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Vaccine for treatment of alcohol addiction Moscow – 2014

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Page 1: ADH-Pharm LLC

Vaccine for treatment ofalcohol addiction

Moscow – 2014

Page 2: ADH-Pharm LLC

Alarm!

Литры на человека

Every 5-th man and 6% of women all over the world die in result of alcohol consumption

Officially: in Russia there are more then 2,6 mln. patients with alcoholic

addiction. Real situation: 10 mln. people addicted of alcohol

Alcohol consumption per year

Liters/person

Page 3: ADH-Pharm LLC

Goal:Peptide vaccine for reduction of alcohol abuse in patients with

alcoholism

«New approaches are very actual in therapy of alcohol addiction. The idea of the vaccine is interesting and promising, such type of drug is

really required»

Maria VinnikovaMD, professor, Deputy Director on scientific and medical work «NSC

of Narcology», Ministry of Health of Russian Federation

Immunomodulator (polyoxidonium)

Peptide 11 a.a.Fragment of ethanol metabolism enzyme

Vaccine

Page 4: ADH-Pharm LLC

• Market of drugs for addiction treatment was valued at $8.8 billion in 2011

• Compound annual growth rate was 4,9% during period 2004–2011

• The market is projected to reach $12.7 billion and 5.3% CAGR during the 2011–2018 forecast period

(GBI Research, 2012).

Page 5: ADH-Pharm LLC

Most of patients with chronic alcohol addiction return to narcologist within first six months after treatment!

The main problems of antialcohol drugs – low efficiency and duration of action

Page 6: ADH-Pharm LLC
Page 7: ADH-Pharm LLC

Preclinical studies

Efficiency Specificity Safety

2014 20162015 2017

Russian patent

Clinical studiesSale of patent and license on vaccine

production to international

pharmacological company

Expected financing:

• Budgetary funds (FASIE «START»)• Extrabugetary funds (Venture funds)

Aim: 11 mln. rub.

Page 8: ADH-Pharm LLC

Project scientific adviser:Maksim Lovat’, PhD, senior researcher Lomonosov Moscow State University, Director of

SPF-category vivarium, “Institute of Mitoengeneering of Moscow State University” LLC

TEAM

Vsevolod Pavshintsev, CEO Nikita Mitkin, COO

Medical adviser:

Maria Vinnikova, MD, professor, Deputy Director on scientific and medical work «NSC of Narcology», Ministry of Health of Russian Federation

[email protected]

[email protected]

MSU Science Park. Project partner. Advise

in management and commercial activities