annual report of resej'rch facility (type or … · o180·doa·an 1) professionally acceptable...

19
This report is reqUIred by law (7 USC 2143). Failure to report according to the regulations can result in an order 10 cease and desist and to be subject 10 penalties as provided for ,n Section 2150 See reverse side for additional information Interagency Report Control No o180·DOA·AN 1) ProfeSSionally acceptable standard" govermng the care, treatment, and use of ammals, Indudlng appropriate use of anesthetiC, analgeSIC, and tranqUilizing drugs, pMr to, dUring, and following actual research, testing, surgery, or experimentation were followed by this research facility. 2) Each principal Inveshgator has com"dered alternatives ':0 painful procedures. 3} This facility is adhering to the stand3rds and regulations under the Act. and it has required that exceptions to the standards and regulations be specified and explained by the prinCipal inveshgalor and approved by the Institutional ,mimal Care and Use Committee (IACUC). A summary of all the exceptions Is attached to this annual report. In addition to identifying the IAGUC·approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected. 4) The attending velennarian for this "'search facility has appropriate aUlhonty to ensure the provision of adequate vetefinary care and to oversee the adequacy of other aspects of animal care and use UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. , FORM APPROVED f<&t.. ANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0001 48 OMB NO. 0579-0036 2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA, ANNUAL REPORT OF RESEJ'RCH FACILITY include Zip Code) (TYPE OR PRINT) YALE UNIVERSITY 1 HILLHOUSE AVENUE PO BOX 208365 NEW HAVEN, CT 06520 (203) 785-2525 3. REPORTING FACILITY (Ust alilocatie,ns where animals were housed or used in actual research, testing, teaching, or experimentation, or held for these purposes. Attach additional sheets if necessary.) FACILITY LOCATIONSlsites) See Attached Listing REPORT OF ANIMALS USED BY OR UNlIER CONTROL OF RESEARCH FACILITY (Attach addnlOnal sheets if necessary or use APHiS FORM 7023A) A. B. Numberof C. Number of D. Number of animals upon E, Number of animals upon which teaching, F. animals being anirrals upon which experiments, experiments, research, surgery or tests were Anirrnls Covered bred. which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO. By The Ani mal c(lnditioned, or research. surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS Welfare Regulations hHld for use In experiments, or conducted involving anesthetic,analgesic, or tranquilizing drugs would teaching, testing, tests were accompanying pain or have adversely affected the procedures, results. or (Cols.C + e):perlments, conducted distress to the animals interpretation of the teaching, researCh, D+ E) research, Dr involving no and for which appropriate experiments. surgery, or tests. (An explanation of surgery but not pain, distress. or anesthetic, analgesic, or the procedures producing pain or distress in these used for such use of pain- tranquiliZing drugs were an;mals and the reasons such drugs were not used purposes. relieving drugs used. must be attached to this report) 1 21 21 4. Dogs 5. Cats 13 13 6. Guinea Pigs 1 96 21 117 7 Hamsters 578 64 642 8. Rabbits 23 162 185 18 112 37 149 9. Non-Human Primates 10. Sheep 2 1 8 9 3 3 45 48 11. Pigs 12. Other Farm Animals Goat 9 9 13. Other Animals Ferrets 290 34 324 Mastomy 28 Peromyscus 64 37 37 ASSURANCE STATEMENTS ,. CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL (Chief Executive Officer or Legally Responsible Institutional official) I certify that the above is true, correct, and complete (7 U.S.C. Section 2143) S DATE SIGNED ,,/-z.fJ/ot- APHIS FORM 7023 (AUG 91) (Replaces VS FORM 18·2:1 (Oct 88), which Is obsolete PART1-HEADQUARTERS

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This report is reqUIred by law (7 USC 2143). Failure to report according to the regulations canresult in an order 10 cease and desist and to be subject 10 penalties as provided for ,n Section 2150

See reverse side foradditional information

Interagency Report Control Noo180·DOA·AN

1) ProfeSSionally acceptable standard" govermng the care, treatment, and use of ammals, Indudlng appropriate use of anesthetiC, analgeSIC, and tranqUilizing drugs, pMr to, dUring,and following actual research, teac~ling, testing, surgery, or experimentation were followed by this research facility.

2) Each principal Inveshgator has com"dered alternatives ':0 painful procedures.

3} This facility is adhering to the stand3rds and regulations under the Act. and it has required that exceptions to the standards and regulations be specified and explained by theprinCipal inveshgalor and approved by the Institutional ,mimal Care and Use Committee (IACUC). A summary of all the exceptions Is attached to this annual report. Inaddition to identifying the IAGUC·approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending velennarian for this "'search facility has appropriate aUlhonty to ensure the provision of adequate vetefinary care and to oversee the adequacy of otheraspects of animal care and use

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. , FORM APPROVED f<&t..ANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0001 48 OMB NO. 0579-0036

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA,ANNUAL REPORT OF RESEJ'RCH FACILITY include Zip Code)

(TYPE OR PRINT) YALE UNIVERSITY1 HILLHOUSE AVENUE PO BOX 208365

NEW HAVEN, CT 06520

(203) 785-2525

3. REPORTING FACILITY (Ust alilocatie,ns where animals were housed or used in actual research, testing, teaching, or experimentation, or held for these purposes. Attach additionalsheets if necessary.)

FACILITY LOCATIONSlsites)

See Attached Listing

REPORT OF ANIMALS USED BY OR UNlIER CONTROL OF RESEARCH FACILITY (Attach addnlOnal sheets if necessary or use APHiS FORM 7023A)

A. B. Numberof C. Number of D. Number of animals upon E, Number of animals upon which teaching, F.animals being anirrals upon which experiments, experiments, research, surgery or tests were

Anirrnls Covered bred. which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO.By The Ani mal c(lnditioned, or research. surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations hHld for use In experiments, or conducted involving anesthetic,analgesic, or tranquilizing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, results. or (Cols.C +e):perlments, conducted distress to the animals interpretation of the teaching, researCh, D+ E)research, Dr involving no and for which appropriate experiments. surgery, or tests. (An explanation ofsurgery but not pain, distress. or anesthetic, analgesic, or the procedures producing pain or distress in theseYf~t used for such use of pain- tranquiliZing drugs were an;mals and the reasons such drugs were not usedpurposes. relieving drugs used. must be attached to this report)

1 21 214. Dogs

5. Cats 13 13

6. Guinea Pigs 1 96 21 117

7 Hamsters 578 64 642

8. Rabbits 23 162 185

18 112 37 1499. Non-Human Primates

10. Sheep 2 1 8 9

3 3 45 4811. Pigs

12. Other Farm Animals

Goat 9 9

13. Other Animals

Ferrets 290 34 324

Mastomy 28

Peromyscus 64 37 37

ASSURANCE STATEMENTS,.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

S ~NALOFFICIAL DATE SIGNED ,,/-z.fJ/ot-~

APHIS FORM 7023(AUG 91)

(Replaces VS FORM 18·2:1 (Oct 88), which Is obsolete PART1-HEADQUARTERS

ThiS report is required by law (7 USC: 2143). Failure to report according to the regulations canresult In an order to cease and desist and to be subjeclllO penalties as provided for in Section 2150

See reverse side foradditional information.

Interagency Report Control No0180-DOA-AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO.

I FORM APPROVEDANIMAL ANO PLMT HEALTH INSPECTION SERVICE 16-R-0001 48OMS NO. 057g·0036

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered wUh USDA,CONTINUATION StlEET FOR ANNUAL REPORT inc/ude Zip Code)

OF RESI:ARCH FACILITY YALE UNIVERSITY1 HILLHOUSE AVENUE PO BOX 208365

(TYPE OR PRINT) NEW HAVEN, CT 06520(203) 785-2525

REPORT OF ANIMALS USED BY OR UNDER CONTROL 01= RESEARCH FACILITY (Attach addUional sheets if necessary or use this form)

A. B. Numberof C. Number of D. Number of animals upon E. Number of animals upon which teaching, F.animals being animals upon which experiments, experiments, research, surgery or tests were

Anomals Covered tred, which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO.By The Animal conditioned, or research, surgery, or tests were to the animais and for which the use of appropnate OF ANIMALS

Welfare RegulallDns held for use in experiments, or conducted involv'lng anesthetic,analgesic, or tranquHizing drugs wouldt',aching, tesling. tests were accompanying pain or have adversely affected the procedures, results, or (Cols. C +Experiments. conducted distress to the animals Interpretation of the teaching, research, D+ E)rl~search, or involving no and for which appropriate experiments. surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthetic, analgesic, or the procedures prodUcing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were no/ used~urposes. relieVing drugs. used. must be attached to this reporl)

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.........r--...

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ASSURANCE STATEMENTS

1) ProfeSSionally acceptable standarcs governing the carl3, treatment, and use of anHnals. Including approprrate use of anesthetiC, analgeSIC. and tranquilizing drugs, prior to. dUring,and follOWing actual research, teaching, testing, surgery. or experimentation were followed by this research facility.

2) Each principai investigator has considered alternalives to painful procedures.

3) ThiS facility IS adhering to the standards and reguiations under the Act. and It has required that except'lons to the standards and regulations be specified and explained by Iheprincipal investigator and approvec by Ihe Institutional Animal Care and Use Committee (IACUC). A summary of all the exceptions Is attached to this annual report. Inaddition to Identifying lhe IACUC-aoproved exceplions, Ih,s summary includes a brief explanation of the exceptions, as weil as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority 10 ensure the provision of adequate veterinary care and 10 oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief E~xecutiveOfficer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.s.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

APHIS FORM 7023A(AUG 91)

(Replaces VS FORM 1S-23 (Oct 88). which Is obsolete PART 1 - HEADQUARTERS

October 1, 2006 - September 30, 2007Explanation for IACUC Approved Exceptions to USDA RegulationsYale University 16-R-0001

Feeding

Seventeen Macaca mulatta, Category C, underwent food regulation to motivatelearning. Animals were given a reduced ration of monkey chow during thetesting period of up to five days per week. During this time, their diets weresupplemented by food rewards earned during testing and by food treats given aspart of the enrichment program. The investigator and the veterinary staffmonitored the animals' health status. Daily assessments included bodycondition, food consumption, behavior, and hydration status. Animals wereweighed weekly and returned to full feed when not on study. Animals did notexhibit any overt discomfort or distress.

Watering

Three Macaca mulattC!,. Category C, and seven Macaca mulatta, Category D,underwent water regulation to enhance performance and motivation to learn andperform complex tasks. Fluid intake was sufficient to maintain the animals'health and well-being. It was accomplished by permitting the animals to earnfluid to satiety each day during behavioral training and testing, providing adlibitum chow and treats and stopping fluid regulation when animals were not onstudy. Daily assessments included body condition, food consumption, behavior,and hydration status. Animals were weighed weekly and did not exhibit any overtdiscomfort or distress.

,hiS report i~ required by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 21!

See attached form foradditional information.

Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0003 FORM APPROVED

ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036CUSTOMER NUMBER: 49

lJ l: I UH ()f)(r

~I. (

Wesleyan UniversityANNUAL REPORT OF RESEARCH FACILITY Vice Pres Academic Affairs &Provost

( TYPE OR PRINT) 237 High StreetMiddletown, CT 06459

Telephone: (860) -685-2010

3. REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, or experimentation, or held for these purposes. Attach additional sheets if necessary ) IFACILITY LOCATIONS ( Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY { Attach additional sheets if necessarY or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, accompanying pain or distress to the animals and for wh

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were the use of appropriate anesthetic, analgesic, or tranquilizOF ANIMALSBy The Animal teaching, testing, experiments, or conducted involving drugs would have adversely affected the procedures, res

Welfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,research, or conducted distress to the animals an surgery, or tests. (An explanation of the procedures ( COLUMNS

surgery but not ye involVing no pain, for which appropriate producing pain or distress in these animals and the reas( C+D+E)used for such distress, or use 0 anesthetic, analgesic, or such drugs were not used must be attached to this reportpurposes. pain-relieving tranquilizing drugs were

drugs. used.-- -_._----I--

/'-

4. Dogs

- ---5. Cats /'-- ---

/'6. Guinea Pigs

----,-,------- -

/'7. Hamsters-----, - -----

/'-

8. Rabbits

------ -

9. Non-human Primates \\SXV- -

10. Sheep ,'~~--~_. -

11 Pigs ;QX-~/--

12. Other Farm Animals ,,~----- ,('\

;/,/

-----

13. Other Animals /--------_.._-f----/"

_._-------

I ASSURANCE STATEMENTS I1) Professionally acceptable standards governing the care, treatment, and use of animals. including appropnate use of anestetlc, analgesIc, and tranqUiliZing drugs, pnor to, dUring, and following actual rest

teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS facility is adhering to the standards and regulations under the Act, and it has reqUired that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Committee (IACUC). A summary of all such exceptions is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy o{ other aspects of animal care and use.

APHIS FORM 7023

(AUG91 )

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

ef Executive Officer or Legally Responsible Institutional Official)

NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print)

(Replaces VS FORM 18-23 (OCT 88), which is obsolete.)

DATE SIGNED

(V' ,)~O

This report is required by law (7 USC 2143). Failure to report according to the regulations can See reverse side forresult In an order to cease and desist and to be subject to penalties as provided for in Section 2150 additional information

Interagency Report Control No0180-DOA-AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. IANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0007 51 FORM APPROVED

OMB NO. 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY(TYPE OR PRINT)

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as regisfered with USDA,

include Zip Code) ;<t-HARTFORD HOSPITAL80 SEYMOUR STREET- P.O. BOX 5037HARTFORD, CT 06102

13.

REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, teaching, or expenmentation, or held for these purposes. Attach additionalsheets if necessary.)

FACILITY LOCATIONS( t )8/ es

ANIMAL RESEARCH FACILITYHARTFORD, CT 06102

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use APHIS FORM 7023A)

A. B. Number of C. Number of D. Number of animals upon E. Number of animals upon which teaching. F.animals being animals upon which experiments, experiments, research, surgery or tests were

Animals Covered bred, which teaching, teaching, research, conducted involVing accompanying pain or distress TOTAL NO.By The Animal conditioned, or research, surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involving anesthetic,analgesic. or tranquilizing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, results, or (Cols. C +experiments, conducted distress to the animals interpretation of the teaching, research, D + E)research, or involving no and for which appropriate experiments, surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthellc, analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs. used. must be attached to this report)

4. Dogs 4 12 12

5. Cats

6 Guinea Pigs

7. Hamsters

8 Rabbits

9. Non-Human Primates

10 Sheep 3 3

11 Pigs 109 109

12. Other Farm Animals

13. Other Animals

ASSURANCE STATEMENTS

1) Professionally acceptable standards governing the care, treatment, and use of anImals, Including appropnate use of anesthetic, analgesIc, and tranquIlizing drugs, pnor to, dunng,and following actual research, teaching, testing, surgery, or experlmentallon were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS facility is adhenng to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by theprinCipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of all the exceptions is attached to this annual report. Inaddilion to identifying the IACUC-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

10101/2007

APHIS FORM 7023(AUG 91)

(Replaces VS FORM 18·23 (Oct 88), which IS obsolete PART1-HEADQUARTERS

This report IS required by law (7 USC 2143). Failure to report according to the regulations can See reverse side forresult In an order to cease and desist and to be subject to penalties as provided for in Section 2150 additional information

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. IANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0008 52

Interagency Report Control No0180-DOA-AN

FORM APPROVED ,jIOMB NO. 0579-0036 I\J'-

ANNUAL REPORT OF RESEARCH FACILITY(TYPE OR PRINT)

2. HEADQUARTERS RESEARCH FACILITY (Name and Address. as registered with USDA,include Zip Code)

UNIVERSITY OF CONNECTICUT438 WHITNEY RD EXT. UNIT 1006. WHETTEN GRAD CTR

STORRS, CT 06269-1006

REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, teaching, or experimentation, or held for these purposes. Attach additionalsheets ',f necessary.)

FACILITY LOCATIONS( fl )s es

UNIVERSITY OF CONNECTICUT

STORRS, CT 06269-1133

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use APHIS FORM 7023A)

A. B. Number of C. Number of D. Number of animals upon E. Number of animals upon which teaching, F.animals being animals upon which experiments, experiments, research, surgery or tests were

Animals Covered bred, which teaching, teaching, research, conducted involVing accompanying pain or distress TOTAL NO.By The Animal conditioned, or research, surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involving anesthetic,analgesic, or tranqUiliZing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, results, or (CoIs. C +experiments, conducted distress to the animals interpretation of the teaching, research, D + E)research, or involving no and for which appropriate experiments, surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthetic, analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranqUiliZing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs. used. must be attached to this report)

4. Dogs 24 24

5. Cats 4 8 8

6. Guinea Pigs 40 40

7. Hamsters

8. Rabbits 85 166 88 254

9. Non-Human Primates

10. Sheep 39 39

11. Pigs

12. Other Farm Animals

13. Other Animals

Mole Rats 352 65 4 69

ASSURANCE STATEMENTS

1) Professionally acceptable standards governing the care, treatment, and use of animals, including appropnate use of anesthetiC, analgesIc, and tranqUiliZing drugs, pnor to, dunng,and folloWing actual research, teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by theprincipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of att the exceptions is attached to this annual report. Inaddition to identifying the lAGUe-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E,O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

11/28/2007

APHIS FORM 7023(AUG 91)

(Replaces VS FORM 18-23 (Oct 88), which IS obsolete PART1·HEADQUARTERS

This report is required by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 21'

See attached form foradditional information.

Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0011 FORM APPROVED; f1I,-ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036

CUSTOMER NUMBER: 43

University Of HartfordANNUAL REPORT OF RESEARCH FACILITY 200 Bloomfield Avenue

(TYPE OR PRINT) West Hartford, CT 06117

Telephone: (860) -768-4544

3. REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, or experimentation, or held for these purposes. Attach additionat sheets if necessary ) IFACILITY LOCATIONS ( Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY ( Attach additional sheets if necessarv or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, accompanying pain or distress to the animals and for wh

TOTAL NUMBERAnimals Covered held for use in research. surgery, or tests were the use of appropriate anesthetic, analgesic, or tranquilizOF ANIMALSBy The Animal teaching, testing, experiments, or conducted involving drugs would have adversely affected the procedures, res

Welfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,research, or conducted distress to the animals an surgery, or tests. (An explanation of the procedures ( COLUMNSsurgery but not yE involving no pain, for which appropriate producing pain or distress in these animals and the reas( C+D+E)used for such distress, or use 0 anesthetic, analgesic, or such drugs were not used must be attached to this repor1purposes. pain-relieving tranquilizing drugs were

drugs. used.-----_..~-

4. Dogs (j 0 (:) D ()5. Cats

0 0 0 0-----7)

6. Guinea Pigs (:) () 1"') D 0-------7. Hamsters () y, 0 (:> 08. Rabbits 0 (-~ 0 {) (')

9. Non-human Primates 0 () 0 D n-

10 Sheep 0 () C- D 0------

11 Pigs 0 rJ /'- . () 6-------- .'./

12. Other Farm Animals b 0 0 () (J

-- -----

13 Other Animals D (,;;, 0 0 0----------

I---------

I ASSURANCE STATEMENTS I1) Professionally acceptable standards governing the care, treatment, and use of animals, Including appropriate use of anestetlc, analgesIc, and tranquilizing drugs, prior to, dUring, and following actual res,

teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS facility is adhering to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Committee (IACUC). A summary of all such exceptions is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

.)

NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print)

DATE SIGNED

This report IS required by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 21'

See attached form foradditional information.

~Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0015 FORM APPROVED

ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579·0036CUSTOMER NUMBER: 812

Trinity CollegeANNUAL REPORT OF RESEARCH FACILITY 300 Summit Street

( TYPE OR PRINT) Hartford, CT 06106

Telephone: (860) -297-2000

3. REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing. or experimentation. or held for these purposes. Attach additional sheets if necessary ) IFACILITY LOCATIONS ( Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY I Attach additional sheets if necessarv or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, accompanying pain or distress to the animals and for wh

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were the use of appropriate anesthetic, analgesic, or tranquilizOF ANIMALS

By The Animal teaching, testing, experiments, or conducted involving drugs would have adversely affected the procedures, resWelfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,

research, or conducted distress to the animals an surgery, or tests. (An explanation of the procedures ( COLUMNSsurgery but not yE involving no pain, for which appropriate producing pain or distress in these animals and the reas( C+D+E)used for such distress, or use n anesthetic, analgesic, or such drugs were not used must be attached to this reportpurposes. pain-relieving tranquilizing drugs were

drugs. used.--

4. Dogs 0 () () b05. Cats 0 0 () 006. Guinea Pigs D () 0 () ()-------------

7. Hamsters 0 0 (") (")0-----

8. Rabbits 0 " n 0 09. Non-human Primates 0 0 () () 010. Sheep 0 0 0 f) 0----~-

11. Pigs0 D () 0 0

12. Other Farm Animals 0 () 0 F"l (!)--_.

13. Other Animals0 D 0 00

~--------

-

I ASSURANCE STATEMENTS I1) Professionally acceptable standards governing the care, Ireatment, and use of anrmals, Including approprrate use of anestetlc, analgesic, and tranquiliZing drugs, prior to, during, and following actual reSE

teaching, testing, surgery, or experimentation were followed by Ihis research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adherrng to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Committee (IACUC). A summary of all such exceptions is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of anrmals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

DATE SIGNED

Re.t\~ r(fk~ef\ \IPAcode~c

This report is required by law (7 USC 2143). Failure to report according to the regulations canresult In an order to cease and desist and to be subject 10 penalties as provided for in Section 21'

See attached form foradditional information.

Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1, CERTIFICATE NUMBER: 16-R-0017 FORM APPROVED

ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036CUSTOMER NUMBER: 39

Connecticut College

~ANNUAL REPORT OF RESEARCH FACILITY 270 Mohegan Avenue(TYPE OR PRINT) New London, CT 06320

Telephone: (860) -Q9 233SO'

'1 3'{- ZIl(¥ ¥lr3. REPORTING FACILITY ( List all locations where animals were housed or used in actual research, testing, or experimentation, or held for these purposes. Attach additional sheets if necessary ) I

FACILITY LOCATIONS (Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY / Attach additional sheets if necessarY or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, accompanying pain or distress to the animals and for wh

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were the use of appropriate anesthetic, analgesic, or tranquiliz

OF ANIMALSBy The Animal teaching, testing, experiments, or conducted involVing drugs would have adversely affected the procedures, res

Welfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,research, or conducted distress to the animals an surgery, or tests. (An explanation of the procedures ( COLUMNSsurgery but not ye involVing no pain, for which appropriate producing pain or distress in these animals and the rease C+D+E)used for such distress, or use 0 anesthetic, analgesic, or such drugs were not used must be attached to this reportpurposes. pain-relieving tranquilizing drugs were

drugs. used.-_._~

4. Dogs 0---_.------

5. Cat$ 0---

6. Guinea Pigs 0---- _.-1------ .-

7. Har1sters 0---- .-

8. Rabbits 0---- -

9. Non-human Primates C>- -

10 Sheep 0.- -

11 Pigs 0 -

12 Other Farm Animals ()-----

-------

13 Other Animals 0-

--- ._---

N" 124c.)u-cJ.. ,4v.;~ ~ bo\l'~~'1 5 (J@c,e5ov J I

I ASSURANCE STATEMENTS I1) ProfeSSionally acceptable standards governing the care, treatment, and use of animals, including appropriate use of anestetic, analgeSIC, and tranquilizing drugs, prior to, dUring, and following actual reSe

teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has required that exceptions to the standards and regUlations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Committee (IACUC). A summary of all such exceptions Is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of animals affected.

ure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

ADQUARTERS RESEARCH FACILITY OFFICIAL

eror Legally Responsible Institutional Official)

DATE SIGNED

This report is required by law (7 USC 2143). Failure to report according to the regulations can See reverse side forresult in an order to cease and desist and to be subject to penalties as provided for in Section 2150 additional information

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. IANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0025 44

Interagency Report Control No0180-DOA-AN

FORM APPROVEDOMB NO. 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY(TYPE OR PRINT)

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA,

~~~ AUNIVERSITY OF CONNECTICUT HEALTH CENTER263 FARMINGTON AVENUEFARMINGTON. CT 06030

REPORTING FACILITY (List all locations where animals were housed or used in actual research. testing. teaching, or experimentation, or held for these purposes. Attach additionalsheets if necessary.)

FACILITY LOCATIONS(SIfes)

CENTER FOR LABORATORY ANIMAL CAREFARMINGTON. CT 06032

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use APHIS FORM 7023A)

A. B. Number of C. Number of D. Number of animals upon E, Number of animals upon which teaching, F.animals being animals upon which experiments. experiments. research, surgery or tests were

Animals Covered bred. which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO.By The Animal conditioned, or research. surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involving anesthetic,analgesic, or tranquilizing drugs wouidteaching, testing, tests were accompanying pain or have adversely affected the procedures, results, or (Cols. C +experiments, conducted distress to the animals interpretation of the teaching, research, D + E)research, or involving no and for which appropriate experiments, surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthetic, analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs. used. must be attached to this reporl)

4. Dogs

5. Cats 15 15

6. Guinea Pigs 3 3

7. Hamsters 27 27

8. Rabbits 74 74

9. Non-Human Primates 1 1

10. Sheep

11 Pigs

12. Other Farm Animals

13. Other Animals

ASSURANCE STATEMENTS

1) ProfeSSionally acceptable standards governing the care, treatment, and use of animals, Including appropriate use of anesthetic, analgeSIC, and tranquilizing drugs, prior to, dUring.and following actual research, teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has reqUired that exceptions to the standards and regulations be specified and explained by theprincipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of all the exceptions is attached to this annual report. Inaddition to identifying the IACUC-approved exceptions, this summary includes a brief explanation of the exceptions. as well as the species and number of animals affected.

4) The allending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

10/18/2007

APHIS FORM 7023(AUG 91)

(Replaces VS FORM 18·23 (Oct 88), which is obsolete PART1-HEAOQUARTERS

Soo atl8che<l (orm (0(

lIdllibOlllll infwmiltion.'l"hi8 repO<l i. raquir90 by law (7 USC 2143). I';>lll,lro to report according '0 IIle ,egulaliQF15 can

der . d be ~ect I II" rllYfdtld I in SllcIlan 21'r~ult in an or to C88!e and~I an to $UD o pens Ml$ as p or

UNITED STA,TES DEPARTMENT OF "GRICULTURE 1. CERTIFlCA,TE NUMBeR; 16·R..Q026 FOR~ APPROVEDANIMAL AND PLANT HEALTH INSPECliON SERVICE

custOMER NUMBeR: 46OMll NO. 0579-0035~ ....

Quinnipiac UniversityANNUAL REPORT OF RESEARCH FACILITY Mt. Carmel Avenue

( TYPE OR PRINT) P.O. Box 125Hamden, CT 06518

Telephone: (203) -582·8958

3. REPOlmNG FACII..JTY (U$I.III~1Ionll WIlere anillt$l$~~ 0( UHllln 8ClUei reatIlrch, /MUng. (; exporllTlOnllUoo. or held for tnese purposee. All8CI't allGltiOflal Sheets if~e<:~ry I I

Vivarium - Buckman Center FACILITY lOCATIONS (Slt8ll) - ~ At.8ched Li.ting

I REPORT OF ANIMAI.S USED 8v OR UNDER CONTROL. OF RES~RCH FACILITY I A,ttae:h additional II'lIOIS If nlleOCCatv or UGa APHIS J:0IIIl 7023A. I IA. B. NuITiler of animal C. Numbarol D. Number of anlmalli upon E. I'llmtJer of animalS upon iMliCII le~ing, OXperimon15. F.

btltng brecl, animals upon wt1jCl1 expsrtments, research. $l,II"gOl')' Qf 18$1& were conducted Involvingcoruljtionsd. or lNI'liehltachinll, le&Cllin9. _th. accompanYlIlg pain or distress to lila animals and for wII

TOTAL NUMBERAnlm8lS CClVlltlld held for use III rll&BBrch, SlXgery, or tests ware the use 01 appropriate anel;lhetiC. i'lnalg_ic, or lrBnQuiliz '

OFANIMA~S8y TheAnlm1l1 teaclling. les~ng. experiments. or conducted inllOlVln9 dtugs would noyo adVlN""..eIy affected lhe pracedlJfes, resWelfare Regulallol'lll expetimetl\$. tesls_ ~an\ling~in or or in!G<pretation o( tha teaching. reMarcll. expetionants.

(COLUMNSruearch, or conducted dislrB8s 10 !he animals an surget)', or lBSls. (Nt oxplanatign of \11" prgcedurB5""rgery but nal yE Involving no pain. lor Whlctl approprlala prodUCing pSin 0' di$ll'055 in these animals and !he reas< C+D+E)~9ed (or suCh distress. or 1,1$0 go aneslhetie. al'lillgllSic. or suro drugs were nOI used must be allacllBd to IIliS repol1PWPIlSO$. ~in-r"Helling tranquillzil1\l druljS wera

drugs. U5ed..- ...........,

4, Dogs

5. cats-a. Gl,li'*l Figs _. _..

7. HBm~rs 0 18 n 0 18

a. Rallblts 0 0 6 0 6- ......

9. Non-hl,lmlln PrImates

10. Sheep _.~~

11. Pigs

12. Oll'l&r Farm Anirrulis

Gerbils 0 18 0 0 18

13. Other AnilTlllls ._------

.. ..•.-

I ASSURANCe STATEMeNTS I1) PloIesslonally acceplllble standards goWltt1ln9 tI'le eare. If8almen~ and use Of anllTlSls, InclUding appropl'!4le Ulio of 1ll1l3tedc, analgesic. end lr'anqulllilll1\l drugs. p1ior 10, IlUl1ng, IItld fOllOWIng actual re9!

IBBctling. tes~ng. surgery. or BlCpetlmentallOl'l_e folloWed Dy thiS res.ardl faclilly.

2) each prjnclpallmH~!lllgalor has conaIdeI'e<l a~ti_ 10 oslntul proeedu~.

3) Thla lacllity is .dhenng to !he llWtllatd$ ....d re~ladontl utIdet"" Act, IIl1d It hes reqUired th*t _lDPtians to lhe atandards and r~gl.lialions be speCified and axplaine<l Dy the princlpellnvesugalo, llI'Id aplnsUiutional Animal Care snd U!le COmmin"" (IACUC). A &UJl1InIlrY <1f ..I .....h u4l6ptlQ....._had 10 ibis 8MueI~.In additIOn to IdenUrylng lIle IACUC-BPProve<l excepllons. l~i!l9lJ1Tmary inrbrief expla~~on of lila IWl8DtiOl'l$.lI$ well as the Illlscies snd nu"lber of animara alleclod.

4) The anendlng IHllerinati.n lor !hil research (aeilily has approprlata a~ltIority to tIIl&ur8 the ptOvi$ion of ~lIQUat8 veterinary eats and 10 Ov"lHB the lIlleqUacy o( orhat '$p8C1S of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACIUTY OFFICIAl. ve OffIcer Of legally Responsible Institutional 0fIk:11I1 )

INSTITUTIONA~

lete.)

OATI;SIGI"olEO

This report is required by law (7 USC 2143). Failure to report according to the regulations

can

See attached form foradditional information

C#3S-'Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0028 FORM APPROVED,4-ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036 [t--

CUSTOMER NUMBER: 35

U.S. Surgical Corporation

ANNUAL REPORT OF RESEARCH FACILITY Covidien

( TYPE OR PRINT) 150 Glover Avenue

Norwalk, CT 06856

Telephone: (203) -845-1000

3. REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, or experimentation, or held for these purposes. Attach additional sheets If necessary ) IFACILITY LOCATIONS ( Sites) - See Atached Listing

I REPORT OF ANIMALR lJRED BY OR lJNDER CONTROL OF REREARCH FACILITY I Attach additional ShMt!; if necessarY or use APHIS Form 7023A I IA. B. Number of C. Number of D. Number of animals E. Number of animals upon which teaching, F.

animals being animals upon upon which experiments, research, surgery or tests werebred, which teaching, experiments, teaching, conducted involving accompanying pain or distress TOTAL NUMBER

Animals Covered conditioned, or research. research, surgery, or to the animals and for which the use of appropriate OF ANIMALSBy The Animal held for use in experiments, or tests were conducted anesthetic, analgesic, or tranquilizing drugs wouldWelfare Regulations teaching, tests were involving have adversely affected the procedures, results, or

testing, conducted accompanying pain or interpretation of the teaching. research, experiments, ( COLUMNS

experiments, involving no distress to the animals surgery, or tests. (An explanation of the procedures C+D+E)

research, or pain, distress, or and for which procucing pain or distress in these animals and thesurgery but not ye use of pain- appropriate anesthetic, a reasonS such drugs were not used must be attached to

relieving drugs.

4. Dogs 389 3895. Cats

6. Guinea Pigs

7. Hamsters

8. Rabbits

9. Non-human Primate

10. Sheep

11. Pigs 1 427 427

12. Other Farm Animals

13. Other Animals

Total 1 816 816I ASSURANCE STATEMENTS I

1) Professionally acceptable standards governing the care, treatment, and use of animals, Including approprrate use of anestetlc, analgesIc, and tranqUIliZing drugs, prror to, durrng, and follOWingactual research, teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painfUl procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principalinvestigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of all such exceptions is attached to this annual report. In addition to identifying theIACUC-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

IN~ ICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL ( Type or Print DATE SIGNED

fZ-fJ-/,17

(AUG91 )

8-23 (OCT 88), which IS obsolete.

This report is required by law (7 USC 2143). Failure to report according to the regulations can See reverse side forresult in an order to cease and desist and to be subject to penalties as provided for in Section 2150 additional information

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. IANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0031 56

Interagency Report Control No0180-DOA-AN

FORM APPROVEDOMB NO. 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY(TYPE OR PRINT)

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA,

include Zip Code) ~

SEA RESEARCH FOUNDATION INC

55 COOGAN BOULEVARD

MYSTIC, CT 06355-1997

REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, teaching, or experimentation, or held for these purposes. Attach additionalsheets if necessary.)

FACILITY LOCATlONS(sltes)

SEA RESEARCH FOUNDATIONMYSTIC, CT 06355-1997

MYSTIC MARINE LIFE AQUARIUMMYSTIC, CT 06355-1997

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use APHIS FORM 7023A)

A. B. Number of C. Number of D. Number of animals upon E. Number of animals upon which teaching, F.animals being animals upon which experiments, experiments, research, surgery or tests were

Animals Covered bred, which teaching, teaching, research, conducted involving accompanyin9 pain or distress TOTAL NO.By The Animal conditioned, or research, surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involVing anesthetic,analgesic, or tranquilizing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, resulls, or (Cols. C +experiments, conducted distress to the animals interpretation of the teaching, research, D+ E)research, or involVing no and for which appropriate experiments, surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthetic. analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs. used. must be attached to this report)

4. Dogs

5. Cats

6. Guinea Pigs

7. Hamsters

8. Rabbits

9. Non-Human Primates

10. Sheep

11. Pigs

12. Other Farm Animals

13. Other Animals

California sea lion 4 4

Beluga whale 3 3

Northern fur seal 3 3

ASSURANCE STATEMENTS

1) ProfeSSionally acceptable standards governing the care, treatment, and use of animals, Including appropnate use of anesthetic, analgeSIC, and tranqUilizing drugs, pnor to, dunng,and following actual research, teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS facility IS adhenng to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by theprincipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of all the exceptions is attached to this annual report. Inaddition to Identifying the IACUC-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinanan for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

10/26/2007

APHIS FORM 7023(AUG 91)

(Replaces VS FORM 18·23 (Oct 88), which Is obsolete PART1-HEADQUARTERS

This report is required by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 2150

See reverse side foradditional information

Interagency Report Control No0180-DOA-AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. I FORM APPROVEDANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-R-0031 56

OMS NO. 0579-0036

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA,

CONTINUATION SHEET FOR ANNUAL REPORT include Zip Code)

OF RESEARCH FACILITY SEA RESEARCH FOUNDATION INC55 COOGAN BOULEVARD

(TYPE OR PRINT) MYSTIC, CT 06355-1997

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use this form.)

A. B. Number of C, Number of D. Number of animals upon E. Number of animals upon which teaching, F,animals being animals upon which experiments, experiments, research, surgery or tests were

Animals Covered bred, which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO.By The Animal conditioned, or research, surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involving anesthetic,analgesic, or tranquilizing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, results, or (Cols. C +experiments, conducted distress to the animals interpretation of the teaching, research, D + E)research, or involVing no and for which appropriate experiments, surgery, or tests. (An explanation ofsurgery but not pain, distress, or anesthetic, analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs. used. must be attached to this report)

Steller sea lion 4 4

Harbor seal 1 1

ASSURANCE STATEMENTS

1) ProfeSSionally acceptable standards governing the care, treatment, and use ot animals, Including appropriate use ot anesthetiC, analgeSIC, and tranquIlizing drugs, prior to, dUring,and follOWing actual research, teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS faCIlity IS adhering to the standards and re9ulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by theprincipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of aU the exceptions is attached to this annual report. Inaddition to identifying the IACUC-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

(Chief Executive Officer or Legally Responsible Institutional official)I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

10/26/2007

APHIS FORM 7023A

(AUG 91)(Replaces VS FORM 18·23 (Oct 88), which is obsolete PART 1 - HEADQUARTERS

This report IS required by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 21 1

See attached form foradditional information.

Interagency Report Control No.:

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0040 FORM APPROVED 14.ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036 'J....

CUSTOMER NUMBER: 10301

Northwestern C T Community CollegeANNUAL REPORT OF RESEARCH FACILITY Park Place East

( TYPE OR PRINT) Winsted, CT 06098

Telephone: (860) -738-6483

3. REPORTING FACILITY (list all locations where animals were housed or used in actual research, testing, or experimentation, or held for these purposes. Attach additional sheets if necessary ) IFACILITY LOCATIONS ( Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY I Attach additional sheets if necessarY or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, accompanying pain or distress to the animals and for vvtl

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were the use of appropriate anesthetic, analgesic, or tranquilizBy The Animal teaching, testing, experiments, or conducted involving drugs would have adversely affected the procedures, res

OF ANIMALS

Welfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,research, or conducted distress to the animals an surgery, or tests. ( An explanation of the procedures ( COLUMNSsurgery but not y' involving no pain, for which appropriate producing pain or distress in these animals and the reas( C+D+E)used for such distress, or use o· anesthetic, analgesic, or such drugs were not used must be attached to this reponpurposes. pain-relieving tranquilizing drugs were

drugs. used.- -----------

4. Dogs - '-----"-----

5. Cats to CD-~- --------

6. Guinea Pigs d. ~--

7. Hamsters , I-------------

8. Rabbits \ i--------------- ---9. Non-human Primates - -------------- f-----o Sheep '-- --

--~----- --11 Pigs -- ~-~

----------1---

12. Other Farm Animals -- ~

~-,~----------

------------

13. Other Animals -------..-----,-.--- - - --~-

-- f----------

----- -- -----

-- -----~-------

ASSURANCE STATEMENTS I1) Professionally acceptable standards governing the care, treatment, and use of animals, including appropriate use of anestetlc, analgeSIC, and tranqUilizing drugs, prior to, dUring, and following actual res,

teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) ThiS facility is adhering to the standards and regulalions under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstHulional Animal Care and Use Committee (IACUC). A summary of att such exceptions Is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

N

DATE SIGNED

II. 1-0/(71

This report is reqUired by law (7 USC 2143). Failure to report according to the regulations canresult in an order to cease and desist and to be subject to penalties as provided for in Section 21'

See attached form foradditional informalion.

Interagency Report Control No..

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0042 FORM APPROVED

ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036CUSTOMER NUMBER: 15694

American Integrated Biologics Inc 4-ANNUAL REPORT OF RESEARCH FACILITY PO Box 252

( TYPE OR PRINT) East Woodstock, CT 06244Dc-! ,.

1 ;) 2DD!Telephone: (860) -963-2612

3. REPORTING FACILITY ( List all locations where animals were housed or used in actual research. testing, or experimentation. or held for these purposes. Attach additional sheets if necessary ) IFACILITY LOCATIONS (Sites) - See Atached Listing

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY I Attach additional sheets if necessarY or use APHIS Form 7023A I IA. lB. Number of animal C. Number of I D. Number of animals upon IE. Number of animals upon which teaching. experiments. IF.

I

being bree. animals upon whicil expt:!riI11erlb, research, surgery or tests '-\tare :::onducted involvingconditioned, or which teaching,

Iteaching, research,

Iaccompanying pain or distress to the animals and for wh I

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were the use of appropriate anesthetic. analgesic. or tranquilizOF ANIMALS

~y TI1~ ~n~~::,' teaching, testing, experiments, or conducted involv''1g drugs WOL!ld have adversely affected the procedures, resWelfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,

research, or conducted distress to the animals an surgery. or tests. (An explanation of the procedures ( COLUMNS

surgery but not ye involving no pain. for which appropriate producing pain or distress in these animals and the reasc C+D+E)used for such distress, or use o· anesthetic, analgesic, or such drugs were not used must be attached to this reponpurposes. pain-relieving tranquiliZing drugs were

drugs. used.- ~~~---~-

4 Dogs

- I--- -

5 Cats---------+ · -

6. Guinea Pigs

--------_._-- ----

7. Hamsters

-~------

8. Rabbits-~

9. Non-human Primates

-------

10 Sheep

--~-'---------f---. · -

11 Pigs ,3 ~J-~ · -

12. Other Farm Animals -.!L I 5"-~--------- _. ~-----. -

(;oA-15~----_. -

13~ Other Animals II- I ---J----- ~~-~-I---- ~----------,----.----

-~ .-. -'---r- +- t--~--~---'~-r--

._----

I ASSURANCE STATEMENTS I1) Professionally acceptable standards governing the care, treatment. and use of animals. including appropriate use of anestetic, analgesic, and tranquilizing drugs, prior to. dUring, and following actual reSE

teaching, testing, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Committee (IACUC). A summary of all such exceptions Is attached to this annual report. In addition to identifying the IACUC-approved exceptions, this summary in<brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

APHIS

(A

Prinf) DATE SIGNED

Interagency Report Control No..This report Is required by law (7 USC 2143). Failure to report acc:crdlng to the regulaUons can See attached form forresult In an order to cease and de5lsl and 10 be subject to penal '5 provided for in Section 21' lddiUcr-' nformaUon.----------....-----"""" -----+...,.-------

UNITED STATES DEPARTMENT OF 1\uRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE1. CERTIFICATE NUMBER: 16-R-0044

CUSTOMER NUMBER: 20922

FORM APPROVEDOMB NO. 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY( TYPE OR PRINT )

Bayer Pharmaceutical CorporationManager Veterinary Resources400 Morgan LnVVestHaven,CT 06516

000..--..r6V ,;0 ~. Telephone: (203) -812-5046d- ,/,00t.~/

3. REPORTING FACILITY (Losl alilocabons where a",,,.."-. housed or used In actual research. tesUng. or expenmenlaUon. or held for these purposes. Attach ae dilional sheets If necessary )

FACIUTY LOCATIONS (Sites) • See Atached UsUng

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACIUTY ( AttlIch additional sheets If nec:euarv or us. APHIS Form 7023A I

A.

Anima" CoveredBy The AnIINlI

WeIfa ... RegulaUona

B. NurrOer of8IIIrreis beingbred, condiUoned.or held tor use Inleaching. lesting,e.penmenlS,research. orIUfV8l'Y but noI Ytuaed tor suchpurposes.

C. NImlerof8III"..ls uponwhk:h leaching.~,

apenments. orteats werealIlducIedimIoIving no paln.cIalreaa, or use 01

peIno<'ellevtngdrugt.

D. Nuntler of anl"..l. uponwhich expenments.leeching. research.1Ufll8IY. or lesta __conducted Involving~ying paln orIIatresa to the anl"..ls antor which apptOflrtateeneathetlc, analgesic, ortranquilizing drugs __

uaed,

E. Number of anl"..ls upon whIch leachi g, expenmenls,research, surgery or lests were condu ted involvingaa:ompanying pain or distress 10 the ~nimals and for whthe use of appropriate anestheUc, ana gesic, or tranquilizdrugs would have adveraely affected t e procedures,results. or InterpretaUon of the leachin ,research,expenments. surgery. or tests. (An e planation of theprocedures prodUcing pain or distress In these animais athe reasons such drugs were not used must be attachedthis report ).

F.

TOTAL NUMBEFOF ANIMALS

(COLUMNSC+O+E)

4, Dogs

5. Cats

8. Guinea Pigs

7. Hamsters

;).5

8. Rabbits

-,-------+-------f.-------l----.-I------l-------------f-----t-----,---,.----'f l-f

g. Non·human Primates

10. Sheep

11. Pigs

12. Other Fann Animals

13. Other Animals

---------I--------I--------+-----------!--------------I------+-------

ASSURANCE STATEMENTS I1) Proteaaionally IICQIptable llanc*Ila gOVWTIlI'Ig the c:arw,~ .00 use of lII1lmlIla, including lIPIlf'OPI'Nde use of aneatetIc, _Igesic, IIld tnlnquilizing drugs, prior 10, during, and following actuai reS{

tNchlng, leating. surgery. or~__ tollowecl by lhia~ fllcitity.

2) Each principal investigator has COI1SIdered an.mativM to painfUl procecUea.

3) Thll tadlity Is adhering to the ltand8rda .00~ lrIder the Ad, IIld It haa rwquired tNt exceptions to the atand8nllI.oo regulations be apec:itied and expla'ned by the principal investigator and coInatilutional Animal Care IIld Use CommlttM (IACUC). A summary of all such axcapUona Is attached 10 thla annual report. In addition to identifying the IACU -approved exceptions, Ihis summary Incbrief explanation of the excapoona... MIl .. the apaaea .00 runber of lInim8la atIedecI.

4) The attending velerinanan for this.-ch faality has 8IlPfOIlliale 8UIhOrity 10 anauno the provillon of adequate veterinary care and'" ovaraee the adequacy of 0 her aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive omcer or Legally Responsible Institutional Otncial )

3IGNATU'\::~~C:0v'0:NS(T:.ONl'J"LX

f\?'),~ .'-~ FIl~M i~Olaces oSOlete.)

\')"'~~ ~

DAf E ~,il. "if.,

!

Interagency Report Control No.:See attached form foradditional information

This report is required by law (7 USC 2143). Failure to report according to the regulations cand d . t d t b b' t t If 'd d f . S cto 21'result in an order to cease an eSls an 0 e su Jec o pena les as previ e or In e In

UNITED STATES DEPARTMENT OF AGRICULTURE 1. CERTIFICATE NUMBER: 16-R-0048 FORM APPROVED

ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO. 0579-0036CUSTOMER NUMBER: 40515

Western Connecticut State University t&ANNUAL REPORT OF RESEARCH FACILITY 181 White St

J;fl~re$'~ PRINT) Danbury, CT 06810W ;'.:":J.,;< ~'",,4;;'

Telephone: (203) -837-8281

3.REP<W~~~~M~~~~FJt~IS were housed or used in actual research, testing. or experimentation. or held for these purposes. Attach additional sheets if necessary) I

FACILITY LOCATIONS ( Sites) - See Atached ListingBiology DepartmentScience Building

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY I Attach additional sheets if necessarY or use APHIS Form 7023A I IA. B. Number of animal C. Number of D. Number of animals upon E. Number of animals upon which teaching, experiments, F.

being bred, animals upon which experiments, research, surgery or tests were conducted involvingconditioned, or which teaching, teaching, research, - accompanying pain or distress to the animals and for wh

TOTAL NUMBERAnimals Covered held for use in research, surgery, or tests were - the use of appropriate anesthetic, analgesic, or tranquilizOF ANIMALSBy The Animal leaching, testing, experiments. or conducted involving drugs would have adversely affected the procedures, res

Welfare Regulations experiments, tests were accompanying pain or or interpretation of the teaching, research, experiments,research, or conducted distress to the animals an surgery, or tests. (An explanation of the procedures (COLUMNSsurgery bul nol ye involving no pain, for which appropriate producing pain or distress in these animals and the rease C+D+E)used for such distress, or use a anesthetic, analgesic, or such drugs were not used must be attached to this reportpurposes. pain·relieving tranquilizing drugs were

drugs. used.

4. Dogs

..-5. Cats

---' _.--6. Guinea Pigs

~,.-

7. Hamsters

--8. Rabbits

_..-

9. Non-human Primates

10. Sheep

11. Pigs

.12. Other Farm Animals

----

13. Other Animals

Gerbils 6 6

I ASSURANCE STATEMENTS I1) Professlom4ly acceptable standards governIng the care, treatment, and use of animals, Indudmg appropnate use of anestellc, analgeSIC, and tranquillzmg drugs, prior to, dunng, and follOWIng actual rese

teaching, tetting, surgery, or experimentation were followed by this research facility.

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regUlations under the Act, and it has required that exceptions to the standards and regulations be specified and explained by the principal investigator and apInstitutional Animal Care and Use Corrrnittee (IACUC). A summary of all such exceptions Is attached to this annual report, In addition to identifying the IACUC-approved exceptions, this summary incbrief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of other aspects of animal care and use.

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

( Chief Executive Officer or Legally Responsible Institutional Official)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL DATE SIGNED

APHIS FORM 7023

(AUG91 )(Replaces VS FORM 18-23 (OCT 88), whIch IS obsolete,)

ThiS report is required by law (7 USC 2143). Failure to report according to the regulations can See reverse side forresult in an order to cease and desist and to be subject to penalties as provided for in Section 2150 additional information

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. CUSTOMER NO. IANIMAL AND PLANT HEALTH INSPECTION SERVICE 16-V-0002 454

Interagency Report Control No0180-DOA-AN

FORM APPROVEDOMS NO. 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY(TYPE OR PRINT)

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered with USDA,

include Zip Code) , ,nVA MEDICAL CENTER (689) t<.:J..r-'950 CAMPBELL AVENUEWEST HAVEN, CT 06516

REPORTING FACILITY (List all locations where animals were housed or used in actual research, testing, teaching, or experimentation, or held for these purposes. Attach additionalsheets if necessary.)

FACILITY LOCATIONS(sltes)

VA MEDICAL CENTER (689)WEST HAVEN, CT 06516

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach additional sheets if necessary or use APHIS FORM 7023A)

A. B. Numberof C. Number of D. Number of animals upon E. Nuntler of animals upon which teaching, F.animals being animals upon which experiments, experiments. research, surgery or tests were

Animals Covered bred, which teaching, teaching, research, conducted involving accompanying pain or distress TOTAL NO.Sy The Animal conditioned, or research, surgery, or tests were to the animals and for which the use of appropriate OF ANIMALS

Welfare Regulations held for use in experiments, or conducted involving anesthetic,analgesic, or tranquilizing drugs wouldteaching, testing, tests were accompanying pain or have adversely affected the procedures, results, or (Cols. C +experiments, conducted distress to the animals interpretation of the teaching, research, D+ E)research, or involving no and for which appropriate experiments, surgery, or tests, (An explanation ofsurgery but not pain, distress, or anesthetic, analgesic, or the procedures producing pain or distress in theseyet used for such use of pain- tranquilizing drugs were animals and the reasons such drugs were not usedpurposes. relieving drugs, used. must be attached to this report)

4. Dogs

5. Cats

6. Guinea Pigs

7. Hamsters

8. Rabbits

9. Non-Human Primates 8 6 45 51

10. Sheep

11. Pigs

12. Other Farm Animals

13. Other Animals

ASSURANCE STATEMENTS

1) Professionally acceptable standards governing the care, treatment, and use of animals, Including appropriate use of anesthetiC, analgeSIC, and tranquilizing drugs, prior to, dUring,and following actual research, teaching, testing, surgery, or experimentation were followed by this research facility,

2) Each principal investigator has considered alternatives to painful procedures.

3) This facility is adhering to the standards and regulations under the Act, and it has reqUired that exceptions to the standards and regulations be specified and explained by theprincipal investigator and approved by the Institutional Animal Care and Use Committee (IACUC). A summary of all the exceptions is attached to this annual report. Inaddition to identifying the IACUC-approved exceptions, this summary includes a brief explanation of the exceptions, as well as the species and number of animals affected.

4) The attending veterinarian for this research facility has appropriate authority to ensure the provision of adequate veterinary care and to oversee the adequacy of otheraspects of animal care and use

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL(Chief Executive Officer or Legally Responsible Institutional official)

I certify that the above is true, correct, and complete (7 U.S.C. Section 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME & TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Print) DATE SIGNED

11/16/2007

APHIS FORM 7023(AUG 91)

(Reptaces VS FORM 18·23 (Oct 88), which is obsolete PART1-HEADQUARTERS