anidulafungin cost effective despite high acquisition costs

1
PharmacoEconomics & Outcomes News 632 - 9 Jul 2011 Anidulafungin cost effective despite high acquisition costs According to researchers from Australia, anidulafungin is cost effective for the treatment of invasive candidiasis. The researchers used a decision analytic model to compare the cost effectiveness of anidulafungin versus fluconazole from an Australian hospital perspective. While anidulafungin was substantially more expensive in terms of acquisition costs ($A695.00 vs $7.20 per vial) and, as a result, more expensive in terms of total costs per successfully treated patient ($74 587 vs $60 945), it was associated with a lower mortality rate in clinical trials. Anidulafungin was estimated to save an average of 0.53 additional life-years versus fluconazole. Anidulafungin was therefore associated with an incremental cost-effectiveness ratio (ICER) of $25 740 per life-year saved, which, the researchers suggest, is "below the implicit ICER threshold for Australia". They conclude that, this finding emphasizes that the traditional cost-containment concept, which is primarily based on superficial cost considerations, in particular drug acquisition costs, should not be the sole determinant in the choice of antifungal agent." Neoh CF, et al. Cost-effectiveness analysis of anidulafungin versus fluconazole for the treatment of invasive candidiasis. Journal of Antimicrobial Chemotherapy : 30 May 2011. Available from: URL: http://dx.doi.org/10.1093/jac/dkr186 803056664 1 PharmacoEconomics & Outcomes News 9 Jul 2011 No. 632 1173-5503/10/0632-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved

Upload: lyanh

Post on 17-Mar-2017

215 views

Category:

Documents


3 download

TRANSCRIPT

Page 1: Anidulafungin cost effective despite high acquisition costs

PharmacoEconomics & Outcomes News 632 - 9 Jul 2011

Anidulafungin cost effectivedespite high acquisition costs

According to researchers from Australia,anidulafungin is cost effective for the treatment ofinvasive candidiasis.

The researchers used a decision analytic model tocompare the cost effectiveness of anidulafungin versusfluconazole from an Australian hospital perspective.While anidulafungin was substantially more expensivein terms of acquisition costs ($A695.00 vs $7.20 pervial) and, as a result, more expensive in terms of totalcosts per successfully treated patient ($74 587 vs$60 945), it was associated with a lower mortality rate inclinical trials. Anidulafungin was estimated to save anaverage of 0.53 additional life-years versus fluconazole.Anidulafungin was therefore associated with anincremental cost-effectiveness ratio (ICER) of $25 740per life-year saved, which, the researchers suggest, is"below the implicit ICER threshold for Australia". Theyconclude that, this finding emphasizes that thetraditional cost-containment concept, which is primarilybased on superficial cost considerations, in particulardrug acquisition costs, should not be the soledeterminant in the choice of antifungal agent."Neoh CF, et al. Cost-effectiveness analysis of anidulafungin versus fluconazole forthe treatment of invasive candidiasis. Journal of Antimicrobial Chemotherapy : 30May 2011. Available from: URL: http://dx.doi.org/10.1093/jac/dkr186 803056664

1

PharmacoEconomics & Outcomes News 9 Jul 2011 No. 6321173-5503/10/0632-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved