www.CUREepilepsy.org

Citizens United for Research in Epilepsy

Our Mission

is to CURE epilepsy, transforming and saving

millions of lives. We identify and fund cutting-edge

research, challenging scientists worldwide to

collaborate and innovate in pursuit of this goal.

Our commitment is unrelenting.

CURE

2016 CURE EPILEPSY AWARDDaniel Barth, PhD

University of Colorado – Boulder

“The Role of Neuro-inflammation in a Rat Model of

Comorbid Epilepsy and Autism”

Avtar Roopra, PhD

University of Wisconsin – Madison

“Epigenetic Regulation of Tonic Inhibition in Epilepsy”

Annapurna Poduri, MD, MPH

Children’s Hospital Boston

“Genetics of Sudden Unexpected Death in Pediatrics and Hippocampal

Pathology—A Novel Entity Linking SIDS and SUDC to Epilepsy”

Kristina Simeone, PhD

Creighton University

“Orexin triggers autonomic destabilization

in SUDEP”

2016 CURE EPILEPSY AWARD

Rup Sainju, MBBS

University of Iowa – Iowa City

“Abnormal ventilatory response to CO2 in epilepsy patients:

a potential biomarker for seizure induced respiratory depression

& modification by SSRI”

2016 CURE EPILEPSY AWARD

Mingshan Xue, PhD

Baylor College of Medicine

“Novel Models of Epileptic Encephalopathies”

In Honor of Felix Henry

Stephen Traynelis, PhD

Emory University

“Functional and Clinical Evaluation of NMDA

Receptor Mutations in Epileptic Encephalopathy”

Antonello Mallamaci, PhD

Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

“Scalable transcriptional-translational therapy of

epileptogenic gene haploinsufficiencies”

2016 INNOVATOR AWARDMarta Biagioli, PhD

University of Trento, Trieste, Italy

“SINEUPs Technology: a New Route to Treat

Haploinsufficiency-Induced Epilepsy”

Akiko Nishiyama, MD, PhD

University of Connecticut

“Reprogramming NG2 glial cells into inhibitory neurons

in an epilepsy model”

In Honor of Vivian L. Cotton

2016 TAKING FLIGHT AWARD

Rene Barro Soria, PhD

University of Miami

“Molecular mechanisms of epilepsy-causing mutations in the

IKM channel: anti-epileptic effect of polyunsaturated fatty acids

(PUFAs) variants”

Stuart Cain, PhD

University of British Columbia

“Examining the link between seizures,

spreading depression and SUDEP”

Laura Ewell, PhD

University of California – San Diego

“Pediatric epilepsies: microRNAs determine

network excitability during development”

Kenneth Myers, MD, PhD

University of Melbourne

“Genetic Prediction of Drug Response in

Childhood Absence Epilepsy”

2016 TAKING FLIGHT AWARD

HOPE RESEARCH CURE

3 MILLION AMERICANS65 MILLION WORLDWIDE

CURE has funded 200+ research projectsin 15 countries around the world.

AUSTRALIAAUSTRIACANADAFINLANDFRANCE

GERMANYIRELAND

ISRAELITALY

NETHERLANDSSOUTH KOREA

SWEDENUK

UKRAINEUSA

CURE has hosted 31 epilepsy research seminars in 19 states and 5 countries, attended by 2000+ scientists.

35 SEMINARS

19 STATES

5 COUNTRIES

2000+ ATTENDEES

EPILEPSY GENETICS INITIATIVE

EGI is a $1M initiative created to bridge

the gap between people with epilepsy,

clinicians, and researchers and advance

precision medicine in epilepsy.

SUDEP INITIATIVE

CURE has invested $3.75M to projects

that address the goal of understanding

and eliminating SUDEP.

PTE / TBI INITIATIVE

Funded by a $10 million grant from the

U.S. Department of Defense, this program

supports a team approach to researching

the prevention and treatment of

post-traumatic epilepsy.

INFANTILE SPASMS INITIATIVE

CURE has awarded over $4.1 million to

accelerate the understanding of infantile

spasms and advance a new, disease-

modifying therapy into the clinic.

Signature Programs

Research Programs for a CURE* Efficiency of CURE’s Expenditures*

*2015 portfolio