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Adrenergic ReceptorBeta Receptor

Adrenergic receptors are a class of G protein-coupled receptors thatare targets of the catecholamines especially norepinephrine andepinephrine Many cells possess these receptors and the binding of acatecholamine to the receptor will generally stimulate thesympathetic nervous system The sympathetic nervous system isresponsible for the fight-or-flight response which includes wideningthe pupils of the eye mobilizing energy and diverting blood flowfrom non-essential organs to skeletal muscle There are two maingroups of adrenergic receptors α and β with several subtypes αreceptors have the subtypes α1 and α2 β receptors have thesubtypes β1 β2 and β3 All three are linked to Gs proteins which in

turn are linked to adenylate cyclase Agonist binding thus causes a rise in the intracellular concentration of the secondmessenger cAMP Downstream effectors of cAMP include cAMP-dependent protein kinase (PKA) which mediatessome of the intracellular events following hormone binding

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Adrenergic Receptor Inhibitors amp Modulators

Bioactivity (+)-Penbutolol is a β-adrenoceptor antagonist with an IC 50

of 074 μM (+)-Penbutolol is an optical isomer of[1]

l-penbutolol with Na channel-blocking action + [2]

Bioactivity (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptorand with antihypertensive and anti-platelet5-HT2 receptoraggregation activities

Bioactivity (R)-(-)-Phenylephrine is a selective agonistα -adrenoceptor1primarily used as a decongestant

Bioactivity (R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487 and 470 forα -adrenoceptor1 pK si

α α and α receptors respectively1D 1B 1A

Bioactivity (RS)-Butyryltimolol is the racemate of ButyryltimololButyryltimolol is the butyryl ester of Timolol Timolol is inthe non-selective blocker family of medicationβ

Bioactivity (S)-Timolol maleate is a potent non-selective β-adrenergicreceptor antagonist (Ki values are 197 and 20 nM for β1 andβ2 receptor subtypes respectively) IC50 Value 197 nM(Ki forβ1) 20 nM(Ki for β2) Target β-adrenergic receptor(S)-Timolol 50 bioavailability following oralhellip

Bioactivity (plusmn)-Befunolol is a blocking agentβ-adrenoceptor Bioactivity Bisoprolol is a selective type β1 adrenergic receptor blocker

Bioactivity 3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is acinnamic acid derivative that has antidiabetic activity3-Hydroxy-4-methoxycinnamic acid binds to and activatesα1-adrenergic receptors (IC =14 microM) to enhance secrethellip50

Bioactivity 5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptorwith weak blocking activityα1 adrenoceptor

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(+)-Penbutolol ((R)-Penbutolol (+)-Isopenbutolol) Cat No HY-116790A

(4E)-SUN9221 Cat No HY-U00367

(R)-(-)-Phenylephrine (Phenylephrine) Cat No HY-B0769

(R)-(-)-Phenylephrine hydrochloride (Phenylephrine hydrochloride) Cat No HY-B0471

(RS)-Butyryltimolol Cat No HY-102032A

(S)-Timolol Maleate (L-714465 (Maleate) MK 950) Cat No HY-17380

(plusmn)-Befunolol Cat No HY-101752

(plusmn)-Bisoprolol (hemifumarate) (Bisoprolol hemifumarate salt) Cat No HY-B0076

3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) Cat No HY-N0761

5-HT2 antagonist 1 Cat No HY-U00365

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100 mg

Purity 990Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9951Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg 1 g

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Purity 9981Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 980Clinical Data LaunchedSize 100 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in Water

100 mg 5 g 10 g

Bioactivity Acebutolol Hydrochloride is a β-adrenergic receptorsantagonist used in the treatment of hypertension anginapectoris and cardiac arrhythmias

Bioactivity Adrenalone hydrochloride is a selective α1-adrenoceptoragonist used as a topical vasoconstrictor and hemostaticused to prolong the action of local anesthetics

Bioactivity AGN 192836 is a potent and selective agonistα2 adrenergicwith s of 87 41 and 66 nM for α2A α2B and α2CEC50receptor respectively

Bioactivity Alfuzosin is an α1 adrenergic receptor antagonist used totreat benign prostatic hyperplasia (BPH)

Bioactivity Alfuzosin hydrochloride is an α1 adrenergic receptorantagonist used to treat benign prostatic hyperplasia (BPH)

Bioactivity Amezinium metilsulfate has multiple mechanisms includingstimulation of alpha and beta-1 receptors and inhibitionofnoradrenaline and tyramine uptake

Bioactivity Amibegron hydrochloride is a selective β3-adrenoceptoragonist with an of 35 nM for in ratEC50 β-adrenoceptor

colon Amibegron hydrochloride has anxiolytic andantidepressant activity

Bioactivity Amitraz is a non-systemic acaricide and insecticide withalpha-adrenergic agonist activity interaction with octopaminereceptors of the central nervous system and inhibition ofmonoamine oxidases and prostaglandin synthesis

Bioactivity Ancarolol is a blocking agentbeta-adrenergic Bioactivity AR-08 is an agonist of used for theα2-adrenergic receptortreatment of attention deficit hyperactivety disorder (ADHD)

Acebutolol hydrochloride Cat No HY-17497A

Adrenalone hydrochloride Cat No HY-B1308

AGN 192836 Cat No HY-100300

Alfuzosin (SL 77499) Cat No HY-B0192

Alfuzosin hydrochloride (SL 77499-10) Cat No HY-B0192A

Amezinium methylsulfate (Amezinium metilsulfate Lu-1631) Cat No HY-A0275

Amibegron hydrochloride (SR 58611A) Cat No HY-103207

Amitraz (BTS-27419) Cat No HY-B1111

Ancarolol Cat No HY-100141

AR-08 Cat No HY-U00371

Purity 9894Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9695Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

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Purity 9957Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

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10 mg 50 mg

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10 mg 50 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Bioactivity Asenapine(Org 5222) inhibits adrenergic receptor (α1 α2Aα2B α2C) with Ki of 025-12 nM and also inhibits 5-HTreceptor (1A 1B 2A 2B 2C 5A 6 7) with Ki of 003-40nM IC50 Value 025-12 nM(Ki for adrenergic receptor)003-40 nM(Ki for 5-HT receptor) Target 5-HT Receptorhellip

Bioactivity Atenolol is a selective β1 receptor antagonist

Bioactivity Atipamezole is a synthetic with aα -adrenoceptor antagonist2 of 16 nMKi

Bioactivity Atipamezole hydrochloride is a synthetic α -adrenoceptor2 with a of 16 nMantagonist Ki

Bioactivity Bambuterol is a long acting beta-adrenoceptor agonist (LABA)used in the treatment of asthma it also is a prodrug ofterbutaline IC50 value Target beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people withseriously impaired liver function It can be used by peoplehellip

Bioactivity Bambuterol Hcl is a long acting beta-adrenoceptor agonist(LABA) used in the treatment of asthma it also is a prodrugof terbutaline IC50 value Target beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people withseriously impaired liver function It can be used by peoplehellip

Bioactivity Batefenterol (GSK961081TD-5959) is a novel muscarinicreceptor antagonist and agonist displaysβ -adrenoceptor2high affinity for hM2 hM3 muscarinic and hβ -adrenoceptor2with values of 14 13 and 37 nM respectivelyKi

Bioactivity Benzquinamide (P2647) is an antiemetic which can bind to the and (α2-AR) with K α2A α2B α2C adrenergic receptors i

values of 1365 691 and 545 nM respectively

Bioactivity Betaxolol is a selective beta1 adrenergic receptor blockerused in the treatment of hypertension and glaucoma

Bioactivity Betaxolol Hydrochloride is a selective beta1 adrenergicreceptor blocker used in the treatment of hypertension andglaucoma

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Asenapine (Org 5222) Cat No HY-10121

Atenolol ((RS)-Atenolol) Cat No HY-17498

Atipamezole (MPV 1248) Cat No HY-12380A

Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380

Bambuterol (KWD-2183 (plusmn)-Bambuterol) Cat No HY-17501

Bambuterol hydrochloride (KWD-2183 hydrochloride (plusmn)-Bambuterol hydrochloride) Cat No HY-17501A

Batefenterol (GSK961081 TD-5959) Cat No HY-12980

Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244

Betaxolol Cat No HY-B0381

Betaxolol hydrochloride (SL75212) Cat No HY-B0381A

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Purity 9993Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg

Purity 9951Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg

Purity 9990Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9965Clinical Data LaunchedSize 10mM x 1mL in DMSO

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Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Bioactivity Bometolol Hydrochloride is a blocking agentbeta-adrenergicused for the research of cardiovascular disease

Bioactivity Brimonidine (UK 14304) is a full α2-adrenergic receptor(α2-AR) agonist

Bioactivity Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist

Bioactivity Carbazochrome (sodium sulfonate) (AC-17) is an antihemorrhagicagent Target Others Carbazochrome is an antihemorrhagicagent that will cease blood flow by causing the aggregationand adhesion of platelets in the blood to form a plateletplug ceasing blood flow from an open wound It is hoped thathellip

Bioactivity Carteolol HCl is a non-selective beta blocker used to treatglaucoma Target Beta adrenergic Receptor Carteolol HCl is abeta-adrenergic antagonist used as an anti-arrhythmia agentan anti-angina agent an antihypertensive agent and anantiglaucoma agent Carteolol hydrochloride at 1 mmolLhellip

Bioactivity Carvedilol(BM14190) is a non-selective beta blockeralpha-1blocker with an IC50 of 38 μM for inhibition of LDLoxidation IC50 Value 38 μM ( inhibition of LDL oxidation)Target beta Adrenergic Receptor Carvedilol is anonselective-blocking agent and is used in the treatment ofhellip

Bioactivity Carvedilol (phosphate hemihydrate) (BM 14190 (phosphatehemihydrate)) is a non-selective beta blockeralpha-1 blockerwith an IC of 38 μM for inhibition of LDL oxidation50

Bioactivity Centanafadine is dual norepinephrine (NE)dopamine (DA)transporter inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NE DA andIC s50serotonin transporter respectively

Bioactivity Centanafadine (hydrochloride) is dual norepinephrine transporter inhibitor also inhibits(NE)dopamine (DA)

serotonin transporter with of 6 nM 38 nM and 83 nM forIC s50human NE DA and serotonin transporter respectively

Bioactivity Cicloprolol is a partial agonist β 1-adrenoceptor

Bometolol Hydrochloride Cat No HY-U00386

Brimonidine (UK 14304 AGN190342) Cat No HY-B0659

Brimonidine tartrate (UK 14304 (tartrate) AGN190342 (tartrate)) Cat No HY-B0659A

Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A

Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A

Carvedilol (BM 14190) Cat No HY-B0006

Carvedilol phosphate hemihydrate (BM 14190 (phosphate hemihydrate)) Cat No HY-B0006A

Centanafadine (EB-1020) Cat No HY-16736

Centanafadine hydrochloride (EB-1020 (hydrochloride)) Cat No HY-16736A

Cicloprolol hydrochloride Cat No HY-U00066

Purity 9978Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg

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Purity 980Clinical Data LaunchedSize 10mM x 1mL in Water

5 mg 10 mg 50 mg

Purity 9980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity gt98Clinical Data LaunchedSize 10 mg 50 mg 100 mg

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5 mg 10 mg 25 mg 50 mg 100 mg

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Purity 9989Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg

Purity 9995Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg

Bioactivity Clonidine hydrochloride is an agonist of andα2-adrenoceptorpotent antihypertensive agent

Bioactivity Clorprenaline hydrochloride is a β -adrenergic receptor2agonist

Bioactivity D2343 is a agonist and also is an β2-adrenoceptor α1- inhibitoradrenoceptor

Bioactivity Dapiprazole hydrochloride is a potent α-adrenergic blockingdrug which is used to reverse mydriasis after eyeexamination

Bioactivity Deriglidole is a peripheral antagonist with aadrenoceptorhigh affinity for α -adrenoceptors2

Bioactivity Detomidine produce dose-dependent sedative and analgesiceffects is a nonnarcotic synthetic α2-adrenergic agonist

Bioactivity Detomidine hydrochloride produce dose-dependent sedative andanalgesic effects is a nonnarcotic synthetic α2-adrenergicagonist

Bioactivity Dexmedetomidine Hydrochloride is an agonist of adrenergicalpha-2 receptor which is used in veterinary medicine for itsanalgesic and sedative properties Target Adrenergic alpha-2Receptor Dexmedetomidine acting at alpha(2A) adrenoceptorsmust be present during the encoding process to decreasehellip

Bioactivity DL-Epinephrine is the racemate of epinephrine L-Epinephrineis a hormone secreted by the medulla of the adrenal glandsL-Epinephrine is an and receptorα-adrenergic β-adrenergicagonist

Bioactivity Dobutamine Hcl(Dobutrex) is a sympathomimetic drug used in thetreatment of heart failure and cardiogenic shock Its primarymechanism is direct stimulation of β1 receptors of thesympathetic nervous system

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Clonidine hydrochloride Cat No HY-B0409A

Clorprenaline hydrochloride Cat No HY-B1347

D2343 Cat No HY-U00206

Dapiprazole hydrochloride Cat No HY-A0142A

Deriglidole (SL 86-0715) Cat No HY-101683

Detomidine Cat No HY-B0163

Detomidine hydrochloride Cat No HY-B0163A

Dexmedetomidine hydrochloride ((+)-Medetomidine

hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A

DL-Epinephrine ((plusmn)-Epinephrine (plusmn)-Adrenaline DL-Adrenali) Cat No HY-B0447

Dobutamine hydrochloride Cat No HY-15746

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Purity gt98Clinical Data No Development ReportedSize 1 mg

Purity 9903Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

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10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg

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Purity 9860Clinical Data LaunchedSize 10mM x 1mL in DMSO

500 mg 1 g

Purity gt98Clinical Data LaunchedSize 100 mg 500 mg

Purity gt98Clinical Data LaunchedSize 1 mg

Bioactivity Dopexamine hydrochloride is a β2 adrenergic receptoragonist

Bioactivity Doxazosin(UK 33274) is a quinazoline-derivative thatselectively antagonizes postsynaptic α1-adrenergic receptors

Bioactivity Doxazosin mesylate(UK 33274) is a quinazoline-derivative thatselectively antagonizes postsynaptic α1-adrenergic receptorsTarget α1-adrenergic receptor Doxazosin (mesylate) is themesylate salt form of doxazosin which is a long-lastinginhibitor of α1-adrenoceptors that is widely used to treathellip

Bioactivity Ecastolol is a antagonist withbeta adrenergic receptorantianginal activities

Bioactivity Epanolol (Visacor ICI141292) is a potent β-adrenoceptorpartial agonist with a greater affinity for - thanβ1β2-adrenoceptors

Bioactivity Esmolol Hydrochloride is a beta adrenergic receptor blockerTarget Adrenergic receptor Esmolol Hydrochloride is thehydrochloride salt form of Esmolol a short and rapid-actingbeta adrenergic antagonist belonging to the class IIanti-arrhythmic drugs and devoid of intrinsic sympathomimetichellip

Bioactivity Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oxime function

Bioactivity Fenmetozole Tosylate is an antagonist of the actions ofethanol also antagonizes and acts asα2-adrenergic receptoran antidepressant drug

Bioactivity Fenspiride Hcl is an α adrenergic and H1 histamine receptorantagonist

Bioactivity Fiduxosin is a potent antagonist with ofα1-adrenoceptor Ki0160 nM 249 nM and 0920 nM for α1a- α1b- andα1d-adrenoceptors respectively

Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205

Doxazosin (UK 33274) Cat No HY-B0098

Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A

Ecastolol Cat No HY-101691

Epanolol (Visacor ICI141292) Cat No HY-U00183

Esmolol hydrochloride Cat No HY-B1392

Falintolol (Z)- Cat No HY-U00283

Fenmetozole Tosylate Cat No HY-U00402

Fenspiride Hydrochloride Cat No HY-A0027

Fiduxosin Cat No HY-U00399

Purity 9617Clinical Data LaunchedSize 100 mg 500 mg

Purity 980Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9850Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9993Clinical Data LaunchedSize 10mM x 1mL in DMSO

200 mg

Purity 950Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 25 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9996Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity gt98Clinical Data LaunchedSize 10 mg 50 mg

Purity 9888Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg 500 mg

Purity 9945Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg

Bioactivity Gramine (Donaxine) is a natural alkaloid isolated from giantreed acts as an active [2] adiponectin receptor (AdipoR)agonist with s of 32 and 42 microM for AdipoR2 and AdipoR1IC50

respectively Gramine is also a human and mohellip[1]

Bioactivity Guanabenz (Acetate) (BR-750) is an alpha-2 selectiveadrenergic agonist used as an antihypertensive agent

Bioactivity Guanfacine is a selective α2A receptor agonist Target α2AReceptor Guanfacine is a sympatholytic It is a selective α2Areceptor agonist These receptors are concentrated heavily inthe prefrontal cortex and the locus coeruleus with thepotential to improve attention resulting from interaction withhellip

Bioactivity Guanfacine Hcl an anti-hypertensive agent is a selectiveα2A-adrenoceptor agonist with Kd of 31 nM and displays 60-foldselectivity over α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is a sympatholytic Itis a selective α2A receptor agonist These receptors arehellip

Bioactivity Guanoxabenz is an agonistα2 adrenergic receptor Bioactivity HOKU-81 a new bronchodilator is one of the metabolites oftulobuterol

Bioactivity Hydrocortisone 17-butyrate is an adrenocortico hormone Bioactivity ICI 118551 (hydrochloride) is a highly selective β2 antagonist with s of 07 495 and 611adrenergic receptor Ki

nM for β2 β1 and β3 receptors respectively

Bioactivity Imoxiterol is a agonistβ-adrenergic Bioactivity Indacaterol(Onbrez Arcapta) is an ultra-long-actingβ-adrenoceptor agonist

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Gramine (Donaxine) Cat No HY-N0166

Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566

Guanfacine Cat No HY-17416A

Guanfacine hydrochloride Cat No HY-17416

Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123

HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291

Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983

ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951

Imoxiterol (RP 58802B) Cat No HY-101585

Indacaterol Cat No HY-14299

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Purity gt98Clinical Data LaunchedSize 1 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize

Purity 9839Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 990Clinical Data Phase 3Size 10mM x 1mL in DMSO

200 mg 1 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9992Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg

Bioactivity Indacaterol (QAB149) maleate is an ultra-long-actingβ-adrenoceptor agonist

Bioactivity Indanidine is an agonistalpha-adrenergic

Bioactivity Indoramin D5 is deuterium labeled Indoramin which is apiperidine antiadrenergic agent

Bioactivity Isoprenaline hydrochloride is a non-selective beta-adrenergic agonist with potent peripheral vasodilatorreceptor

bronchodilator and cardiac stimulating activities

Bioactivity Ivabradine D3 Hydrochloride is the deuterium labeledIvabradine hydrochloride Ivabradine hydrochloride is a new I inhibitor with IC of 29 μM and used as a pure heartf 50rate lowering agent

Bioactivity Ivabradine D6 hydrochloride is the deuterium labeledIvabradine hydrochloride Ivabradine hydrochloride is a new I inhibitor with IC of 29 μM and used as a pure heartf 50rate lowering agent

Bioactivity Ivabradine is an orally bioavailablehyperpolarization-activated cyclic nucleotide-gated ( )HCNchannel blocker

Bioactivity JP1302 dihydrochloride is a selective high affinityantagonist of the alpha2C-adrenoceptor (α -adrenoceptor)2Cwith a value (antagonist activity) of 16 nM and a K Kb i

(binding affinity) value of 28 nM [1] [2]

Bioactivity Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects in animals

Bioactivity Methyldopa is an alpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used as asympatholytic or antihypertensive Target alpha-adrenergicagonist Methyldopa is an alpha-adrenergic agonist (selectivefor α2-adrenergic receptors) psychoactive drug used as ahellip

Indacaterol maleate (QAB149) Cat No HY-14299A

Indanidine Cat No HY-101717

Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S

Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468

Ivabradine D3 Hydrochloride Cat No HY-B0162AS1

Ivabradine D6 hydrochloride Cat No HY-B0162AS

Ivabradine hydrochloride Cat No HY-B0162A

JP1302 dihydrochloride Cat No HY-103213

Ko-3290 Cat No HY-101721

L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225

Purity gt98Clinical Data LaunchedSize 10 mg 50 mg

Purity 9975Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg 200 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 990Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g

Purity 990Clinical Data LaunchedSize 1 g 5 g 25 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 250 mg 500 mg

Purity gt98Clinical Data LaunchedSize 1 g

Purity 9893Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g

Bioactivity L-(-)-α-Methyldopa hydrate is an alpha-adrenergic agonist(selective for α2-adrenergic receptors) psychoactive drug usedas a sympatholytic or antihypertensive Targetalpha-adrenergic agonist Methyldopa is an alpha-adrenergicagonist (selective for α2-adrenergic receptors) psychoactivehellip

Bioactivity L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergicagonist (selective for α2-adrenergic receptors) psychoactivedrug used as a sympatholytic or antihypertensive Targetalpha-adrenergic agonist Methyldopa is an alpha-adrenergicagonist (selective for α2-adrenergic receptors) psychoactivehellip

Bioactivity L-765314 is a potent and selective α1b adrenergic receptorantagonist with s of 54 nM and 20 nM for rat and human α1bKiadrenergic receptor respectively

Bioactivity L-771688 is a highly selective antagonistα1A-Adrenoceptorwith a of 043plusmn002 nMKi

Bioactivity L-Epinephrine is a hormone secreted by the medulla of theadrenal glands L-Epinephrine is an andα-adrenergic

receptor agonistβ-adrenergic

Bioactivity L-Epinephrine bitartrate is an and α-adrenergic β-adrenergicreceptor agonist L-Epinephrine is a hormone secreted by themedulla of the adrenal glands

Bioactivity L755507 is a potent selective agonist of with an β -AR3 IC50of 35 nM

Bioactivity Labetalol hydrochloride is a mixed alphabeta adrenergicantagonist that is used to treat high blood pressure

Bioactivity Latrepirdine dihydrochloride is a neuroactive compound withantagonist activity at histaminergic α-adrenergic andserotonergic receptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and ( )amyloid-β Aβsecretion

Bioactivity Levosalbutamol tartrate(levalbuterol) is the R-enantiomer ofthe short-acting β2-adrenergic receptor agonist salbutamol

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L-(-)-α-Methyldopa hydrate (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B

L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A

L-765314 Cat No HY-101385

L-771688 Cat No HY-U00237

L-Epinephrine ((-)-Epinephrine L-Adrenaline (-)-Adrenalin) Cat No HY-B0447B

L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate

salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A

L755507 Cat No HY-19334

Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108

Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537

Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457

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Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg 200 mg 500 mg

Purity gt98Clinical Data LaunchedSize 100 mg

Purity 9994Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9949Clinical Data No Development ReportedSize 10mM x 1mL in Water

10 mg 50 mg

Purity 9988Clinical Data LaunchedSize 5 mg 10 mg 50 mg

Purity 9774Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data LaunchedSize 50 mg

Purity 9908Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg

Purity 980Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 9811Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Bioactivity Levobetaxolol hydrochloride is a beta-adrenergic receptorinhibitor (beta blocker) used to lower the pressure in theeye in treating conditions such as glaucoma

Bioactivity Lidanserin is a drug which acts as a combined and5-HT2A antagonistα -adrenergic receptor1

Bioactivity Lofexidine is a selective agonist commonly usedα2-receptorto alleviate the physical symptoms of heroin and other typesof opioid withdrawal [1] [2]

Bioactivity Lofexidine (hydrochloride) is a selective α2-receptoragonist commonly used to alleviate the physical symptoms ofheroin and other types of opioid withdrawal [1] [2]

Bioactivity Lusaperidone (R107474) is an α2 antagonistadrenergic receptorwith s of 013 and 015 nM for α2A and α2C respectivelyKi

Bioactivity Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and 1750 nM forα2- and α1-adrenoceptors respectively)

Bioactivity Medetomidine Hydrochloride is an agonist of adrenergic alpha-2receptor which is used in veterinary medicine for itsanalgesic and sedative properties Target Adrenergic alpha-2Receptor Medetomidine acting at alpha(2A) adrenoceptors mustbe present during the encoding process to decrease discretehellip

Bioactivity Metipranolol is a non-selective β adrenergic receptorblocking agent

Bioactivity Metoprolol (Toprol) is a selective β1 receptor blocker used intreatment of several diseases of the cardiovascular systemespecially hypertension IC50 value Target β1 receptor

Bioactivity Metoprolol Succinate (Toprol XL) is a selective β1 receptorblocker used in treatment of several diseases of thecardiovascular system especially hypertension IC50 valueTarget β1 receptor

Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B

Lidanserin (ZK-33839) Cat No HY-101815

Lofexidine Cat No HY-B1052A

Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052

Lusaperidone (R107474) Cat No HY-U00117

Medetomidine Cat No HY-17034

Medetomidine hydrochloride (MPV785) Cat No HY-17034B

Metipranolol hydrochloride Cat No HY-16316

Metoprolol Cat No HY-17503

Metoprolol Succinate Cat No HY-17503A

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity gt98Clinical Data LaunchedSize 5 mg 10 mg 50 mg

Purity 9655Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g 10 g

Purity 9883Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 g 10 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

Purity 9996Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 1 g

Purity 9908Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data LaunchedSize 100 mg

Bioactivity Metoprolol is a cardioselective β1-adrenergic blocking agent Bioactivity MG 1 is an α1 antagonistadrenergic receptor

Bioactivity Midaglizole hydrochloride (DG5128) is a preferential antagonist Midaglizole hydrochlorideα2-adrenoceptor

(DG5128) exhibits 74 times higher affinity ( =628) towardpKiα2-adrenoceptor than α1-adrenoceptor

Bioactivity Mirabegron is a selective agonist withβ -adrenoceptor3 of 224 nMEC50

Bioactivity Moxisylyte (hydrochloride) is (alpha 1-blocker) antagonist itcan vasodilates cerebral vessels without reducing bloodpressure It is also used locally in the eye to reverse themydriasis caused by phenylephrine and other sympathomimeticagents [1][2]

Bioactivity Nadolol D9 is the deuterium labeled Nadolol(SQ-11725) whichis a non-selective beta blocker

Bioactivity Naftopidil (Flivas) a selective α1-adrenergic receptorantagonist or alpha blocker is an antihypertensive drug

Bioactivity Naphazoline HCl is an ocular vasoconstrictor and imidazolinederivative sympathomimetic amine

Bioactivity Nebivolol selectively inhibits β1- adrenergic receptor withIC50 of 08 nM

Bioactivity Nebivolol hydrochloride selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM

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Metoprolol Tartrate Cat No HY-17503B

MG 1 Cat No HY-U00110

Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165

Mirabegron (YM178) Cat No HY-14773

Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435

Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S

Naftopidil (KT-611 BM-15275) Cat No HY-B0391

Naphazoline hydrochloride Cat No HY-B0446

Nebivolol (R 065824) Cat No HY-B0203

Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A

wwwMedChemExpresscom 13

Purity gt98Clinical Data Phase 3Size 5 mg 10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 250 mg 500 mg

Purity 990Clinical Data No Development ReportedSize 10mM x 1mL in Water

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data LaunchedSize 500 mg 1 g 5 g

Purity 9975Clinical Data LaunchedSize 10mM x 1mL in DMSO

500 mg 1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 500 mg

Purity 9906Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity 9971Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg

Bioactivity Nefazodone hydrochloride is an antidepressant drug Bioactivity Nicergoline is an ergot derivative used to treat seniledementia and other disorders with vascular origins TargetAlpha-1A adrenergic receptor Nicergoline acts by inhibitingthe postsynaptic alpha(1)-adrenoceptors on vascular smoothmuscle This inhibits the vasoconstrictor effect ofhellip

Bioactivity Norepinephrine (Levarterenol L-Noradrenaline) is a-selective agonist with of 537β1 adrenergic receptor EC50

μM

Bioactivity Norepinephrine bitartrate monohydrate (Levarterenol bitartratemonohydrate L-Noradrenaline bitartrate monohydrate) is a

-selective agonist with of 537β1 adrenergic receptor EC50μM

Bioactivity Norepinephrine hydrochloride (Levarterenol hydrochlorideL-Noradrenaline hydrochloride) is a -selective β1 adrenergic

agonist with of 537 μMreceptor EC50

Bioactivity NRA-0160 is a selective antagonistdopamine D4 receptorwith a value of 048 nM and with negligible affinity forKi

( gt10000 nM) (dopamine D2 receptor Ki D3 receptor

39 nM) rat ( 180 nM) and ratKi 5-HT2A receptor Ki

Bioactivity Octopamine Hydrochloride is an endogenous biogenic amine thatis closely related to norepinephrine and has effects on theadrenergic and dopaminergic systems

Bioactivity OPC-28326 is a selective peripheral vasodilator and anangatonist of with of 2040 285α2-adrenergic receptor Kiand 55nM for α2A- α2B- and α2C-adrenoceptors respectively

Bioactivity Pamatolol is a cardioselective antagonistbeta-adrenoceptorwithout sympathomimetic activity

Bioactivity Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3receptor agonist and serotonin 5-HT1A receptor agonist D2(pKi = 81) and D3 receptor (pKi = 86) partial agonist (IA =50 and 67 respectively) and 5-HT1A receptor (pKi = 85)full agonist (IA = 100) also binds to D4 (pKi = 78)hellip

Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396

Nicergoline Cat No HY-B0702

Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715

Norepinephrine bitartrate monohydrate (Levarterenol

(bitartrate monohydrate) hellip) Cat No HY-13715B

Norepinephrine hydrochloride (Levarterenol (hydrochloride)

L-Noradrenaline (hydrochloride)) Cat No HY-13715A

NRA-0160 Cat No HY-101641

Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A

OPC-28326 Cat No HY-101610

Pamatolol Cat No HY-U00019

Pardoprunox (SLV-308 DU-126891) Cat No HY-14958

Purity 9968Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9984Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg

Purity 9988Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg

Purity 9983Clinical Data LaunchedSize 10mM x 1mL in Water

100 mg 500 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

200 mg 500 mg 1 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 9990Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g

Purity 9962Clinical Data LaunchedSize 10mM x 1mL in Water

10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9889Clinical Data Phase 3Size 5 mg 10 mg 50 mg 100 mg

Bioactivity Pardoprunox hydrochloride is a novel partial dopamine D2 andD3 receptor agonist and serotonin 5-HT1A receptor agonist D2(pKi = 81) and D3 receptor (pKi = 86) partial agonist and5-HT1A receptor (pKi = 85) full agonist

Bioactivity Pargolol hydrochloride is a β adrenergic receptorantagonist

Bioactivity Penbutolol sulfate is able to bind to both beta-1 adrenergicreceptors and beta-2 adrenergic receptors (the two subtypes)thus making it a non-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of high bloodpressure

Bioactivity Perphenazine is a typical antipsychotic drug inhibits5-HT receptor Alpha-1A adrenergic receptor Dopamine2A

and receptor D2D3 D2L receptor Histamine H1 receptorwith values of 56 10 0765013 34 and 8 hellipKi

Bioactivity Perphenazine D8 Dihydrochloride is the deuterium labeledPerphenazine which is a typical antipsychotic drug(5-HTDopamine receptor ligand)

Bioactivity Phenoxybenzamine hydrochloride is a selective antagonist ofboth and that is commonly usedα-adrenoceptor calmodulinfor the treatment of hypertension specifically caused bypheochromocytoma

Bioactivity Phentolamine mesylate is a competitive reversible antagonist with an between 5 and 30 nMα-adrenoceptor IC50

Bioactivity Pimozide is a antagonist with s ofdopamine receptor Ki14 nM 25 nM and 588 nM for dopamine D2 D3 and D1receptors respectively and also has affinity at

with a of 39 nM Pimozide also inhibhellipα1-adrenoceptor Ki

Bioactivity Pindolol (LB-46) is a nonselective β-blocker with partialbeta-adrenergic receptor agonist activity also functions as a5-HT1A receptor weak partial agonist antagonist (Ki=33nM)

Bioactivity Piperoxan hydrochloride is an α adrenoceptor antagonist2

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Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A

Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658

Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154

Perphenazine Cat No HY-A0077

Perphenazine D8 Dihydrochloride Cat No HY-A0077AS

Phenoxybenzamine hydrochloride Cat No HY-B0431A

Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A

Pimozide (R6238) Cat No HY-12987

Pindolol (LB-46) Cat No HY-B0982

Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850

wwwMedChemExpresscom 15

Purity 9925Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9998Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9916Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9992Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg 1 g

Purity gt98Clinical Data No Development ReportedSize 10 mg

Purity 9973Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 200 mg 500 mg

Purity gt98Clinical Data LaunchedSize 10 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 9990Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg 500 mg

Bioactivity Piribedil is a ( ) agonistdopamine D receptor2 D R2which also displays antagonist property at hα -adrenoceptor1A( )hα -AR1A

Bioactivity Piribedil D8 is the deuterium labeled Piribedil which is anantiparkinsonian agent

Bioactivity Prazosin is an alpha-adrenergic blocker and is a sympatholyticdrug used to treat high blood pressure and anxiety PTSD andpanic disorder

Bioactivity Prazosin is an alpha-adrenergic blocker and is a sympatholyticdrug used to treat high blood pressure and anxiety PTSD andpanic disorder Target Adrenergic Receptor Prazosin is asympatholytic drug used to treat high blood pressure andanxiety PTSD andpanic disorder It is an alpha-adrenergichellip

Bioactivity Pronethalol is a non-selective beta-adrenergic blocking agentprotect against and to reverse Digitalis-induced ventriculararrhythmias Target beta-adrenergic receptor

Bioactivity Propranolol hydrochloride is a nonselective β-adrenergicreceptor ( ) antagonist with an of 12 nMβAR IC50

Bioactivity QF0301B is an antagonist and a low α2α1 adrenergic receptoradrenoceptor 5-HT2A and histamine H1 receptor blocker

Bioactivity Rauwolscine hydrochloride is a potent and specific α2 receptor antagonist with a of 12 nMadrenergic Ki

Bioactivity Rotigotine is a full agonist of adopamine receptorpartial agonist of the and an antagonist of5-HT1A receptorthe with s of 071nM 4-15nM andα2B-adrenergic receptor Ki83nM for the dopamine D3 receptor and D2 D5 D4 receptorsand dopamine D1 receptor

Bioactivity RS 17053 hydrochloride is a potent and selective α1A antagonist with a value of 91 in nativeadrenoceptor pKi

cell membrane and a value of 98 in functional assayspA2

Piribedil Cat No HY-12707

Piribedil D8 (ET-495 D8) Cat No HY-12707S

Prazosin Cat No HY-B0193

Prazosin hydrochloride Cat No HY-B0193A

Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238

Propranolol hydrochloride Cat No HY-B0573

QF0301B Cat No HY-101690

Rauwolscine hydrochloride (α-Yohimbine hydrochloride

Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A

Rotigotine (N-0437 N-0923) Cat No HY-75502

RS 17053 hydrochloride (RS-17053) Cat No HY-101336

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9977Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg 200 mg 500 mg 1 g

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9996Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 10 mg 50 mg 100 mg

Purity 9766Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg

Purity 9968Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in Water

100 mg 500 mg

Purity gt98Clinical Data LaunchedSize 10 mg 50 mg 100 mg

Bioactivity Salbutamol is a short-acting β2-adrenergic receptor agonistused for the relief of bronchospasm in conditions such asasthma and chronic obstructive pulmonary disease (COPD)

Bioactivity Salbutamol Hemisulfate is a short-acting β2 adrenergicreceptor agonist Target β2 Adrenergic Receptor Salbutamol isa short-acting selective beta2-adrenergic receptor agonistused in the treatment of asthma and COPD All the effects ofRS-salbutamol on guinea-pig skeletal muscles are due to thehellip

Bioactivity Salmeterol is a long-acting beta2-adrenergic receptor (beta2AR) agonist used clinically to treat asthma

Bioactivity Salmeterol xinafoate is a long-acting beta-2 adrenergicreceptor ( ) agonist with of 15 nM for WT β ARβ AR2 Ki 2and used for asthma treatment

Bioactivity Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in the treatment ofacute circulatory shock

Bioactivity Scopine Hcl salt is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in the treatment ofacute circulatory shock

Bioactivity Silodosin (Rapaflo KMD-3213) is an α1-adrenoceptor antagonistwith high uroselectivity In treatment of dysuria

Bioactivity Solabegron (GW 427353) is a selective β -adrenergic receptor3agonist stimulating cAMP accumulation in Chinese hamsterovary cells expressing the human β -AR with an value3 EC50

of 22 nM Solabegron (GW 427353) is being developed hellip[1]

Bioactivity Sotalol Hydrochloride is an adrenergic beta-antagonist that isused in the treatment of life-threatening arrhythmias TargetAdrenergic Receptor Sotalol is a non-selective competitiveβ-adrenergic receptor blocker that also exhibits Class IIIantiarrhythmic properties by its inhibition of potassiumhellip

Bioactivity Spirendolol is a antagonistβ adrenergic receptor

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Salbutamol (Albuterol AH-3365) Cat No HY-B1037

Salbutamol hemisulfate (Albuterol (hemisulfate) AH-3365 (hemisulfate)) Cat No HY-B0436

Salmeterol (GR33343X) Cat No HY-14302

Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453

Scopine (67-Epoxytropine) Cat No HY-B0459

Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A

Silodosin (KAD 3213 KMD 3213) Cat No HY-10122

Solabegron (GW 427353) Cat No HY-19436

Sotalol hydrochloride (MJ-1999) Cat No HY-B0437

Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817

wwwMedChemExpresscom 17

Purity 9990Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in Water

1 g 5 g

Purity 9985Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg

Purity gt98Clinical Data LaunchedSize 100 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 9999Clinical Data LaunchedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9983Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg 500 mg

Bioactivity Synephrine Hcl(Oxedrine) is an alkaloid synephrine producesmost of its biological effects by acting as an agonist atadrenergic receptors

Bioactivity Talipexole dihydrochloride (B-HT 920 dihydrochloride) is adopamine D2 receptor agonist α2-adrenoceptor agonist and5-HT3 receptor antagonist which displays antiParkinsonianactivity

Bioactivity TD-5471 hydrochloride is a potent and selective full agonistof the human β -adrenoceptor2

Bioactivity Tedatioxetine hydrobromide acts as a triple reuptake inhibitorand and 5-HT2A 5-HT2C 5-HT3 α -adrenergic receptor1Aantagonist

Bioactivity Teoprolol is a blockerβ-adrenergic receptor Bioactivity Terazosin is a selective alpha1-antagonist used for treatmentof symptoms of benign prostatic hyperplasia (BPH)

Bioactivity Terazosin Hydrochloride dihydrate is a selectivealpha1-antagonist used for treatment of symptoms of benignprostatic hyperplasia (BPH)

Bioactivity Terbutaline sulfate is a β2-adrenergic receptor agonist afast-acting bronchodilator and a tocolytic to delay prematurelabor

Bioactivity Tertatolol is a potent antagonist of andbeta-adrenoceptor with unique renal vasodilatatory effects5-HT receptor

Bioactivity Tetrahydrozoline (hydrochloride) is a α-adrenoceptor agonist

Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A

Talipexole dihydrochloride (B-HT 920 (dihydrochloride)) Cat No HY-A0008

TD-5471 hydrochloride Cat No HY-19942A

Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755

Teoprolol Cat No HY-U00016

Terazosin Cat No HY-B0371

Terazosin hydrochloride dihydrate Cat No HY-B0371A

Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802

Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356

Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg

Purity gt98Clinical Data LaunchedSize 100 mg 500 mg

Purity 9989Clinical Data No Development ReportedSize 50 mg

Purity 9982Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg 100 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 990Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 1 g 5 g

Purity 9948Clinical Data LaunchedSize 10mM x 1mL in Water

10 mg 50 mg 100 mg

Purity gt98Clinical Data LaunchedSize 10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Bioactivity Tiodazosin is a potent competitive postsynaptic alpha antagonistadrenergic receptor

Bioactivity Tizanidine is an α2-adrenergic receptor agonist and inhibitsneurotransmitter release from CNS noradrenergic neurons

Bioactivity Tizanidine hydrochloride is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNS noradrenergicneurons Target α2-adrenergic receptor Tizanidine is a drugthat is used as a muscle relaxant It is a centrally acting α2adrenergic agonist It is used to treat the spasms crampinghellip

Bioactivity Tolazoline(Imidaline) is a non-selective competitiveα-adrenergic receptor antagonist

Bioactivity Tolazoline (hydrochloride)(Imidaline (hydrochloride)) Hcl is anon-selective competitive α-adrenergic receptor antagonistIC50 value Target α-adrenoceptor antagonist Tolazoline canbe synthesized by the heterocyclation of the ethyl ester ofiminophenzylacetic acid with ethylene diamine which forms thehellip

Bioactivity Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor

Bioactivity Tulobuterol hydrochloride is a agonistβ2-adrenoceptor Bioactivity Urapidil is an antagonist and a α1 adrenoreceptor 5-HT1A agonistreceptor

Bioactivity Urapidil HCl is an α1-adrenoceptor antagonist and 5-HT1Areceptor agonist

Bioactivity Vanilpyruvic acid is a catecholamine metabolite and precursorto vanillactic acid

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Tiodazosin (BL-5111) Cat No HY-100255

Tizanidine Cat No HY-B0194

Tizanidine hydrochloride Cat No HY-B0194A

Tolazoline (Imidaline NSC35110) Cat No HY-A0066

Tolazoline hydrochloride (Imidaline (hydrochloride) NSC35110 (hydrochloride)) Cat No HY-A0066A

Tropodifene (Tropaphen) Cat No HY-U00313

Tulobuterol hydrochloride Cat No HY-W011733

Urapidil Cat No HY-B0716

Urapidil hydrochloride Cat No HY-B0354A

Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416

wwwMedChemExpresscom 19

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg 20 mg

Purity 9985Clinical Data Phase 4Size 10mM x 1mL in DMSO

1 g

Purity gt98Clinical Data Phase 4Size 1 g

Purity 9988Clinical Data LaunchedSize 10mM x 1mL in DMSO

1 g

Purity 9990Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize 100 mg 500 mg

Purity 9902Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9506Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9925Clinical Data No Development ReportedSize 10mM x 1mL in Water

5 mg 10 mg 25 mg

Bioactivity Vatinoxan hydrochloride (MK-467 hydrochlorideL-659066hydrochloride) is a peripheral α2 adrenergic receptorantagonist

Bioactivity Vilanterol is a long-acting (β -AR)β -adrenoceptor2 2agonist with 24 h activity The s for β -ARβ -ARpEC50 2 1and β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033respectively

Bioactivity Vilanterol trifenatate is a long-acting (ββ -adrenoceptor2-AR) agonist with inherent 24-hour activity The s2 pEC50

for β -AR β -AR and β -AR are 1037 698 and 7362 1 3respectively

Bioactivity Xylazine is α2 class of adrenergic receptor agonist

Bioactivity Xylazine Hydrochloride is α2 class of adrenergic receptoragonist

Bioactivity Xylometazoline Hydrochloride is an α-adrenoceptor agonistcommonly used as nasal decongestant

Bioactivity Yohimbine is a potent and relatively nonselective alpha2-adrenergic receptor (AR) antagonist with IC50 of 06 μMIC50 value 06 uM [1] Target alpha 2-adrenergic receptor invitro Yohimbine inhibits alpha2-receptor antagonist with Kiof 105 nM 119 nM and 119 nM for α2A α2B α2Chellip

Bioactivity Yohimbine hydrochloride is an alpha 2-adrenoreceptorantagonist blocking the pre- and postsynaptic alpha-2adrenoreceptors and causing an increased release ofnoradrenaline and dopamine IC50 value Target In vitro Invivo Yohimbine hydrochloride (02 mgkg ip) washellip

Bioactivity ZK-90055 hydrochloride is a agonistβ2 adrenergic receptor Bioactivity α1 adrenoceptor-MO-1 an S enantiomer has affinity at alpha 1 shows alphalytic activity and possessesadrenergic receptor

analgesic action more active than R enantiomer

Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A

Vilanterol (GW642444X GW642444) Cat No HY-14300

Vilanterol trifenatate (GW642444M) Cat No HY-14300A

Xylazine (BAY 1470) Cat No HY-B0443

Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A

Xylometazoline hydrochloride Cat No HY-B0475

Yohimbine Cat No HY-12715

Yohimbine Hydrochloride Cat No HY-N0127

ZK-90055 hydrochloride Cat No HY-U00293

α1 adrenoceptor-MO-1 Cat No HY-U00333

Purity gt98Clinical Data No Development ReportedSize 500 mg 250 mg

Bioactivity β -AR agonist 2 is a potent and selective 3 β -adrenergic3 ( ) agonist with an of 8 nMreceptor β -AR3 EC50

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β3-AR agonist 2 Cat No HY-U00391