1987 nbde 1 asda (biochemistry & physiology )

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Test results Results for: Karol nbde Title: 1987 NBDE 1 ASDA (Biochemistry & Physiology ) Score: 54 out of 93 points Percentage: 58% Duration: 01:50:51 Date started: Sat 7th Apr 2012 6:29pm Date finished: Sat 7th Apr 2012 8:20pm Feedback: keep studying Key: A tick or cross will show next to chosen answers. Correctly answered Incorrectly answered Missed correct multiple choice option Question 1 of 93 The km value of an enzyme is numerically

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Page 1: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Test results

Results for: Karol nbde

Title:

1987 NBDE 1 ASDA (Biochemistry & Physiology )

Score:

54 out of 93 points

Percentage:

58%

Duration:

01:50:51

Date started:

Sat 7th Apr 2012 6:29pm

Date finished:

Sat 7th Apr 2012 8:20pm

Feedback:

keep studying

Key: A tick or cross will show next to chosen answers.

Correctly answered

Incorrectly answered

Missed correct multiple choice option

Question 1 of 93

The km value of an enzyme is numerically

equal to

Page 2: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: C)

You chose: C)

A)

1. half the maximum velocity expressed in moles/liter.

B)

velocity of a reaction divided by substrate concentration.

C)

substrate concentration in moles/liter necessary to achieve half the maximum velocity of a reaction.

D)

maximum velocity divided by half the substrate concentration in moles necessary to achieve maximum velocity.

Points: 1 out of 1

Question 2 of 93

The physiologically active form of vitamin D

produced in the kidney is

Correct answer: A)

You chose: A)

A)

1,25-dihydroxycholecalciferol.

B)

25-hydroxycholecalciferol.

C)

Page 3: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

7-dehydrocholesterol.

D)

cholecalciferol.

E)

ergosterol.

Points: 1 out of 1

Question 3 of 93

Which of the following is an example of

reduction?

Correct answer: E)

You chose: D)

A)

-CH - CH- + H2O ---> -CH2 - CHOH-

B)

R-COOH ---> R-COO- + H +

C)

-CH2 CH2 ---> -CH - CH- + H2

D)

Cu+ ---> Cu + 2 + e-

E)

Fe+3 + e ---> Fe + 2

Points: 0 out of 1

Question 4 of 93

The ketone body acetoacetate is synthesized inside mitochondria of hepatocytes by

Page 4: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: C)

You chose: C)

A)

carboxylation of pyruvic acid.

B)

transamination of-aspartic acid.

C)

cleavage of β-hydroxy-β-methylglutaryl CoA.

D)

oxidative decarboxylation of α-ketoglutarate.

E)

oxidation of L-β-hydroxybutyrate followed

by deacylation.

Points: 1 out of 1

Question 5 of 93

Acids found in the citric acid (Krebs) cycle are

Correct answer: E)

You chose: E)

A)

glutamic acid and succinic acid.

B)

glucuronic acid and aspartic acid.

Page 5: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

C)

oxaloacetic acid and aspartic acid.

D)

oxaloacetic acid and pyruvic acid.

E)

oxaloacetic acid and α-ketoglutaric acid.

Points: 1 out of 1

Question 6 of 93

The presence of glucose in the urine proves

that the patient has

Correct answer: C)

You chose: A)

A)

diabetes mellitus.

B)

negative nitrogen balance.

C)

exceeded his renal threshold for glucose.

D)

excessive damage to a glomerulus of the

kidney.

Points: 0 out of 1

Question 7 of 93

Carbonic anhydrase in kidney tubular cells is

Page 6: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

associated with reabsorption of

Correct answer: D)

You chose: D)

A)

urea.

B)

chloride.

C)

carbohydrate.

D)

bicarbonate ion.

Points: 1 out of 1

Question 8 of 93

An impulse can travel from one nerve to another in only one direction because the

Correct answer: A)

You chose: E)

A)

synapse limits the direction of travel.

B)

myelin sheath limits the direction of travel.

C)

myoneural junction limits the direction of travel.

Page 7: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

nerve fiber permits conduction in only one direction.

E)

cell-body must be stimulated before the nerve fiber will conduct.

Points: 0 out of 1

Question 9 of 93

The intracellular, "second" messenger for

many peptide and polypeptide hormones is

Correct answer: C)

You chose: C)

A)

AMP.

B)

ATP.

C)

cyclic AMP.

D)

adenylate cyclase.

E)

a cytoplasmic receptor.

Points: 1 out of 1

Question 10 of 93

Human parotid saliva is believed to be hyposmolar because

Page 8: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: D)

You chose: B)

A)

water is reabsorbed by excretory ducts of the gland.

B)

acinar cells transport water more readily than sodium ions.

C)

striated duct cells produce excess water and retain potassium.

D)

reabsorption of water by striated duct cells is less than reabsorption of" sodium.

Points: 0 out of 1

Question 11 of 93

Which of the following is the major

contributor to colloid osmotic pressure?

Correct answer: A)

You chose: A)

A)

Albumin

B)

Alpha globulin

C)

Beta globulin

D)

Page 9: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Gamma globulin

Points: 1 out of 1

Question 12 of 93

The dominant factor controlling absorption of iron from the gastrointestinal tract is

Correct answer: C)

You chose: D)

A)

excretion of iron in the urine.

B)

excretion of iron in the stools.

C)

saturation of mucosal cells with iron.

D)

concentration of the ferrous iron in bone

marrow, spleen and liver.

Points: 0 out of 1

Question 13 of 93

Spatial summation results from the

Correct answer: A)

You chose: A)

A)

convergence of several afferent impulses on the same postsynaptic nerve soma.

Page 10: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

B)

repetitive firing of discharges (from the same presynaptic terminal), eventually producing an action potential.

C)

exhaustion of the stores of transmitter substance at the synapse.

D)

elaboration of some inhibitory substance, such as y-aminobutyric acid, at the synapse.

Points: 1 out of 1

Question 14 of 93

Two atoms are considered isotopic if

Correct answer: B)

You chose: B)

A)

their nuclei contain the same number of

neutrons.

B)

their atomic numbers are the same, but

their mass numbers differ.

C)

their mass numbers are the same, but

their atomic numbers differ.

D)

one is a beta emitter, and the other an

alpha emitter.

Page 11: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Points: 1 out of 1

Question 15 of 93

The distribution of carbonate within dental

enamel follows the same surface to

dentinoenamel junction patterns as which of

the following?

Correct answer: E)

You chose: E)

A)

Lead

B)

Calcium

C)

Fluoride

D)

Strontium

E)

None of the above

Points: 1 out of 1

Question 16 of 93

A deficiency of vitamin A in a developing

tooth most likely affects the

Correct answer: B)

Page 12: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

You chose: B)

A)

pulp.

B)

enamel.

C)

dentin.

D)

cementum.

Points: 1 out of 1

Question 17 of 93

Visual purple, rhodopsin, is usually formed in the

Correct answer: C)

You chose: C)

A)

lens.

B)

liver.

C)

retina.

D)

adrenals.

E)

Page 13: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

vitreous humor.

Points: 1 out of 1

Question 18 of 93

Aldosterone is normally associated with

partial regulation of which of the following

processes?

Correct answer: A)

You chose: A)

A)

Sodium balance

B)

Gluconeogenesis

C)

Lipid digestion

D)

Protein degradation

E)

Carbohydrate metabolism

Points: 1 out of 1

Question 19 of 93

The normal delay in sexual development until puberty is attributed to

Correct answer: D)

You chose: D)

Page 14: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

lack of effect of sex hormones on somatic tissue.

B)

failure of the gonads to respond to gonadotrophins.

C)

inability of the hypophysis to synthesize gonadotrophins.

D)

lack of hypothalamic stimulation of gonadotrophin release.

E)

inability of the hypophysis to respond to hypothalamic releasing hormones.

Points: 1 out of 1

Question 20 of 93

Neutral fats contain mixtures of one or more

fatty acids esterified with

Correct answer: B)

You chose: B)

A)

sterol.

B)

glycerol.

C)

lecithin.

D)

Page 15: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

sphingosine.

E)

alcohols of high molecular weight.

Points: 1 out of 1

Question 21 of 93

At rest, the potential difference across the

membrane of which of the following is

greatest?

Correct answer: C)

You chose: B)

A)

Odontoblast

B)

Sinoatrial node

C)

Skeletal muscle

D)

Visceral smooth muscle

Points: 0 out of 1

Question 22 of 93

Antidiuretic hormone acts to

Correct answer: D)

You chose: C)

Page 16: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

decrease renal filtration fraction.

B)

increase storage capacity of the bladder.

C)

decrease permeability of distoconvoluted

tubules and/or collecting ducts to water.

D)

increase permeability of distoconvoluted

tubules and/or collecting ducts to water.

Points: 0 out of 1

Question 23 of 93

The rapid movement of a substance across a biologic membrane against a concentration gradient requires

Correct answer: B)

You chose: E)

A)

that the substance be negatively charged.

B)

participation of an energy-requiring active transport system.

C)

that the substance be readily soluble in the lipid barrier of the membrane.

D)

Page 17: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

that the substance be carried across the membrane by rapid influx of the solvent.

E)

facilitated diffusion of the substance aided by some binding system in the membrane.

Points: 0 out of 1

Question 24 of 93

With glutamic acid as an ammo group donor,

alanine can be synthesized directly from

which of the following acids?

Correct answer: B)

You chose: C)

A)

Lactic acid

B)

Pyruvic acid

C)

Glutaric acid

D)

α-ketoglutaric acid

E)

3-phosphoglyceric acid

Points: 0 out of 1

Question 25 of 93

Neutralization of acids by saliva results

mainly from which of the following salivary

Page 18: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

contents?

Correct answer: D)

You chose: D)

A)

Mucin

B)

Ammonia

C)

Carbonate

D)

Bicarbonate

E)

Amino acids

Points: 1 out of 1

Question 26 of 93

Compared with hemoglobin A, the

substitution of a valine for a glutamic acid

residue in hemoglobin S results from

Correct answer: A)

You chose: A)

A)

a genetic mutation.

Page 19: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

B)

irradiation of hemoglobin A.

C)

proteolytic action in the liver.

D)

exposure to low oxygen tension.

Points: 1 out of 1

Question 27 of 93

Where is norepinephrine stored?

Correct answer: B)

You chose: A)

A)

At preganglionic sympathetic nerve endings

B)

At postganglionic sympathetic nerve endings

C)

At preganglionic parasympathetic nerve endings

D)

At postganglionic parasympathetic nerve endings

Points: 0 out of 1

Question 28 of 93

The most abundant form of iron in human

blood plasma is found

Page 20: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: D)

You chose: C)

A)

as free Fe++

B)

as free Fe+++

C)

as ferritin.

D)

associated with transferrin.

E)

associated with ceruloplasmin.

Points: 0 out of 1

Question 29 of 93

The main control over body temperature,

located in a portion of the central nervous

system, is the

Correct answer: C)

You chose: C)

A)

pons.

B)

cerebellum.

Page 21: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

C)

hypothalamus.

D)

medulla oblongata.

Points: 1 out of 1

Question 30 of 93

The second heart sound is related to

Correct answer: E)

You chose: D)

A)

excitation of atria.

B)

opening of AV valves.

C)

closure of AV valves.

D)

opening of aortic valves.

E)

closure of aortic valves.

Points: 0 out of 1

Question 31 of 93

In males, growth and development of

secondary sex organs are under direct control

of

Page 22: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: D)

You chose: D)

A)

FSH and LH.

B)

aldosterone.

C)

progesterone.

D)

testosterone.

Points: 1 out of 1

Question 32 of 93

The relative refractory period of a nerve

corresponds to

Correct answer: C)

You chose: A)

A)

sodium permeability changes.

B)

decreased potassium permeability.

C)

increased potassium permeability.

Page 23: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

threshold potential that is farther from zero.

Points: 0 out of 1

Question 33 of 93

The major center in the brain for autonomic

nervous system regulation is the

Correct answer: A)

You chose: A)

A)

hypothalamus.

B)

pituitary.

C)

cerebral cortex.

D)

vestibular nuclei.

E)

floor of the fourth ventricle.

Points: 1 out of 1

Question 34 of 93

Some sense organs, when stimulated continuously by a constant stimulus, may gradually lose their ability to continue to respond. this phenomenon is known as

Correct answer: C)

Page 24: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

You chose: C)

A)

occlusion.

B)

summation.

C)

adaptation.

D)

facilitation.

E)

sensory deprivation.

Points: 1 out of 1

Question 35 of 93

The Henderson-Hasselbalch equation show sthat

Correct answer: D)

You chose: D)

A)

dilution of a buffer increases its pH

B)

pH is a function of temperature

C)

pH - pka when an acid is tenth normal

D)

Page 25: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

pH - pka when an acid is half neutralized

E)

pH is independent of the dissociation

constant of the acid

Points: 1 out of 1

Question 36 of 93

In the absence of compensatory changes,

drop in blood pressure results from

Correct answer: E)

You chose: E)

A)

vasoconstriction.

B)

increased hematocrit.

C)

increased stroke volume

D)

increased cardiac output

E)

decreased venous return.

Points: 1 out of 1

Question 37 of 93

DNA damage by ultraviolet light is due to

Page 26: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: D)

You chose: C)

A)

alkylation of the guanine in DNA.

B)

excessive unwinding of the DNA molecule.

C)

frequent replacement in the DNA molecule of purines by pyrimidines.

D)

induction of dimerization by way of covalent bonds between adjacent thy mine groups.

Points: 0 out of 1

Question 38 of 93

Sucrose is a glycoside of which of the

following structures?

Correct answer: C)

You chose: C)

A)

4-D-glucose-α-D-galactopyranoside

B)

4-D-glucose-β-D-galactopyranoside

C)

α-D-glucopyranosido-β-D-fructofuranoside

D)

Page 27: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

β-D-glucopyranosido-β-D-fructofuranoside

Points: 1 out of 1

Question 39 of 93

Which of the following is a function of

vitamin B6 (pyridoxal phosphate)?

Correct answer: C)

You chose: C)

A)

Prevents pernicious anemia

B)

Allows adaptation to dim light

C)

Acts as coenzyme in transamination reactions

D)

Prevents microcytic hypochromic anemia

Points: 1 out of 1

Question 40 of 93

Carbon monoxide decreases the amount of

Correct answer: C)

You chose: E)

A)

bicarbonate in the blood plasma.

Page 28: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

B)

carbonic anhydrase available in the lungs.

C)

oxygen that can be transported by hemoglobin.

D)

alveolar surface available for gaseous exchange.

E)

carbon dioxide that can be transported

by the blood.

Points: 0 out of 1

Question 41 of 93

The most likely cause of an increase in filtration fraction is

Correct answer: B)

You chose: E)

A)

elevation of ureteral pressure.

B)

efferent arteriolar constriction.

C)

afferent arteriolar constriction.

D)

elevation of renal vein pressure.

E)

elevation of plasma protein concentration

Page 29: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Points: 0 out of 1

Question 42 of 93

The two chains of double stranded DNA are

so arranged that

Correct answer: C)

You chose: A)

A)

they are parallel.

B)

heat does not affect interchain bonds.

C)

hydrophobic aromatic nitrogen bases are held close to each other.

D)

purines and pyrimidines alternate along each chain.

E)

an adenine residue on one chain is directly hydrogen bonded to-a cytosine on the other chain.

Points: 0 out of 1

Question 43 of 93

A deficiency of rhodopsin is most likely

caused by decreased dietary intake of

Correct answer: C)

You chose: C)

Page 30: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

glucose.

B)

adenine.

C)

vitamin A.

D)

tryptophan.

E)

riboflavin.

Points: 1 out of 1

Question 44 of 93

Removal of a molecule of water between the

carboxyl group of one amino acid and the

amino group of a second amino acid results

in formation of a

Correct answer: B)

You chose: B)

A)

zwitterion.

B)

peptide bond.

C)

hydrogen bond.

Page 31: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

glycosidic bond.

E)

hydrophobic bond.

Points: 1 out of 1

Question 45 of 93

The primary effect of calcitonin is to

Correct answer: B)

You chose: A)

A)

increase bone resorption.

B)

inhibit bone resorption.

C)

increase calcium absorption from the

intestine.

D)

decrease calcium absorption from the

intestine.

Points: 0 out of 1

Question 46 of 93

The belief that the secretion of saliva is an active process is supported by the observation that

Correct answer: D)

Page 32: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

You chose: D)

A)

during secretion, there is vasodilation within the gland.

B)

during secretion, blood flow through the gland is unchanged.

C)

during secretion, blood flow through the gland is decreased.

D)

secretion continues even when the pressure within the salivary duct is higher than the blood pressure.

E)

secretion stops if the pressure within the salivary duct is the same as the blood pressure.

Points: 1 out of 1

Question 47 of 93

Which of the following enzymes catalyzes

the formation of uric acid from purines?

Correct answer: C)

You chose: D)

A)

Urease

B)

Uricase

C)

Page 33: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Xanthine oxidase

D)

Aspartate transcarbamylase

E)

Carbamyl phosphate synthetase

Points: 0 out of 1

Question 48 of 93

The process by which extensor muscles acting at a particular joint are inhibited by stretch of the flexor muscle acting at the same joint is

Correct answer: E)

You chose: C)

A)

myotatic reflex.

B)

clasp-knife reflex.

C)

monosynaptic reflex.

D)

lateral inhibition.

E)

reciprocal inhibition.

Points: 0 out of 1

Question 49 of 93

Carbon dioxide or bicarbonate is required in the biosynthesis of fatty acids because

Page 34: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: C)

You chose: C)

A)

the bicarbonate/carbonic acid buffer system is very efficient at the pH optimum of this sensitive enzyme system.

B)

bicarbonate is a positive effector for this system and favorably alters the conformation of its enzymes,

C)

carbon dioxide is incorporated into acetyl coenzyme A forming malonyl coenzyme A, an intermediate in the synthetic process.

D)

carbon dioxide is incorporated into carbamyl phosphate, a reactive intermediate in the synthetic process.

Points: 1 out of 1

Question 50 of 93

Any substance that is filtered by glomeruli

and secreted, but not reabsorbed, by renal

tubules will have a renal clearance that is

Correct answer: D)

You chose: E)

A)

equal to the clearance of urea,

Page 35: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

B)

equal to the clearance of inulin.

C)

less than the clearance of inulin.

D)

greater than the clearance of inulin.

E)

equal to the glomerular filtration rate.

Points: 0 out of 1

Question 51 of 93

Energy for ATP synthesis is derived from the

electron transport system by which of the

following processes?

Correct answer: E)

You chose: A)

A)

Transamination

B)

Aldolization

C)

Reductive synthesis

D)

Oxidative deamination

E)

Page 36: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Oxidative phosphorylation

Points: 0 out of 1

Question 52 of 93

Which of the following statements is true

concerning fatty acid synthesis and fatty acid

breakdown?

Correct answer: B)

You chose: B)

A)

Both are mitochondria! functions.

B)

Both require phosphopantothenic acid.

C)

Both share common electron donors and acceptors.

D)

Both share common enzymes for

oxidation and reduction reactions.

Points: 1 out of 1

Question 53 of 93

The function of rhythmic segmentation is

chiefly that of

Correct answer: B)

You chose: B)

Page 37: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

macerating food.

B)

mixing food with digestive secretions.

C)

increasing the surface available for absorption.

D)

transporting material down the gastrointestinal tract.

Points: 1 out of 1

Question 54 of 93

Lipids are most characteristic of which of the

following cellular components?

Correct answer: C)

You chose: C)

A)

Cytoplasm

B)

Ribosomes

C)

Membranes

D)

Chromosomes

Points: 1 out of 1

Page 38: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Question 55 of 93

Which of the following is true of the Tm (melting temperature) of a given DNA double helix?

Correct answer: A)

You chose: D)

A)

Is a function of the base composition

B)

Can be used to accurately predict its molecular weight

C)

Can be measured by observing the change in chemical composition

D)

Is higher If individual strands of the DNA double helix are parallel rather than antiparallel

Points: 0 out of 1

Question 56 of 93

A submaximal direct stimulus to a skeletal musde causes

Correct answer: B)

You chose: B)

A)

contraction of no fibers.

B)

contraction of some fibers.

C)

Page 39: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

partial contraction of all fibers in the muscle.

D)

less contraction than with a subminimal stimulus.

E)

more contraction than with a maximal

stimulus.

Points: 1 out of 1

Question 57 of 93

Over a period of time, a man uses 4 liters of

oxygen and produces 3 liters of CO2. What

is his RQ for that period?

Correct answer: A)

You chose: A)

A)

0.75

B)

1.00

C)

1.33

D)

7.00

Points: 1 out of 1

Question 58 of 93

The gallbladder is caused to contract by the

Page 40: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Hormone

Correct answer: E)

You chose: D)

A)

gastnn.

B)

secretin.

C)

pancreozymin.

D)

enterogastrone.

E)

cholecystokinin.

Points: 0 out of 1

Question 59 of 93

The partial pressure of oxygen in arterial

blood is lower than that in alveoli. The

condition suggested is

Correct answer: E)

You chose: E)

A)

hyperventilation.

Page 41: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

B)

slow blood flow.

C)

high blood pressure.

D)

inadequate ventilation.

E)

thickening of the alveolar membrane.

Points: 1 out of 1

Question 60 of 93

Which of the following tissues is primarily

responsible for formation of urea?

Correct answer: A)

You chose: A)

A)

Liver

B)

Brain

C)

Kidney

D)

Muscle

Points: 1 out of 1

Question 61 of 93

Page 42: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

In which of the following situations is an

osmotic diuresis observed?

Correct answer: A)

You chose: A)

A)

During diabetes mellitus

B)

During water deprivation

C)

Following ingestion of starch

D)

Following injection of Pitressin

Points: 1 out of 1

Question 62 of 93

Which of the following causes some degree

of temporary alkalosis?

Correct answer: A)

You chose: A)

A)

Hyperventilation

B)

High fluid intake

Page 43: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

C)

Excessive smoking

D)

Severe muscular effort

E)

Ingestion of ammonium chloride

Points: 1 out of 1

Question 63 of 93

Which of the following enzymes is involved in the termination of neuromuscular transmission?

Correct answer: E)

You chose: E)

A)

Choline acetylase

B)

Monoamine oxidase

C)

Methyltransferase

D)

Adenylate cyclase

E)

Acetylcholine esterase

F)

Catecholamine-ortho-methyltransferase

Points: 1 out of 1

Page 44: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Question 64 of 93

A muscle devoid of tonus is

Correct answer: A)

You chose: A)

A)

atonic.

B)

spastic.

C)

hypotonic.

D)

hypertonic.

Points: 1 out of 1

Question 65 of 93

Which of the following characterizes an asymmetric carbon?

Correct answer: B)

You chose: C)

A)

A carbon atom with four identical groups attached to it

B)

A carbon atom with four different groups attached to it

C)

Page 45: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A carbon with at least one carboxyl and one ammo group attached to it

D)

A carbon atom that has two heavy groups on one side and two light groups on the other

Points: 0 out of 1

Question 66 of 93

Which of the following statements supports the observation that the glomerulus acts like a simple physical microfilter?

Correct answer: D)

You chose: C)

A)

Potassium ion is both secreted and reabsorbed by the nephron.

B)

Antidiuretic hormone alters permeability of the tubular cell membrane.

C)

Glomerular filtration rate is determined by plasma clearance of inulin.

D)

Increased concentration of colloids in plasma diminishes the formation of filtrate.

E)

The afferent arteriole is greater in diameter than the efferent arteriole.

Points: 0 out of 1

Question 67 of 93

Hydroxylation of proline and lysine during

collagen biosynthesis occurs

Page 46: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: A)

You chose: A)

A)

after translation.

B)

in the mitochondria! matrix.

C)

before formation of their respective amino acyl-t-RNA's.

D)

while proline or lysine is bound to the peptidyl (P) site on the ribosome.

Points: 1 out of 1

Question 68 of 93

Which of the following is most likely to

promote depolymerization of the ground

substance?

Correct answer: D)

You chose: E)

A)

Cortisone

B)

Collagenase

C)

Chymotrypsin

Page 47: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

Hyaluronidase

E)

Ammonium phosphate

Points: 0 out of 1

Question 69 of 93

Prostaglandins are made within cells

Correct answer: E)

You chose: B)

A)

on an RNA template.

B)

on rough endoplasmic reticulum

C)

from methionine.

D)

from progesterone.

E)

from polyunsaturated fatty acids.

Points: 0 out of 1

Question 70 of 93

Thyroid secretion is stimulated by

Correct answer: E)

Page 48: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

You chose: E)

A)

hypoxia.

B)

propylthiouracil.

C)

exogenous thyroid hormone.

D)

high serum iodide concentration.

E)

prolonged exposure to a cold environment.

F)

prolonged exposure to a warm

environment.

Points: 1 out of 1

Question 71 of 93

Following exercise, ventilation is in excess of

the metabolic requirement. During this period, the level of lactic acid in blood

Correct answer: B)

You chose: A)

A)

increases.

B)

Page 49: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

decreases.

C)

remains unchanged.

Points: 0 out of 1

Question 72 of 93

Which of the following vitamins can be

supplied to humans by the normal action of

intestinal flora?

Correct answer: D)

You chose: D)

A)

A

B)

D

C)

E

D)

K

E)

None of the above

Points: 1 out of 1

Question 73 of 93

Some amino acids need not be present in the diet of an animal because of the animal's ability to synthesize the acids at an adequate rate. A principal source of carbon for these amino acids is

Page 50: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: C)

You chose: C)

A)

nucleic acids.

B)

carbon dioxide.

C)

metabolism of carbohydrates.

D)

methylene folic acid derivatives.

Points: 1 out of 1

Question 74 of 93

Distribution of fluids between intracellular and extracellular compartments is mainly achieved by

Correct answer: C)

You chose: D)

A)

bulk flow across the capillary wall.

B)

unrestricted movement of sodium to achieve osmotic balance.

C)

unrestricted movement of water to achieve osmotic balance.

D)

Page 51: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

unrestricted movement of both sodium and potassium to achieve osmotic balance.

E)

movement of potassium out of the intracellular compartment to achieve osmotic balance.

Points: 0 out of 1

Question 75 of 93

The sensory organs concerned with

maintenance of skeletal muscle tonus are

Correct answer: A)

You chose: A)

A)

muscle spindles.

B)

gamma efferents.

C)

pacinian corpuscles.

D)

golgi tendon organs.

Points: 1 out of 1

Question 76 of 93

An electrocardiogram showing extra P waves

before each QRS complex indicates

Correct answer: C)

You chose: C)

Page 52: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

fibrillation.

B)

atrial bradycardia

C)

partial heart block.

D)

ventricular tachycardia.

E)

left bundle branch block.

Points: 1 out of 1

Question 77 of 93

In which of the following parts of the circulatory system is blood pressure the lowest?

Correct answer: B)

You chose: D)

A)

Aorta

B)

Veins

C)

Arterioles

D)

Capillaries

Page 53: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

E)

Large arteries

Points: 0 out of 1

Question 78 of 93

Carbohydrate is stored in the body principally as

Correct answer: D)

You chose: A)

A)

glucose.

B)

maltose.

C)

sucrose.

D)

glycogen.

E)

glycosaminoglycans.

Points: 0 out of 1

Question 79 of 93

Within physiologic limits, activity of the

respiratory center is decreased directly by

Correct answer: B)

You chose: A)

Page 54: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

decreased pH.

B)

increased pH.

C)

increased hemoglobin concentration.

D)

increased plasma carbon dioxide partial

pressure.

Points: 0 out of 1

Question 80 of 93

The tone of the rmasseter muscle is

maintained by the

Correct answer: B)

You chose: C)

A)

flexor reflex.

B)

stretch reflex.

C)

crossed-extensor reflex.

D)

continuous production of metabolic

Page 55: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

products.

Points: 0 out of 1

Question 81 of 93

The air remaining in alveoli at the end of a

forced maximal expiration is the

Correct answer: C)

You chose: C)

A)

tidal volume.

B)

vital capacity,

C)

residual volume.

D)

expiratory reserve volume.

E)

inspiratory reserve volume.

Points: 1 out of 1

Question 82 of 93

The plasma membrane can be best described

Correct answer: F)

You chose: F)

Page 56: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

A)

a static trilamellar lipid-protein-lipid sheath.

B)

a static mosaic composed primarily of lipids and proteins.

C)

an unorganized zone between cytoplasm and interstitial fluid.

D)

a membrane whose composition is essentially constant for all mammalian cells.

E)

a fluid mosaic composed of neutral fats and glycoproteins.

F)

a fluid mosaic composed primarily of phospholipids, cholesterol and glycoproteins.

Points: 1 out of 1

Question 83 of 93

Which of the following molecules is NOT

part of the mammalian cell membrane?

Correct answer: A)

You chose: A)

A)

Endotoxin

B)

Cardiolipin

C)

Piasmalogen

Page 57: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

Proteoglycan

E)

Upopolysaccharide

Points: 1 out of 1

Question 84 of 93

Which of the following hormones does NOT

induce activation of adenylate cyclase?

Correct answer: A)

You chose: C)

A)

Insulin

B)

Glucagon

C)

Epinephrine

D)

Parathyroid hormone

Points: 0 out of 1

Question 85 of 93

Which of the following is least soluble in

solutions with low pH?

Correct answer: B)

Page 58: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

You chose: A)

A)

Chlorapatite

B)

Fluorapatite

C)

Hydroxyapatite

D)

Calcium fluoride

Points: 0 out of 1

Question 86 of 93

All of the following function in buffer

Systems in the blood EXCEPT

Correct answer: A)

You chose: A)

A)

NaCl.

B)

H2CO3.

C)

NaHCO.

D)

Na2HPO4.

Page 59: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

E)

NaH2PO4.

Points: 1 out of 1

Question 87 of 93

Which of the following compounds does

NOT contain a high-energy bond?

Correct answer: D)

You chose: D)

A)

ATP

B)

Acetyl CoA

C)

UDP-glucose

D)

Glucose-6-phosphate

E)

Phosphoenolypyruvate

Points: 1 out of 1

Question 88 of 93

Which of the following is NOT a cofactor or

a substance involved in hydroxylation of

praline during collagen biosynthesis?

Page 60: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: B)

You chose: C)

A)

Ascorbate

B)

Ergosterol

C)

Ferrous ion

D)

α-ketoglutarate

Points: 0 out of 1

Question 89 of 93

Which of the following statements is NOT true about ammonia and the a-amino group of amino acids?

Correct answer: B)

You chose: D)

A)

NH+4 is formed from glutamine in the kidney.

B)

The amino group in carbamyl Phosphate is directly donated by aspartate in a transamination reaction.

C)

Cellular levels of ammonia must be maintained at low concentrations because of its toxicity.

Page 61: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

D)

Glutamate dehydrogenase can catalyze the formation of glutamate from ammonia and α-ketoglutarate using

NADPH as a cofactor.

Points: 0 out of 1

Question 90 of 93

Which of the following is NOT a

monosaccharide?

Correct answer: A)

You chose: A)

A)

Arnylose

B)

Glucose

C)

Fructose

D)

Glyceraldehyde

E)

Glucuronic acid

Points: 1 out of 1

Question 91 of 93

Which of the following statements is NOT true concerning fluoride?

Page 62: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

Correct answer: C)

You chose: D)

A)

It is excreted rapidly by the kidney.

B)

It is deposited in calcified tissues.

C)

It occurs only in the ionic form in plasma.

D)

It passes the placental barrier relatively slowly.

E)

At 1 ppm. in water, it is tasteless, odorless and colorless.

Points: 0 out of 1

Question 92 of 93

Hydrolysis of nucleic acids is likely to yield

all of the following EXCEPT

Correct answer: D)

You chose: D)

A)

ribose.

B)

adenine.

C)

Page 63: 1987 NBDE 1 ASDA (Biochemistry & Physiology )

deoxyribose.

D)

acetic acid.

E)

phosphoric acid.

Points: 1 out of 1

Question 93 of 93

Which of the following compounds is NOT

involved in coagulation of blood?

Correct answer: A)

You chose: A)

A)

Fe +2

B)

Ca +2

C)

Prothrombin

D)

Fibnnogen

E)

Thromboplastin