anidulafungin cost effective despite high acquisition costs
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PharmacoEconomics & Outcomes News 632 - 9 Jul 2011
Anidulafungin cost effectivedespite high acquisition costs
According to researchers from Australia,anidulafungin is cost effective for the treatment ofinvasive candidiasis.
The researchers used a decision analytic model tocompare the cost effectiveness of anidulafungin versusfluconazole from an Australian hospital perspective.While anidulafungin was substantially more expensivein terms of acquisition costs ($A695.00 vs $7.20 pervial) and, as a result, more expensive in terms of totalcosts per successfully treated patient ($74 587 vs$60 945), it was associated with a lower mortality rate inclinical trials. Anidulafungin was estimated to save anaverage of 0.53 additional life-years versus fluconazole.Anidulafungin was therefore associated with anincremental cost-effectiveness ratio (ICER) of $25 740per life-year saved, which, the researchers suggest, is"below the implicit ICER threshold for Australia". Theyconclude that, this finding emphasizes that thetraditional cost-containment concept, which is primarilybased on superficial cost considerations, in particulardrug acquisition costs, should not be the soledeterminant in the choice of antifungal agent."Neoh CF, et al. Cost-effectiveness analysis of anidulafungin versus fluconazole forthe treatment of invasive candidiasis. Journal of Antimicrobial Chemotherapy : 30May 2011. Available from: URL: http://dx.doi.org/10.1093/jac/dkr186 803056664
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PharmacoEconomics & Outcomes News 9 Jul 2011 No. 6321173-5503/10/0632-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved