NEVER LOSE SIGHT OF WHAT’S IMPORTANT

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PRESENTING AFAMILY OFQUALITY NATURALNUTRACEUTICALS

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QUALITY CONTROL

GMPs are a system of procedures and documentation, written and analytical, toensure that the product produced has the identity, strength, composition, quality,and purity that it claims. GMPs apply to all activities associated with manufacturing,packaging, holding, and distribution. GMPs cover areas such as personnel, plantand grounds, sanitation of building and facilities, equipment and utensils, qualityassurance/control and laboratory operations, production and process controls,warehousing, distribution and post-distribution processes, and records retention.

GMP Certified | Formulated by PhD and DVM Collaboration | Pharmaceutical Grade MaterialsPatented Formulas | Peer Reviewed, Published Clinical Studies Trusted by Aquarium and Zoo Veterinarians Around the World

How do you know which vitamins andsupplements to trust for your animals?

Animal Necessity supplements are certifiedunder FDA Good Manufacturing Practice (GMP)regulations. You can be confident that eachingredient proudly listed on our labels is sourcedfrom the highest quality, pharmaceutical gradematerial available and handled with the strictestmanufacturing controls in the world.

These statements have not been evaluated by the Food and Drug Administration. Products may appear differently than presented. These products are not intended to treat, diagnose, cure or prevent any disease.

CATALOG LIST

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2 - 7 Company Info

8 - 15 List of Proprietary Blends

- Imuno-2865 TM

- Serenin Vet TM

- Ocu-GLO Rx TM

- Joint Guard TM

- SHaNa Vet TM (Capsules & Cream)

16 - 17 Other Blends

- Artichoke and Milk Thistle

- Digestin Vet

- Alpha Lipoic Acid

- Neuroplex

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Animal Necessity focuses on delivering highquality nutritional products and services toveterinary health professionals around theworld. Our holistic approach to healthmaintenance has been developed over the past35 years by Orthomolecular Nutritionist, Dr.Norma Pestano. Through her extensiveresearch, Dr. Pestano seeks to maintain healthand prevent diseases by optimizing nutritionalintake, complemented with vitamin andsupplement protocols. Dr. Pestano haspartnered with leading DVM’s and BoardCertified Veterinary Specialists to apply manyof these human based protocols towardsveterinarian specific use. In 2012 over two-dozen products are now available with dosingfor large and small animal nutrition. AnimalNecessity remains committed to gathering anddelivering the latest and most relevant sciencerelated to Complementary and AlternativeMedicine that will support Veterinarian HealthProfessionals.

The Animal Necessity Scientific Advisory Team(ANSAT) is a collaborative group ofmultidisciplinary experts, led by Dr. JohannaMejia-Fava, who will work alongside AnimalNecessity to establish a unique knowledgesharing platform for veterinary communitiesacross the world. ANSAT includes scientists,board certified veterinary specialists, DVMs,curators and trainers who share an interest incomplementary veterinary medicine and areinterested in promoting its advancement.

Commitment to Science

COMPANY OVERVIEW

Who We Are

Animal Necessity's mission is to provide a comprehensive approach to animal wellness,by incorporating the latest research with pharmaceutical grade nutraceuticals to helpanimals live healthier lives. We seek to drive advancement in the field through natural,holistic and scientific methods.

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Trusted by zoo andaquarium

veterinariansaround the world

Our productscome fromthe purestnaturalmaterials

Proven safeand effectivefor humanconsumption

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OUR CIRCLE OF CARE

Scientificallyformulated for

use incompanionanimal care

Our circle of care began with establishing a standardof quality for natural human products, a standardthat we have brought to zoo, aquarium andcompanion animal medicine.

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Animal Necessity is committed to providing high quality customer service and a

variety of easy ordering options.

OrderS can be Placed uSing any Of the fOllOwing methOdS:

Online: www.animalnecessity.comPhone: 1-800-721-1310

fax: 212-202-7818email: customer.service@animal-necessity.com

hOurS Of OPeratiOn: monday – friday, 10 a.m. – 6 p.m. eSt

Orders usually ship within 24 hours.

OrDeringinFOrmATiOn

PROPRIETARY BLENDSLiST OF PrODuCTS

imuno-2865 tm

- immune Adjunctive Support

Serenin Vet tm

- natural Anti-anxiety & Calming Aid

Ocu-glO rx tm

- Optimal canine vision support

Joint guard tm

- Hip and joint support

Shana Vet tm (caPSuleS & cream)- Skin and Coat Support

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PROPRIETARY BLENDS

imuno-2865 tm

- immune Adjunctive Support

Serenin Vet tm

- natural Anti-anxiety & Calming Aid

Ocu-glO rx tm

- Optimal canine vision support

Joint guard tm

- Hip and joint support

Shana Vet tm (caPSuleS & cream)- Skin and Coat Support

Under 20 lbs ½ capsule

20-50 lbs 1 capsule

50-100 lbs 2 capsules

100-150 lbs 3 capsules

150-200 lbs 4 capsules

Imuno-2865 (NatramuneTM) is a naturallyobtained hemicellulose (high molecularweight polysaccharide complex) and fattyacid mixture extracted from natural sources(Gramineae, Poaceae, Dioscoreaceae familyof plants and/or several species ofmushrooms).

1. The Affects of NatramuneTM (PDS-2865®), A NewImmunostimulator Supplement on Different Cetacean Species;Tursiops truncatus, Lagenorhynchus obliquidens, and Orcinusorca. Proceedings of the IAAAM, 38, 44-45.

2. Rodriguez M, Mejia J, Blanchard M, Stott J, Pestano N, PerezP. (2008). NatramuneTM (PDS-2865®), An ImmunostimulatorSupplement in Cetaceans. Proceedings of the IAAAM, 39, 26

3. Chavoustie S, Perez P, Fletcher M, Maher K, Mitrani A, ThomasR. Pilot Study: Effect of PDS-2865 on Natural Killer CellCytotoxicity. Journal of the American Nutraceutical Association,Vol. 6, No. 2: pp. 39-42, 2003.

4. Weeks BS, et al. The hemicellulose preparation, NatramuneTM(PDS-2865)®. Increases macrophage phagocytosis and nitric oxideproduction and increases circulating human lymphocytes levels.Med Sci Monit. 2009; 15(2): BR43-46.

5. Weeks BS, et al. Natramune and PureWay-C reduce xenobiotic-induced human T-cell α5β1 integrin-mediated adhesion tofibronectin. Med Sci Monit. 2008; 14(12): BR279-285.

IMUNO-2865T M

Helps maintain healthy gastrointestinal function

Enhances immune system response and the body’s first line and second line defense and other important funtional components of the immune system

Enhances immune system activity

Product Description

Published Studies

Ingredients

Baseline Dosages

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PDS-2865® ProprietaryBlendPolysaccharide Complex ExtractRice FlourRice BranMicrocrystalline celluloseGrapeseed Extract

1000 mg

NUTRITION AMOUNT PERSERVING

Serving Size: 2 capsules

The above doses are for preventative health. For specific diseases, please contact Animal Necessity for afree consultation.

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SERENIN VETT M

Natural calming and anti-anxiety support

Anti-anxiety support for aggression and other anxiety related conditions or behavior problems.

Serenin VetTM is a unique combination of plantingredients, amino acids, fatty lipids, vitamins andminerals. Some of these ingredients have demonstratedthe ability to raise serotonin levels in the brain, whichmay lead to relief from depression, anxiety, andaggressive or nervous behavior.

Product Description

List of Ingredients

Vitamin B-6 (as pyridoxine HCl)

Folate (as folic acid)

Vitamin B-12 (as cyanocobalamin)

Magnesium (as magnesium oxide)

Selenium (as selenium amino acid chelate)

5-HTP (L-5-hydroxy-tryptophan

(Glyffonia simplicifolia) (seed)

DL- Phenylananine

Eleuthero powder (Eleutherococcus

senticosus)(rhizome)

Inositol

L-Tyrosine

St. John's Wort extract (Hypericum perforatum)(flower heads)(std. for 0.3%Hypericin (1.8 mg))

Passion flower extract (Passiflora incarnata) (aerial parts)(std. for >3.5%flavonoids as Isovetexin (1.75 mg))

NUTRITION AMOUNT PERSERVING

Serving Size: 2 capsules

25 mg

400 mcg

200 mcg100 mg

70 mcg

25 mg

40 mg

70 mg

100mg

10mg

600mg

50 mg

5-25 lbs ½ capsule, every other day

25-50 lbs 1 capsule, ever other day

500-100 lbs 1 capsule, daily

100-200 lbs 2 capsules, daily

Baseline Dosages

Dose may increase depending on severity of aggressionand anxiety, please contact Animal Necessity for dosing.Do not use Serenin if animal is on a monoamine oxidaseinhibitor (MAOI) or an antidepressant.

PDS-2865® Proprietary Blend(Polysaccharide complex extract, riceflour, rice bran, microcrystalline cellulose, cyclodextrin)

100 mg

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Ocu-GLO Rx ™ is a blend of 12 different antioxidants thatcomplement traditional therapy, and are formulated to protectvital cells in the eye at the DNA and protein levels from oxidativedamage occurring with ocular conditions including PRA, SenileRetinal Degeneration, Early Diabetic and other types ofSecondary Cataracts, pre and post-operative Cataract Surgery,Uveitis, Glaucoma, Optic Neuritis and Dry Eye.Formulated by Dr. Carmen Colitz, Dr. Terri McCalla and Debby Smith of Animal Health Quest.

Product Description

List of Ingredients

Ocu-GLO RxTM

GLO RxTM Proprietary Blend (GrapeSeed Extract 95%, Lutein 20%,Omega-3 55%)Vitamin C (as Ascorbic Acid)Vitamin E (as d-Alpha Tocopheryl)Vitamin B-1 (as Thiamine HCI)Vitamin B-3 (as Niacin)Vitamin B-6 (as Pyridoxine HCI)Folate (as Folic Acid)Vitamin B-12 (as Cyanocobalamin)BiotinPantothenic Acid (as d-Calcium Pantothenate)Zinc (as Zinc Oxide)Alpha Lipoic AcidCoenzyme Q10 (Ubiquinone)Lycopene from Tomato ExtractGreen Tea Extract 40% ECGCOther Ingredients: Gelatin, Glycerin,Beeswax, Lecithin, Soybean Oil andLiver Extract

NUTRITIONAMOUNT PERSMALL DOGGELCAP

AMOUNTPERMEDIUM/LARGEDOGGELCAP

175 mg

50 mg25 IU0.1 mg1.2 mg0.1 mg20 mcg2.5 mcg10 mcg1 mg

3 mg13 mg13 mg1 mg20 mg

351 mg

100 mg50 IU0.2 mg2.4 mg0.2 mg40 mcg5 mcg20 mcg2 mg

5 mg25 mg25 mg2 mg40 mg 10 lbs and under 1 gelcap for Small Dogs

10-30 lbs 1 gelcap for M/L Dogs

30-60 lbs 2 gelcaps for M/L Dogs

60-100 lbs + 3 gelcaps for M/L Dogs

Dosages

Specifically formulated to support canine eyes in health and disease

Includes Grapeseed Extract, Lutein, and Omega-3 Fatty Acids

Formulated by board certified veterinary ophthalmologists

Serving Size: 1 Gelcap

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JOINT GUARDTM

5-25 lbs 1/2 tablet

25-50 lbs 1 tablet

50-100 lbs 2 tablets

100-200 lbs 3 tablets

Baseline Dosages

List of Ingredients

Vitamin C (as ascorbic acid)Manganese (as manganesegluconate)Boswellia serrata extract (resin)Bromelain (from pineapple)Chicken collagen type IIChrondroitin Sulfate (bovine)Glucosamine HCL***Glucosamine sulfate (a D-glucosamine sulfate 2KCI)OptiMSM®MethylsulfonylmethaneTurmeric Extract (Curcumalonga) (rhizome)White Willow Bark Extract(Salix alba)

25 mg2 mg

75 mg50 mg50 mg750 mg200 mg550 mg

500 mg

200 mg

50 mg

NUTRITIONAMOUNT PER

SERVING

Supports maintenance of healthy joint cartilageAnti-inflammatory, anti-oxidant and pain relievingingredients

Product DescriptionJoint Guard™ is a unique blend of herbs and supplements thathelp improve and maintain joint comfort and range of motion.The formula includes both anti-inflammatory and anti-oxidantingredients that may offer relief from joint pain andosteoarthritis. Joint Guard also includes ingredients that helpnourish and replenish collagen, which is necessary for themaintenance of healthy joint cartilage.

* If your animal has any known allergies to pollen, grass, orplants please contact Animal Necessity for further information.** Note: Stop Joint Guard 2 weeks before surgery or dentalcleanings.*** Do not give to animals with shellfish allergies.

NUTRITION AMOUNT PERSERVING

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SHaNa VetTM is a blend of natural phytowax and botanical extracts with amino acids andvitamins consistently found in healthy skin,fur and keratin. Oral supplementation andtopical administration of SHaNa Vet hasbeen shown to relieve scaling, redness,itching, fissures, vesicles, and as effectivesupport for fungal disease fee skin.

Product Description

List of Ingredients

TopicalPlus® 500 mgProprietary Blend3% blend (Docosanol and Triacontanol)Vitamin A 2000 IUVitamin D 100 IU

SHaNa VetTM (CAPSULES)

Baseline Dosages

Under 50 lbs ½ capsule

50-100 lbs 2 capsules

100-200 lbs 4 capsules

Exhibits antiviral activity against several lipid enveloped viruses including Herpes Simplex

Helps enhance antiviral, anti-inflammatory and anti-fungal activity

Decreases viral replication, shortens healing time and duration of symptoms

Helps to protect the superficial layer of the epidermis, fur, and nails to aid in prevention of viral and fungal diseases.

The most important ingredients in SHaNa VetTM includesDocosanol and Tricontanol, which have been shown tohave anti-viral and anti-inflammatory activities. Clinicalstudies have shown that Docosanol inhibits infusionbetween envelope viruses, such as herpes simplex, andthe host cells, thus blocking entry and replication.Triacontanol (TRIA) has been known to exhibit anti-inflammatory action in animals and this anti-inflammatory effect of TRIA might be mediated throughinhibition of lipid peroxidation. Since LOX inhibitorshave been extensively used as their therapeutic agents,TRIA, being a natural compound has been suggested tobe an effective anti-inflammatory drug.

Shana contains plants, phytowaxes, and fatty alcohols that have anti-fungalproperties such as squalene, calendula, and triacontanol. Squalene is anatural lipid that is a precursor of cholesterol biosynthesis belonging to theterpenoid family and a precursor of cholesterol biosynthesis. Squalene issynthesized in humans, sharks, and a variety of organisms. Highintracellular fungal squalene concentrations are believed to interfere withfungal membrane function and cell wall synthesis.1 Calendula is flowerplant that contains esquiterpenes glycosides, saponins, xanthophylls, trioltriterpenes, and flavanoids. This plant has been studied in vitro anddemonstrated a wide spectrum against pathogenic fungi.2

SHaNa VetTM (CREAM)

SHANA cream 8/11/09 9/2/09

After (9/2/09)

SHANA cream 8/11/09 9/2/09

Before (8/11/09)

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1, 2 Please visit www.animalnecessity.com for references

ARTICHOKE & MILK THISTLE

List of Ingredients

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Artichoke flower extract (standardized forminimum 2.5% caffeyiquinic acids) (6.25 mg)

Milk thistle extract (Silybum marianus) (seeds,ground) Standardized for 80% silymarin (140 mg)

500 mg

200 mg

NUTRITION AMOUNT PERSERVING

DIGESTIN VET

Artichoke & Milk Thistle is a high potency herbal formula that is formulated for optimal liver health.Artichoke is a flower extract that helps improve digestion and aids in liver, gallbladder, and diuretickidney function. Milk Thistle contains 80% of silymarin, an important compound that nourishes theliver and helps protect it from cellular damage by providing antioxidant properties.

Product Description

Digestin Vet is an advanced formula that incorporates herbal ingredients,high potency digestive enzymes, and essential nutrients that help supportdigestion. This supplement contains lactobacillus acidophilus, providing1 billion active organisms at time of manufacture, which helps maintainand restore normal bacterial balance in the gastrointestinal tract. Patientswith inflammatory bowl disease, pancreatic insuffciency, and chronicdiarrhea will find this formula a good complement to their therapeuticprograms. This supplement has been administered to animals withdigestive problems where digestive enzymes may be lacking or notproperly functioning therefore causing problems in assimilation.

Please check our website for full list ofingredients.www.animalnecessity.com

Product Description

Natural support for optimal liver healthSuggested use with Digestin Vet to help improve digestionAids in liver, gallbladder, and kidney functionSuggested use with Alpha Lipoic Acid for maximumantioxidant hepatic support

Promotes digestive healthProvides probiotics which helps maintain beneficial bacterial flora of thedigestive tractAids in the production of red blood cellsAppetite stimulantSuggested use with Artichoke and Milk Thistle for liver and digestive support

5-25 lbs 1/2 tablet

25-50 lbs 1 tablet

50-100 lbs 2 tablets

100-200 lbs 4 tablets

Baseline Dosages

5-25 lbs ½ tablet, every other day

25-50 lbs 1 tablet, every other day

50-100 lbs 1 tablet, daily

100-200 lbs 2 tablets, daily

Baseline Dosages

List of Ingredients

Alpha lipoic (ALA) is a fatty acid that acts as a powerful water and fat-soluble antioxidant found in the body intrace amounts. ALA increases the body’s production of glutathione, the body’s most important endogenousantioxidant. ALA is known for its ability to help neutralize cell damaging free radicals and helps dissolve toxicsubstances in the liver.(1) Imbalance of the glutathione redox cycle contributes to cataractogenesis and ALA hasbeen shown to protect lenses from oxidative stress that causes cataracts.(2) This universal antioxidant helps tobenefit diabetic canine patients as it promotes normal insulin sensitivity and glucose metabolism, though actuallevels of insulin and glucose may not change.(3) Note: It is not safe in cats at a dose higher than 30 mg/day.1, 2, 3 Please visit www.animalnecessity.com for references

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ALPHA LIPOIC ACID

List of Ingredients

Alpha Lipoic Acid 50 mg

NUTRITION AMOUNT PERSERVING

Product Description

Protects the body against cell damage in conditions of oxidative stress Boosts Glutathione - increases the body's production of glutathione,which helps dissolve toxic substances in the liverSupports normal liver enzyme levelsPromotes normal glucose metabolismSuggested use with Artichoke & Milk Thistle for hepatic support

5-25 lbs ½ capsule

25-50 lbs 1 capsules

50-100 lbs 2 capsules

100-200 lbs 3 capsules

Baseline Dosages

NEUROPLEX

The supplement Neuro-plex combines both: Neuroprevin™ and PolicosanolPlus® which has been shown toenhance nerve formation and then promote the maintenance of these nerves (1). Evidence supports its use as afunctional ingredient for nerve regeneration as well as neuroprotection from the effects of environmental pollutantsand aging. If this supplement is used as part of a daily dietary routine, it can serve as a prophylactic against theonset of neurodegenerative diseases. 1 Weeks BS, Perez P. PolicosanolPlus® and NeuroprevinTM Enhance Neurite Regeneration and Prevent Neurite Degeneration: A DietarySupplement for Nerve Repair, Prevention and Reduction of Neurodegenerative Disorders. Journal of the American NutraceuticalAssociation, Vol. 9, No. 2: pp

Under 100 lbs 1 capsule

100-200 lbs 2 capsules

Baseline Dosages List of Ingredients

Neuro-plex proprietary blendRiboflavin (Vitamin B2)Folate (as folic acid)

315 mg1 mg

400 mcg

NUTRITIONAMOUNT PER

SERVING

Enhance nerve regeneration

Helps to prevent neurodegeneration

Helps to reduce nerve damage upon stress or injury

Product Description

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PROTOCOL BASED APPROACHAnimal Necessity launched in 2006 with the mission to set the standard for naturalanimal healthcare, and in 2012 we continue to stay true to that focus. Our staffveterinarians and Scientific Advisory Team members remain dedicated to developingthe most comprehensive and practical protocols for our clients.

We believe that the best quality healthcare is only achieved by a holistic approach thattakes more than simply adding supplements to an animal’s diet. For that reason westrive to meet the individual needs of every client and offer our nutritional consultationsfree of charge. For testimonials or examples of protocols in use, please visit our websiteat: www.animalnecessity.com

The baseline dosages in this catalog are calculated by animal weight and can be dispensedto most species as a preventative or maintenance dose. For individual cases or specificdisease support questions, please set up a consultation with one of team members byemailing us at: info@animal-necessity.com.

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PROTOCOL BASED APPROACH

OTHER TOP PRODUCTS

1. Pinebark Extract with Pureway C ®

2. Omega-3 Max3. Spirulina4. Vinpocetine5. Vitamin D36. Vitamin E

AN IMA L N E C E S S I T Y, L LC330W 38th Street, Suite # 801

New York, NY 10018Toll Free: 1-800-721-1310

Email: info@animal-necessity.com www.animal-necessity.com