arro case: ductal cell carcinoma in situ · 2014-10-14 · arro contour ductal carcinoma in-situ...

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ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia, PA

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Page 1: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

ARRO Contour Ductal Carcinoma In-Situ

Talha Shaikh, MD

Faculty Advisor: Shelly Hayes, MD

Fox Chase Cancer Center

Philadelphia, PA

Page 2: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

Radiation Dose

• Whole Breast Dose: 50 Gy in 2 Gy fractions

• Tumor Bed Boost: 10 Gy in 2 Gy fractions

Page 3: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

Radiation Planning

• CT Simulation

– Supine with arms up on a 15-20 degree breast board

• Goal is to bring sternum parallel to the table

– Wire palpable breast tissue, clinical breast borders and lumpectomy incision

• Medial border mid sternum

• Lateral border 2 cm lateral to palpable breast tissue (mid axillary line)

• Inferior border 2 cm below the inframammary fold

• Superior border head of the clavicle or 2nd intercostal space

Page 4: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

Treatment Volumes

• GTV: Surgical cavity from lumpectomy. Contour using all available clinical and radiographic information including the cavity volume, lumpectomy scar, seroma and surgical clips

• CTV: Takes into account clinical borders at the time of CT simulation. Generally, posteriorly to the anterior surface of the chest wall

• Medial border mid sternum

• Lateral border 2 cm lateral to palpable breast tissue (mid axillary line)

• Inferior border 2 cm below the infra-mammary fold

• Superior border head of the clavicle or 2nd intercostal space

Page 5: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

Treatment Volumes • PTV: Breast CTV + 7 mm expansion

– Used for beam aperture generation

• PTV-EVAL: Clipped 5 mm into skin anteriorly and no deeper than the anterior surface of the ribs posteriorly (excludes boney thorax and lung)

– Used for DVH analysis

Page 6: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 7: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 8: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 9: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 10: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 11: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 12: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 13: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 14: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 15: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL

Page 16: ARRO Case: Ductal Cell Carcinoma in Situ · 2014-10-14 · ARRO Contour Ductal Carcinoma In-Situ Talha Shaikh, MD Faculty Advisor: Shelly Hayes, MD Fox Chase Cancer Center Philadelphia,

GTV CTV PTV

PTV-EVAL