Analytical & Measuring Instruments

Pocket Reference

SHIMADZUSCIENTIFIC INSTRUMENTS & EQUIPMENT

Introducing powerful performance for the world

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Quality recognized worldwide

Shimadzu Corporation is committed to helping scientists like you

do your job better. Founded in 1875, Shimadzu has a distinguished

history of innovation built on the foundation of contributing to

society through science and technology. This history is rivaled only

by the passion we have for the future as we continue to introduce

new solutions, faster than ever, for R&D and quality control in

such markets as pharmaceuticals, food products, semiconductors,

automotive, clinical, mining and metals, petrochemical, life sciences,

and environmental. In this ever-changing global landscape of industry,

Shimadzu will help you succeed by providing you “total solutions”

with the products and services you need.

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Introducing our new products

LCMS-8060

MALDI-7090

HMV-G

i-Series

RF-6000

GCMS-TQ8040

ICPE-9810

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Pocket Reference

Contents

6 Chromatographs

18 Delivering New Technology for Life Science

26 Spectroscopy Products

32 X-Ray Spectroscopic/ Surface Analysis Apparatus

35 Laboratory and On-line Total Organic Carbon (TOC) and Nutrient Analyzers

38 Testing Instruments for Physical Properties

45 UniBloc Family of Balances

ChromatographsChromatography is the standard analytical separation technology

used for quantitative analysis. Ever since Shimadzu developed its

first gas chromatograph in 1956, we have continued to broaden our

chromatography lineup, by providing liquid chromatographs and

systems combined with mass spectrometers. Meanwhile, we have

developed a variety of application-specific systems designed for

customers in a wide range of industries, including pharmaceutical,

environmental, food and beverage, and petrochemical.

Shimadzu also provides data processing and data management

software to actively help customers comply with various regulatory

requirements, including GxP and FDA 21 CFR Part 11.

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UHPLC HPLC/UFLC LC-MS/MS LC-MS

GC GC-MS/MS GC-MS

Ultra High Performance Liquid Chromatograph (UHPLC)Shimadzu’s Nexera systems deliver superior, real-world performance across a wider application range while delivering unparalleled flexibility and reliability in HPLC/UHPLC analyses. The primary system, Nexera X2, is optimized to enable analysis at pressures up to 19,000 psi without compromising performance and data quality. The modular design of the Nexera series enables users to build application-specific systems. These include the high-resolution Nexera SR, which is equipped with the SPD-M30A PDA detector; a method scouting system capable of automatically investigating up to 96 combinations of mobile phases and columns; and Nexera-e, a comprehensive 2D LC.

New this year is the Nexera UC (Unified Chromatography), the world’s first fully automated system that combines on-line SFE and SFC in a single flow path. This unique system enables automatic extraction of up to 48 samples followed by seamless transfer to SFC/MS for high-sensitivity detection of targets by mass spectrometry.

Products

• Nexera X2 • Nexera SR • NEW Nexera UC (SFE-SFC)• Nexera XR • Nexera MP • Nexera-e• Nexera Method Scouting • Nexera Quaternary

Nexera UCApplicationsPharmaceuticalsFood & BeverageChemicalEnvironmental Biotechnology

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NEW

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Nexera MP Front-end UHPLCThe Nexera MP Ultra High Performance Liquid Chromatograph is the ideal front-end system for all LC/MS platforms. It utilizes the SIL-30ACMP Multiplate Autosampler, which features high-speed injection (7 seconds) to significantly improve throughput in multi-sample processing, trace quantity injection repeatability values, and near-zero carryover (0.0015% or less). To meet throughput demands, up to 6 microtiter plates can be loaded, enabling a maximum of 2,304 samples to be analyzed continuously.

A system for high-speed, high-accuracy analysis of multiple analytes can be constructed by combining the Nexera MP with an ultra-high-performance mass spectrometer, such as the triple quadrupole LCMS-8030/8040/8050/8060, or the single quadrupole LCMS-2020.

Products

• Nexera MP

Nexera MPApplicationsPharmaceuticalsFood & BeverageEnvironmental Biotechnology

High Performance Liquid Chromatograph (HPLC)HPLC systems are able to quantitatively analyze substances in mixtures containing multiple ingredients by separating and detecting target substances. They are also able to purify specific substances once they are separated. The Prominence is a modular HPLC system, which can be configured to create the optimal system for specific customer applications, while the i-Series LC-2030 and LC-2040 are completely integrated HPLC systems designed for innovative, intuitive, and intelligent operation. Shimadzu also offers a wide variety of other application-specific systems, such as automated sample pretreatment systems for separating metabolites contained in pharmaceuticals or biological samples, residual pesticide sample pretreatment systems for separating pesticides, and systems for analyzing organic acids and amino acids.

Products

• Prominence (Modular HPLC) • Prominence nano (Nano-flow LC)• NEW i-Series (Integrated HPLC) • 2D Micro-HPLC System

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i-SeriesApplicationsPharmaceuticalsFood & BeverageEnvironmental Biotechnology

NEW

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LabSolutionsChromatography SoftwareFaster, more efficient management of LC/GC and LC/MS instruments and data is essential. To address such requirements, Shimadzu offers a scalable range of LabSolutions software packages, which feature an innovative operating environment and provide complete data management to ensure secure information. All setup and quantitative functions can be performed on one screen and wizards lead the user through the process. It allows customized applications under software control and provides universal reports for QA/QC verification and GLP/GMP compliance automatically. The system administration includes user administration, system policy setting, log browser, and audit trails, which support 21 CFR Part 11 compliance.

From LabSolutions Lite, offering control of one system, and LabSolutions LC/GC and DB, enabling any combination of four LC/GC systems to be connected for simultaneous use, to the networked LabSolutions C/S, Shimadzu can provide a solution for any laboratory environment. * Capabilities vary according to the platform

Products

• LabSolutions Lite • LabSolutions DB (Database)• LabSolutions LC/GC • LabSolutions C/S (Client/Server)

LabSolutionsApplicationsPharmaceuticalsFood & BeverageEnvironmental Biotechnology

Triple Quadrupole Mass SpectrometerThe newest model in the Ultra-Fast Mass Spectrometry series, the LCMS-8060 incorporates Shimadzu’s proprietary ultrafast technologies (UF Technologies) to enable a polarity switching time of 5 msec, a data acquisition scan speed of 30,000 u/sec, and ultra-fast MRM measurements up to 555 ch/sec. A redesigned UF-Qarray ion optical system offers outstanding ion sampling efficiency and ion focusing. Combined with a robust design and easy maintenance, the LCMS-8060 is the ideal solution for better data quality and higher throughput for a wide array of challenging and routine applications.

Other models include the LCMS-8050, which provides both best-in-class sensitivity and excellent quantitation performance; the LCMS-8040, which offers enhanced sensitivity for complex matrices and difficult analytes; and the rugged LCMS-8030, built for routine quantitative analysis in challenging matrices. Combine any system with Shimadzu’s world-leading UHPLC systems for an unmatched level of performance.

Products

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ApplicationsEnvironmentalPharmaceuticalsFood & BeverageClinicalChemical

LCMS-8060NEW

• NEW LCMS-8060 • LCMS-8050• LCMS-8040 • LCMS-8030

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Single Quadrupole Liquid Chromatograph-Mass SpectrometerBuilding an LC/MS system that employs an MS as an LC detector can effectively reduce the limitations of LC analysis. The qualification performance of spectrometers is useful for detecting impurities in overlapped peaks.Utilizing patented ultrafast (UF) technology, Shimadzu’s LCMS-2020 mass spectrometer offers faster measurements and higher detection sensitivity for quicker and more accurate detection of trace impurities in a variety of applications. It features an ultrafast scanning speed of 15,000 u/sec, without sacrificing sensitivity or resolution, unsurpassed 15 msec polarity switching speed, for the most data without peak deterioration in a single injection, and multiple Ionization options (ESI, APCI, and DUIS). Innovative ion optics provides greater sensitivity than any other single quadrupole analyzer, while easy system maintenance enables greater uptime and usability.

Products

• LCMS-2020 (ESI standard)• DUIS-2020 (Optional ionization, simultaneous ESI and APCI ionization)• APCI-2020 (Optional ion source)

LCMS-2020ApplicationsPharmaceuticalsFood & BeverageEnvironmental Biotechnology

Hybrid High Performance Liquid Chromatograph-Mass SpectrometerThe LCMS-IT-TOF is a system which combines an ion-trap mass spectrometer (IT) with a time-of-flight mass spectrometer (TOF). The ion trap offers MSn capability and the TOF provides high-resolution and highly accurate MS analysis capability. This combination offers the diverse analysis information required for effective structure analysis in such research areas as impurity analysis, metabolomics profiling and biomarker discovery. In addition, Shimadzu offers user-friendly, application-specific software products to maximize the performance of the LCMS-IT-TOF.

Products

• LCMS-IT-TOF• Nano ESI Interface (Optional)• APCI, APPI Ion Source (Optional)• Software Packages: Formula Predictor, Profiler, MetID Solution

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LCMS-IT-TOFApplicationsMetabolomicsProteinFood & BeverageNatural Products

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Gas ChromatographGas chromatographs analyze samples qualitatively and quantitatively. After evaporation of the sample, the different components are separated on a column and subsequently sent to the detection system. By comparing with samples of known concentrations, the concentration in an unknown sample can be determined. The GC-2010 Plus enables reliable trace analysis utilizing detectors such as FID and FPD that feature best-in-class sensitivity. Newly introduced Advanced Flow Technology reduces analysis times, provides enhanced chromatographic resolution, and enables application-specific configurations, such as multidimensional GC, backflush, and detector splitting and switching systems, without compromising performance. The GC-2014 can be used for both capillary and packed column analysis. Integrating the new barrier discharge ionization detector (BID-2010 Plus), a novel universal detector that incorporates plasma technology, Tracera GC makes it possible to reveal trace components not easily detected by other devices.

Products

• GC-2010 Plus (Capillary GC)• GC-2014 (Capillary/Packed GC)• GC-8A (Simple GC)• Tracera• Advanced Flow Technology Devices (Multidimensional GC/Heart-cut/ Backflushing/Detector Splitting/Detector Switching)

GC-2010 PlusApplicationsPetrochemicalEnvironmentalFlavor & FragranceBiofuels

System GC ProgramThe updated System GC program provides customers with application-specific GCs that offer a complete solution for a laboratory’s specific needs. The modular GC-2014 is the workhorse of the system GC program. It features the ability to hold 4 detectors, 12 channels of Advanced Pressure Control, 16 time programmable relays, and a large oven that can accommodate many columns. Each system is customized with a GC, valves, an inert treatment for the analytical flow path, and installation and start-up supplies. In addition, each system is shipped with proof of performance, QA/QC, and a field test standard.

Products

• System GC

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System GCApplicationsNatural GasTransformer GasGreenhouse GasBiofuelsBiomass Feedstock Research

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Triple Quadrupole Gas Chromatograph Mass SpectrometerFeaturing Smart Productivity, Smart Operation, and Smart Performance, the GCMS-TQ8040 is the most accurate, cost-effective and user-friendly GC-MS/MS available. The system enables analysis of 400+ compounds in a single MRM run without sacrificing sensitivity or selectivity while the MRM Optimization Tool seamlessly selects and optimizes MRM transitions for multiple compounds in a single sequence. Other features include high-speed MRM analysis of up to 800 transitions per second, high-speed scanning control at 20,000 u/second, Scan/MRM analysis mode, Automatic Adjustment of Retention Times (AART), and quick, stress-free maintenance.

The GCMS Smart Database Series is comprised of separate databases for analyzing pesticides, forensic toxicological substances, metabolites and environmental pollutants. Each database includes hundreds of related compounds with optimized transitions and collision energies, CAS registry numbers and retention indices (RI). The software series supports simultaneous high-sensitivity analysis of samples using GC-MS/MS, eliminating the need to configure complicated analysis conditions.

Products

• NEW GCMS-TQ8040

GCMS-TQ8040ApplicationsFood TestingEnvironmentalLife ScienceForensics/Toxicology

NEW

Gas Chromatograph-Mass Spectrometer (GCMS)Shimadzu’s quadrupole GCMS systems contribute to increased sensitivity and higher productivity in the laboratory. A newly-designed electric control platform provides best-in-class scanning speed and the advanced scanning speed protocol (ASSP) ensures sensitivity improvement at high-speed data scanning. Features for shorter analysis time and easy maintenance increase efficiency. Library search using Linear Retention Indices and Automatic Adjustment of Retention Times (AART) make identification easy and reliable. In addition to standard models with electron ionization (EI), Shimadzu also offers models with Chemical Ionization (positive and negative) for enhanced selectivity as well as sensitivity. Options/accessories include a direct sample introduction system, a Thermal desorption system (TD-20), multiple autosamplers, a cooled PTV (temperature programmable injector) (OPTIC-4), a Pyrolyzer (Py-3030) and Shimadzu Advanced Flow Technologies for Heart-Cut GC/GCMS. Shimadzu’s fast quadrupole with up to 100 scans/s enables the system to perform Comprehensive GCMS, using thermal modulation (Zoex loop modulator) for narrowest peak shape and highest sensitivity.

Products

• GCMS-QP2010 Ultra, available models: EI, EI/CI, EI/CI/NCI (upgradable)• GCMS-QP2010 SE (Standard EI)• Twin Line GCMS

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MDGC/GCMS-QP2010 UltraApplicationsEnvironmentalFlavor & FragrancePetroleum IndustryForensicsRoHS/WEEE/ELV

Delivering New Technology for Life ScienceShimadzu is focused on developing new tools by integrating novel

chemistry with innovative technology to help accelerate life

science research.

Whether it is an experiment for protein expression, characterizing

differences in metabolism studies, or imaging tissue with mass

spectrometry, Shimadzu can help you discover more about your

biological samples.

TOF-MS Processors UV Sequencers18

MALDI-TOF Mass SpectrometryOffering unparalleled MS/MS resolution and excellent mass accuracy, Shimadzu’s high-throughput, high-energy, high-resolution MALDI-7090 tandem mass spectrometer achieves a new level of MALDI-TOF MS performance. It combines Shimadzu’s extensive MALDI TOF-TOF expertise with novel patented technology to provide ultimate performance in identification and structural characterization of biomolecules. It features 2 kHz acquisitions in all modes, a high-resolution ion gate, low and high-energy fragmentation, a 10 plate sample loader, and a multi-user software environment.The AXIMA Assurance linear MS is ideal for high-throughput QA/QC environments and simple, yet accurate mass measurements. A linear/reflectron MS, the AXIMA Confidence incorporates the patented curved field reflectron (CFR) for flexibility and reliable, simple MS/MS. The AXIMA Performance is a TOF2 MS featuring high-energy CID and excellent sensitivity. The only commercial MALDI-QIT-TOF MS, the AXIMA Resonance combines the MSn capabilities of an ion trap and the high mass accuracy abilities of time-of-flight.

Products

• MALDI-7090 (TOF-TOF)• AXIMA Assurance™ (Linear MALDI MS)• AXIMA Confidence™ (Linear/Reflectron MALDI MS)• AXIMA Performance™ (TOF-TOF)• AXIMA Resonance™ (MALDI QIT-TOF)

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ApplicationsProteome AnalysisPolymer AnalysisStructural AnalysisIdentification of MicroorganismsQA/QC AnalysisBiomarker DiscoveryStructural Analysis of Glycans

MALDI-7090

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Megadalton MALDIMass SpectrometerThe solution for ultrahigh mass applications, the MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI-TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa. Ideally suited for such applications as antibody characterization, protein complexes characterization, therapeutic protein aggregates and high mass MALDI imaging, features include:

• Ultrahigh sensitivity• Detects macromolecules up to 1,500,000 Da• Stabilization of molecule using crosslinking reagent kits• Fast, specific stabilization of protein interactions• Also applicable for low mass applications• Apple® iPod touch control

Products

• MegaTOF

MegaTOF™

ApplicationsAntibody CharacterizationProtein Complexes CharacterizationTherapeutic Protein AggregatesHigh Mass MALDI ImagingInhibitors of Protein-protein Interactions

Biomarker Discovery PlatformThis platform combines the unique harvesting capabilities of Nanotrap Particles (Ceres Nanosciences) with reliable AXIMA MALDI MS² detection and powerful, integrated Progenesis MALDI discovery/validation informatics (Nonlinear Dynamics). This fully integrated workflow speeds up discovery, identification, and validation, and makes early disease detection possible. Nanotrap advantages include:

• One step fractionation and enrichment• Bind low-level compounds• Exclude undesired molecules• Automated sample processing• Protect trapped analytes• Simplified screening and ID

Nanotrap Particles can also be utilized in research targeting the discovery and quantification of known low abundance analytes present in a range of complex biofluid matrices, including cell culture supernatant, serum, urine, cerebrospinal fluid, and environmental water samples.

Products

• AXIMA Nanotrap Biomarker Discovery Platform

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Nanotrap®

ApplicationsBiomarker DiscoveryMetabolomicsClinical Diagnostics ResearchToxicology

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Automated ProteinSample PrepThe Perfinity Workstation is a fully-integrated online mass spec sample preparation workstation, combining the selectivity of immunoassay approaches with the resolution of high performance liquid chromatography. It utilizes multiple proteomic approaches to rapidly and reproducibly perform affinity selection, buffer exchange, trypsin digestion, desalting of the sample and reverse phase LC analysis.

The Perfinity Integrated Digestion Platform (iDP) is a simplified platform automating the same proteomics workflow steps except for affinity selection. Perfinity IDP dramatically reduces sample prep times while providing consistent, highly reproducible results.

• Serum to purified peptides in < 10 min.• Three-day workflow complete in under one hour• High-quality, reproducible proteolysis data (CVs < 10%)• Hands free operation–fully automated• Significant reduction in cost per sample• Easily customizable

Products

• Perfinity Workstation• Perfinity iDP

Perfinity WorkstationApplicationsAssay DevelopmentDrug DevelopmentProtein PurificationBiomarker Screening

TOF MS Apparatus(CHIP/AccuSpot)The CHIP-1000 precisely and accurately delivers pico liter volumes of reagent to a target surface using piezo-electric technology. Major application areas include direct MS/MS analysis of proteins blotted on membrane, direct protein identification of western blotting, and printing MALDI matrices onto histological sections.

The AccuSpot™ is a high-capacity LC spotting robot specifically designed for MS analysis which supports collection of up to 9 Shimadzu MALDI micro-filter plate format targets as well as ABI and Bruker formats. The AccuSpot uses a “half-contact” spotting method to prevent damage to the plate or probe tip.

Products

• CHIP-1000 (Unique device for delivering reagents on a micro-scale)• AccuSpot™ (High-capacity LC spotting system)

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CHIP-1000 AccuSpotApplicationsMS Tissue Imaging

ApplicationsHigh-Throughput LC-MALDI Analysis

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Micro-volumeSpectrophotometerShimadzu’s micro-volume BioSpec-nano is a low-maintenance micro-volume spectrophotometer designed for the modern life science laboratory. Its easy-to-use design and superior detection limits, up to 10 times better compared to the competition, make it the perfect instrument for quantitation of DNA, RNA, protein analysis, and photometric measurements.

• Ultra-small sample volumes (1 µL to 2 µL samples)• Easy operation with “Drop-and-Click” analysis • Rapid analysis times — Easy sample mounting and automated cleaning enable a rapid 3-second analysis time and a 10-second cycle time between samples • Optional 5mm pathlength cell• Photometric analysis (up to 8 wavelengths) • Dedicated software allows ease of quantitation of DS/SS DNA and labeled/unlabeled proteins

Products

• BioSpec-nano

BioSpec-nanoApplicationsQuantitation Analysis for DNA and RNA Nucleic AcidPhotometric MeasurementProtein Analysis

Automated Protein PeptideSequencerPPSQ-31B/33B systems use Edman degradation to cleave amino acids, one at a time, from the N-terminals of proteins, then derivatize them to PTH amino acids and determine the sequence of amino acids using HPLC. PPSQ-31B/33B systems are useful for sequencing analysis of organism species with no existing database, sequencing the amino acids from N-terminals on proteins actually functioning within a biological organism, or confirming the sequence of amino acids from N-terminals on artificially synthesized proteins such as E. coli. PPSQ and HPLC systems are operated using a single software program, enabling easier sequence analysis of proteins and peptides, and making it extremely easy to specify analytical conditions or view results.

Products

• PPSQ-31B/33B (Protein sequencing)

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PPSQ-31B/33BApplicationsProtein Sequencing via Automated Edman Degradation Chemistry

Spectroscopy ProductsSpectroscopy is a general term for analytical methods utilizing ultraviolet

(UV), visible (VIS), infrared (IR), or near infrared (NIR) light to analyze

substances. Major types include absorption spectroscopy, where the

absorption of specific wavelengths resulting from different molecular

structures is measured, atomic absorption spectroscopy, where substances

are first atomized, then the absorption of the atomic vapor is measured,

fluorescence spectroscopy, where a specific wavelength is absorbed and

then the emission of a different wavelength is measured, and inductively

coupled plasma atomic emission spectroscopy (ICP-AES), where substances

are subjected to high-temperature excitation and characteristic light

emissions from elements are measured. Instruments measuring absorption,

atomic absorption or fluorescence are comprised primarily of light sources,

monochromators and detectors. In emission spectrometers, the sample is

introduced into the light source. Shimadzu’s product line includes UV-VIS-

NIR spectrophotometers, Fourier transform infrared spectrophotometers,

atomic absorption spectrophotometers, and ICP spectrometers.

UV FTIR AA

26Spectrofluorophotometer ICP

UV-Vis SpectrophotometerShimadzu has been manufacturing UV-Vis spectrophotometers for more than 60 years, and excels at providing instruments that meet scientists’ needs for ruggedness, ease of use, validation and applications. This flexibility enables spectroscopists in virtually any laboratory, from pharmaceutical, materials science, and environmental to academic research, food & beverages, and life sciences, to select the instrument best suited to their application. Options include the monitored single-beam UV-1280 for routine laboratory analyses; robust, high-resolution UV-1800; single and double monochromator UV-2600/2700, which feature a wealth of accessories/software packages to address routine analyses as well as demanding research applications; and the three-detector UV-3600 Plus/SolidSpec-3700 UV-Vis-NIR systems, which provide the utmost in sensitivity and resolution across the entire wavelength range.

Products

• NEW UV-3600 Plus/SolidSpec-3700 (UV-VIS-NIR spectrophotometers)• UV-2600/2700 (UV-VIS spectrophotometers with variable bandwidth)• UV-1800 (Multi-purpose spectrophotometer)• NEW UV-1280 (Standalone spectrophotometer with bio functions)

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ApplicationsPharmaceuticalsBiotechnologyWater QualityNanotechnologySolar Cells

UV-3600 PlusNEW

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FTIR SpectrophotometerFourier transform infrared (FTIR) spectrophotometers are primarily used to predict (qualitate) the structure of organic compounds. When molecules are irradiated with infrared light, the infrared wavelengths corresponding to the vibrational energy between the constituent atoms are absorbed. Infrared spectroscopy evaluates the degree of this absorption to quantify or predict the structure of compounds.

Combining high speed (up to 20 spectra/sec acquisitions), best-in-class 60,000:1 S/N ratio, and excellent resolution (0.25cm−1) with enhanced expandability and easy-to-use software, the IRTracer-100 quickly and easily obtains high-quality data for a wide range of samples. It features a stable, airtight interferometer that incorporates a built-in automatic dehumidifier, while the patented Advanced Dynamic Alignment provides enhanced stability and shorter warm-up times. Designed with the teaching and general research laboratories in mind, the IRAffinity-1S offers full functionality for all FTIR techniques in a compact design.

Products

• IRTracer-100• IRAffinity-1S

IRTracer-100ApplicationsPharmaceuticalsOrganic ChemistryPolymersEnvironmentalRoHS / WEEE / ELVNanotechnologySolar Cells

SpectrofluorophotometerCompared to absorption methods, fluorescence spectroscopy is ten to several thousand times more sensitive. This allows analyzing picogram to nanogram-sized samples with excellent results. Fluorescence can also be used to identify specific molecules in a complex spectral background. This technique is widely used in pharmaceuticals and pharmacology, biochemistry, food science, environmental monitoring and chemical analyses.

Incorporating intuitive LabSolutions RF software, and featuring a wealth of accessories, the RF-6000 delivers the ultimate in performance for a range of applications. It features the highest sensitivity and highest signal-to-noise ratio (SNR) in its class (SNR ≥1,000 RMS and ≥350 peak-peak); high-speed 3D scanning of 60,000 nm/min; and an extended upper wavelength range to 900nm. The Xenon lamp features a 2,000 hour service life and auto alignment technology for less frequent and more user-friendly maintenance. LabSolutions RF software features sophisticated, yet easy-to-use functionality ranging from standard fluorescence to 3D measurements of fluorescence spectra at any wavelength interval.

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ApplicationsBiotechnologyEnvironmentalClinicalPharmaceuticals

RF-6000NEW

Products

• NEW RF-6000 Spectrofluorophotometer

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Atomic AbsorptionSpectrophotometerSince introducing its first atomic absorption spectrophotometer in 1968, Shimadzu has continued to lead the field of inorganic compound analysis. Shimadzu now offers the AA-7000. This flexible system provides users with best-in-class sensitivity, and can be customized into a low-cost single-purpose model and a fully automatic general-purpose system. The AA-7000 also employs various safety features, and it is the world’s first AA spectrophotometer that employs an automatic quench function, which works in case of detection of an earthquake. The WizAArd workstation software is also improved and can be linked to CLASS-Public Agent software to provide compliance with FDA 21 CFR Part 11.

ApplicationsEnvironmentalAgriculture & FoodWater QualityRoHS/WEEE/ELV

Products

• AA-7000F (Flame type)• AA-7000G (Furnace type)• AA-7000F + GFA-7000 (Optional/ Flame and furnace type)• AA-6200 (Affordable AAS)

AA-7000

Inductively Coupled Plasma Atomic Emission Spectrometer (ICP-AES)Featuring user-friendly software and a proprietary design, the simultaneous ICPE-9800 series instruments enable sensitive, high-speed simultaneous analysis of multiple elements regardless of concentration levels. A vertically oriented plasma torch with dual view (axial/radial) capabilities achieves the ideal combination of sensitivity and dynamic range. Eco Mode and a mini-torch system significantly minimize argon gas consumption, resulting in substantial cost savings. Easy-to-use, 21 CFR compliant software helps users optimize methods and enables a smooth analysis process with a Method Development Assistant, Automatic Wavelength Selection, and a Diagnosis Assistant. Numerous accessories are available so users can customize a system to meet their specific application needs.

Products

• ICPE-9800 Series

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ICPE-9800ApplicationsEnvironmentalPetroleum IndustryMetalsSemiconductorsRoHS/WEEE/ELVSolar Cells

NEW

X-Ray Spectroscopic / Surface Analysis ApparatusX-ray spectroscopic/surface analysis apparatus utilize X-rays or electron

beams to measure and analyze constituent elements. This product category

includes EDX, XRF and MXF systems, which detect X-ray fluorescence to

identify the type of elements contained in samples (qualitative analysis)

and measure the concentration of each (quantitative analysis), and

XRD systems, which analyze the diffraction of X-rays to learn about the

crystalline structure of samples.

In particular, Shimadzu’s EDX systems provide an easy way to measure

the six substances (five elements) regulated by the RoHS/ELV directives in

Europe. As a result, Shimadzu has gained extensive experience providing

EDX systems to customers for the screening of electrical/electronic parts

or automotive parts to determine to what degree they contain these

regulated substances.

32XRD EDX, XRF, MXF

X-ray DiffractometerWhen a sample is irradiated with X-rays, a variety of signal types can be obtained. Of those signals, X-ray diffraction reveals the crystalline state of samples. Analyzing these diffracted X-rays allows learning about the crystalline structure of samples. XRD series spectrometers are powder X-ray diffractometers used primarily to identify constituents of powder (multi-crystalline) samples (qualitative analysis) and determine their concentration (quantitative analysis). For example, they can be used to precisely determine the lattice constant, crystallite size, lattice distortion or degree of crystallization of released silicic acid or asbestos by qualitatively and quantitatively analyzing the samples and also numerically analyzing their diffraction X-ray profile. Furthermore, numerous optional products are available to allow other analytical applications such as observing changes in crystalline structure as temperature varies or measuring residual stresses.

Products

• XRD-6100 (Vertical goniometer type varying x-ray angle of incidence and angle of diffraction)• XRD-7000 (Horizontal goniometer type for measuring soluble or loose powder samples, electronic materials, stress distributions in large automotive or other samples, and many other applications)

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XRD-7000ApplicationsFerrous & Non-Ferrous Metals PharmaceuticalsPolymers & Materials SemiconductorsSolar Cells

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X-ray Fluorescence SpecrometerX-ray fluorescence spectrometers irradiate samples with X-rays and measure the characteristic wavelengths or energy in the secondary X-rays (X-ray fluorescence) generated from the sample. They are able to identify the type of constituent elements in samples (qualitative analysis) and measure the concentration of each (quantitative analysis). Since samples can be analyzed non-destructively and without contacting the sample, X-ray fluorescence spectrometers can be used for a wide range of applications, regardless of whether the sample is a solid, liquid, powder or other form. Shimadzu offers two types of X-ray fluorescence spectrometers – wavelength dispersive systems, which provide outstanding detection of trace substances, and energy dispersive systems, which are compact and able to analyze samples easily and rapidly.

Products

• Energy Dispersive X-Ray Fluorescence Spectrometers NEW EDX-7000/8000 EDX-LE (Designed for WEEE, RoHS, and ELV applications) • Wavelength Dispersive X-Ray Fluorescence Spectrometers XRF-1800 (Top-of-the-line all-in-one type sequential analyzer)

ApplicationsFerrous & Non-Ferrous Metals PetroleumAgriculture & FoodSemiconductorsRoHS/WEEE/ELVNanotechnologySolar Cells

EDX-7000/8000NEW

Laboratory and On-line Total Organic Carbon (TOC) and Nutrient AnalyzersShimadzu is the world leader in the manufacture of TOC analyzers. Our

state-of-the-art instruments maximize sensitivity, oxidation efficiency, and

productivity, making them your ideal choice for monitoring environmental

samples or pharmaceutical cleaning validations. Addition of a nitrogen

module enables rapid, safe, and cost-effective analysis for organic and

total nitrogen. Add an optional solid sample module to determine organic

and inorganic carbon in soil and filter media. Our highly advanced on-line

TOC and total nitrogen/total phosphorus analyzers provide real-time TOC

removal for drinking water treatment, process monitoring of BOD and

nitrogen / phosphorus removal in wastewater treatment, or continuous

monitoring of organic carbon, nitrogen, and phosphorus loading in

ambient water.

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TOCTotal Organic Carbon On-line TOC On-line Total

Nitrogen/Phosphorus

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Total Organic Carbon AnalyzerTotal organic carbon (TOC) analyzers measure the total amount of organic matter contained in water. They are used for a wide range of applications, from environmental analysis, water treatment management, and various processing control applications, to evaluating the effectiveness of cleaning or the amount of organic eluting material in water. TOC analyzers are available as either laboratory models or on-line analysis models. Laboratory TOC analyzers offer a wide assortment of options for analyzing everything from ultra-pure water to contaminated water and solid samples to gas samples. Shimadzu offers models based either on the 680°C combustion catalytic oxidation method, developed by Shimadzu and subsequently spread around the world, or the wet oxidation method. With an ultra-wide measurement range (4 μg/L to 30,000 mg/L), patented 680°C Combustion Catalytic Oxidation/NDIR detection method, and powerful options/accessories, the TOC-L Series meets the TOC testing requirements in wide range of applications.

Products

• Catalytic combustion oxidation TOC analyzer • Wet chemical oxidation TOC analyzer • Total nitrogen unit for TOC• Solid sample combustion unit for TOC• On-line TOC analyzer• On-line total nitrogen/phosphorus analyzer

TOC-L SeriesApplicationsEnvironmental WaterProcess WaterUltra-Pure WaterCleaning ValidationPharmaceutical Water Management

On-Line TOC / TN AnalyzerOn-line TOC analyzers are used for a wide variety of applications, from managing the raw water for wastewater treatment, or managing the discharge or effluent water after it has been treated, to monitoring the organic impurities in public water supplies, cooling water, condensate water, or rinse water. The 4200/4110 Series Shimadzu On-Line Water Quality Analyzers, with their proven combustion technology, lead the way in on-line water quality analysis technology. The TOC-4200 features the proven, industry-standard 680°C Combustion Catalytic Oxidation Method and a number of cost-reducing features to support sensitive, efficient TOC analyses. Features include multi-functional sample injector, high-salt sample combustion tube kit, and an on-board air purifier.

Products

• TOC-4200 (On-line TOC Analyzer)• TOCN-4110 (On-line TOC/TN Analyzer)• TN-4110 (On-line TN Analyzer)

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TOC-4200ApplicationsManagement of Influent and Effluent WaterMonitoring of Boiler and Condensate WaterManagement of Various Plant WaterWater Quality Monitoring for Regulatory Reporting

Testing Instruments for Physical PropertiesShimadzu began production of its first material testing machine in 1917,

and has since continued to provide testing machines that are vital to

product development. Instruments include our Autograph high-precision

universal testing machines, Servopulser fatigue testing machines, hardness

testers and particle size analyzers. These products have undergone many

improvements and are now widely accepted as being equipped with

superior technology. Essentially, testing machines have been in existence

since the onset of manufacturing to assure the quality of production

metrics. Our efforts to satisfy the rigorous demands of customers

over the past 90+ years have earned us the reputation as the world’s

top manufacturer of testing machines. Shimadzu remains committed

to challenging ourselves to innovate and develop new evaluation

technologies to satisfy the increasing demands for safety and reliability.

38Particle SizeAnalyzers

Universal Testers Hardness TestersFatigue and Endurance Testers

ThermalAnalyzers

High-SpeedVideo Camera

Universal TesterTests to evaluate the strength of objects are conducted across a wide range of scales – from fine particles and surface-mounted components in the nano-range to large steel and concrete specimens. The forces applied to the test specimens by the tester also cover a wide range from 2 mN to 2000 kN (or more). Various types of strength tests are conducted, including tensile, compression, bending, crack, peeling, creep, and stress relaxation testing. The Shimadzu Universal Tester lineup features a range of powerful tools for every field of application that meets all customer requirements.

Products

• UH-X/FX Series (Hydraulic universal tester)• AG-X plus Series (“Autograph” precision tester)• AGS-X Series (Standard universal tester)• EZ-X Series (Tabletop precision tester)

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Autograph AG-X plusApplicationsSteel & MetalsPlastics & RubberCompositesTextiles

40

Fatigue and EnduranceTestersThe evaluation of strength, which relates to safety and durability, will affect a product’s life. It has become increasingly important in areas such as product development, quality control and failure analysis. The Servopulser Series of high-performance, high-accuracy strength testing machines can accommodate this diverse range of requirements. The comprehensive lineup allows configuration of the optimal system for each user’s requirements.

The EMT Series Servopulser is a dynamic strength testing machine that operates exclusively on electric power. With closed loop (servo) control, it allows stable loading over a wide range of test forces and displacements (strain) for dynamic or static testing.

Products

• EMT Series• Microservo (Magnetic micro fatigue tester MMT series)

EMT SeriesApplicationsResinRubbersMetals / Electronic PartsComposites

Hardness and Surface Evaluation TestersThe micro hardness tester is an instrument that is indispensable to metallographic research, product quality control, and the research and development of new materials. For this type of work, it is important to be able to measure the hardness of small parts and metallic structures used in precision equipment, processed surface layers, metal plating layers, etc. This type of measurement must be performed on a limited small area with virtually no damage to the area being measured, and must yield extremely reliable results.

Winner of an IBO 2013 Industrial Design Award, the operator-friendly HMV-G Series of Micro Vickers hardness testers features a built-in CCD camera for automatic length measurement, an automatic lens switching function, and a sample shape recognition function. In addition, the innovative G-frame design dramatically improves operability while permitting effective measurement of long and large test samples.

Products

• HMV-G Series (Micro Vickers hardness tester) • DUH Series (Dynamic ultra micro hardness tester) • MCT Series (Micro compression tester)

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HMV-G SeriesApplicationsSteel & MetalsHeat Treatment CeramicsElectrical & ElectronicsSolar Cells

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Powder & Particle Size AnalyzerFrom dense to superfine particles, Shimadzu has a high-performance particle size analyzer for a variety of applications. Laser diffraction particle size analyzers measure particle size distribution, a property which determines the behavior and characteristics of powders. For instance, in pharmaceuticals, particle size can influence the drug’s effectiveness or side effects. In the case of foods, particle size and the distribution can be a major factor in determining “smoothness to the teeth” and “texture”. The SALD-2300 is able to analyze wet or dry samples across a wide particle concentration range of 0.1 ppm to 20% and provides continuous measurement in real time, at minimum one-second intervals, for instantaneous analysis. In addition, it enables the measurement of high-concentration samples without dilution, preventing dispersion or agglomeration.

Products

• IG-1000 Plus (Single Nano Particle Size Analyzer, 0.5 nm to 200 nm)• SALD-201/301V (Laser Diffraction Particle Size Analyzer, 0.1 µm to 350 µm)• SALD-2300 (Laser Diffraction Particle Size Analyzer, 17 nm to 2500 µm)• SALD-7500nano (Laser Diffraction Particle Size Analyzer, 10 nm to 300 µm)

SALD-2300ApplicationsPharmaceuticalsOrganic/Inorganic ChemistryMetalsPolymers

Thermal AnalyzerThermal analyzers measure the temperature dependence of the sample substance’s physical properties by varying the temperature of samples. Shimadzu’s product line includes DSC models, which measure the transition reaction in a sample when heated or cooled, TGA models, which measure changes in mass, and TMA models, which measure the deformation of substances when exposed to non-oscillating loads, such as compression, tension, bending, and torsion. Featuring an integrated balance assembly, the DTG-60 provides high sensitivity and excellent stability over a wide dynamic mass range.

Products

• NEW DSC-60 Plus (Differential Scanning Calorimeters)• DTG-60/60H (Simultaneous TG/DTA)• TMA-60/60H (Thermomechanical analyzers)• Automatic TA (Auto DSC & Auto TG/DTA)• TGA-50/50H, 51/51H (Thermogravimetric Analyzers)

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DSC-60 PlusApplicationsPolymersPharmaceuticalsPetroleum IndustryFood ProductsMetalsCeramics

NEW

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High-Speed Video CameraShimadzu’s High-Speed Video Camera, the HyperVision HPV-X, offers world-class ultra-high-speed video recording of up to ten million frames per second. Dedicated software allows recording to start immediately after performing a few simple settings. Recorded images can be saved in general image formats such as AVI or BMP. The HPV-X permits recording of ultra-high-speed phenomena not previously possible in a wide variety of fields that require high-speed image capture, such as materials failure, fluid dynamics and combustion.

The HPV-2, with a recording speed of up to 1 million frames per second, allows multi-camera synchronized recording (up to 4 cameras), enabling the analysis of a phenomenon in more detail.

Products

• HPV-X (10,000,000 fps high-speed video camera)• HPV-2 (1,000,000 fps high-speed video camera)

HyperVision HPV-XApplicationsHigh-Speed ObjectsFluid DynamicsElectric DischargeHigh-Speed Phenomena at Micro-Scales

UniBloc Family of BalancesAUW-D Series Dual-range Semi-micro BalancesAUW-D dual-range semi-micro balances are the first five-decimal balances with the advantages of UniBloc one-piece force cell technology.

AUW/AUX/AUY/ATX/ATY Series Analytical BalancesAUW/AUX/AUY models are the newest single-range analytical balances engineered with the UniBloc technology. This provides especially fast response and superb stability.

UW/UX/TX/TXB Series Top-Loading BalancesThese top-loading balances are engineered with the UniBloc mechanism, resulting in unrivaled response, stability and durability. Powerful features support any imaginable weighing application. The UW Series includes internal calibration and fully-automatic calibration functions.

BW-K/BX-K Series Precision Platform BalancesThe Shimadzu Precision Platform balances have been engineered with the innovative UniBloc mechanism since 1989. Powerful features support any imaginable weighing application. The BW-K Series includes internal calibration weight.

MOC63u/MOC-120H Electronic Moisture BalancesIn many fields, a moisture analyzer is a necessary tool for quality control requirements. With the MOC63u, you can easily obtain accurate data. Simply place material on the pan and shut the cover. The MOC63u will start to measure. The MOC63u adapts to various materials and increases your work efficiency.

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Product Index by Market Page Automotive Chemicals

Clinical/Toxicology/Forensics Electronics Environmental

Food & Beverages

Fuels & Energy

Life Science

Material Science Pharmaceutical

UHPLC/HPLC 7

LC-MS/MS 11

GC 14

GC-MS/MS 16

MALDI-TOF 19

Bio-focused Products 22

UV-Vis 27

FTIR 28

Fluorescence 29

AA 30

ICP 31

XRD 33

EDXRF 34

TOC 36

Materials Testers 39

Particle Size 42

Thermal 43

High-speed Cameras 44

Balances 45

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Product Index by Market Page Automotive Chemicals

Clinical/Toxicology/Forensics Electronics Environmental

Food & Beverages

Fuels & Energy

Life Science

Material Science Pharmaceutical

UHPLC/HPLC 7

LC-MS/MS 11

GC 14

GC-MS/MS 16

MALDI-TOF 19

Bio-focused Products 22

UV-Vis 27

FTIR 28

Fluorescence 29

AA 30

ICP 31

XRD 33

EDXRF 34

TOC 36

Materials Testers 39

Particle Size 42

Thermal 43

High-speed Cameras 44

Balances 45

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Company names, product/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation or its affiliates, whether or not they are used with trademark symbol “TM” or “®”.Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services. Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.

For Research Use Only. Not for use in diagnostic procedures. The contents of this publication are provided to you “as is” without warranty of any kind, and are subject to change without notice. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication.

© Shimadzu Corporation, 2015

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