actives company overview_incos2016_draft040516
TRANSCRIPT
Actives International, L.L.CHigh Quality Active Ingredients …by Design
+1.201.236.2828www.ActivesInternational.com
6G Pearl CourtAllendale, NJ 07401
Our MissionDevelop and market highly refined active ingredients for personal care applications utilizing natural sources and advanced technologies.
Our Method• Explore• Select• Enhance• Deliver
Frombiomass
To finalingredient
ViaPure® Natural ExtractsViaPure® means …. high purity
…. low use levels…. cost efficient performance
High potency means ….
High purity means….…. low odor & color…. high potency
Natural Products Chemistry
Diverse sources: plant, marine, microbial, fungal
Lead to diverse chemicals & unique activities
Selection
FractionationBioassay
Discovery Process
Harvesting
Sourcing
Processing
Sustainable Production
Custom fermentation specialists
Sustainable Processing
Thorough Testing ProtocolsEnsure Safety & Efficacy
Safety In vitro Proof of Principle
In vivoClaim Substantiation
Highly-purified, biologically active ingredients from natural sources
Solutions for Skincare Concerns
Skincare Concern: Skintone Brightening
Skincare Solutions
ViaFerm® White ShiitakeViaPure® AndrographisViaPure® Licorice White
Skincare Solution Skincare Benefits
ViaFerm® White Shiitake
123
Picture of Shiitake
Skincare Concern: Skintone Brightening
Skincare Solution Skincare Benefits
ViaPure® Andrographis
123
Picture of Andrographis
Skincare Concern: Skintone Brightening
Skincare Solution Skincare Benefit
ViaPure® Licorice White
123
Picture of Glabridin
Skincare Concern: Skintone Brightening
Skincare Concern: Photoprotection
Skincare Solutions
ViaPure® Citrus ViaPure® Coleus
Skincare Solution Skincare Benefit
ViaPure® Citrus
123
Picture of Citrus
Skincare Concern: Photoprotection
Skincare Solution Skincare Benefit
ViaPure® Coleus
123
Picture of Coleus
Skincare Concern: Photoprotection
Skincare Concern: Sensitive Skin
Skincare Solutions
ViaPure® BoswelliaViaPure® HopsViaPure® LicoriceViaPure® Poria
Skincare Solution Skincare Benefit
ViaPure® Boswellia
123
Picture of Boswellia
Skincare Concern: Sensitive Skin
Skincare Solution Skincare Benefit
ViaPure® Hops
123
Picture of Hops
Skincare Concern: Sensitive Skin
Skincare Solution Skincare Benefit
ViaPure® Licorice
123
Picture of Licorice
Skincare Concern: Sensitive Skin
Skincare Solution Skincare Benefit
ViaPure® Poria
123
Picture of Poria
Skincare Concern: Sensitive Skin
Skincare Solution Skincare Benefit
ViaPure® Coleus123
Skincare Concern: Cellulite
Skincare Concern: Oily, Troubled Skin
Skincare Solution Skincare Benefit
ViaPure® Sabal123
Skincare Solution Skincare Benefit
ViaPure® Andrographis 1
ViaPure® Hops 1ViaPure® Poria 1
Skincare Concern: Eye Area
Skincare Concern: Desquamation
Skincare Solution Skincare Benefit
ViaPure® Rice123
Skincare Concern: Mature Skin
Skincare Solutions
ViaPure® Anogeissus ViaPure® Boswellia ViaPure® Citrus
Skincare Solution Skincare Benefit
ViaPure® Anogeissus
123
Picture of Anogeissus
Skincare Concern: Mature Skin
Skincare Solution Skincare Benefit
ViaPure® Boswellia
123
Picture of Boswellia
Skincare Concern: Mature Skin
Skincare Solution Skincare Benefit
ViaPure® Citrus
123
Picture of Citrus
Skincare Concern: Mature Skin
Skincare Concern: Healthy Skin Barrier
Skincare Solutions
ViaPure® Boswellia ViaPure® Coleus
Skincare Solution Skincare Benefit
ViaPure® Boswellia
123
Picture of Boswellia
Skincare Concern: Healthy Skin Barrier
Skincare Solution Skincare Benefit
ViaPure® Coleus
123
Picture of Coleus
Skincare Concern: Healthy Skin Barrier
Skincare Concern: EcoCert Ingredients
Skincare Solutions
ViaPure® Poria ViaPure® Sabal
A Global CompanyHeadquarters New Jersey USA
AgentsAustraliaCanadaChinaFranceGermanyItalyMalaysiaTaiwanUSA
Who We Are• Private company, Founded in 1998
• Headquarters: New Jersey, USA
• President & CEO: Jon Anderson, PhD
Headquarters: Allendale, NJ
# Employees: 14 Office area: 5,000 sq ftWarehouse: 13,000 sq ft
Award-winning Customer Service
13,000 sq ft Warehouse
Order assembly area
Skidded warehouse
Tote storage
Two Cold Storage Rooms
Large room with forklift access for skidded products
Small room convenient for small pack sizes
Efficient Material Handling,In-bound & Out-bound
Two shipping bays
Tradeshow Presence20x30 booth• SCC-NY
10x10 pop-up• SCC-CA• SCC-SW
Tabletop• SCC-FL• SCC-TW
Prompt Sampling Procedures
Most sample requests are shipped within 24 hours
Benefits of Our Approach
• High-purity extraction Improves color, odor, activity
Our Core Competencies
• Natural products chemistry
• Skin biology
• Safety and clinical efficacy studies
What We Do• Expertise in cosmetic raw material development and sales
• Proprietary brands and broad product line
• US sales force and sub-agencies around the US, Europe and Asia
• Custom product development for key customers
• Plants – High purity extracts• Marine – Phytoplankton / microalgae• Biofermentation• Custom fermentation
Land, Sea, and Lab
Sources for Actives
Same info as slides 7
&9?
• Plants
• Marine organisms
• Fungi
• Micro-organisms
Advanced Technology Aids Discovery ofActives from Nature
Same info as slides 7
&12?
• Identify activity / biomass of interest
• Conduct bioassay-directed fractionation
• Purify to isolate active, resulting in bench-top prototype
• Safety studies
• Clinical efficacy substantiation
In-house Development of High Purity Actives
Same idea as slide 4
From biomass
To active ingredient
Raw Material Development
Benefits of Our Approach• Controllable production by fermentation
Eliminates supply issuesProvides alternative engineering
Sustainable, low-carbon footprint
• Key Products– Marine micro algae
• Capabilities– Bioproduction– Down stream process
• New Developments
Microalgae Production
ViaPure® Natural Extracts
ViaPure® means …. high purity
High purity means….…. low odor & color…. high potency
Developing Long Term Relationships
Open cooperation among our partner companies• Manufacturing• Bioassays • Scientific exchange
Leading to • New opportunities that benefit both parties
Partners: Synergistic Expertise• Contipro Biotech
– R&D, biofermentations, manufacturing
• Corum– R&D, biopeptides, manufacturing
• US Biologics– Bio-fermentations, manufacturing
• Monteloeder– Sourcing, industrial scale-up
• Actives International– Natural products, discovery, bioassay,
prototype development
• Alchem & Olive Lifesciences– Sourcing, purifications, industrial scale-
up
• CLR– R&D, natural products, manufacturing,
marketing
“more like a PARTNER than a Distributor”
• We represent companies whose expertise complements our own core competencies
• Our partners have diverse manufacturing & research capabilities, which creates a set of unique synergies
• We frequently collaborate on the development or improvement of our partners’ products
Natural extracts Fermentationproducts
US agent US agent
MicroAlgae In DevelopmentFermentation
Co-owner
Sales andCustomerSupport
Researchand
Development
US BioLogics
US agent
BENEFIT
ViaFermWhite Shiitake Skin-tone lightening
Age spots
RECOMMENDED FOR
Exclusive US RepresentativeEstee Lauder Companies
Specialized in the development of biologically active ingredients fromnatural sources, many of which meet EcoCert and NaTrue standards
US Agent
Specialists in research, development and productionof hyaluronic acid, hyaluronic acid derivatives, and fermentation-derived bioactive molecules
US Agent
Exclusive US Representative
Northeast andSelected Multinational Companies
Develops, manufactures, and markets innovative active ingredients for the cosmetic and personal care industry
US Agent
Key Personnel
• Jon Anderson, PhD
• Young Anderson, PhD
• Thushara Diyabalanage, PhD
• Isabelle Balle
• Priya Malhotra, Michelle Rappoport
• Mary Davis
• Rose Chiusano
President; R&D
R&D Biology
R&D Chemistry
Operations
Sales
Marketing
Finance
SummaryOur MissionDevelop and market highly refined active ingredients from natural sources, utilizing the most advanced technologies
Our Method• Develop prototype raw materials in-house• Transfer technology to partners with manufacturing expertise• Develop sustainability in sourcing and production
Our FocusSkin treatment, hair care and personal care markets
Skincare Concern: Skintone Brightening
Skincare Solutions
ViaFerm® White ShiitakeViaPure® AndrographisViaPure® Licorice White
ViaPure® Product LineRECOMMENDED FOR
ViaPure Boswellia
Anti-inflammation Barrier repair
Sensitive skinFirmness & elasticity
BENEFIT
Picture of Boswellia
ViaPure® Product LineRECOMMENDED FOR
ViaPure Citrus
Anti-inflammation Photo-protection
FirmnessWrinkles
BENEFIT
Picture of Citrus
ViaPure® Product LineRECOMMENDED FOR
ViaPure Coleus
Keratinocyte differentiationPhoto-protectionPhoto-repairLipolysis
Barrier repairHealthy skinDaily use productsCellulite
BENEFIT
Picture of Coleus
ViaPure® Product LineRECOMMENDED FOR
ViaPureHops Anti-inflammation Under-eye products
BENEFIT
Picture of Hops
ViaPure® Product LineRECOMMENDED FOR
ViaPureLicorice Anti-inflammation
Eye productsSensitive skinWrinkles
BENEFIT
Picture of Licorice
ViaPure® Product LineRECOMMENDED FOR
ViaPureLicorice White
Multiple melanogenic pathway interactions
Skin-tone lightening
BENEFIT
Picture of Licorice Root
ViaPure® Product LineRECOMMENDED FOR
ViaPurePoria Anti-inflammation Eye products
Sensitive skin
BENEFIT
Picture of Poria
ViaPure® Product LineRECOMMENDED FOR
ViaPureRice Exfoliation
Cell renewal
BENEFIT
Picture of Rice
Skincare Concern: Cellulite
Skincare Solution
ViaPure® Coleus
Picture of Cellulite
Skincare Concern: Eye Area
Skincare Solutions
ViaPure® Andrographis ViaPure® Hops ViaPure® Poria