alireza nourazarian,phd -...

CURRICULUM VITAE

Alireza Nourazarian,PhD

Assistant Professor, Clinical Biochemistry

Date of Birth: 26/07/1976

Department of Biochemistry and Clinical Laboratories

Faculty of Medicine, Tabriz University of Medical Sciences. Tabriz-Iran

Tel/Fax: +98 (0411) 3364666, Email: [email protected]

Educational Background:

Kerman University of Medical Sciences, Kerman, Iran

Philosophy Doctorate (PhD) in Clinical biochemistry (Feb 2009- Feb 2013)

Thesis: investigation the effect of combined EGFR and c-src Antisense

Oligodeoxynucleotides encapsulated with PAMAM denderimers in HT-29 human colon

cancer cell line.

Supervisors: Dr.Ahmad gholamhoseinian and Dr.yadollah Omidi

Advisor: Dr.safar farajnia

NOURAZARIAN, AR. Curriculum Vitae

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Tabriz University of Medical Sciences, Tabriz, Iran

Master science (M.Sc) in clinical biochemistry (Sep 2001-Dec 2003)

Thesis: Comparison of glucose tolerance in renal transplant recipients and

Hemodialysis patients.

Supervisors: Dr. Mohammad Rahbaninobar and Dr. Hassan Argani

Advisor: Dr. Mohammad Noori

Tabriz University of Medical Sciences, Tabriz, Iran

Bachelors (B.Sc) in Nutrition sciences (Sep 1996- Sep 2000)

Thesis: Evaluation the lipid profiles of heart patients hospitalized in shahid madany

hospital.

Supervisor: Dr.Aref Hoseini

CAREER:

Tabriz University of Medical Sciences

Assistant Professor, Clinical Biochemistry 2013 – Present

Under- and post-graduate levels

Research Interests:

• Neurobiochemistry

• Pathophysiology of neurodegenerative diseases uses neurochemical and molecular biology methodology.

• Biochemical markers for diagnostic, identification of pharmaceutical effects in neurodegenerative diseases.

• Molecular mechanisms involved in the development of acute and chronic neurodegenerative disease.


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Laboratory skills:

Primer design and gene data banks- Advanced molecular techniques- flowcytometery- Real

Time PCR- Western Blot- Cell Culture Techniques- Electrophoresis- Fluorescence Microscopy-

Enzyme Linked Immunosorbent Assay (ELISA)- sodium dodecyl sulphate polyacrylamide gel

electrophoresis (SDS-PAGE).

Research Experience:

● Studied on novel procedures in Antisense therapy.

● Investigated several signaling pathways related to tumor development and

Chemoresistance.

● Studied on Glucose tolorance mechanism in renal transplant recipients and

Hemodialysis patients.

●studied on serum proteomes during pathological stages of hepatocarcinogenesis.

● Studying the structure and function of ribozymes and riboswitches.

●studies about Cell therapy for diabetes patients.

Short Courses & Workshops

2013 Interpretation of hormonal and thyroid hormone tests workshop, the 6th international

and 11th national congress on Quality improvement in clinical laboratory.

2013 Two-day seminar on ethics and professional commitment in teaching and medical

research, Medical Education Development Center, Tabriz University of medical sciences.

Teaching history:

Under- and post-graduate levels

Proteins and nucleic acids biochemistry

lipids and carbohydrate biochemistry

General Biochemistry І

General Biochemistry ІІ


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Medical Biochemistry І (Theoretical & practical)

Medical Biochemistry ІІ (Theoretical & practical

Biochemistry of Hormones (Theoretical& practical)

Quality Control in Clinical Laboratories

Principles of Biochemistry

Applied Biochemistry

Metabolism disorders

Biochemistry and Molecular Diagnosis

Enzymology

Presentation:

• Ali Reza Nourazarian, Seyed Manuchehr Nourazarian,Majid Tozihi (2014). Assessment the

expression and significance of CA15-3،CA27.29،CEA ،PAI-1 and uPA tumor markers before

and after radical surgery in patients with breast cancer, the 7th international and 12th national

congress on Quality improvement in clinical laboratory, Tehran, Iran.

• Ali Reza Nourazarian, Seyed Manuchehr Nourazarian,Arsalan Pourseif (2014). Investigation

the effect of lipid peroxidation and lipid profiles on antioxidant status in patients with ovarian

cancer, the 7th international and 12th national congress on Quality improvement in clinical

laboratory, Tehran, Iran.

• Seyed Manuchehr Nourazarian, Ali Reza Nourazarian , Majid Tozihi , Behrooz Pourasgari

(2014). Comparison of Human epididymis protein 4 (HE4) and CA125 variations in patients with

ovarian cancer, the 7th international and 12th national congress on Quality improvement in

clinical laboratory, Tehran, Iran.

• seyed Manuchehr Nourazarian,Rasoual Estakhri,Majid tozihi, Alireza Nourazarian,Fatemeh

soghra hamzavi (2013). Correlation between interleukin -6 and high sensitive c-reactive protein

in pathogenesis of diabetic nephropathy, The 6th international and 11th national congress on

Quality improvement in clinical laboratory, Tehran, Iran.

● Manuchehr Nourazarian, Rasoul estakhri, Alireza Nourazarian ,Homayun Dolatkhah(2012).


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The role of lactobacillus reuteri in reducing renal fibrosis in streptozotocin induced diabetic rats,

The 5th international and 10th national congress on Quality improvement in clinical laboratory,

Tehran, Iran.

● Alireza Nourazarian, Manuchehr Nourazarian, jafar maleki (2011). Biological differences and

changes in the reference values of thyroid hormones in healthy subjects in Tabriz. The 4th

international and 9th national congress on Quality improvement in clinical laboratory, Tehran,

Iran.

● Cell therapy in diabetes patients (2011), department of medical biochemistry Round

Presentation, Kerman University of medical sciences.kerman, Iran.

● Biochemical mechanisms of toxicity. Kerman university of medical sciences Lecture and

Research day,Kerman,Iran (2011).

●Serum proteomes during pathological stages of hepatocarcinogenesis (2010) department of

medical biochemistry round presentation, kerman university of medical sciences.kerman,Iran.

● Structure and function of ribozymes and riboswitches Kerman university of medical sciences

Lecture and Research day,Kerman,Iran (2009).

● Reza razzaghi, Reza mahdavi, Hasan argani, Alireza nourazarian ,Mohamad

narimani(2008). Effects of zinc supplementation on energy and macronutrient intake of patients

with chronic renal failure undergoing to hemodialysis. 6ThInternational Nutrition and dietetics

congress, Antalya, Turkey.

● Manuchehr Nourazarian,Behrooz pourasgari,Ardavan ghazanchai,Alireza nourazarian(2007)

Increased Serum Cystatin C in patients with liver disease. The 1th international and 6th national

Congress on Quality improvement in clinical laboratory, Tehran, Iran.

● Manuchehr Nourazarian,Homayoon dolatkhah, Ardavan ghazanchai, Alireza

nourazarian(2006). Common errors in clinical laboratories in Tabriz Imam Khomeini Hospital.

5th national Congress on Quality improvement in clinical laboratory, Tehran, Iran (2006).

● Rasoul Estakhri, Manuchehr Nourazarian, Homayoon dolatkhah, Behrooz pourasgari, Alireza

nourazarian.(2006) The relationship between low 25 - hydroxyvitamin D and prostate cancer.9th

congress of nutrition.Tabriz,Iran.


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● Reza Razaghi,Mohamad pouraghaibagmishe, Alireza nourazarian(2006)

The effect of regular aerobic activity and low-fat diet of plasma lipid profile in patients with

dyslipidemia or obesity. 9th congress of nutrition.Tabriz,Iran.

● Reza Razaghi, Alireza nourazarian, Homayoon dolatkhah, Manuchehr

Nourazarian,Mohamad Rahbaninoubar(2005) The effect of diet on plasma homocystein,

vitamine B12 and folic acid of the patients using anti hyper cholesterolemic and anti

hypertension. 8th congress of Biochemistry and 1th International Congress of Biochemistry and

Molecular Biology.Tehran.Iran.

● Alireza nourazarian, Mohamad Rahbaninoubar, Manuchehr Nourazarian,Amir Bahrami

bahrami(2003) Relationship between serum cholesterol levels and homo cysteine with oxidative

stress in hyper and hypo thyroidism. 8th congress of nutrition.Tabriz,Iran

● Reza razzaghi, Ali reza nourazarian, Reza mahdavi, Manouchehr nourazarian (2003)

Investigation of folic acid and Vitamin B12 serum levels in choronic renal failure under

haemodialysis in Tabriz Imam Khomeini hospital, Iran.18th

IMSSC congress ,Istanbul, Turkey.

● Reza razzaghi, Ali reza nourazarian ,Mohamad rahbani nobar ,Manouchehr

nourazarian.(2003) Hyper calciuria, hyper phosphaturia and growth retardation in children with

diabetes mellitus referred to imam Khomeini hospital Tabriz , Iran. 4th International Nutrition and

Dietetics congress. Antalya, Turkey.

Published papers:

1- Nourazarian AR, kangari P, Salmaninejad A. (2014). The Role of oxidative stress in the

Development and progression of breast cancer. Accepted

2-Jafari Vayghan H, Saleh Ghadimi S, Nourazarian AR (corresponding author). (2014).

Preventive and Therapeutic Roles of Ginseng - Focus on Colon Cancer. Asian Pacific J Cancer

Prev 15(2): 585-588

3- Estakhri R, Ghahramanzade A, Vahedi A, Nourazarian AR.(2013). Serum Levels of CA15-3,

AFP, CA19-9 and CEA Tumor Markers in Cancer Care and Treatment of Patients with Impaired

Renal Function on Hemodialysis. Asian Pacific J Cancer Prev 14(3): 1597-9


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4- Gholamhoseinian Najar A, Pashaei-Asl R, Omidi Y, Farajnia S, Nourazarian AR

(corresponding author).(2013). EGFR Antisense Oligonucleotides Encapsulated with

Nanoparticles Decrease EGFR, MAPK1 and STAT5 Expression in a Human Colon Cancer Cell

Line. Asian Pacific J Cancer Prev 14(1): 495-498

5- Nourazarian AR, Najar AG, Farajnia S, Khosroushahi AY, Pashaei-Asl R, Omidi Y.(2012).

Combined EGFR and c-Src Antisense Oligodeoxy nucleotides Encapsulated with PAMAM

Denderimers Inhibit HT-29 Colon Cancer Cell Proliferation. Asian Pacific J Cancer Prev

13(9):4751-6.

6- Nourazarian AR, Pashaei-Asl R, Omidi Y, Najar AG. (2012). c-Src antisense complexed with

PAMAM denderimes decreases of c-Src expression and EGFR-dependent downstream genes

in the human HT-29 colon cancer cell line. Asian Pac J Cancer Prev ;13(5):2235-40.

7- Argani H, Nourazarian AR, Rahbaninobar M, Noori M, Khosroshahi HT.(2004). Comparison

of glucose tolerance in renal transplant recipients and hemodialysis patients. BMC Nephrol. Sep

8; 5:11.

Published books/chapters:

1- Nourazarian M, dolatkhah H,ghazanchai A,Nourazarian AR.(2008). Comprehensive Guide to

Quality Control in Clinical Laboratories. .Akhtar press .Tabriz,Iran

2- Nourazarian M.Nourazarian AR. (2007) An overview of Biochemistry superior notes.Akhtar

press .Tabriz,Iran

Ongoing books/chapters:

1- Cellular Neurochemistry and Neural Membranes

2- Real Time PCR methods and applications guide.

3- Intercellular Signaling.

4- Inherited and Neurodegenerative Diseases.


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Research Projects:

1- Investigation the effects of Combined EGFR and c-Src Antisense Oligodeoxy

nucleotides Encapsulated with PAMAM Denderimers on HT-29 Colon Cancer Cell

Proliferation.(2012)

2- Relationship between body mass index (BMI), hematological indices, serum lipids.

Among students of Azad University of Marand. (2006)

Professional Society Memberships:

1-Biochemical Society of the Islamic republic of Iran

2- Research Center for Pharmaceutical Nanotechnology (RCPN)

Tabriz University of medical sciences

3-Iranian cancer Association

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