DNA chips and microelectronic array system. Biomedical sensors and actuators. bioMEMS active

ultrasonic transducers for medical imaging, for micro- valves and for implantable medication delivery systems are studied.

BME 463. Biochemical Sensors (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Biosensors which monitor levels of blood electrolytes for real-time patient management are surveyed in this course.

Fundamental principles underlying the transducers that convert chemical activity into electrical or optical signals are studied

in depth. Sensitive and selective biological membranes based on ion, enzyme, and immune-reactions. Sensor stability and

response time. Other processes involved in the operation of the sensors such as membrane diffusion, capillary transport and

cell separation are also covered. Devices for measuring blood gases, electrolytes, hemoglobin, glucose, PH, drugs and

other bioactive compounds are also presented.

BME 464. Chemical and Optical Sensors (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Theory, design, and applications of chemical and optical sensors used in medical diagnosis, patient monitoring, and

Laboratory devices. Electrochemical and optical sensors.

BME 465. MEMS Design (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Use of MEMS in biotechnology, instrumentation, robotics, manufacturing and other applications. Synthesize and design high

performance MEMS that satisfy the requirements and specifications imposed. Integrated approaches applied to design and

optimize MEMS including: integrate microelectromechanical motion devices, ICs, and micro sensors. Recent advances in

biomedical applications of MSMS. Course will require a design using CAD tool for a biomedical MEMS-based micro

integrated system.

BME 466. MEMS System Evaluation (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

General evaluation methodologies. Evaluation of MEMS, micro system and microelectromechanical motion devices utilizing

MEMS testing and characterization. Performance evaluation matrices, comprehensive performance analysis and

functionality. Applications of advanced software and hardware in MEMS evaluation.

BME 467. CAD/CAM (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Selected topics in mechanical design, computer aided engineering computer aided design, computer aided manufacturing

and computer integrated manufacturing. Software Design: Mechanical desktop. Computerized Numerical control CNC

machine and g-gode programming.

BME 468. Micro/Nano Fabrication Techniques (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Overview of semiconductors materials. Semiconductors devices application actuators control system and sensors.

Instruction and hands-on semiconductor process in clean-room environment, including two sided wet and dry lithography for

microelectronics, micro sensors and MEMS. Micro fabrication principles and elements, epitaxial growth, oxidation, thin film

deposition. Lithography, etching, doping and LIGA micromachining and process integration.

BME 469. Advanced Topics in Bio MEMS (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation II (BME 422)

Genome sequencing, gene expression measurements and applications: programmable DNA/ molecular for sequencing and

diagnostics, biomaterials and self- assembled nanostruction for biosensors and drug delivery.

BME 499. Practical Training (12 Cr. Hrs) six months in Germany

Prerequisite: Complete ? credits and Department approval

Students will practice their knowledge for about 6 months in various hospitals, labs and associations. It is understood that

specialized training in the workplace for graduates to fulfill more advanced requirements of the job. Their educational training

however, should provide them with a strong knowledge and skill background that serves as a foundation for easy transition

into specialized applications encountered in the workplace.

BME 511. Cell Matrix Mechanics (3 Cr. Hrs) two lectures per week

Prerequisite: None

Mechanical properties and behavior of the cell, cellular structures, and the directs cellular environment. Mechanically

relevant structure of the cell and the extracellular matrix. Visualization and manipulation of cells with Atomic Force

Microcopy and Confocal Laser Scanning Microscopy. Mechanical properties of cell structures and extracellular matrix

components. Mathematical models to describe the (dynamics) mechanical behavior of cells ranging from tensegrity models

of the cytoskeleton to multi-level FE models of groups of cells in their extracellular environment. Mechanotransduction and

gene expression in response to mechanical stress. The major hypotheses on mechanotransduction pathways in the cell are

discussed.

BME 521. Reliability and Security of Medical Devices (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Identification and verification reliability element indices and systems for various model types partition period to the failure

and between failures with respect on medical instrument specifies, warranty of patient’s safety and medical device service

Reliability exams, statistic acceptance of reliability, preventive maintenances systems of reliability operation exams.

BME 522. System Safety (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Physiological effects of electricity Inductive methods for analyzing systems to recognize, evaluate, and control hazards.

Techniques include preliminary hazard analysis, failure mode and effects analysis, protection and equipment design. Safety

analyzer and lest of devices for safety.

BME 523. Fiber Optics (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Introduction to fiber optics, review of communication systems and light wave fundamental. The study of dielectric

waveguides and optical fibers, light- emitting diodes(LEDs) laser diodes and photo detectors, discussion of optical fiber

communication systems with special attention to noise sources in optical receivers, lit error rate and power budget.

BME 524. Biorobotics (3 Cr. Hrs) two lectures per week

Prerequisite: Statics & Dynamics (ME 211)

Topics include biomimetic design (why nature and humans design differently), sensors (touch, stereo and position),

actuators (muscles, smart materials), and intelligent (neural and computer controlled) systems. Also it will cover the

application of robotics medicine.

BME 525. Biological Basis of imaging (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Study Physical properties of tissues that determine the nature of the information obtainable by Imaging Technique.

Establishing a strong connection between the methods of imaging and the underlying biological processes that give rise to

image information is the overall goal of this class. This course provides the background by which students will learn not only

what biological properties affect the signals used to construct images but also how various imaging approaches may be

used to understand biological processes.

BME 526. Quantitative Functional Imaging (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

This course emphasizes the technical aspects of making quantitative measurements of structure and function using different

imaging methods, including special imaging methods as well as approaches to image analysis algorithms, and the use of

modeling or data analytic techniques for assessing function.

BME 527. Laser/Tissue Interaction (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

The optical behavior of random media in interaction with laser irradiation. Approximate transport equation methods to predict

the absorption and scattering parameters of laser light inside tissue., measuring absorption spectra of tissue/tissue

phantoms, making tissue phantoms, determination of optical properties of different tissues, techniques of temperature

distribution measurements. Port-wine stain treatment; cancer treatment by photo chemotherapy, cardiovascular applications.

Computer simulations of light propagation in tissue.

BME 528. Introduction to Ionizing Radiation (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Covering the basic principles of radiation and the interaction of radiation with matter, with particular attention given to

radiation detection and measurement. Discusses natural and man-made radiation sources, energy deposition and dose

calculations, various physical, chemical, and biological processes and effects of radiation with examples of their uses, and

principles of radiation protection. Throughout the course emphasis is placed on the underlying physics and the technical

issues that impact image quality.

BME 529. Fundamentals of Computer Tomography (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

The development of Computed Tomography, X-ray detectors, X-ray linear attenuation coefficient, Type of Scanning (Fan

Beam Fixed and Rotating detector, Scanning electron beam, spiral scanning) , Data acquisition, Reconstruction principles,

artifact and reconstruction error, patient dose consideration.

BME 531. Human Anthrometric and Physical Measurements (3 Cr. Hrs) two lectures per week and three hours of

laboratory

Perquisite: Biomechanics (BME 331)

Engineering aspects of the human Body Parts Measure. Find patterns and symmetry in human body. Applied these aspects

to Biomechanics Science and Biomechanics design. Used international standard Measurement table of the human Body.

BME 532. Occupational Biomechanics (3 Cr. Hrs) two lectures per week

Perquisite: Biomechanics (BME 331)

Advanced study of biomechanical and physiological modeling and measurement techniques useful in the study and

mitigation of physical stressors in the industrial workplace and study cumulative trauma disorders and slip fall prevention

applied to the organization.

BME 533. Surgery for Engineers (3 Cr. Hrs) two lectures per week

Prerequisite: Medical Instrumentation I (BME 421)

Fundamental skills and principles of surgery devices. Operating rooms design and sterilization. Computer assisted surgery

technologies, including surgical navigation, image guidance and robotic surgery.

BME 534. Biomechanics of Hard Tissues (3 Cr. Hrs) two lectures per week

Prerequisite: Biomechanics (BME 331)

Structure property relationships for mineralized connective tissues of human body. Discussion centers on various types of

bone (e.g lamellar, woven) and teeth with an emphasis on modeling for biomechanical behavior, both in vitro and in vivo.

Topics include elastic models for born (isotropic and anisotropic), theories of yielding and fatigue, strength properties,

composite and hierarchical models, and models of bone remodeling/modeling.

BME 535. Artificial Organs (3 Cr. Hrs) two lectures per week

Prerequisite: Principles of Tissues Engineering (BME 431)

Engineering aspects of artificial organ design. Artificial kidney, lungs, hearts, eyes, livers, and pancreases. Extracorporeal

cellular immunotherapy.

BME 536. Drug Delivery (3 Cr. Hrs) two lectures per week

Prerequisite: none

Engineering principle and biological considerations in designing drug delivery systems for medicals uses. The concept of

biocompatibility and its implication in formulation controlled release devises are illustrated. Emphasis on the use of

biodegradation materials to design drug delivery systems for site-specific applications.

BME 537. Theoretical & Applied Polymer Science (3 Cr. Hrs) two lectures per week

Prerequisite: None

An advanced course in materials science and engineering dealing specifically with the structure and properties of polymers.

Particular attention paid to recent developments in the processing and use of modern plastics and fibers. Product design

considered in terms of polymer structures, processing techniques, and properties.

BME 538. Transport Phenomena in Cells and Organs (3 Cr. Hrs) two lectures per week

Perquisite: Fluid Mechanics (ME 222), Biochemistry (CPE 326)

Applications of the principles of mass and momentum transport to the analysis of selected processes of biomedical and

biotechnological interest. Emphasis on the development and critical analysis of models of the particular transport process.

Topics include: reaction-diffusion processes, transport in natural and artificial membranes, dynamics of blood flow,

pharmacokinetics, receptor-mediated processes and macromolecular transport, normal and neoplastic tissue.

BME 539. Biotechnology and Bioprocess Engineering (3 Cr. Hrs) two lectures per week

Prerequisite: None

Introduction to the engineering principles of bioprocess engineering. Topics include: introduction to cellular and protein

structure and function, modeling of enzyme kinetics, DNA transcription, metabolic pathways, cell and microbial growth and

product formation, bioprocess operation, scale-up, and design. Class includes a design project.

BME 552. Tenders & Technical Specification (3 Cr. Hrs) two lectures per week

Prerequisite: None

Students will able to write Tenders and Technical Specification for medical device (the correct level of detail, Information find

quickly and efficiently), Bid writing(giving tight deadline).

BME 553. Biomedical Ethics and Safety (3 Cr. Hrs) two lectures per week

Prerequisite: None

Introduces the wide spectrum of ethical, regulatory, and legal issues facing health care practitioners and health- related

research workers. Helps students become aware of the ethical and legal issues involved in their work. Helps students

understand how legal and ethical decisions should be made in health-related matters, as well as what sources of help and

guidance are available.

BME 561. Neuroengineering (3 Cr. Hrs) two lectures per week

Prerequisite: Anatomy and Physiology(BME 212)

Introduces the theory of neural signaling. Students will learn the fundamental theory of cellular potentials and chemical

signaling, the Hodgkin Huxeley description of action potential generation, circuit representations of neurons and be able to

derive and integrate equations describing the circuit as well as design computer models.

BME 562. Nanomechanics of Materials and Biomaterials (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

Latest scientific developments and discoveries in the field of nanomechanics, i.e. the deformation of extremely tiny (10-9

meters) areas of synthetic and biological materials. Lectures include a description of normal and lateral forces at the atomic

scale, atomistic aspects of adhesion, nanoindentation, molecular details of fracture, chemical force microscopy, elasticity of

individual macromolecular chains, intermolecular interactions in polymers, dynamic force spectroscopy, biomolecular bond

strength measurements, and molecular motors.

BME 563. Prosthetics and Orthotics (3 Cr. Hrs) two lectures per week

Prerequisite: Biomaterials (BME 332)

This is an introductory course in the designing and evaluation of prosthetics (artificial limbs), and orthotics (braces and

splints).Biocompatibility of materials used in Orthopedic and dental applications.

BME 564. Movement Biomechanics and Rehabilitation (3 Cr. Hrs) two lectures per week

Prerequisite: Biomechanics (BME 331)

Biomechanics for the design and evaluation of artificial devices intended to restore or improve movement lost due to injury

or disease. Measurement technique in movement biomechanics, including motion analysis, electromyography, and gait

analysis. Design and use of upper and lower limb prostheses. Principle of neuroprostheses with applications to paralyzed

upper and lower extremities.

BME 565. Biomechanics of Soft Tissues (3 Cr. Hrs) two lectures per week

Prerequisite: Biomechanics (BME 331)

Applications of continuum mechanics in modeling the biomechanical behavior of nonmineralized tissues such as tendons,

ligaments, skin, cartilage, blood, vessels , ets.

Topics include structure of collagen, elastin proteoglycans, and other tissue components, nonlinear elastic models (including

Fung’s pseudoelasticity approach and strain energy functions), linear viscoelasticity, Fung’s quasilinear viscoelasticity,

herhditray formulation of constitutive equations, and introduction to mixture theory.

BME 598. BME 599.Graduation Project I and II (3 Cr. Hrs each) two semesters

Prerequisite: Department Approval

Biomedical students discuss a medical problem in their specialized field and try to provide solution to it either hardware or

software or both. Also students are able to develop or design new simple medical devices.