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Bibliography Gerald M. Edelman Books 1. Edelman, G.M. and Mountcastle, V.B. (1978) The Mindful Brain: Cortical Organization

and the Group Selective Theory of Higher Brain Function. MIT Press, Cambridge. 2. Edelman, G.M. (1987) Neural Darwinism: The Theory of Neuronal Group Selection.

Basic Books, New York. 3. Edelman, G.M. (1988) Topobiology: An Introduction to Molecular Embryology. Basic

Books, New York. 4. Edelman, G.M. (1989) The Remembered Present: A Biological Theory of

Consciousness. Basic Books, New York. 5. Edelman, G.M. (1992) Bright Air, Brilliant Fire: On the Matter of the Mind.

Basic Books, New York. 6. Edelman, G.M. and Tononi, G. (2000) A Universe of Consciousness: How

Matter Becomes Imagination. Basic Books, New York. 7. Edelman, G.M. (2004) Wider Than The Sky: The Phenomenal Gift of

Consciousness. Yale University Press, New Haven, Connecticuit.

Books Edited 1. Edelman, G.M., ed. (1974) Cellular Selection and Regulation in the Immune

Response. Raven Press, New York. 2. Edelman, G.M., Gall, W.E., Cowan W.M., eds. (1984) Dynamic Aspects of Neo-

Cortical Function. Wiley, New York. 3. Edelman, G.M., Gall, W.E., Cowan, W.M., eds. (1985) Molecular Bases of Neural

Development. Wiley, New York. 4. Edelman, G.M., Thiery, J.-P., eds. (1985) The Cell in Contact: Adhesions and

Junctions as Morphogenetic Determinants. Wiley, New York. 5. Edelman, G.M., ed. (1985) Molecular Determinants of Animal Form, UCLA Symposia

on Molecular and Cellular Biology, New Series, Vol. 31 Alan R. Liss, New York. 6. Edelman, G.M., Gall, W.E., Cowan, W.M., eds. (1987) Synaptic Function. Wiley, New

York. 7. Edelman, G.M., Gall, W.E., Cowan, W.M. eds. (1988) Auditory Function: Neurological

Bases of Hearing, John Wiley and Sons, New York. 8. Edelman, G.M., Cunningham, B.A., and Thiery, J.-P., eds. (1989) Morphoregulatory

Molecules. John Wiley and Sons, New York.

Gerald M. Edelman Bibliography 9. Edelman, G.M., Gall, W.E., and Cowan, W.M., eds. (1989) Signal and Sense: Local

and Global Order in Perceptual Maps, John Wiley and Sons, New York. 10. Edelman, G.M. and Changeux, J-P. (2000) The Brain. Transaction Publishers,

London.

Articles 1. Edelman, G.M., Kunkel, H.G., and Franklin, E.C. (1958) Interaction of the rheumatoid

factor with antigen-antibody complexes and aggregated gamma globulin. J. Exp. Med. 108:105-120.

2. Franklin, E.C., Edelman, G.M., and Kunkel, H.G. (1959) Studies on high-molecular

weight γ-globulins and their complexes in rheumatoid arthritis. In Immunity and Virus Infection, V.A. Najjar, ed. pp. 92-99, Wiley, New York.

3. Edelman, G.M. (1959) Dissociation of γ-globulin. J. Am. Chem. Soc. 81:3155. 4. Edelman, G.M., Heremans, J.F., Heremans, M.-Th., and Kunkel, H.G. (1960)

Immunological studies of human γ-globulin. J. Exp. Med. 112:203-223. 5. Edelman, G.M. and Poulik, M.D. (1961) Studies on structural units of the globulins. J.

Exp. Med. 113:861-884. 6. Poulik, M.D. and Edelman, G.M. (1961) Comparison of reduced alkylated derivatives of

some myeloma globulins and Bence-Jones proteins. Nature 191:1274-1276. 7. Edelman, G.M., Benacerraf, B., Ovary, Z., and Poulik, M.D. (1961) Structural differences

among antibodies of different specificities. Proc. Natl. Acad. Sci. USA 47:1751-1758.

8. Edelman, G.M. and Benacerraf, B. (1962) On structural and functional relations between

antibodies and proteins of the gamma-system. Proc. Natl. Acad. Sci. USA 48:1035-1042.

9. Edelman, G.M. and Gally, J.A. (1962) The nature of Bence-Jones proteins. J. Exp. Med.

116:207-227. 10. Gally, J.A. and Edelman, G.M. (1962) The effect of temperature on the fluorescence of

some aromatic amino acids and proteins. Biochim. Biophys. Acta 60:499-509. 11. Olins, D.E. and Edelman, G.M. (1962) The antigenic structure of the polypeptide

chains of human γ-globulin. J. Exp. Med. 116:635-651.

Gerald M. Edelman Bibliography 12. Eisenberg, L., Rosen, P., and Edelman, G.M. (1962) AGC amplifier to correct for

effects of light source variations in spectrofluorometric measurements. Rev. Sci. Instr. 33:1435-1440.

13. Edelman, G.M. (1962) Structural relations between normal and pathologic γ-globulins.

Ann. N.Y. Acad. Sci. 101:246-253. 14. Berggard, I. and Edelman, G.M. (1963) Normal counterparts to Bence-Jones proteins:

free L polypeptide chains of human γ-globulin. Proc. Natl. Acad. Sci. USA 49:330-337.

15. Schwartz, J.H. and Edelman, G.M. (1963) Comparisons of Bence-Jones proteins and L

polypeptide chains of myeloma globulins after hydrolysis with trypsin. J. Exp. Med. 118:41-54.

16. Edelman, G.M., Benacerraf, B., and Ovary, Z. (1963) Structure and specificity of

guinea pig 7S antibodies. J. Exp. Med. 118:229-244. 17. Edelman, G.M., Olins, D.E., Gally, J.A., and Zinder, N.D. (1963) Reconstitution of

immunologic activity by interaction of polypeptide chains of antibodies. Proc. Natl. Acad. Sci. USA 50:753-761.

18. Edelman, G.M. (1963) Unresolved problems in the analysis of the structure of

antibodies. In Immunopathology, Third International Symposium, T. Zacharia and S.S. Breese, eds. pp. 57-67, Schwabe and Co., Basel, Switzerland.

19. Gally, J.A. and Edelman, G.M. (1964) Effects of conformation and environment on the

fluorescence of proteins and polypeptides. In Quantum Aspects of Polypeptides and Polynucleotides, Biopolymers Symposia No. 1, M. Weissbluth, ed., pp. 367-381, Wiley, New York.

20. Edelman, G.M. and Kabat, E.A. (1964) Studies on human antibodies. I. Starch gel

electrophoresis of the dissociated polypeptide chains. J. Exp. Med. 119:443-452. 21. Olins, D.E. and Edelman, G.M. (1964) Reconstitution of 7S molecules from L and H

polypeptide chains of antibodies and γ-globulins. J. Exp. Med. 119:789-815. 22. Gally, J.A. and Edelman, G.M. (1964) Protein-protein interactions among L polypeptide

chains of Bence-Jones proteins and human γ-globulins. J. Exp. Med. 119:817-836. 23. Edelman, G.M. and Gally, J.A. (1964) A model for the 7S antibody molecule. Proc.

Natl. Acad. Sci. USA 51:846-853. 24. Fougereau, M., Olins, D.E., and Edelman, G.M. (1964) Reconstitution of antiphage

antibodies from L and H polypeptide chains and the formation of interspecies molecular hybrids. J. Exp. Med. 120:349-358.

Gerald M. Edelman Bibliography 25. Fougereau, M. and Edelman, G.M. (1964) Resemblance of the gross arrange ment of

polypeptide chains in reconstituted and native γ-globulins. Biochemistry 3:1120-1126.

26. Edelman, G.M. (1964) Formation of active 7S antibody molecules by reassociation of L

and H polypeptide chains. In Molecular and Cellular Basis of Antibody Formation, Proceedings of a Symposium Held in Prague, J. Sterzl, ed., pp. 113-123, Academic Press, New York.

27. Fougereau, M. and Edelman, G.M. (1965) Corroboration of recent models of the γG

immunoglobulin molecule. J. Exp. Med. 121:373-394. 28. Gally, J.A. and Edelman, G.M. (1965) Physicochemical properties of Bence-Jones

proteins in the form of L-chain dimers. Biochim. Biophys. Acta. 94:175-182. 29. Rosen, P. and Edelman, G.M. (1965) Versatile and stable recording spectro-

fluorometer for the measurement of corrected spectra. Rev. Sci. Instr. 36:809-815. 30. Marchalonis, J. and Edelman, G.M. (1965) Phylogenetic origins of antibody structure. I.

Multichain structure of immunoglobulins in the smooth dogfish (Mustelus canis). J. Exp. Med. 122:601-618.

31. Gotschlich, E.C. and Edelman, G.M. (1965) C-reactive protein: A molecule composed

of subunits. Proc. Natl. Acad. Sci. USA 54:558-566. 32. Edelman, G.M. (1966) Molecular mechanisms of the immune response. In Molecular

Architecture in Cell Physiology, T. Hayashi and A. Szent-Gyorgyi, eds., pp. 99-121, Prentice Hall, Englewood Cliffs, New Jersey.

33. McClure, W.O. and Edelman, G.M. (1966) Fluorescent probes for conformational

states of proteins. I. Mechanism of fluorescence of 2-p-toluidinylnaphthalene-6-sulfonate, a hydrophobic probe. Biochemistry 5:1908-1919.

34. Marchalonis, J. and Edelman, G.M. (1966) Phylogenetic origins of antibody structure.

II. Immunoglobulins in the primary immune response of the bullfrog, Rana catesbiana. J. Exp. Med. 124:901-913.

35. Marchalonis, J. and Edelman, G.M. (1966) Polypeptide chains of immunoglobulins

from the smooth dogfish (Mustelus canis). Science 154:1567-1568. 36. Edelman, G.M. and Gally, J.A. (1967) Somatic recombination of duplicated genes: A

hypothesis on the origin of antibody diversity. Proc. Natl. Acad. Sci. USA 57:353-358.

Gerald M. Edelman Bibliography 37. McClure, W.O. and Edelman, G.M. (1967) Fluorescent probes for conformational

states of proteins. II. The binding of 2-p-toluidinylnaphthalene-6-sulfonate to a α-chymotrypsin. Biochemistry 6:559-566.

38. McClure, W.O. and Edelman, G.M. (1967) Fluorescent probes for conformational

states of proteins. III. The activation of chymotrypsinogen. Biochemistry 6:567-572.

39. Weltman, J.K. and Edelman, G.M. (1967) Fluorescence polarization of human yG-

immunoglobulins. Biochemistry 6:1437-1447. 40. Gotschlich, E.C. and Edelman, G.M. (1967) Binding properties and specificity of C-

reactive protein. Proc. Natl. Acad. Sci. USA 57:706-712. 41. Waxdal, M.J., W.J. Konigsberg, and G.M. Edelman. (1967) The structure of a human

yG-immunoglobulin. In Cold Spring Harbor Symposium on Quant. Biol. 32:53-63. 42. Edelman, G.M. (1967) Studies on the primary and tertiary structure of yG-

immunoglobulin. Nobel Symposium 3:89-108. 43. Edelman, G.M. (1967) Antibody structure and diversity: Implications for theories of

antibody synthesis. In The Neurosciences: A Study Program, G.C. Quarton, T. Melnechuk, and F.O. Schmitt, eds., pp. 188-200, Rockefeller University Press, New York.

44. Edelman, G.M. and Marchalonis, J.J. (1968) Methods used in studies of the structure

of immunoglobulins. In Methods in Immunology and Immunochemistry, C.A. Williams, and M.W. Chase, eds., pp. 405-424, Academic Press, New York.

45. Edelman, G.M. and McClure, W.O. (1968) Fluorescent probes and the conformation of

proteins. Accounts of Chemical Research 1:65-70. 46. Marchalonis, J.J. and Edelman, G.M. (1968) Isolation and characterization of a

hemagglutinin from Limulus polyphemus. J. Mol. Biol. 32:453-465. 47. Fernandez-Moran, H., Marchalonis, J.J., and Edelman, G.M. (1968) Electron

microscopy of a hemagglutinin from Limulus polyphemus. J. Mol. Biol. 32:467-469.

48. Marchalonis, J.J. and Edelman, G.M. (1968) Phylogenetic origins of antibody structure.

III. Antibodies in the primary immune response of the sea lamprey, Petromyzon marinus. J. Exp. Med. 127:891-914.

Gerald M. Edelman Bibliography 49. Edelman, G.M., Gall, W.E., Waxdal, M.J., and Konigsberg, W.H. (1968) The covalent

structure of a human γG-immunoglobulin. I. Isolation and characterization of the whole molecule, the polypeptide chains, and tryptic fragments. Biochemistry 7:1950-1958.

50. Waxdal, M.J., Konigsberg, W.H., Henley, W.L., and Edelman, G.M. (1968) The

covalent structure of human yG-immunoglobulin. II. Isolation and characterization of the cyanogen bromide fragments. Biochemistry 7:1959-1966.

51. Waxdal, M.J., Konigsberg, W.H., and Edelman, G.M. (1968) The covalent structure of

a human yG-immunoglobulin. III. Arrangement of cyanogen bromide fragments. Biochemistry 7:1967-1972.

52. Gall, W.E., Cunningham, B.A., Waxdal, M.J., Konigsberg, W.H., and Edelman, G.M.

(1968) The covalent structure of a human yG-immunoglobulin. IV. The interchain disulfide bonds. Biochemistry 7:1973-1982.

53. Cunningham, B.A., Gottlieb, P.D., Konigsberg, W.H., and Edelman, G.M. (1968) The

covalent structure of a human yG-immunoglobulin. V. Partial amino acid sequence of the light chain. Biochemistry 7:1983-1995.

54. Edelman, G.M. and Gally, J.A. (1968) Antibody structure, diversity, and specificity.

Brookhaven Sym. Biol. 21:328-344. 55. Gottlieb, P.D., Cunningham, B.A., Waxdal, M.J., Konigsberg, W.H., and Edelman, G.M.

(1968) Variable regions of heavy and light polypeptide chains of the same yG-immunoglobulin molecule. Proc. Natl. Acad. Sci. USA 61:168-175.

56. Bennett, G.S. and Edelman, G.M. (1968) Isolation of an acidic protein from rat brain. J.

Biol. Chem. 243:6234-6241. 57. Rutishauser, U., Cunningham, B.A., Bennett, C., Konigsberg, W.H., and Edelman,

G.M. (1968) Amino acid sequence of the Fc region of a human G-immunoglobulin. Proc. Natl. Acad. Sci USA 61:1414-1421.

58. Lindahl, T. and Edelman, G.M. (1968) Polynucleotide ligase from myeloid and

lymphoid tissues. Proc. Natl. Acad. Sci. USA 61:680-687. 59. Bennett, G.S. and Edelman, G.M. (1969) Amino acid incorporation into rat brain

proteins during spreading cortical depression. Science 163:393-395. 60. Lindahl, T., Gally, J.A., and Edelman, G.M. (1969) Deoxyribonuclease IV: A new

exonuclease from mammalian tissues. Proc. Natl. Acad. Sci. USA 62:597-603. 61. Lindahl, T., Gally, J.A., and Edelman, G.M. (1969) Properties of deoxyribonuclease III

from mammalian tissues. J. Biol. Chem. 244:5014-5019.

Gerald M. Edelman Bibliography 62. Edelman, G.M. and Gall, W.E. (1969) The antibody problem. Ann. Rev. Biochem.

38:415-466. 63. Edelman, G.M., Cunningham, B.A., Gall, W.E., Gottlieb, P.D., Rutishauser, U., and

Waxdal, M.J. (1969) The covalent structure of an entire yG-immunoglobulin molecule. Proc. Natl. Acad. Sci. USA 63:78-85.

64. Cunningham, B.A., Pflumm, M.N., Rutishauser, U., and Edelman, G.M. (1969)

Subgroups of amino acid sequences in the variable regions of immunoglobulin heavy chains. Proc. Natl. Acad. Sci. USA 64:997-1003.

65. Pilz, I., Puchwein, G., Kratky, O., Herbst, M., Haager, O., Gall, W.E., and Edelman,

G.M. (1970) Small angle X-ray scattering of a homogeneous yG1 immunoglobulin. Biochemistry 9:211-219.

66. Edelman, G.M. (1970) Prefatory comments on recognition and control at the molecular

level. In The Neurosciences: Second Study Program, F.O. Schmitt, ed., pp. 883-884, Rockefeller University Press, New York.

67. Edelman, G.M. (1970) The structure and genetics of antibodies. In The Neurosciences:

Second Study Program, F.O. Schmitt, ed., pp. 885-900, Rockefeller University Press, New York.

68. Edelman, G.M. and Gally, J.A. (1970) Arrangement and evolution of eukaryotic genes.

In The Neurosciences: Second Study Program, F.O. Schmitt, ed., pp. 962-972, Rockefeller University Press, New York.

69. Gottlieb, P.D., Cunningham, B.A., Rutishauser, U., and Edelman, G.M. (1970) The

covalent structure of a human γG-immunoglobulin. VI. The amino acid sequence of the light chain. Biochemistry 9:3155-3160.

70. Cunningham, B.A., Rutishauser, U., Gall, W.E., Gottlieb, P.D., Waxdal, M.J., and

Edelman, G.M. (1970) The covalent structure of a human yG-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4. Biochemistry 9:3161-3170.

71. Rutishauser, U., Cunningham, B.A., Bennett, C., Konigsberg, W.H., and Edelman,

G.M. (1970) The covalent structure of a human yG-immunoglobulin. VIII. Amino acid sequence of heavy-chain cyanogen bromide fragments H5-H7. Biochemistry 9:3171-3180.

72. Bennett, C., Konigsberg, W.H., and Edelman, G.M. (1970) The covalent structure of a

human yG-immunoglobulin. IX. Assignment of asparaginyl and glutaminyl residues. Biochemistry 9:3181-3187.

Gerald M. Edelman Bibliography 73. Gall, W.E. and Edelman, G.M. (1970) The covalent structure of a human γG-

immunoglobulin. X. Intrachain disulfide bonds. Biochemistry 9:3188-3196. 74. Edelman, G.M. (1970) The covalent structure of a human yG-immunoglobulin. XI.

Functional implications. Biochemistry 9:3197-3204. 75. Edelman, G.M. (1970) Antibody structure: A molecular basis for specificity and control

in the immune response. In Control Processes in Multicellular Organisms, Ciba Foundation Symposium, G.E.W. Wolstenholme and J. Knight, eds., pp. 304-317, Churchill, London.

76. Edelman, G.M. (1970) The complete amino acid sequence and arrangement of

disulfide bonds of a yG-immunoglobulin molecule. In Developmental Aspects of Antibody Formation and Structure, Proceedings of a Symposium held in Prague and Slapy, J. Sterzl and I. Riha, eds., pp. 381-398, Academia Publishing House, Prague.

77. Edelman, G.M. (1970) The structure and function of antibodies. Sci. Am. 223:34-42. 78. Gally, J.A. and Edelman, G.M. (1970) Somatic translocation of antibody genes. Nature

227:341-348. 79. Edelman, G.M. and Gottlieb, P.D. (1970) A genetic marker in the variable region of

light chains of mouse immunoglobulins. Proc. Natl. Acad. Sci. USA 67:1192-1199. 80. Edelman, G.M. (1971) Antibodies: A molecular recognition system. In Theoretical

Physics to Biology, Proceedings of The Second International Conference on Theoretical Physics and Biology, M. Marois, ed., pp. 288-302, S. Karger, Basel.

81. Wang, J.L. and Edelman, G.M. (1971) Fluorescent probes for conformational states of

proteins. IV. The pepsinogen-pepsin conversion. J. Biol. Chem. 246:1185-1191. 82. Wang, J.L., Cunningham, B.A., and Edelman, G.M. (1971) Unusual fragments in the

subunit structure of concanavalin A. Proc. Natl. Acad. Sci. USA 68:1130-1134. 83. Pflumm, M.N., Wang, J.L., and Edelman, G.M. (1971) Conformational changes in

concanavalin A. J. Biol. Chem. 246:4369-4375. 84. Edelman, G.M. and Gall, W.E. (1971) Cascade chromatography and automated

multidimensional fractionation. Proc. Natl. Acad. Sci. USA 68:1444-1449. 85. Cunningham, B.A., Gottlieb, P.D., Pflumm, M.N., and Edelman, G.M. (1971)

Immunoglobulin structure: diversity, gene duplication, and domains. In Progress in Immunology, B. Amos, ed., pp. 3-24, Academic Press, New York.

Gerald M. Edelman Bibliography 86. Quiocho, F.A., Reeke, G.N., Jr., Becker, J.W., Lipscomb, W.N., and Edelman, G.M.

(1971) Structure of concanavalin A at 4Å resolution. Proc. Natl. Acad. Sci. USA 68:1853-1857.

87. Waxdal, M.J., Wang, J.L., Pflumm, M.N., and Edelman, G.M. (1971) Isolation and

order of the cyanogen bromide fragments of concanavalin A. Biochemistry 10:3343-3347.

88. Edelman, G.M., Rutishauser, U., and Millette, C.F. (1971) Cell fractionation and

arrangement on fibers, beads, and surfaces. Proc. Natl. Acad. Sci. USA 68:2153-2157.

89. Edelman, G.M. and Millette, C.F. (1971) Molecular probes of spermatozoan structures.

Proc. Natl. Acad. Sci. USA 68:2436-2440. 90. Becker, J.W., Reeke, G.N., Jr., and Edelman, G.M. (1971) Location of the saccharide

binding site of concanavalin A. J. Biol. Chem. 246:6123-6125. 91. Edelman, G.M. and Gally, J.A. (1971) Molecular immunology. New Sci. 23:213-215. 92. Edelman, G.M. (1971) Antibody structure and molecular immunology. Ann. N.Y. Acad.

Sci. 190:5-25. 93. Yahara, I. and Edelman, G.M. (1972) Restriction of the mobility of lymphocyte

immunoglobulin receptors by concanavalin A. Proc. Natl. Acad. Sci. USA 69:608-612.

94. Edelman, G.M. (1972) Variability, symmetry, and periodicity in the structure of

immunoglobulins. In Cell Interactions, Proceedings of the Third Lepetit Colloquium, L.G. Silvestri, ed., pp. 73-90, North-Holland, Amsterdam.

95. Gally, J.A. and Edelman, G.M. (1972) The genetic control of immunoglobulin synthesis.

Ann. Rev. Genet. 6:1-46. 96. Rutishauser, U., Millette, C.F., and Edelman, G.M. (1972) Specific fractionation of

immune cell populations. Proc. Natl. Acad. Sci. USA 69:1596-1600. 97. Peterson, P.A., Cunningham, B.A., Berggard, I., and Edelman, G.M. (1972) ß2-

microglobulin - A free immunoglobulin domain. Proc. Natl. Acad. Sci. USA 69:1697-1701.

98. Cunningham, B.A., Wang, J.L., Pflumm, M.N., and Edelman, G.M. (1972) Isolation and

proteolytic cleavage of the intact subunit of concanavalin A. Biochemistry 11:3233-3239.

Gerald M. Edelman Bibliography 99. Edelman, G.M., Cunningham, B.A., Reeke, G.N., Jr., Becker, J.W., Waxdal, M.J., and

Wang, J.L. (1972) The covalent and three-dimensional structure of concanavalin A. Proc. Natl. Acad. Sci. USA 69:2580-2584.

100. Rutishauser, U. and Edelman, G.M. (1972) Binding of thymus- and bone marrow-

derived lymphoid cells to antigen-derivatized fibers. Proc. Natl. Acad. Sci. USA 69:3774-3778.

101. Andersson, J., Edelman, G.M., Moller, G., and Sjoberg, O. (1972) Activation of B

lymphocytes by locally concentrated concanavalin A. Eur. J. Immunol. 2:233-235. 102. Gunther, G.R., Wang, J.L., Yahara, I., Cunningham, B.A., and Edelman, G.M. (1973)

Concanavalin A derivatives with altered biological activities. Proc. Natl. Acad. Sci. USA 70:1012-1016.

103. Edelman, G.M., Yahara, I., and Wang, J.L. (1973) Receptor mobility and receptor-

cytoplasmic interactions in lymphocytes. Proc. Natl. Acad. Sci. USA 70:1442-1446.

104. Edelman, G.M. (1973) Antibody structure and molecular immunology. Science

180:830-840. 105. Millette, C.F., Spear, P.G., Gall, W.E., and Edelman, G.M. (1973) Chemical dissection

of mammalian spermatozoa. J. Cell Biol. 58:662-675. 106. Yahara, I. and Edelman, G.M. (1973) The effects of concanavalin A on the mobility of

lymphocyte surface receptors. Exp. Cell Res. 81:143-155. 107. Yahara, I. and Edelman, G.M. (1973) Modulation of lymphocyte receptor redistribution

by concanavalin A, anti-mitotic agents and alterations of pH. Nature 246:152-155. 108. Spear, P.G., Wang, A.-L., Rutishauser, U., and Edelman, G.M. (1973) Charac-

terization of splenic lymphoid cells in fetal and newborn mice. J. Exp. Med. 138:557-573.

109. Edelman, G.M. and Moller, G. (1973) The immune system as a model for cellular

maturation and differentiation. Neurosci. Res. Pro. Bull. 11:91-154. 110. Rutishauser, U., D`Eustachio, P., and Edelman, G.M. (1973) Immunological function

of lymphocytes fractioned with antigen-derivatized fibers. Proc. Natl. Acad. Sci. USA 70:3894-3898.

111. Edelman, G.M. (1973) Structural basis of antibody specificity. In From Theoretical

Physics to Biology, Proceedings of the Third International Conference on Theoretical Physics and Biology, M. Marois, ed., pp. 304-306, S. Karger, Basel.

Gerald M. Edelman Bibliography 112. Edelman, G.M. (1973) Antibody structure and molecular immunology. In Les Prix

Nobel en 1972, (Nobel Lecture, December 12, 1972) pp. 145-170, Nobel Foundation, Stockholm.

113. Edelman, G.M. (1973) Antikorperstruktur und molekulare immunologie (Nobel-

Vortrag) (Antibody structure and molecular immunology). Angew. Chem. 85:1083-1096.

114. Edelman, G.M. (1972) Molecular and cellular mechanisms of clonal selection. In The

Biochemistry of Gene Expression in Higher Organisms, J.W. Lee and J.K. Pollak, eds., pp. 555-573, D. Reidel, Boston.

115. Edelman, G.M. (1973) Nonenzymatic dissociations B. Specific cell fractionation on

chemically derivatized surfaces. In Tissue Culture: Methods and Applications, P. Kruse and M.K. Patterson, eds., pp. 29-36, Academic Press, New York.

116. Edelman, G.M. (1973) Molecular recognition in the immune and nervous systems. In

The Neurosciences: Paths of Discovery, F.G. Worden, J.P. Swazey, and G. Adelman, eds., pp. 65-74, MIT Press, Cambridge.

117. Edelman, G.M. (1974) Surface alterations and mitogenesis in lymphocytes. In Control

of Proliferation in Animal Cells, Cold Spring Harbor Conferences on Cell Proliferation, Vol. 1, B. Clarkson and R. Baserga, eds., pp. 357-379.

118. Edelman, G.M. and Rutishauser, U. (1974) Specific fractionation and manipulation of

cells with chemically derivatized fibers and surfaces. In Methods in Enzymology, Vol. 34, W. Jakoby and M. Wilchek, eds., pp. 195-225, Academic Press, New York.

119. Spear, P.G. and Edelman, G.M. (1974) Maturation of the humoral immune response

in mice. J. Exp. Med. 139:249-263. 120. Edelman, G.M., Spear, P.G., Rutishauser, U., and Yahara, I. (1974) Receptor

specificity and mitogenesis in lymphocyte populations. In The Cell Surface in Development, A.A. Moscona, ed., pp. 141-164, Wiley, New York.

121. Edelman, G.M. (1974) Antibody structure and cellular specificity in the immune

response. The Harvey Lectures 68:149-184. 122. Rutishauser, U., Yahara, I., and Edelman, G.M. (1974) Morphology, motility and

surface behavior of lymphocytes bound to nylon fibers. Proc. Natl. Acad. Sci. USA 71:1149-1153.

123. Gall, W.E., Millette, C.F., and Edelman, G.M. (1974) Chemical and structural analysis

of mammalian spermatozoa. In Physiology and Genetics of Reproduction, Part A, E.M. Coutinho and F. Fuchs, eds., pp. 241-257, Plenum Press, New York.

Gerald M. Edelman Bibliography 124. Edelman, G.M. (1974) Origins and mechanisms of specificity in clonal selection. In

Cellular Selection and Regulation in the Immune Response, G.M. Edelman, ed., pp. 1-38, Raven Press, New York.

125. Edelman, G.M. and Millette, C.F. (1974) Chemical dissection and surface mapping of

mammalian spermatozoa. In The Functional Anatomy of the Spermatozoon, B.A. Afzelius, ed., pp. 349-357, Pergamon Press, Oxford.

126. Edelman, G.M. (1974) Specificity and mechanism at the lymphoid cell surface. In The

Neurosciences: Third Study Program, F.O. Schmitt, and F. Worden, eds., pp. 783-794, MIT Press, Cambridge.

127. Edelman, G.M. (1974) The problem of molecular recognition by a selective system. In

Studies in the Philosophy of Biology, F.J. Ayala and T. Dobzhansky, eds., pp. 45-56, Macmillan Press, London.

128. Gunther, G.R., Wang, J.L., and Edelman, G.M. (1974) The kinetics of cellular

commitment during stimulation of lymphocytes by lectins. J. Cell Biol. 62:366-377. 129. Wang, J.L., Becker, J.W., Reeke, G.N., Jr., and Edelman, G.M. (1974) Favin, a

crystalline lectin from Vicia faba. J. Mol. Biol. 88:259-262. 130. Yang, D.C.H., Gall, W.E., and Edelman, G.M. (1974) Rotational correlation time of

concanavalin A after interaction with a fluorescent probe. J. Bio. Chem. 249:7018-7023.

131. Gall, W.E., Millette, C.F., and Edelman, G.M. (1974) Chemical dissection of

mammalian spermatozoa. In Immunological Approaches to Fertility Control, Karolinska Symposia on Research Methods in Reproductive Endocrinology, E. Diczfalusy, ed., pp. 154-172, Karolinska Institute, Stockholm.

132. Reeke, G.N., Jr., Becker, J.W., Cunningham, B.A., Gunther, G.R., Wang, J.L, and

Edelman, G.M. (1974) Relationships between the structure and activities of concanavalin A. Ann. N.Y. Acad. Sci. 234:369-382.

133. Yahara, I. and Edelman, G.M. (1975) Modulation of lymphocyte receptor mobility by

concanavalin A and colchicine. Ann. Amer. Acad. Sci. 253:455-469. 134. Wang, J.L., Cunningham, B.A., Waxdal, M.J., and Edelman, G.M. (1975) The

covalent and three-dimensional structure of concanavalin A. I. Amino acid sequence of cyanogen bromide fragments F1 and F2. J. Biol. Chem. 250:1490-1502.

Gerald M. Edelman Bibliography 135. Cunningham, B.A., Wang, J.L., Waxdal, M.J., and Edelman, G.M. (1975) The

covalent and three-dimensional structure of concanavalin A. II. Amino acid sequence of cyanogen bromide fragment F3. J. Biol. Chem. 250:1503-1512.

136. Becker, J.W., Reeke, G.N., Jr., Wang, J.L., Cunningham, B.A., and Edelman, G.M.

(1975) The covalent and three-dimensional structure of concanavalin A. III. Structure of the monomer and its interactions with metals and saccharides. J. Biol. Chem. 250:1513-1524.

137. Reeke, G.N., Jr., Becker, J.W., and Edelman, G.M. (1975) The covalent and three-

dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding and quaternary structure. J. Biol. Chem. 250:1525-1547.

138. McClain, D.A., Wang, J.L., and Edelman, G.M. (1975) The effects of sodium

metaperiodate on T and B lymphocytes. Cell. Immunol. 15:287-293. 139. Yahara, I. and Edelman, G.M. (1975) Electron microscopic analysis of the modulation

of lymphocyte receptor mobility. Exp. Cell Res. 91:125-142. 140. Edelman, G.M. (1975) The shock of molecular recognition. In Molecular Approaches

to Immunology, Miami Winter Symposia, Vol. 9, E.E. Smith and D.W. Ribbons, eds., pp. 1-21, Academic Press, New York.

141. Edelman, G.M. (1975) The subject and style of modern immunology: An introduction.

In Molecular Approaches to Immunology Miami Winter Symposia, Vol. 9, E.E. Smith and D.W. Ribbons, eds., pp. 23-38, Academic Press, New York.

142. Sela, B.-A., Wang, J.L., and Edelman, G.M. (1975) Antibodies reactive with cell

surface carbohydrates. Proc. Natl. Acad. Sci. USA 72:1127-1131. 143. Wang, J.L., Gunther, G.R., Yahara, I., Cunningham, B.A., and Edelman, G.M. (1975)

Receptor-cytoplasmic interactions and lymphocyte activation. In Immune Recognition, A.S. Rosenthal, ed., pp. 473-489, Academic Press, New York.

144. Yahara, I. and Edelman, G.M. (1975) Modulation of lymphocyte receptor mobility by

locally bound concanavalin A. Proc. Natl. Acad. Sci. USA 72:1579-1583. 145. Wang, J.L., Gunther, G.R., and Edelman, G.M. (1975) Inhibition by colchicine of the

mitogenic stimulation of lymphocytes prior to the S phase. J. Cell Biol. 66:128-144. 146. Reeke, G.N., Jr., Becker, J.W., Cunningham, B.A., Wang, J.L., Yahara, I., and

Edelman, G.M. (1975) Structure and function of concanavalin A. In Concanavalin A, T.K. Chowdhury and A.K. Weiss, eds., pp. 13-33, Plenum Press, New York.

147. Wang, J.L., McClain, D.A., and Edelman, G.M. (1975) Modulation of lymphocyte

mitogenesis. Proc. Natl. Acad. Sci. USA 72:1917-1921.

Gerald M. Edelman Bibliography 148. Edelman, G.M. (1975) Receptor interactions and mitogenesis in lymphoid cells. In

Functional Linkage in Biomolecular Systems, F.O. Schmitt, D.M. Schneider and D.M. Crother, eds., pp. 188-201, Raven Press, New York.

149. Sela, B.-A., Wang, J.L., and Edelman, G.M. (1975) Isolation of lectins of different

specificities on a single affinity adsorbent. J. Biol. Chem. 250:7535-7538. 150. D`Eustachio, P. and Edelman, G.M. (1975) Frequency and avidity of specific antigen-

binding cells in developing mice. J. Exp. Med. 142:1078-1091. 151. Schrader, J.W., Cunningham, B.A., and Edelman, G.M. (1975) Functional interactions

of viral and histocompatibility antigens at tumor cell surfaces. Proc. Natl. Acad. Sci. USA 72:5066-5070.

152. Rutishauser, U., Yang, D.C.H., Thiery, J.-P., and Edelman, G.M. (1975) Expression

and behavior of cell surface receptors in development. In Developmental Biology, ICN-UCLA Symposia on Molecular and Cellular Biology, Vol. 2, D. McMahon and C.F. Fox, eds., pp. 3-18, W.A. Benjamin, Menlo Park, California.

153. Henning, R., Milner, R.J., Reske, K., Cunningham, B.A., and Edelman, G.M. (1976)

Subunit structure, cell surface orientation, and partial amino- acid sequences of murine histocompatibility antigens. Proc. Natl. Acad. Sci. USA 73:118-122.

154. Becker, J.W., Reeke, G.N., Jr., Cunningham, B.A., and Edelman, G.M. (1976) New

evidence on the location of the saccharide binding site of con-canavalin A. Nature 259:406-409.

155. Rutishauser, U., Thiery, J.-P., Brackenbury, R., Sela, B.-A., and Edelman, G.M.

(1976) Mechanism of adhesion among cells from neural tissues of the chick embryo. Proc. Natl. Acad. Sci. USA 73:577-581.

156. Schrader, J.W. and Edelman, G.M. (1976) Participation of the H-2 antigens of tumor

cells in their lysis of syngeneic T cells. J. Exp. Med. 143:601-614. 157. Sela, B.-A., Wang, J.L., and Edelman, G.M. (1976) Lymphocyte activation by

monovalent fragments of antibodies reactive with cell surface carbohydrates. J. Exp. Med. 143:665-671.

158. Gunther, G.R., Wang, J.L. and Edelman, G.M. (1976) Kinetics of colchicine inhibition

of mitogenesis in individual lymphocytes. Exp. Cell Res. 98:15-22. 159. Fraser, A.R., Hemperly, J.J., Wang, J.L., and Edelman, G.M. (1976) Monovalent

derivatives of concanavalin A. Proc. Natl. Acad. Sci. USA 73:790-794.

Gerald M. Edelman Bibliography 160. Edelman, G.M. (1976) Surface modulations in cell recognition and cell growth.

Science 192:218-226. 161. Cunningham, B.A., Henning, R., Schrader, J.W., Milner, R.J., Reske, K., and

Edelman, G.M. (1976) Structure and biological activity of H-2 antigens. In The Role of the Products of the Histocompatibility Gene Complex in Immune Responses, D.H. Katz and B. Benacerraf, eds., pp. 667-676, Academic Press, New York.

162. Cunningham, B.A., Sela, B.-A., Yahara, I., and Edelman, G.M. (1976) Structure and

activities of lymphocyte mitogens. In The Role of Mitogens in Immunobiology, J.J. Oppenheim and D.L. Rosenstreich, eds., pp. 13-30, Academic Press, New York.

163. Wang, J.L., Gunther, G.R., McClain, D.A., and Edelman, G.M. (1976) Biochemical

signals modulating lymphocyte mitogenesis. In The Role of Mitogens in Immunobiology, J.J. Oppenheim and D.L. Rosenstreich, eds., pp. 103-117, Academic Press, New York.

164. Edelman, G.M. and Wang, J.L. (1976) The cell surface membrane-complex in cell

interactions. In Cell Surfaces and Malignancy: A Workshop, P.T. Mora ed., pp. 83-104, National Institutes of Health, Bethesda, Maryland.

165. Edelman, G.M. (1976) Erkennung und Kontrolle an der Zelloberflache (Recog- nition

and control at the cell surface). Naturwissenschaftliche Rundschau 5:145-150. 166. Edelman, G.M. and Yahara, I. (1976) Temperature-sensitive changes in surface

modulating assemblies of fibroblasts transformed by mutants of Rous sarcoma virus. Proc. Natl. Acad. Sci. USA 73:2047-2051.

167. Wang, J.L., Sela, B.-A., McClain, D.A., and Edelman, G.M. (1976) Modulation of

lymphocyte mitogenesis. In Leukocyte Membrane Determinants Regulating Immune Reactivity, V.P. Eijsvoogel, ed., pp. 19-31, Academic Press, New York.

168. Edelman, G.M. (1976) Molecular mechanisms of cell proliferation and cell recognition.

J. Biochem. 79:23-27. 169. Jazwinski, S.M., Wang, J.L., and Edelman, G.M. (1976) Initiation of replication in

chromosomal DNA induced by extracts from proliferating cells. Proc. Natl. Acad. Sci. USA 73:2231-2235.

170. Fraser, A.R., Wang, J.L., and Edelman, G.M. (1976) Formation of hybrid

concanavalin A molecules by subunit exchange. J. Biol. Chem. 251:4622-4628. 171. D`Eustachio, P., Cohen, J.E., and Edelman, G.M. (1976) Variation and control of

specific antigen-binding cell populations in individual fetal mice. J. Exp. Med. 144:259-265.

Gerald M. Edelman Bibliography 172. Henning, R., Schrader, J.W., and Edelman, G.M. (1976) Anti-viral antibodies inhibit

the lysis of tumor cells by anti-H-2 sera. Nature 263:689-691. 173. Jazwinski, S.M. and Edelman, G.M. (1976) Activity of yeast extracts in cell-free

stimulation of DNA replication. Proc. Natl. Acad. Sci. USA 73:3933-3936. 174. McClain, D.A. and Edelman, G.M. (1976) Analysis of the stimulation-inhibition

paradox exhibited by lymphocytes exposed to concanavalin A. J. Exp. Med. 144:1494-1508.

175. Milner, R.J., Henning, R., and Edelman, G.M. (1976) Identification of the murine

leukemia viral antigens detected on mouse cells by H-2 alloantisera. Eur. J. Immunol. 6:603-607.

176. Edelman, G.M., Wang, J.L., and Yahara, I. (1976) Surface-modulating assemblies in

mammalian cells. In Cell Motility, Vol. 3, R.D. Goldman, T.D. Pollard, and J.L. Rosenbaum, eds., pp. 305-321, Cold Spring Harbor Press, Cold Spring Harbour, New York.

177. Becker, J.W., Cunningham, B.A., Reeke, G.N., Jr., Wang, J.L., and Edelman, G.M.

(1976) The molecular structure of concanavalin A. In Concanavalin A as a Tool, H. Bittiger and H.P. Schnebli, eds., pp. 33-54, Wiley, London.

178. Rutishauser, U. and Edelman, G.M. (1976) Fractionation and manipulation of cells

with concanavalin A-coated fibers. In Concanavalin A as a Tool, H. Bittiger and H.P. Schnebli, eds., pp. 447-465, Wiley, London.

179. Wang, J.L., Gunther, G.R., and Edelman, G.M. (1976) Chemical and biologi-cal

properties of concanvalin A derivatives. In Concanavalin A as a Tool, H. Bittiger and H.P. Schnebli, eds., pp. 585-598, Wiley, London.

180. Henning, R., Schrader, J.W., Milner, R.J., Reske, K., Ziffer, J.A., Cunningham, B.A.,

and Edelman, G.M. (1976) Chemical structure and biological activities of murine histocompatibility antigens. In 27th Mosbacher Colloquium, Annual Meeting of the Germany Society of Biological Chemistry, F. Melchers and K. Rajewsky, eds., pp. 235-247, Springer-Verlag, Berlin.

181. Sela, B.-A. and Edelman, G.M. (1977) Isolation by cell-column chromatography of

immunoglobulins specific for cell surface carbohydrates. J. Exp. Med. 145:443-449.

182. McClain, D.A., D`Eustachio, P., and Edelman, G.M. (1977) Role of surface

modulating assemblies in growth control of normal and transformed fibroblasts. Proc. Natl. Acad. Sci. USA 74:666-670.

Gerald M. Edelman Bibliography 183. Schrader, J.W. and Edelman, G.M. (1977) Joint recognition by cytotoxic T cells of

inactivated Sendai virus and products of the major histocompatibility complex. J. Exp. Med. 145:523-539.

184. Schlessinger, J., Elson, E.L., Webb, W.W., Yahara, I., Rutishauser, U., and Edelman,

G.M. (1977) Receptor diffusion on cell surfaces modulated by locally-bound concanavalin A. Proc. Natl. Acad. Sci. USA 74:1110-1114.

185. Cunningham, B.A., Henning, R., Milner, R.J., Reske, K., Siffer, J.A., and Edelman,

G.M. (1977) Structure of murine histocompatibility antigens. In Cold Spring Harbor Symposium on Quant. Bio. 41: 351-362.

186. Schrader, J.W., Henning, R., Milner, R.J., and Edelman, G.M. (1977) The recognition

of H-2 and viral antigens by cytotoxic T cells. In Cold Spring Harbor Symposium on Quant. Bio. 41:547-557.

187. Edelman, G.M. (1977) Understanding selective molecular recognition. In Cold Spring

Harbor Symposium on Quant. Bio. 41:891-902. 188. Edelman, G.M. (1977) Transmembrane control and surface modulation in animal

cells. In Cell Shape and Surface Architecture, pp. 467-480, Alan R. Liss, New York.

189. Thiery, J.-P., Brackenbury, R., Rutishauser, U., and Edelman, G.M. (1977) Adhesion

among neural cells of the chick embryo. In Cellular Neurobioogy, pp. 199-206, Alan R. Liss, New York.

190. Rutishauser, U. and Edelman, G.M. (1977) Fractionation and manipulation of cells

with chemically modified fibers and surfaces. In Methods of Cell Separation, N. Catsimpoolas, ed., pp. 193-228, Plenum Press, New York.

191. Becker, J.W., Reeke, G.N., Jr., and Edelman, G.M. (1978) Structural studies on

lectins and lectin-saccharide interactions. In Cell Surface Carbohydrate Chemistry, R.E. Harmon, ed., pp. 135-151, Academic Press, New York.

192. D`Eustachio, P., Rutishauser, U., and Edelman, G.M. (1977) Clonal selection and the

ontogeny of the immune response. In International Review of Cytology, G.H. Bourne and J.F. Danielli, eds., pp. 1-55, Academic Press, New York.

193. Edelman, G.M. (1977) Cell surface modulation. In Cancer Biology. IV. Differentiation

and Carcinogenesis, C. Borek, C.M. Fenoglio, and D.W. King, eds., pp. 18-29, Stratton Intercontinental, New York.

194. Cohen, J.E., D`Eustachio, P., and Edelman, G.M. (1977) The specific antigen-binding

cell populations of individual fetal mouse spleens: repertoire composition, size, and genetic control. J. Exp. Med. 146:394-411.

Gerald M. Edelman Bibliography 195. McClain, D.A. and Edelman, G.M. (1978) Surface modulation and trans-membrane

control. In The Molecular Basis of Cell-Cell Interaction, R.A. Lerner and D. Bergsma, eds., pp. 1-28, Alan R. Liss, New York.

196. Edelman, G.M., D`Eustachio, P., McClain, D.A., and Jazwinski, S.M. (1977) Surface

signals and cellular regulation of growth. In Mitosis: Facts and Questions, M. Little, N. Paweletz, C. Petzelt, H. Ponstingl, D. Schroeter, and H.-P. Zimmerman, eds., pp. 20-42, Springer-Verlag, Berlin.

197. Jazwinski, S.M., McClain, D.A., D`Eustachio, P., and Edelman, G.M. (1978) Surface

signals and cellular regulation of growth. In Carcinogenesis, a Comprehensive Survey: Mechanisms of Tumor Promotion and Cocarcinogenesis, Vol. 2, T.J. Slaga, A. Sivak, and R.K. Boutwell, eds., pp. 343-361, Raven Press, New York.

198. Cunningham, B.A., Milner, R.J., Schrader, J.W., Reske, K., Henning, R., Ziffer, J.A.,

and Edelman, G.M. (1978) The structure of H-2 antigens and their role in tumor cell recognition. In Cell Differentiation and Neoplasia, G.F. Saunders, ed., pp. 163-176, Raven Press, New York.

199. Brackenbury, R., Thiery, J.-P., Rutishauser, U., and Edelman, G.M. (1977) Adhesion

among neural cells of the chick embryo. I. An immunological assay for molecules involved in cell-cell binding. J. Biol. Chem. 252:6835-6840.

200. Thiery, J.-P., Brackenbury, R., Rutishauser, U., and Edelman, G.M. (1977) Adhesion

among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina. J. Biol. Chem. 252:6841-6845.

201. Rutishauser, U. Brackenbury, R., Thiery, J.-P., and Edelman, G.M. (1978) Cell

adhesion molecules from neural tissues of the chick embryo. In The Molecular Basis of Cell-Cell Interaction, R.A. Lerner and D. Bergsma, eds., pp. 305-316, Alan R. Liss, New York.

202. Webb, C.G., Gall, W.E., and Edelman, G.M. (1977) Synthesis and distribution of H-2

antigens in preimplantation mouse embryos. J. Exp. Med. 146:923-932. 203. Becker, J.W., Ziffer, J.A., Edelman, G.M., and Cunningham, B.A. (1977)

Crystallographic studies of bovine ß2-microglobulin. Proc. Natl. Acad. Sci. USA 74:3345-3349.

204. Edelman, G.M. (1979) Group selection and phasic reentrant signaling: a theory of

higher brain function. In The Neurosciences: Fourth Study Program, F.O. Schmitt and F. Worden, eds., pp. 1115-1140, MIT Press, Cambridge.

Gerald M. Edelman Bibliography 205. McClain, D.A., D`Eustachio, P., and Edelman, G.M. (1977) Surface modulating

assemblies and the control of cell growth. In Early Proteins of Oncogenic DNA Viruses, pp. 379-393, INSERM, Paris.

206. McClain, D.A. and Edelman, G.M. (1979) Dynamics of the cell surface: Modulation

and transmembrane control. In The Neurosciences: Fourth Study Program, F.O. Schmitt and F. Worden, eds., pp. 675-689, MIT Press, Cambridge.

207. Rutishauser, U., Thiery, J.-P., Brackenbury, R., and Edelman, G.M. (1979) Surface

molecules mediating interactions among embryonic neural cells, In The Neurosciences: Fourth Study Program, F.O. Schmitt and F. Worden, eds., pp. 735-747, MIT Press, Cambridge.

208. Wang, J.L. and Edelman, G.M. (1978) Binding and functional properties of

concanavalin A and its derivatives. I. Monovalent, divalent and tetravalent derivatives stable at physiological pH. J. Biol. Chem. 253:3000-3007.

209. Wang, J.L. and Edelman, G.M. (1978) Binding and functional properties of

concanavalin A and its derivatives. II. A proteolytic product with saccharide-binding activity. J. Biol. Chem. 253:3008-3015.

210. Edelman, G.M. and Wang, J.L. (1978) Binding and functional properties of

concanavalin A and its derivatives. III. Interactions with indoleacetic acid and other hydrophobic ligands. J. Biol. Chem. 253:3016-3022.

211. Rutishauser, U., Brackenbury, R., Thiery, J.-P., and Edelman, G.M. (1979) Surface

molecules involved in interactions among neural cells during development. In Recent Advances in the Developmental Biology of Central Nervous System Malformations, N.C. Myrianthopoulos and D. Bergsma, eds., pp. 79-92, Alan R. Liss, New York.

212. Maness, P.F. and Edelman, G.M. (1978) Inactivation and chemical alteration of

mating factor by cells and spheroplasts of yeast. Proc. Natl. Acad. Sci. USA 75:1304-1308.

213. Edelman, G.M. (1978) Group selection and phasic reentrant signaling: A theory of

higher brain function. In The Mindful Brain: Cortical Organization and the Group-Selective Theory of Higher Brain Function, by G.M. Edelman and V.B. Mountcastle, pp. 51-100, MIT Press, Cambridge.

214. Reeke, G.N., Jr., Becker, J.W., and Edelman, G.M. (1978) Changes in the three-

dimensional structure of concanavalin A upon demetallization. Proc. Natl. Acad. Sci. USA 75:2286-2290.

Gerald M. Edelman Bibliography 215. Rutishauser, U. and Edelman, G.M. (1978) Transmembrane control and cell surface

recognition. In Differentiation and Development, Miami Winter Symposia, Vol. 15, F. Ahmad et al., eds., pp. 221-233, Academic Press, New York.

216. McClain, D.A., Maness, P.F., and Edelman, G.M. (1978) Assay for early cytoplasmic

effects of the src gene product of Rous sarcoma virus. Proc. Natl. Acad. Sci. USA 75:2750-2754.

217. Rutishauser, U., Thiery, J.-P., Brackenbury, R., and Edelman, G.M. (1978) Adhesion

among neural cells of the chick embryo. III. Relationship of the surface molecule CAM to cell adhesion and the development of histotypic patterns. J. Cell Biol. 79:371-381.

218. Rutishauser, U., Gall, W.E., and Edelman, G.M. (1978) Adhesion among neural cells

of the chick embryo. IV. Role of the cell surface molecule (CAM) in the formation of neurite bundles in cultures of spinal ganglia. J. Cell Biol. 79:382-393.

219. D`Eustachio, P., Cohen, J.C., and Edelman, G.M. (1979) The ontogeny of antigen-

binding cells. In Developmental Immunobiology, G.W. Siskind et al., eds., pp. 133-158, Grune & Stratton, New York.

220. Gall, W.E. and Edelman, G.M. (1979) Cell surface modulation and trans-membrane

control. In Advances in Inflammation Research, Vol. 1, G. Weissmann et al., eds., pp. 43-53, Raven Press, New York.

221. Jazwinski, S.M., and Edelman, G.M. (1979) Replication in vitro of the 2-µm DNA

plasmid of yeast. Proc. Natl. Acad. Sci. USA 76:1223-1227. 222. Cunningham, B.A., Hemperly, J.J., Hopp, T.P., and Edelman, G.M. (1979) Favin

versus concanavalin A: A circularly permuted amino acid sequence. Proc. Natl. Acad. Sci. USA 76:3218-3222.

223. Lingappa, V.R., Cunningham, B.A., Jazwinski, S.M., Hopp, T.P., Blobel, G., and

Edelman, G.M. (1979) Cell-free synthesis and segregation of ß2-microglobulin. Proc. Natl. Acad. Sci. USA 76:3651-3655.

224. Maness, P.F., Engeser, H., Greenberg, M.E., O`Farrell, M., Gall, W.E., and Edelman,

G.M. (1979) Characterization of the protein kinase activity of the src gene product of the avian sarcoma virus. Proc. Natl. Acad. Sci. USA 76:5028-5032.

225. Jorgenson, O.S., Delouvée, A., Thiery, J.-P., and Edelman, G.M. (1980) The nervous

system specific protein D2 is involved in adhesion among neurites from cultured rat ganglia. FEBS Letters 111, No. 1, 39-42.

Gerald M. Edelman Bibliography 226. Maness, P.F., Engeser, H., Greenberg, M.E., O`Farrell, M., Gall, W.E., and Edelman,

G.M. (1980) Activities of the src gene product of the avian sarcoma virus. In Cold Spring Harbor Symposium on Quant. Bio. 44: 949-958.

227. Edelman, G.M. (1981) Group selection as the basis for higher brain function. In The

Organization of the Cerebral Cortex, F.O. Schmitt et al., eds., pp. 535-563, MIT Press, Cambridge.

228. McClain, D.A. and Edelman, G.M. (1980) Density-dependent stimulation and

inhibition of cell growth by agents that disrupt microtubules. Proc. Natl. Acad. Sci. USA 77:2748-2752.

229. Taketo, M., Jazwinski, S.M., and Edelman, G.M. (1980) Association of the 2-µm

plasmid with yeast folded chromosomes. Proc. Natl. Acad. Sci. USA 77:3144-3148.

230. Rothbard, J.B., Hopp, T.P., Edelman, G.M., and Cunningham, B.A. (1980) Structure

of the heavy chain of the H-2Kk histocompatibility antigen. Proc. Natl. Acad. Sci. USA 77:4239-4243.

231. Buskirk, D.R., Thiery, J.-P., Rutishauser, U., and Edelman, G.M. (1980) Antibodies to

a neural cell adhesion molecule disrupt histogenesis in cultured chick retinae. Nature 285:488-489.

232. Bertolotti, R., Rutishauser, U., and Edelman, G.M. (1980) A cell surface molecule

involved in aggregation of embryonic liver cells. Proc. Natl. Acad. Sci. USA 77:4831-4835.

233. Rutishauser, U. and Edelman, G.M. (1980) Effects of fasciculation on the outgrowth

of neurites from spinal ganglia in culture. J. Cell Biol. 87:370-378. 234. Brackenbury, R., Rutishauser, U., and Edelman, G.M. (1981) Distinct calcium-

independent and calcium-dependent adhesion systems of chick embryo cells. Proc. Natl. Acad. Sci. USA 78:387-391.

235. Gall, W.E. and Edelman, G.M. (1981) Lateral diffusion of surface molecules in animal

cells and tissues. Science 213:903-905. 236. Edelman, G.M. and Rutishauser, U. (1981) Molecules involved in cell-cell adhesion

during development. J. Supramol. Struct. Cell. Biochem. 16:259-262. 237. Rutishauser, U., Hoffman, S., and Edelman, G.M. (1982) Binding properties of a cell

adhesion molecule from neural tissue. Proc. Natl. Acad. Sci. USA 79:685-689.

Gerald M. Edelman Bibliography 238. Grumet, M., Rutishauser, U., and Edelman, G.M. (1982) Neural cell adhesion

molecule is on embryonic muscle cells and mediates adhesion to nerve cells in vitro. Nature 295:693-695.

239. Hoffman, S., Sorkin, B.C., White, P.C., Brackenbury, R., Mailhammer, R.,

Rutishauser, U., Cunningham, B.A., and Edelman, G.M. (1982) Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes. J. Biol. Chem. 257:7720-7729.

240. Edelman, G.M. and Reeke, G.N., Jr. (1982) Selective networks capable of

representative transformation, limited generalizations, and associative memory. Proc. Natl. Acad. Sci. USA 79:2091-2095.

241. Jazwinski, S.M. and Edelman, G.M. (1982) Protein complexes from active replicative

fractions associate in vitro with the replication origins of yeast 2-µm DNA plasmid. Proc. Natl. Acad. Sci. USA 79:3428-3432.

242. Rothbard, J.B., Brackenbury, R., Cunningham, B.A., and Edelman, G.M. (1982)

Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains. J. Biol. Chem. 257:11064-11069.

243. Chuong, C.-M., McClain, D.A., Streit, P., and Edelman, G.M. (1982) Neural cell

adhesion molecules in rodent brains isolated by monoclonal antibodies with cross-species reactivity. Proc. Natl. Acad. Sci. USA 79:4234-4238.

244. McClain, D.A. and Edelman, G.M. (1982) A neural cell adhesion molecule from

human brain. Proc. Natl. Acad. Sci. USA 79:6380-6384. 245. Thiery, J.-P., Duband, J.-L., Rutishauser, U., and Edelman, G.M. (1982) Cell

adhesion molecules in early chick embryogenesis. Proc. Natl. Acad. Sci. USA 79:6737-6741.

246. Edelman, G.M. and Chuong, C.-M. (1982) Embryonic to adult conversion of neural

cell adhesion molecules in normal and staggerer mice. Proc. Natl. Acad. Sci. USA 79:7036-7040.

247. Edelman, G.M. (1982) Through a computer darkly: Group selection and higher brain

function. Bull. Am. Acad. Arts Sci. 36:18-49. 248. Gallin, W.J., Edelman, G.M., and Cunningham, B.A. (1983) Characterization of L-

CAM, a major cell adhesion molecule from embryonic liver cells. Proc. Natl. Acad. Sci. USA 80:1038-1042.

249. Edelman, G.M. (1983) Cell adhesion molecules. Science 219:450-457.

Gerald M. Edelman Bibliography 250. Jazwinski, S.M., Niedzwiecka, A., and Edelman, G.M. (1983) In vitro association of a

replication complex with a yeast chromosomal replicator. J. Biol. Chem. 258:2754-2757.

251. Greenberg, M.E. and Edelman, G.M. (1983) Comparison of the 34,000-da pp60s

rc substrate and a 38,000-da phosphoprotein identified by monoclonal antibodies. J. Biol. Chem. 258:8497-8502.

252. Cunningham, B.A., Hoffman, S., Rutishauser, U., Hemperly, J.J., and Edelman, G.M.

(1983) Molecular topography of N-CAM: surface orientation and location of sialic acid-rich and binding regions. Proc. Natl. Acad. Sci. USA 80:3116-3120.

253. Rutishauser, U., Grumet, M., and Edelman, G.M. (1983) N-CAM mediates initial

interactions between spinal cord neurons and muscle cells in culture. J. Cell Biol. 97:145-152.

254. Greenberg, M.E. and Edelman, G.M. (1983) The 34kD-pp60src substrate is located at

the inner face of the plasma membrane. Cell 33:767-779. 255. Edelman, G.M. and Finkel, L.H. (1984) Neuronal group selection in the cerebral

cortex. In Dynamic Aspects of Neo-Cortical Function, G.M. Edelman, W.E. Gall, and W.M. Cowan, eds., pp. 653-695, Wiley, New York.

256. Edelman, G.M., Gallin, W.J., Delouvée, A., Cunningham, B.A., and Thiery, J.-P.

(1983) Early epochal maps of two different cell adhesion molecules. Proc. Natl. Acad. Sci. USA 80:4384-4388.

257. Reeke, G.N., Jr. and Edelman, G.M. (1984) Selective networks and recognition

automata. Ann. N.Y. Acad. Sci. 426:181-201. 258. Hoffman, S. and Edelman, G.M. (1983) Kinetics of homophilic binding by E and A

forms of the neural cell adhesion molecule. Proc. Natl. Acad. Sci. USA 80:5762-5766.

259. Edelman, G.M., Hoffman, S., Chuong, C.-M., Thiery, J.-P., Brackenbury, R., Gallin,

W.J., Grumet, M., Greenberg, M.E., Hemperly, J.J., Cohen, C., and Cunningham, B.A. (1983) Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. In Cold Spring Harbor Symposium Quant. Bio. 48:515-526.

260. Grumet, M., Rutishauser, U., and Edelman, G.M. (1983) Neuron-glia adhesion is

inhibited by antibodies to neural determinants. Science 222:60-62. 261. Edelman, G.M. (1984) Modulation of cell adhesion during induction, histogenesis, and

perinatal development of the nervous system. Ann. Rev. Neurosci. 7:339-377.

Gerald M. Edelman Bibliography 262. Greenberg, M.E., Brackenbury, R., and Edelman, G.M. (1983) Subcellular localization

and tissue distribution of the 34kD tyrosine kinase substrate. In Cold Spring Harbor Conferences on Cell Proliferation and Cancer, Vol. II, G.F. Vande Woude, A.J. Levine, W.C. Topp, and J.D. Watson, eds., pp. 99-108, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.

263. Grumet, M., Hoffman, S., and Edelman, G.M. (1984) Two antigenically related

neuronal CAMs of different specificities mediate neuron-neuron and neuron-glia adhesion. Proc. Natl. Acad. Sci. USA 81:267-271.

264. Thiery, J.-P., Delouvée, A., Gallin, W.J., Cunningham, B.A., and Edelman, G.M.

(1984) Ontogenetic expression of cell adhesion molecules: L-CAM is found in epithelia derived from the three primary germ layers. Dev. Biol. 102:61-78.

265. Greenberg, M.E., Brackenbury, R., and Edelman, G.M. (1984) Changes in the

distribution of the 34-Kdalton tyrosine kinase substrate during differentiation and maturation of chicken tissues. J. Cell Biol. 98:473-486.

266. Greenberg, M.E., Brackenbury, R., and Edelman, G.M. (1984) Alteration of neural cell

adhesion molecule (N-CAM) expression after neuronal cell transformation by Rous sarcoma virus. Proc. Natl. Acad. Sci. USA 81:969-973.

267. Edelman, G.M. (1984) Cell adhesion and morphogenesis: The regulator hypothesis.

Proc. Natl. Acad. Sci. USA 81:1460-1464. 268. Edelman, G.M. (1984) Cell surface modulation and marker multiplicity in neural

patterning. Trends Neurosci. 7:78-84. 269. Hoffman, S. and Edelman, G.M. (1984) The mechanism of binding of neural cell

adhesion molecules. In Gene Expression and Cell-Cell Interactions in the Developing Nervous System, J.M. Lauder and P. Nelson, eds., pp. 147-160, Plenum Press, New York.

270. Jazwinski, M.S. and Edelman, G.M. (1984) Evidence for participation of a multiprotein

complex in yeast DNA replication in vitro. J. Biol. Chem. 259:6852-6857. 271. Edelman, G.M. (1984) Cell adhesion molecules: a molecular basis for animal form.

Sci. Am. 250:118-129. 272. Chuong, C.-M. and Edelman, G.M. (1984) Alterations in neural cell adhesion

molecules during development of different regions of the nervous system. J. Neurosci. 4:2354-2368.

273. Grumet, M. and Edelman, G.M. (1984) Heterotypic binding between neuronal

membrane vesicles and glial cells is mediated by a specific neuron-glial cell adhesion molecule. J. Cell Biol. 98:1746-1756.

Gerald M. Edelman Bibliography 274. Fraser, S.E., Murray, B.A., Chuong, C.-M., and Edelman, G.M. (1984) Alteration of

the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:4222-4226.

275. Murray, B.A., Hemperly, J.J., Gallin, W.J., MacGregor, J.S., Edelman, G.M., and

Cunningham, B.A. (1984) Isolation of cDNA clones for the chicken neural cell adhesion molecule (N-CAM). Proc. Natl. Acad. Sci. USA 81:5584-5588.

276. Sorkin, B.C., Hoffman, S., Edelman, G.M., and Cunningham, B.A. (1984) Sulfation

and phosphorylation of the neural cell adhesion molecule N-CAM. Science 225:1476-1478.

277. Cunningham, B.A., Leutzinger, Y., Gallin, W.J., Sorkin, B.C., and Edelman, G.M.

(1984) Linear organization of the liver cell adhesion molecule L-CAM. Proc. Natl. Acad. Sci. USA 81:5787-5791.

278. Hoffman, S., Chuong, C.-M., and Edelman, G.M. (1984) Evolutionary conser- vation

of key structures and binding functions of neural cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:6881-6885.

279. Brackenbury, R., Greenberg, M.E., and Edelman, G.M. (1984) Phenotypic changes

and loss of N-CAM mediated adhesion in transformed embryonic chicken retinal cells. J. Cell Biol. 99:1944-1954.

280. Crossin, K.L., Edelman, G.M., and Cunningham, B.A. (1984) Mapping of three

carbohydrate attachment sites in embryonic and adult forms of the neural cell adhesion molecules (N-CAM). J. Cell Biol. 99:1848-1855.

281. Grumet, M., Hoffman, S., Chuong, C.-M., and Edelman, G.M. (1984) Polypep-tide

components and binding functions of neuron-glia cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:7989-7993.

282. Edelman, G.M. (1985) Cell adhesion and the molecular processes of morpho-

genesis. Ann. Rev. Biochem. 54:135-169. 283. Jazwinski, S.M. and Edelman, G.M. (1984) A replisome may be involved in yeast

DNA replication. Ann. N.Y. Acad. Sci. 435:161-163. 284. Edelman, G.M. (1985) Molecular regulation of neural morphogenesis. In Molecular

Bases of Neural Development, G.M. Edelman, W.E. Gall, W.M. Cowan, eds., pp. 35-59, Wiley, New York.

285. Antler, A.M., Greenberg, M.E., Edelman, G.M., and Hanafusa, H. (1985) Increased

phosporylation of tyrosine in vinculin does not occur upon transformation by some avian Sarcoma viruses. Mol. Cell. Biol. 1:263-267.

Gerald M. Edelman Bibliography 286. Thiery, J.-P., Delouvée, A., Grumet, M., and Edelman, G.M. (1985) Initial appearance

and regional distribution of the neuron-glia cell adhesion molecule (Ng-CAM) in the chick embryo. J. Cell Biol. 100:442-456.

287. Finkel, L.H. and Edelman, G.M. (1985) Interaction of synaptic modification rules

within populations of neurons. Proc. Natl. Acad. Sci. USA 82:1291-1295. 288. Jazwinski, S.M. and Edelman, G.M. (1985) A DNA primase for yeast: Purification and

partial characterization. J. Biol. Chem. 260:4995-5002. 289. Edelman, G.M. (1985) Modulation mechanisms in cell-cell recognition. Trends

Pharmacol. Sci. 6:208-214. 290. Gallin, W.J., Prediger, E.A., Edelman, G.M., and Cunningham, B.A. (1985) Isolation

of a cDNA clone for the liver cell adhesion molecule (L-CAM). Proc. Natl. Acad. Sci. USA 82:2809-2813.

291. Rieger, F., Grumet, M., and Edelman, G.M. (1985) N-CAM at the vertebrate

neuromuscular junction. J. Cell Biol. 101:285-293. 292. Friedlander, D.R., Brackenbury, R., and Edelman, G.M. (1985) Conversion of

embryonic form to adult forms of N-CAM in vitro results from de novo synthesis of adult forms. J. Cell Biol. 101:412-419.

293. Chuong, C.-M. and Edelman, G.M. (1985) Expression of cell adhesion molecules in

embryonic induction. I. Morphogenesis of nestling feathers. J. Cell Biol. 101:1009-1026.

294. Chuong, C.-M. and Edelman, G.M. (1985) Expression of cell adhesion molecules in

embryonic induction. II. Morphogenesis of adult feathers. J. Cell Biol. 101:1027-1043.

295. Crossin, K.L., Chuong, C.-M., and Edelman, G.M. (1985) Expression sequences of

cell adhesion molecules. Proc. Natl. Acad. Sci. USA 82:6942-6946. 296. D'Eustachio, P., Owens, G., Edelman, G.M., and Cunningham, B.A. (1985)

Chromosomal location of the gene encoding to the neural cell adhesion molecule (N-CAM) in the mouse. Proc. Natl. Acad. Sci. USA 82:7631-7635.

297. Grumet, M., Hoffman, S., Crossin, K.L., and Edelman, G.M. (1985) Cytotactin, an

extracellular matrix protein of neural and non-neural tissues that mediates glia-neuron interaction. Proc. Natl. Acad. Sci. USA 82:8075-8079.

Gerald M. Edelman Bibliography 298. Hoffman, S., Grumet, M., and Edelman, G.M. (1985) Cell adhesion molecules in the

histogenesis of nerve and muscle. In Cardiac Morphogenesis, V. Ferrans, G. Rosenquist, and C. Weinstein, eds., pp. 36-43, Elsevier Press, New York.

299. Edelman, G.M. (1985) Expression of cell adhesion molecules during embryogenesis

and regeneration. Exp. Cell Res. 161:1-16. 300. Edelman, G.M. (1985) CAM expression and the regulation of morphogenesis. In Cold

Spring Harbor Symposium on Quantitatiave Biology. 50:877-889. 301. Edelman, G.M., Hoffman, S., Chuong, C.-M., and Cunningham, B.A. (1985) The

molecular bases and dynamics of cell adhesion in embryogenesis. UCLA Symposium Mol. Cell. Biol. 31:195-221.

302. Edelman, G.M. (1985) Specific cell adhesion in histogenesis and morphogenesis. In

The Cell in Contact: Adhesions and Junctions as Morphogenetic Determinants, G.M. Edelman and J.-P. Thiery, eds., pp. 139-168, Wiley, New York.

303. Edelman, G.M. (1985) Neural Darwinism: Population thinking and higher brain

function. In How We Know, Michael Shafto, ed., pp. 1-30, Harper and Row, San Francisco.

304. Crossin, K.L. and Edelman, G.M. (1986) Mechanisms of cell adhesion in epithelial-

mesenchymal transformations. In Cellular Endocrinology: Hormonal Control of Embryonic and Cellular Differentiation, G. Serrero and J. Hayashi, eds., pp. 81-92, Alan R. Liss, New York.

305. Crossin, K.L., Hoffman, S., Grumet, M., Thiery, J.-P., and Edelman, G.M. (1986) Site-

restricted expression of cytotactin during development of the chicken embryo. J. Cell Biol. 102:1917-1930.

306. Daniloff, J.K., Levi, G., Grumet, M., Rieger, F., and Edelman, G.M. (1986) Altered

expression of neuronal cell adhesion molecules induced by nerve injury and repair. J. Cell Biol. 103:929-945.

307. Daniloff, J.K., Chuong, C.-M., Levi, G., and Edelman, G.M. (1986) Differential

distribution of cell adhesion molecules during histogenesis of the chick nervous system. J. Neurosci. 6:739-758.

308. Edelman, G.M. (1986) Evolution and morphogenesis: The regulator hypothesis. In

17th Stadler Genetics Symposium on Genetics, Development and Evolution, G.P. Gustafson, ed., pp. 1-28, Plenum Press, New York.

309. Edelman, G.M. (1986) Cell adhesion molecules in the regulation of animal form and

tissue pattern. Annu. Rev. Cell Biol. 2:81-116.

Gerald M. Edelman Bibliography 310. Edelman, G.M. (1986) Cell adhesion molecules in neural histogenesis. Ann. Rev.

Physiol. 48:417-430. 311. Edelman, G.M. (1986) Molecular mechanisms of morphologic evolution. In Molecular

Evolution of Life, Chemica Scripta, Vol. 26B, H. Baltscheffy, H. Jornvall and R. Rigler, eds., pp. 363-375, Cambridge University Press, Cambridge.

312. Edelman, G.M. (1986) Profits and Prophecy: A Partial View of American Science

Near the Millenium. In American Society: Public and Private Responsibilities, W. Knowlton and R. Zeckhauser, eds., pp. 223-248, Harper & Row, New York.

313. Friedlander, D.R., Grumet, M., and Edelman, G.M. (1986) Nerve growth factor

enhances expression of neuron-glia cell adhesion molecule in PC12 cells. J. Cell Biol. 102:413-419.

314. Gallin, W.J., Chuong, C.-M., Finkel, L.H., and Edelman, G.M. (1986) Antibodies to

liver cell adhesion molecule perturb inductive interactions and alter feather pattern and structure. Proc. Natl. Acad. Sci. USA 83:8235-8239.

315. Hemperly, J.J., Edelman, G.M., and Cunningham, B.A. (1986) cDNA clones of N-

CAM lacking a membrane-spanning region consistent with evidence for membrane attachment via a phosphatidylinositol intermediate. Proc. Natl. Acad. Sci. USA 83:9822-9826.

316. Hemperly, J.J., Murray, B.A., Edelman, G.M., and Cunningham, B.A. (1986)

Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM. Proc. Natl. Acad. Sci. USA 83:3037-3041.

317. Hoffman, S., Friedlander, G., Chuong, C.-M., and Edelman, G.M. (1986) Differential

contributions of Ng-CAM and N-CAM to cell adhesion in different neural regions. J. Cell Biol. 103:145-158.

318. Murray, B.A., Hemperly, J.J., Prediger, E.A., Edelman, G.M., and Cunningham,

B.A.(1986) Alternatively spliced mRNAs code for different polypeptide chains of the chicken neural cell adhesion molecule (N-CAM). J. Cell Biol. 102:189-193.

319. Murray, B., Owens, G., Prediger, E.A., Crossin, K.L, Cunningham, B.A., and

Edelman, G.M. (1986) Cell Surface modulation of the neural cell adhesion molecule resulting from alternative mRNA splicing in a tissue-specific developm-ental sequence. J. Cell Biol. 103:1431-1439.

320. Reeke, G.N., Jr. and Edelman, G.M. (1986) Recognition Automata Based on

Selective Neural Networks. In Structure and Dynamics of Nucleic acids, Proteins, and Membranes, E. Clementi and S. Chin, eds., pp. 329-353, Plenum Press, New York.

Gerald M. Edelman Bibliography 321. Rieger, F., Daniloff, J.K., Pinçon-Raymond, M., Crossin, K.L, Grumet, M., and

Edelman, G.M. (1986) Neuronal cell adhesion molecules and cytotactin are colocalized at the node of Ranvier. J. Cell Biol. 103:379-391.

322. Chuong, C.-M., Crossin, K.L., and Edelman, G.M. (1987) Sequential expression and

differential function of multiple adhesion molecules during the formation of cerebellar cortical layers. J. Cell Biol. 104:331-342.

323. Crossin, K.L. and Edelman, G.M. (1987) Molecular regulation of neural morphogen-

esis. In University of Michigan Symposium From Message to Mind: Directions in Developmental Neurobiology, Sinauer Publications.

324. Cunningham, B.A., Hemperly, J.J., Murray, B.A., Prediger, E.A., Brackenbury, R.,

and Edelman, G.M. (1987) Neural cell adhesion molecule: Structure, immunoglobulin-like domains, cell surface modulation and alternative RNA splicing. Science 236:799-806.

325. Duband, J.-L., Dufour, S., Hatta, K., Takeichi, M., Edelman, G.M., and Thiery, J.-P.

(1987) Adhesion molecules during somitogenesis in the avian embryo. J. Cell Biol. 104:1361-1374.

326. Edelman, G.M. and Gallin, W.J. (1987) Cell adhesion as a basis of pattern in

embryonic development. Am. Zool. 27:645-656. 327. Edelman, G.M. and Gallin, W.J. (1987) Cell adhesion in the regulation of pattern and

structure during feather induction. In Banbury Report 26: Developmental Toxicology: Mechanisms and Risks., pp. 109-121, Cold Spring Harbor, New York.

328. Edelman, G.M., Murray, B.A., Mege, R.M., Cunningham, B.A., and Gallin, W.J. (1987)

Cellular expression of liver and neural cell adhesion molecules after transfection with their cDNAs results in specific cell-cell binding. Proc. Natl. Acad. Sci. USA 84:8502-8506.

329. Edelman, G.M. (1987) CAMs and Igs: Cell adhesion and the evolutionary origins of

immunity. Immunological Reviews 100:11-45. 330. Finkel, L.H. and Edelman, G.M. (1987) Population rules for synapses in networks. In

Synaptic Function, G.M. Edelman, W.E. Gall, and W.M. Cowan, eds., Wiley, New York.

331. Finkel, L.H., and Edelman, G.M. (1987) Computer simulations of dynamic functional

changes in the topographic maps of adult animals. In IEEE Conference on Neural Information Processing Systems - Natural and Synthetic.

Gerald M. Edelman Bibliography 332. Gallin, W.J., Sorkin, B.C., Edelman, G.M., and Cunningham, B.A. (1987) Sequence

analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM. Proc. Natl. Acad. Sci. USA 84:2808-2812.

333. Hoffman, S. and Edelman, G.M. (1987) A proteoglycan with HNK-1 antigenic

determinants is a neuron-associated ligand for cytotactin. Proc. Natl. Acad. Sci. USA 84:2523-2527.

334. Levi, G., Crossin, K.L., and Edelman, G.M. (1987) Expression sequences and

distribution of two primary cell adhesion molecules during embryonic development of Xenopus laevis. J. Cell Biol. 105:2359-2372.

335. Owens, G.C., Edelman, G.M., and Cunningham, B.A. (1987) Organization of the N-

CAM gene: Alternative exon usage as the basis for different membrane-associated domains. Proc. Natl. Acad. Sci. USA 84:294-298.

336. Pearson, J.C., Finkel, L.H., and Edelman, G.M. (1987) Plasticity in the organization of

cerebral cortical maps: A computer simulation based on neuronal group selection. J. Neurosci. 7:4209-4223.

337. Reeke, G.N., Jr. and Edelman, G.M. (1987) Selective neural networks and their

implications for recognition automata. The International Journal of Supercomputer Applications 1:44-69.

338. Richardson, G., Crossin, K.L., Chuong, C.-M., and Edelman, G.M. (1987) Expression

of cell adhesion molecules during embryonic induction III. Development of the otic placode. Dev. Biol. 119:217-230.

339. Tan, S.S., Crossin, K.L., Hoffman, S., and Edelman, G.M. (1987) Asymmetric

expression in somites of cytotactin and its proteoglycan ligand is correlated with neural crest cell distribution. Proc. Natl. Acad. Sci. USA 84:7977-7981.

340. Crossin, K.L., Richardson, G.P., Chuong, C.-M., and Edelman, G.M. (1988)

Modulation of adhesion molecules during induction and differentiation of the auditory placode. In Auditory Function: Neurological Bases of Hearing, G.M. Edelman, W.E. Gall, and W.M. Cowan, eds., pp. 93-112, John Wiley & Sons, New York.

341. Edelman, G.M., Mege, R.-M., and Tan, S.-S. (1988) Regulation of tissue form and

function by adhesion molecules during epithelial-mesenchymal transforamtions. In Molecular Mimicry in Health and Disease, Å. Lernmark, T. Dyrberg, L. Terenius, and B. Hökfelt, eds., pp. 83-94, Elsevier Science Publishers, The Netherlands.

342. Edelman, G.M. (1988) Morphoregulatory Molecules. Perspec. Biochem. 27:3533-

3543.

Gerald M. Edelman Bibliography 343. Fraser, S.E., Carhart, M.S., Murray, B.A., Chuong, C.-M., and Edelman, G.M. (1988)

Alterations in the Xenopus retinotectal projection by antibodies to Xenopus N-CAM. Dev. Biol. 129:217-230.

344. Friedlander, D.R., Hoffman, S., and Edelman, G.M. (1988) Functional Mapping of

Cytotactin: Proteolytic Fragments Active in Cell-Substrate Adhesion. J. Cell Biol. 107:2329-2340.

345. Grumet, M. and Edelman, G.M. (1988) Neuron-glia cell adhesion molecule interacts

with neurons and astroglia via different binding mechanisms. J. Cell Biol. 106:487-503.

346. Hoffman, S., Crossin, K.L., and Edelman, G.M. (1988) Molecular forms, binding

functions and developmental expression patterns of cytotactin and CTB proteoglycan, an interactive pair of extracellular matrix molecules. J. Cell Biol. 106:519-532.

347. Jones, F.S., Burgoon, M.P., Hoffman, S., Crossin, K.L., Cunningham, B.A., and

Edelman, G.M. (1988) A cDNA clone for cytotactin contains sequences similar to epidermal growth factor-like repeats and segments of fibronectin and fibrinogen. Proc. Natl. Acad. Sci. USA 85:2186-2190.

348. Mege, R.M., Matsuzaki, F., Gallin, W.J., Goldberg, J.I., Cunningham, B.A., and

Edelman, G.M., (1988) Construction of epitheloid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proc. Natl. Acad. Sci. USA 85:7274-7278.

349. Prediger, E.A., Hoffman, S., Edelman, G.M., and Cunningham, B.A. (1988) Four

exons encode a 93-base-pair insert in three neural cell adhesion molecule mRNAs specific for chicken heart and skeletal muscle. Proc. Natl. Acad. Sci. USA 85:9616-9620.

350. Raphael, Y., Volk, T., Crossin, K.L., Edelman, G.M., and Geiger, B. (1988) The

modulation of cell adhesion molecule expression and intercellular junction formation in the developing avian inner ear. Dev. Biol. 128:222-235.

351. Reeke, G.N., Jr. and Edelman, G.M. (1988) Real brains and artificial intelligence.

Daedalus 117:143-173. 352. Reeke, G.N., Jr. and Edelman, G.M. (1988) Selective networks and recognition

automata. In Advances in Cognitive Science. Steps Toward Convergence, AAAS Selected Symposium 104, M. Kochen and H.M. Hastings, eds., pp. 50-71, American Association for the Advancement of Science, Washington, D.C.

Gerald M. Edelman Bibliography 353. Reeke, G.N., Jr. and Edelman, G.M. (1988) Recognition automata based on Neural

Darwinism. In Forefronts, Cornell University, Center for Theory and Simulation in Science and Engineering, Ithaca, New York, Vol. 3, No. 12, pp. 3-6, April 1988.

354. Rieger, F., Nicolet, M., Pinçon-Raymond, M., Levi, G., Murawsky, M., and Edelman,

G.M. (1988) Distribution and role in regeneration of N-CAM in basal laminae of muscle and Schwann cells. J. Cell Biol. 107:707-719.

355. Sorkin, B.C., Hemperley J.J., Edelman, G.M., and Cunningham, B.A. (1988) Structure

of the gene for the liver cell adhesion molecule, L-CAM. Proc. Natl. Acad. Sci. USA 85:7617-7621.

356. Becker, J.W., Erickson, H.P, Hoffman, S., Cunningham, B.A., and Edelman, G.M.

(1989) Topology of cell adhesion molecules. Proc. Natl. Acad. Sci. USA 86:1088-1092.

357. Crossin, K.L., Hoffman, S., Tan, S.-S., and Edelman, G.M. (1989) Cytotactin and its

proteoglycan ligand mark structural and functional boundaries in the somatosensory cortex of the early postnatal mouse. Dev. Biol. 136:381-392.

358. Crossin, K.L. and Edelman, G.M. (1989) Adhesion molecules in pattern formation and

neural histogenesis. In From Reading to Neurons, A.M. Galaburda, ed., pp. 475-502, MIT Press, Cambridge.

359. Daniloff, J.K., Crossin, K.L., Pinçon-Raymond, M., Murawsky, M., Rieger, F., and

Edelman, G.M. (1989) Expression of cytotactin in the normal and regenerating neuromuscluar system. J. Cell Biol. 108:625-635.

360. Edelman, G.M. (1989) Topobiology. Scientific American 260:5:76-88. 361. Finkel, L.H. and Edelman, G.M. (1989) The integration of distributed cortical systems

by reentry: a computer simulation of interactive functionally segregated visual areas. J. Neurosci. 9(9):3188-3208.

362. Finkel, L.H., Reeke, G.N., Jr., and Edelman, G.M. A population approach to the

neural basis of perceptual categorization. In Neural Connections, Mental Computation, L. Nadel, L.A. Cooper, P. Culicover, and R.M. Harnish, eds., pp. 146-179, Bradford Books, MIT Press, Cambridge (1989).

363. Friedlander, D.R., Mège, R.M., Cunningham, B.A., and Edelman, G.M. (1989) Cell

sorting-out is modulated by both the specificity and amount of different cell adhesion molecules (CAMs) expressed on cell surfaces. Proc. Natl. Acad. Sci. USA 86:7043-7047.

364. Hoffman, S., Crossin, K.L., Jones, F.S., Friedlander, David R., and Edelman, G.M.

(1989) Cytotactin and cytotactin-binding proteoglycan: an interactive pair of

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365. Jones, F.S., Hoffman, S., Cunningham, B.A. and Edelman, G.M. (1989) A detailed

structural model of cytotactin: Protein homologies, alternative RNA splicing, and binding regions. Proc. Natl. Acad. Sci. USA 86:1905-1909.

366. Mackie, K., Sorkin, B.C., Nairn, A.C., Greengard, P., Edelman, G.M., and

Cunningham, B.A. (1989) Identification of two protein kinases that phosphorylate the neural cell adhesion molecule, N-CAM, J. Neurosci., Vol. 9, No. 6:1883-1896.

367. Prieto, A.L., Crossin, K.L., Cunningham, B.A., and Edelman, G.M. (1989) Localization

of mRNA for N-CAM polypeptides in neural and nonneural tissues by in situ hybridization. Proc. Natl. Acad. Sci. USA 86:9579-9583.

368. Reeke, G.N., Jr., Sporns, O., and Edelman, G.M. (1989) Synthetic Neural Modeling:

comparisons of population and connectionist approaches. In Proceedings of a Conference, Connectionism in Perspective, R. Pfeifer, ed., pp. 113-139, Elsevier Science Publishing Co. Inc., Amsterdam.

369. G.N. Reeke, Jr., Finkel, L.H., Sporns, O., and Edelman, G.M. (1989) Synthetic neural

modeling: A multilevel approach to the analysis of brain complexity. In Signal and Sense: Local and Global Order in Perceptual Maps. G.M. Edelman, W.E. Gall, and W.M. Cowan, eds., Wiley, New York.

370. Sporns, O., Gally, J.A., Reeke, G.N., and Edelman, G.M. (1989). Reentrant signaling

among simulated neuronal groups leads to coherency in their oscillatory activity. Proc. Natl. Acad. Sci. USA 86:7265-7269.

371. Brackenbury, R., and Edelman, G.M. (1989) Expression of cell adhesion molecules

during embryogenesis and malignancy. In Proceedings of the UCLA Symposia Conference on Tumor Progression and Metastasis. Isaiah J. Fidler and Garth L. Nicholson, eds., Series editor, C. Fred Fox.

372. Begemann, M., Tan, S.S., Cunningham, B.A., and Edelman, G.M. (1990) Expression

of chicken liver cell adhesion molecule fusion genes in transgenic mice. Proc. Natl. Acad. Sci. USA 87:9042-9046.

373. Burgoon, M.P., Grumet, M., Mauro, V., Edelman, G.M., and Cunningham, B.A. (1990)

Structure of the chicken neuron-glia cell adhesion molecule, Ng-CAM: Origin of the polypeptides and relation to the Ig superfamily. J. Cell Biol. 112:1017-1029.

374. Edelman, G.M. and Reeke, G.N., Jr. (1990) Is it possible to construct a perception

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Artificial Parallel Computation, J.A. Robinson and M. Arbib, eds., The MIT Press, Cambridge, Mass.

376. Gally, J., Montague, P.R., Reeke, G.N., and Edelman, G.M. (1990) The NO

hypothesis: possible effects of a short-lived rapidly diffusible signal in the development and function of the nervous system. Proc. Natl. Acad. Sci. USA. 87:3547-3551.

377. Hoffman, S., Crossin, K.L., and Edelman, G.M. (1990) Coordinate expression and

function of cytotactin and its proteoglycan ligand. In Morphoregulatory Molecules, G.M. Edelman, B.A. Cunningham, and J.-P. Thiery, eds., pp. 259-282, Wiley, New York.

378. Jaffe, S.H., Friedlander, D.R., Matsuzaki, F., Crossin, K.L., Cunningham, B.A., and

Edelman, G.M. (1990) Differential effects of the cytoplasmic domains of cell adhesion molecules on cell aggregation and sorting out. Proc. Natl. Acad. Sci. USA. 87:3589-3593.

379. Jones, F.S., Crossin, K.L., Cunningham, B.A., and Edelman, G.M. (1990)

Identification and characterization of the promoter for the cytotactin gene. Proc. Natl. Acad. Sci. USA. 87:6497-6501.

380. Matsuzaki, F., Mege, R.M., Jaffe, S.H., Friedlander, D.R., Gallin, W.J., Goldberg, J.I.,

Cunningham, B.A., and Edelman, G.M. (1990) cDNAs of cell adhesion molecules of different specificity induce changes in cell shape and border formation in cultured S180 cells. J. Cell Biol. 110:1239-1252.

381. Prieto, A.L., Jones, F.S., Cunningham, B.A., Crossin, K.L., and Edelman, G.M. (1990)

Localization during development of alternatively spliced forms of cytotactin mRNA by in situ hybridization. J. Cell Biol. 111:685-698.

382. Reeke G.N., Jr., Finkel, L.H., and Edelman, G.M. (1990) Selective recognition

automata. In An Introduction to Neural and Electronic Networks, S.F. Zornetzer, J.L. Davis, and C. Lau, eds., pp. 203-226, Academic Press, Orlando.

383. Reeke, G.N., Jr., Sporns, O., and Edelman, G.M. (1990) Synthetic Neural Modeling:

The "Darwin" Series of Recognition Automata. Proc. IEEE. 78(9):1498-1530. 384. Edelman,G.M. and Cunningham, B.A. (1990) Place-dependent cell adhesion,

process retraction, and spatial signalling in neural morphogenesis. In Cold Spring Harbor Symposium on Quantatative Biology: "The Brain" 55:303-318.

385. Musil, L.S., Cunningham, B.A., Edelman, G.M., and Goodenough, D.A. (1990)

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines. J. Cell Biol. 111:2077-2088.

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and figure-ground segregation by means of active reentrant connections. (Gestalt) Proc. Natl. Acad. Sci. USA 88:129-133.

387. Edelman, G.M. and Crossin, K.L. (1991) Cell adhesion molecules in neural

morphogenesis. In Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission. K. Fuxe and L.F. Agnati, eds., Raven Press, Ltd., New York.

388. Grumet, M., Mauro, V., Burgoon, M.P., Edelman, G.M., and Cunningham, B.A. (1991)

Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules. J. Cell Biol. 113:1399-1412.

389. Williamson, D.A., Parrish, E.P., and Edelman, G.M. (1991) Distribution and

expression of two interactive extracellular matrix proteins, cytotactin and cytotactin-binding proteoglcan, during development of Xenopus laevis. I. Embryonic Development. J. Morphol. 209:189-202.

390. Williamson, D.A., Parrish, E.P., and Edelman, G.M. (1991) Distribution and

Expression of Two Interactive Extracellular Matrix Proteins, Cytotactin and Cytotactin-Binding proteoglycan, During Development of Xenopus laevis.

II. Metamorphosis. J. Morphol. 209:203-213. 391. Sporns, O., Tononi, G., and Edelman, G.M. (1991) Dynamic interactions of neuronal

groups and the problem of cortical integration. In Nonlinear Dynamics and Neural Networks: Proceedings of the 63rd W.E. Heraeus Seminar, H.G. Schuster, ed., pp. 205-317, VCH Publishers, FRG.

392. Montague, P.R., Gally, J.A., and Edelman, G.M. (1991) Spatial Signaling in the

development and function of neural connections. Cerebral Cortex 1:199-220. 393. Edelman, G.M., and Crossin, K.L. (1991) Cell Adhesion Molecules: Implications for a

Molecular Histology. Annu. Rev. Biochem. 60:155-90. 394. Finkel, L.H., Reeke, G.N. Jr., and Edelman, G.M. (1991) A cortically based model for

integration in visual perception. In Neural Networks for Human and Machine Perception, Volume 1, H. Wechsler, ed., pp.41-63, Academic Press, New York.

395. Reeke, G.N., Finkel, L.H., Sporns, O., and Edelman, G.M. (1991) Synthetic neural

modeling: A multilevel approach to the analysis of brain complexity. In Signal and Sense: Local and Global Order in Perceptual Maps, Chapter 24, p.p. 607-707, Wiley, New York, 1990.

396. Powell, S.K., Cunningham, B.A., Edelman, G.M., and Rodriguez-Boulan, E. (1991)

Targeting of transmembrane and GPI-anchored forms of N-CAM to opposite domains of a polarized epithelial cell. Nature 353:76-77.

Gerald M. Edelman Bibliography 397. Sorkin, B.C., Gallin, W.J., Edelman, G.M., and Cunningham, B.A. (1991) Genes for

two calcium-dependent cell adhesion molecules have similar structures and are arranged in tandem in the chicken genome. Proc. Natl. Acad. Sci. USA 88:11545-11549.

398. Edelman, G.M. (1992) Morphoregulation. Dev. Dynam. 193:2-10. 399. Jones, F.S., Prediger, E.A., Bittner, D.A., DeRobertis, E.M., and Edelman, G.M.

(1992) Cell adhesion molecules as targets for hox genes: Neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proc. Natl. Acad. Sci. USA. 89:2086-2090.

400. Jones, F.S., Chalepakis, G., Gruss, P., and Edelman, G.M. (1992) Activation of the

cytotactin promoter by the homeobox-containing gene Evx-1. Proc. Natl. Acad. Sci. USA. 89:2091-2095.

401. Gally, J.A., and Edelman, G.M. (1992) Evidence for gene conversion in genes for cell

adhesion molecules. Proc. Natl. Acad. Sci. USA. 89:3276-3279. 402. Tononi, G., Sporns, O., and Edelman, G.M. (1992) The problem of neural integration:

Induced rhythms and short-term correlations. In Induced Rhythms, E. Basar and T. Bullock, eds., pp. 367-396, Birkhauser, Boston.

403. Schwanzel-Fukuda, S., Abraham, S., Crossin, K.L., Edelman, G.M., and Pfaff, D.W.

(1992) Immunocytochemical demonstration of neural cell adhesion molecule (N-CAM) along the migration route of luteinizing hormone-releasing hormone (LHRH) neurons in mice. J. Comp. Neurol. 321:1-18.

404. Hanbauer, I., Wink D., Osawa, Y., Edelman, G.M., and Gally, J.A. (1992) Role of

nitric oxide in NMDA-evoked release of [3H]-dopamine from striatal slices. NeuroReport 3:409-412.

405. Tononi, G., Sporns, O., and Edelman, G.M. (1992) Reentry and the problem of

integrating multiple cortical areas: Simulation of dynamic integration in the visual system. Cerebral Cortex 2:310-335.

406. Edelman, G.M., Reeke, G.N., Gall, W.E., Tononi, G., Williams, D., and Sporns, O.

(1992) Synthetic neural modeling applied to a real-world artifact. Proc. Natl. Acad. Sci. USA 89:7267-7271.

407. Edelman, G.M. (1992) Linking Brain to Behavior: Value and selection in neural

populations. In Proceedings of the Course on Neuropsychology: The Neuronal Basis of Cognitive Function, Fidia Research Foundation, pp. 55-66, Thieme Medical Publishers, Inc., New York.

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brain. Proc. Natl. Acad. Sci. USA. 89:11651-11652. 409. Edelman, G.M., and Jones, F.S. (1992) Cytotactin: A morphoregulatory molecule and

a target for regulation by homebox gene products. Trends Biochem. Sci. 17:228-32.

410. Mauro, V. P., Krushel, L.A., Cunningham, B.A., and Edelman, G.M. (1992)

Homophilic and heterophilic binding activities of Nr-CAM, a nervous system cell adhesion molecule. J. Cell Bio. 119:191-202.

411. Edelman, G.M. (1992) Mediation and inhibition of cell adhesion by morphoregulatory

molecules. Cold Spring Harbor Symposium Quantatative Biology. 57:317-25. 412. Crossin, K.L. and Edelman, G.M. (1992) Specific binding of cytotactin to sulfated

glycolipids. J. Neurosci. Res. 33:631-638. 413. Edelman, G.M. (1993) Neural Darwinism: Selection and reentrant signaling in higher

brain function. Neuron 10:115-125. 414. Shiga, T., Shirai, T., Grumet, M., and Edelman, G.M. (1993) Differential expression

of neuron-glia cell adhesion molecule (Ng-CAM) on developing axons and growth cones of interneurons in the chick embryo spinal cord: an immunoelectron microscopic study. J. Compar. Neurol. 329:512-518.

415. Krushel, L.A., Prieto, A.L., Cunningham, B.A., and Edelman, G.M. (1993) Expression

patterns of the cell adhesion molecule Nr-CAM during histogenesis of the chick nervous system. Neuroscience 53:797-812.

416. Grumet, M., Friedlander, D.R., and Edelman, G.M. (1993) Evidence for the binding of

Ng-CAM to laminin. Cell Adh. and Comm. 1:177-190. 417. Edelman, G.M. (1993). A golden age for adhesion. Cell Adh. and Comm. 1:1-7. 418. Jones, F.S., Holst, B.D., Minowa, O., De Robertis, E.M., and Edelman, G.M. (1993).

Binding and transcriptional activation of the promoter for the N-CAM adhesion molecule HoxC6 (Hox3.3), Proc. Natl. Acad. Sci. USA 90:6557-6561.

419. Edelman, G.M. (1993) Adhesion and counteradhesion: morphogenetic functions of

the cell surface. In Progress in Brain Research, Vol. 101, Proceedings of Nobel Symposium 83, L. Svennerholm, A.K. Ashbury, R.A. Reisfeld, K. Sandloff, K. Suzuki, G. Tetttamanta and G. Tuffano, eds., pp. 1-14, Elsevier Science Publishers, Amsterdam.

420. Edelman, G.M., and Jones, F.S. (1993) Outside and downstream of the homeobox.

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attachment to cytotactin/tenascin. Proc. Natl. Acad. Sci. USA 90:10154-10158. 422. Schwanzel-Fukuda, M., Reinhard, G.R., Abraham, S., Crossin, K.L., Edelman, G.M.,

and Pfaff, D.W. (1993) Antibody to neural cell adhesion molecule can disrupt the migration of lutenizing hormone-releasing hormone neurons into the mouse brain. J. Comp. Neurol. 342:174-185.

423. Sporns, O., and Edelman, G.M. (1993) Solving Bernstein's problem: A proposal for

the development of coordinated movement by selection. Child Development 64: 960-981.

424. Friston, K.J., Tononi, G., Reeke, G.N., Jr., Sporns, O., and Edelman, G.M. (1994)

Value-dependent selection in the brain: Simulation in a synthetic neural model. Neuroscience 59(2):229-243.

425. Sorkin, B.C., Jones, F.S., Cunningham, B.A., and Edelman, G.M. (1993) Identification

of the promoter and a transcriptional enhancer of the gene encoding L-CAM, a calcium-dependent cell adhesion molecule. Proc. Natl. Acad. Sci. USA 90:11356-11360.

426. Sporns, O., Tononi, G, and Edelman, G.M. (1993) Correlated neuronal activity and

behavior. In Proceedings of the International Conference on Artificial Neural Networks, ICANN "93, S. Gielen and B. Kappen, eds., pp. 125-130, Springer-Verlag, London.

427. Mauro, V.P., Wood, I.C., Krushel, L., Crossin, K.L., and Edelman, G.M. (1994) Cell

adhesion alters gene transcription in chicken embryo brain cells and mouse embryonal carcinoma cells. Proc. Natl. Acad. Sci. USA 91:2868-2872.

428. Tononi, G., Sporns, O., and Edelman, G.M. (1994) A measure for brain complexity:

Relating functional segregation and integration in the nervous system. Proc. Natl. Acad. Sci. USA 91:5033-5037.

429. Krushel, L., Prieto, A.L., Edelman, G.M., and Crossin, K.L. (1994) Differential effect

of cytotactin fusion protein on intracellular pH and cell morphology. J. Cell Physiol. 161: 508-518.

430. Goomer, R.S., Holst, B.D., Wood, I.C., Jones, F.S., and Edelman, G.M. (1994)

Regulation in vitro of an L-CAM enhancer by homeobox genes Hox D9 and HNF-1. Proc. Natl. Acad. Sci. USA 91:7985-7989.

431. Holst, B.D., Goomer, R.S., Wood, J.C., Edelman, G.M., and Jones, F.S. (1994)

Binding and activation of the promoter for the neural cell adhesion molecule (N-CAM) by Pax-8. J. Biol. Chem. 269(35):22245-22252.

Gerald M. Edelman Bibliography 432. Chalepakis, G., Jones, F.S., Edelman, G.M., and Gruss, P. (1994) Pax-3 contains

domains for transcription activation and transcription inhibition. Proc. Natl. Acad. Sci. USA 91:12745-12749.

433. Edelman, G.M. (1994) The evolution of somatic selection: The antibody tale. Genetics

138:975-981. 434. Edelman, G.M. (1994) Adhesion and counteradhesion: morphogenetic functions of

the cell surface. Biological Function of Gangliosides, Elsevier Science Ltd., Chapter 1, London, England.

435. Reeke, G.N.,Jr., Sporns, O., Gall, W.E., Tononi, G., and Edelman, G.M. (1994) A

biologically based synthetic nervous system for a real-world device. In Artificial Neural Networks for Speech and Vision, R.J. Mammone, ed., pp. 457-473. Chapman and Hall, London.

436. Reeke, G.N., Jr., Finkel, L.H., and Edelman, G.M. (1995) Selective recognition

automata. In An Introduction to Neural and Electronic Networks, 2nd edition, S.F. Zornetzer, J.L. Davis, C. Lau, T. McKenna, eds., Chapter 11, Academic Press, San Diego.

437. Sporns, O., Tononi, G., and Edelman, G.M. (1994) Neural models of cortical

integration. In Advances in Functional Neuroimaging: Technical Foundations, R.W. Thatcher, M. Hallet, T. Zeffiro, E.R. John, and M. Huerta eds., pp. 1-7, Academic Press, San Diego.

438. Copertino, D.W., Jenkinson, S., Jones, F.S., and Edelman, G.M. (1995) Structural

and functional similarities between the promoters for mouse tenascin and chicken cytotactin. Proc. Natl. Acad. Sci. USA 92:2131-2135.

439. Sporns, O., Edelman, G.M., and Crossin, K.L. (1995) The neural cell adhesion

molecule (N-CAM) inhibits proliferation in primary cultures of rat astrocytes. Proc. Natl. Acad. Sci. USA 92:542-546.

440. Krushel, L.A., Sporns, O., Cunningham, B.A., Crossin, K.L., and Edelman, G.M.

(1995) Neural cell adhesion molecule (N-CAM) inhibits astrocyte proliferation after injury to different regions of the adult rat brain. Proc. Natl. Acad. Sci. USA 92:4323-4327.

441. Frick, I.-M., Crossin, K.L., Edelman, G.M., and Björck, L. (1995) Protein H – A

bacterial surface protein with affinity for both immunoglobulin and fibronectin type III domains. EMBO J. 14(8):1674-9.

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system. In Nature's Imagination: The Frontiers of Scientific Vision. J. Cornwell, ed., pp. 78-100, Oxford University Press.

443. Edelman, G.M. (1995) Memory and the individual soul: against silly reductionism. In

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444. Burgoon, M.P., Hazan, R.B., Phillips, G., Crossin, K.L., Edelman, G.M., and

Cunningham, B.A. (1995) Functional analysis of post-translational cleavage products of the neuron-glia CAM, Ng-CAM. J. Cell Biol. 130(3):733-744.

445. Reeke, G.N.,Jr., and Edelman, G.M. (1995) Darwinist view of the prospects for

conscious artifacts. In Consciousness: Distinction & Reflection, G. Trautteur, ed., pp. 106-130, Bibliopolis, Naples, Italy.

446. Phillips, G.R., Edelman, G. M., and Crossin, K.L. (1995) Separate cell binding sites

within cytotactin/tenascin differentially promote neurite outgrowth. Cell Adh. Comm. 3:257-271.

447. Verschure, P.F.M.J., Wray, J., Sporns, O., Tononi, G. and Edelman, G.M. (1995)

Multilevel analysis of classical conditioning in a behaving real world artifact: An illustration of synthetic neural modeling. J. Robotics and Autonomous Systems 16:247-265.

448. Edelman, G.M., and Jones, F.S. (1995) Developmental control of N-CAM expression

by hox and pax gene products. In Evolution of Eukaryotic Cellular Processes, Proceedings of the Royal Society Symposium, Philosophical Transaction B, 349:305-312.

449. Edelman, G.M., and Jones, F.S. (1995) Developmental control of neural cell

adhesion. In Challenges and Perspectives in Neuroscience. Ottoson, D., Bartfai, T., Hokfelt, T., Fuxe, K. (Eds.). Proceedings of the Wenner-Gren Center International Conference, Elsevier Science Ltd., London, England, pp. 79-99.

450. Kallunki, P., Jenkinson, S., Edelman, G.M., and Jones, F.S. (1995) Silencer elements

modulate the expression of the gene for the Ng-CAM. J. Biol. Chem., 270:21291-21298.

451. Friston, K.J., Tononi, G., Sporns, O., and Edelman, G.M. (1995) Characterising the

complexity of neuronal interactions. Human Brain Mapping, 3:302-314.

452. Wang, Y., Jones, F.S., Krushel, L.A., and Edelman, G.M. (1996) Embryonic expression patterns of the N-CAM gene are regulated by homeodomain binding sites. Proc. Natl. Acad. Sci. USA, 93:1892-1896.

Gerald M. Edelman Bibliography 453. Tranque, P., Crossin, K.L., Cirelli, C., Edelman, G.M., and Mauro, V.P. (1996)

Identification and characterization of a RING-finger gene (C-RZF) expressed in chicken embryo cells. Proc. Natl. Acad. Sci. USA, 93:3105-3109.

454. Tononi, G., Sporns, O., and Edelman, G.M. (1996) A complexity measure for

selective matching of signals by the brain. Proc. Natl. Acad. Sci. USA, 93:3422-3427.

455. Edelman, G.M., and Tononi, G. (1996) Selection and development: The brain as a

complex system. In The Lifespan Development of Individuals, D. Magnusson, ed., pp. 179-204, Cambridge University Press, New York.

456. Wang, Y., Krushel, L.A., and Edelman, G.M. (1996) Targeted DNA recombination in

vivo using an adenovirus carrying the Cre recombinase gene. Proc. Natl. Acad. Sci. USA, 93:3932-3936.

457. Ranheim, T.S., Edelman, G.M., and Cunningham, B.A. (1996) Homophilic adhesion

mediated by the neural cell adhesion molecule N-CAM involves multiple immunoglobulin domains. Proc. Natl. Acad. Sci. USA, 93:4071-4075.

458. Sporns, O., Tononi, G., and Edelman, G.M. (1996) Reentry and dynamical

interactions of cortical networks. In Models of Neural Networks II, J.L. van Hemmen, E. Domany, and K. Schulten, eds., pp. 315-341, Springer-Verlag, New York.

459. Wray, J., and Edelman, G.M. (1996) A model of color vision based on cortical reentry.

Cerebral Cortex, 6:701-716. 460. Edelman, G.M. (1996) Gene knockout by viral delivery. Nature Biotechnology,

14:1537. 461. Mauro, V.P., Edelman, G.M. (1996) rRNA-like sequences occur in diverse primary

transcripts: implications for the control of gene expression. Proc. Natl. Acad. Sci. USA, 94:422-247.

462. Holst, B.D., Wang, Y., Jones, F.S., Edelman, G.M. (1996) A binding site for Pax

proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord. Proc. Natl. Acad. Sci. USA, 94:1465-1470.

463. Copertino, D.W., Edelman, G.M., Jones, F.S. (1997) Multiple promoter elements

differentially regulate the expression of the mouse tenascin gene. Proc. Natl. Acad. Sci. USA, 93:1846-1851.

464. Jones, F.S., Kioussi, C., Copertino, D.W., Kallunki, P., Holst, B.D., Edelman, G.M.

(1997) Barx2, a new homeobox gene of the Bar class, is expressed in neural and


craniofacial structures during development. Proc. Natl. Acad. Sci. USA, 94:2632-2637.

465. Crossin, K.L., Tai, M.-H., Krushel, L.A., Mauro, V.P., Edelman, G.M. (1997)

Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation. Proc. Natl. Acad. Sci. USA, 94:2687-2692.

466. Lumer, E.D., Edelman, G.M., and Tononi, G. (1997) Neural dynamics in a model of

the thalamcortical system. I. Layers, loops and the emergence of fast (20-60 Hz) synchronous rhythms. Cerebral Cortex, 7:207-227.

467. Lumer, E.D., Edelman, G.M., and Tononi, G. (1997) Neural dynamics in a model of

the thalamocortical system. II. The role of neural synchrony tested through perturbations of spike timing. Cerebral Cortex, 7:228-236.

468. Rucci, M., Tononi, G., Edelman, G.M. (1997) Registration of neural maps through

value-dependent learning: modeling the alignment of auditory and visual maps in the barn owl's optic tectum. J. Neurosci., 17:334-352.

469. Edelman, G.M., Tononi, G. (1997) Neural Darwinism: A selectionist view of the brain.

In, Der Mensch und sein Gehirn, D. Ploog, ed., pp.187-233, Siemens Foundation/Serie Paper, Piper Munchen, Zurich.

470. Kallunki, P., Edelman, G.M., Jones, F.S. (1997) Tissue-specific expression of the L1

cell adhesion molecule is modulated by the neural restrictive silencer element. J. Cell Biol., 138:1343.

471. Holst, B.D., Vanderklish, P.W., Krushel, L.A., Zhou, W., Langdon, R.B., McWhirter,

J.R., Edelman, G.M., Crossin, K.L. (1998) Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM. Proc. Natl. Acad. Sci. USA, 95:2597-2602.

472. Krushel, L.A., Tai, M-H., Cunningham, B.A., Edelman, G.M., Crossin, K.L. (1998)

Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation. Proc. Natl. Acad. Sci. USA, 95:2592-2596.

473. Tononi, G., Srinivasan, R., Russell, D.P., Edelman, G.M. (1998) Investigating neural

correlates of conscious perception by frequency-tagged neuromagnetic responses. Proc. Natl. Acad. Sci. USA, 95:3198-3203.

474. Kallunki, P., Edelman, G.M., Jones, F.S. (1998) The neural restrictive silencer

element can act as both a repressor and enhancer of L1 cell adhesion molecule gene expression during postnatal development. Proc. Natl. Acad. Sci. USA, 95:3233-3238.

Gerald M. Edelman Bibliography 475. Edelman, G.M. (1998) Building a picture of the brain. Daedalus, 127:37-69. 476. Tononi, G., McIntosh, A.R., Russell, D.P., Edelman G.M. (1998) Functional

clustering: Identifying strongly interactive brain regions in neuroimaging data. NeuroImage, 7:138-149.

477. Almassy, N., Edelman, G.M., Sporns, O. (1998) Behavioral constraints in the

development of neuronal properties: A cortical model embedded in a real-world device. Cerebral Cortex, 8:346-361.

478. Edelman, G.M., Jones, F.S. (1998) Gene regulation of cell adhesion: a key step in

neural morphogenesis. Brain Res. Reviews, 26:337-352. 479. Tononi, G. and G.M. Edelman (1998) Consciousness and the integration of

information in the brain. Advances in Neurology, 77:245-280. 480. Little, E.B., Edelman, G.M. and Cunningham, B.A. (1998) Palmitoylation of the

cytoplasmic domain of the neural cell adhesion molecule N-CAM serves as an anchor to cellular membranes. Cell Adhesion and Communication, 6:415-430.

481. Tononi, G., Edelman, G.M. and Sporns, O. (1998) Complexity and coherency:

integrating information in the brain. Trends in. Cog. Scien., 2:474-484. 482. Tononi, G. and Edelman, G.M. (1998) Consciousness and complexity. Science,

282:1846-1851. 483. Tranque, P., Hu, M.C.-Y, Edelman, G.M. and Mauro, V.P. (1998) rRNA

complementarity within mRNAs: A possible basis for mRNA-ribosome interactions and translational control. Proc. Natl. Acad. Sci. USA, 95:12238-12243.

484. Sporns, O., Edelman, G.M. (1998) Bernstein’s dynamic view of the brain: The current

problems of modern neurophysiology (1945). Motor Control, 2:283-305. 485. Krushel, L.A., Cunningham, B.A., Edelman, G.M. and Crossin, K.L. (1999) NF-κB

activity is induced by neural cell adhesion molecule binding to neurons and astrocytes. J. Biol. Chem. 274:2432-2439.

486. Hu, M.C.-Y., Tranque, P., Edelman, G.M. and Mauro, V.P. (1999) rRNA-

complementarity in the 5' UTR of mRNA specifying the Gtx homeodomain protein: evidence that base-pairing to 18S rRNA affects translational efficiency. Proc. Natl. Acad. Sci. USA, 96:1339-1344.

487. Rucci, M., Edelman, G.M. and Wray, J. (1999) Adaption of orienting behavior: From

the barn owl to a robotic system. IEEE Trans. Robotics and Automation, 15:96-110.

Gerald M. Edelman Bibliography 488. Meech, R., Kallunki, P., Edelman, G.M. and Jones, F.S. (1999) A binding site for

homeodomain and Pax proteins is necessary for L1 cell adhesion molecule gene expression by Pax-6 and bone morphogenetic proteins. Proc. Natl. Acad. Sci. USA, 96:2420-2425.

489. Tononi, G., O. Sporns, and Edelman, G.M., (1999) Measures of degeneracy and

redundancy in biological networks. Proc. Natl. Acad. Sci. USA 96:3257-3262. 490. Atkins, A., Osborne, M., Lashuel, A. H., Edelman, G.M., Wright, E., P., Cunningham,

A. B., and Dyson, H. J., (1999) Association between the first two immunoglobulin-like domains of the neural cell adhesion molecule N-CAM. FEBS Letters, 451 162-168.

491. Srinivasan, R., Russell, D.P., Edelman, G.M., Tononi, G. (1999) Increased

synchronization of neuromagnetic responses during conscious perception. J. Neurosci, 19:5435-5448.

492. Rucci, M., Edelman, G.M., Wray, J. (2000) Robust localization of auditory and visual

targets in a robotic barn owl. J. Rob. Auton. Syst. 30:181-193. 493. Sporns, O., Tononi, G., Edelman, G.M. (2000) Theoretical neuroanatomy: relating

anatomical and functional connectivity in graphs and cortical connection matrices. Cerebral Cortex 10:127-141.

494. Koenigsberger, C., Chicca, J.J. (II), Amoureux, M.C., Edelman, G.M., Jones, F.S.

(2000) Differential regulation by multiple promoters of the gene encoding the neuron-restrictive silencer factor (NRSF/REST). Proc. Natl. Acad. Sci. USA, 97:2291-2296.

495. Vanderklish, P.W., Krushel, L.A., Holst, B.H., Gally, J.A., Crossin, K.L., Edelman,

G.M. (2000) Marking synaptic activity in dendritic spines with a calpain substrate exhibiting fluorescence resonance energy transfer. Proc. Natl. Acad. Sci. USA, 97:2253-2258.

496. Edelman, G.M., Meech, R., Owens, G.C., Jones, F.S. (2000) Synthetic promoter

elements obtained by nucleotide sequence variation and selection for activity. Proc. Natl. Acad. Sci. USA, 97:3038-3043.

497. Amoureux, M.C., Cunningham, B.A., Edelman, G.M., Crossin, K.L. (2000) N-CAM

binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype. J. Neurosci, 20:3631-3640.

498. Chappell, S.A., Edelman, G.M., Mauro, V.P. (2000) A 9-nt segment of a cellular

mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity. Proc. Natl. Acad. Sci. USA, 97:1536-1541.

Gerald M. Edelman Bibliography 499. Sporns, O., Tononi, G., Edelman, G.M. (2000) Connectivity and complexity; the

relationship between neuroanatomy and brain dynamics. Neural Networks, 13:909-922.

500. Tononi, G., Edelman, G.M. (2000) Schizophrenia and the mechanisms of conscious

integration. Brain Res. Reviews, 31:391-400. 501. Krichmar, J., Snook, J., Edelman, G.M. (2000) Experience-dependent perceptual

categorization in a behaving real-world device. Intl. Conf. Cog. Nrl. Sys. Pro. 502. Zhou, W., Edelman, G.M., Mauro, V.P. (2001) Transcript leader regions of two

Saccharomyces cerevisiae mRNAs contain internal ribosome entry sites that function in living cells. Proc. Natl. Acad. Sci. USA, 98:1531-1536.

503. Little, E.B., Crossin, K.L., Krushel, L.A., Edelman, G.M., Cunningham, B.A. (2001) A

short segment within the cytoplasmic domain of the neural cell adhesion molecule (N-CAM) is essential for N-CAM induced NF-κB activity in astrocytes. Proc. Natl. Acad. Sci. USA, 98:2238-2243.

504. Owens, G.C., Chappell, S.A., Mauro, V.P., Edelman, G.M. (2001) Identification of two

short internal ribosome entry sites selected from libraries of random oligonucleotides. Proc. Natl. Acad. Sci. USA, 98:1471-1476.

505. Pinkstaff, J.K., Chappell, S.A., Mauro, V.P., Edelman, G.M., Krushel, L.A. (2001)

Internal initiation of translation of five dendritically-localized neuronal mRNAs. Proc. Natl. Acad. Sci. USA, 98:2770-2775.

506. Atkins, A.R., Chung, J., Deechongkit, SP., Little, E.B., Edelman, G.M., Wright, P.E.,

Cunningham, B.A., Dyson, H.J. (2001) Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: Can solution studies define the mechanism of homophilic binding? J. Mol. Biol., 311:161-172.

507. Edelman, G.M. (2001) Consciousness: The remembered present. Ann. N.Y. Acad.

Sci., 929:111-122. 508. Edelman, G.M., Gally, J.A. (2001) Degeneracy and complexity in biological systems.

Proc. Natl. Acad. Sci. USA, 98:13763-13768. 509. Schmitt-Ulms, G., Legname, G., Baldwin, M.A., Ball, H.L., Brandon, N., Bosque, P.J.,

Crossin, K.L., Edelman, G.M., DeArmond, S.J., Cohen, F.E., Prusiner, S.B. (2001) Binding of Neural Cell Adhesion Molecules (N-CAMs) to the Cellular Prion Protein. J. Mol. Biol. 314:1209-1225.

Gerald M. Edelman Bibliography 510. Mistry, S.K., Keefer, E.W., Cunningham, B.A., Edelman, G.M., Crossin, K.L. (2002)

Cultured rat hippocampal neural progenitors generate spontaneously active neural networks. Proc. Natl. Acad. Sci. USA, 99:1621-1626.

511. Vanderklish, P.W., Edelman, G.M. (2002) Dendritic spines elongate after stimulation

of group 1 metabotropic glutamate receptors in cultured hippocampal neurons. Proc. Natl. Acad. Sci. USA, 99:1639-1644.

512. Yin, Y., Edelman, G.M., Vanderklish, P.W. (2002) The brain-derived neurotrophic

factor enhances synthesis of Arc in synaptoneurosomes. Proc. Natl. Acad. Sci. USA, 99:2368-2373.

513. Owens, G.C., Mistry, S., Edelman, G.M., Crossin, K.L. (2002) Efficient marking of

neural stem cell-derived neurons with a modified murine embryonic stem cell virus, MESV2. Gene Therapy, 9:1044-1048.

514. Mauro, V.P., Edelman, G.M. (2002) The ribosome filter hypothesis. Proc. Natl. Acad.

Sci. USA, 99:12031-12036. 515. Krichmar, J.L., Edelman, G.M. (2002) Machine Psychology: Autonomous behaviour,

perceptual categorization and conditioning in a brain-based device. Cerebral Cortex, 12:818-830.

516. Sporns, O., Tononi, G., Edelman, G.M. (2002) Theoretical neuroanatomy and the

connectivity of the cerebral cortex. Behav. Brain Res., 135:69-74. 517. Zhou, W., Edelman, G.M., Mauro, V.P. (2003) Isolation and identification of short

nucleotide sequences that affect translation initiation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA, 100:4457-4462.

518. Edelman, G.M. (2003) Naturalizing consciousness: A theoretical framework. Proc.

Natl. Acad. Sci. USA, 100:5520-5524. 519. Chen, Y., Seth, A.K., Gally, J.A., Edelman, G.M. (2003) The power of human brain

magnetoencephalographic signals can be modulated up or down by changes in an attentive visual task. Proc. Natl. Acad. Sci. USA, 100:3501-3506.

520. Smart, F.M., Edelman, G.M., Vanderklish, P.W. (2003) BDNF induces translocation of

initiation factor 4E to mRNA granules: Evidence for a role of synaptic microfilaments and integrins. Proc. Natl. Acad. Sci. USA, 100:14403-14408.

521. Edelman, G.M. (2004) Biochemistry and the sciences of recognition. J. Biol. Chem.,

279:7361-7369.

Gerald M. Edelman Bibliography 522. Rogers, G.W. Jr., Edelman, G.M., Mauro, V.P. (2004) Differential utilization of

upstream AUGs in the β-secretase mRNA suggests that a shunting mechanism regulates translation. Proc. Natl. Acad. Sci. USA, 101:2794-2799.

523. Mauro, V.P., Edelman, G.M., Zhou, W. (2004) Reevaluation of the conclusion that

IRES-activity reported within the 5’ leader of the TIF4631 gene is due to promoter activity. RNA, 10:895-597.

524. Chappell, S.A., Edelman, G.M., Mauro, V.P. (2004) Biochemical and functional

analysis of a 9-nt RNA sequence that affects translation efficiency in eukaryotic cells. Proc. Natl. Acad. Sci. USA, 101:9590-9594.

525. Izhikevich, E.M., Gally, J.A., Edelman, G.M. (2004) Spike-timing dynamics of

neuronal groups. Cereb. Cortex, 14:933-944. 526. Salbaum, J.M., Cirelli, C., Walcott, E., Krushel, L.A., Edelman, G.M., Tononi, G.

(2004) Chlorotoxin-mediated disinhibition of noradrenergic locus coeruleus neurons using a conditional transgenic approach. Brain Res., 1016:20-32.

527. Gally, J.A., Edelman, G.M. (2004) Neural reapportionment: an hypothesis to account

for the function of sleep. C.R. Biologies, 327:721-727. 528. Seth, A.K., McKinstry, J.L., Edelman, G.M., Krichmar, J.L. (2004) Visual binding

through reentrant connectivity and dynamic synchronization in a brain-based device. Cereb. Cortex, 14:1185-1199.

529. Atkins, A.R., Gallin, W.J., Owens, G.C., Edelman, G.M. (2004) Neural cell adhesion

molecule (N-CAM) homophilic binding mediated by the two N-terminal Ig domains is influenced by intramolecular domain-domain interactions. J. Biol. Chem., 279:49633-49643.

530. Seth, A.K., McKinstry, J.L., Edelman, G.M., Krichmar, J.L. (2004) Active sensing of

visual and tactile stimuli by brain-based devices. International Journal of Robotics and Automation, 19:222-238.

531. Dresios, J., Aschrafi, A., Owens, G.C., Vanderklish, P.W., Edelman, G.M., Mauro,

V.P. (2005) Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis. Proc. Natl. Acad. Sci. USA, 102:1865-1870.

532. Krichmar, J.L., Nitz, D.A., Gally, J.A., Edelman, G.M. (2005) Characterizing functional

hippocampal pathways in a brain-based device as it solves a spatial memory task. Proc. Natl. Acad. Sci. USA, 102:2111-2116.

533. Aschrafi, A., Cunningham, B.A., Edelman, G.M., Vanderklish, P.W. (2005) The fragile

X mental retardation protein and group I metabotropic glutamate receptors


regulate levels of mRNA granules in brain. Proc. Natl. Acad. Sci. USA, 102:2180-2185.


Non-Scientific "Occasional Papers" 1. Edelman, G.M. (1986) Profits and Prophecy: A partial view of American Science near

the millenium: In American Society: Public and Private Responsibilities. W. Knowlton, R. Zeckhauser, eds., Chapter 10, pp. 223-248, Ballinger Pub. Co., Cambridge, MA.

2. Edelman, G.M. (1995) The wordless metaphor: visual art and the brain. Whitney

Museum Catalogue, K. Kertess, ed., pp. 33-47.Edelman, G.M. (1995) Bright air, brilliant fire: Neurobiology and the mind." In Neuroscience, Memory, and Language, Vol. 1, Decade of the Brain, National Institute of Mental Health, ed., Neuroscience and the Philosophy of the Mind, pp. 3-9, Library of Congress, Washington D.C.

3. Edelman, G.M. (2004) Interview with Gerald M. Edelman: part I. Adam Wilkins,

Editor. Bioessays, 26:204-213. 4. Edelman, G.M. (2004) Interview with Gerald M. Edelman: part II. Adam Wilkins,

Editor. Bioessays, 26:326-335.

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